ATE458491T1 - Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin - Google Patents
Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocinInfo
- Publication number
- ATE458491T1 ATE458491T1 AT06802456T AT06802456T ATE458491T1 AT E458491 T1 ATE458491 T1 AT E458491T1 AT 06802456 T AT06802456 T AT 06802456T AT 06802456 T AT06802456 T AT 06802456T AT E458491 T1 ATE458491 T1 AT E458491T1
- Authority
- AT
- Austria
- Prior art keywords
- oxytocin
- administration
- treating headache
- headache
- treatment
- Prior art date
Links
- 206010019233 Headaches Diseases 0.000 title abstract 3
- 231100000869 headache Toxicity 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 101800000989 Oxytocin Proteins 0.000 title abstract 2
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 title 1
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 title 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title 1
- 229960001723 oxytocin Drugs 0.000 title 1
- 208000027109 Headache disease Diseases 0.000 abstract 1
- 206010044652 trigeminal neuralgia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71195005P | 2005-08-26 | 2005-08-26 | |
| US79400406P | 2006-04-21 | 2006-04-21 | |
| PCT/US2006/033500 WO2007025249A2 (en) | 2005-08-26 | 2006-08-28 | Methods for treatment of headaches by administration of oxytocin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE458491T1 true ATE458491T1 (de) | 2010-03-15 |
Family
ID=37654909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06802456T ATE458491T1 (de) | 2005-08-26 | 2006-08-28 | Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin |
Country Status (9)
| Country | Link |
|---|---|
| US (9) | US20070093420A1 (de) |
| EP (3) | EP2179741B1 (de) |
| JP (4) | JP5276982B2 (de) |
| AT (1) | ATE458491T1 (de) |
| AU (1) | AU2006282799B2 (de) |
| CA (2) | CA2620202C (de) |
| DE (1) | DE602006012513D1 (de) |
| IL (1) | IL189777A0 (de) |
| WO (2) | WO2007025286A2 (de) |
Families Citing this family (167)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8481043B2 (en) * | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
| US9078892B2 (en) * | 2004-02-26 | 2015-07-14 | Allergan, Inc. | Methods for treating pain and for treating a medication overuse disorder |
| US20050191321A1 (en) | 2004-02-26 | 2005-09-01 | Allergan, Inc. | Methods for treating headache |
| US20100266638A1 (en) | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
| ATE458491T1 (de) * | 2005-08-26 | 2010-03-15 | Univ Leland Stanford Junior | Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin |
| AU2006304392B2 (en) * | 2005-10-18 | 2014-05-01 | National Jewish Health | Conditionally immortalized long-term stem cells and methods of making and using such cells |
| RS20080200A (sr) | 2005-11-14 | 2009-07-15 | Rinat Neuroscience Corp., | Antagonistička antitela usmerena protiv kalcitonina, peptida povezanog sa genom, i postupak njihovog korišćenja |
| US20080261893A1 (en) * | 2006-02-24 | 2008-10-23 | Denise Barbut | Topical corneal analgesia using neurotensin receptor agonists and synergistic neurotensin combinations without delaying wound healing |
| WO2007120485A2 (en) * | 2006-03-30 | 2007-10-25 | Cinergen, Llc | Methods of treating pain with alkylxanthines and antiepileptics and compositions for use therefor |
| GB2438834A (en) | 2006-06-08 | 2007-12-12 | Optinose As | Intranasal protein administration |
| US7645767B2 (en) * | 2006-08-31 | 2010-01-12 | Trinity Laboratories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
| CA2680704A1 (en) * | 2007-03-12 | 2008-09-18 | Sarentis Therapeutics, Inc. | Topical corneal analgesia using neurotensin receptor agonists and synergistic neurotensin combinations without delaying wound healing |
| EP2583550A1 (de) * | 2007-03-13 | 2013-04-24 | National Jewish Health | Verfahren zur Erzeugung von Antikörpern |
| US9707274B2 (en) | 2007-06-08 | 2017-07-18 | Healthpartners Research & Education | Methods for preventing and treating post-traumatic stress disorder (PTSD) |
| CA2687505C (en) * | 2007-06-08 | 2013-10-08 | Healthpartners Research Foundation | Pharmaceutical compositions and methods for enhancing targeting of therapeutic compounds to the central nervous system |
| US20100221200A1 (en) * | 2007-07-17 | 2010-09-02 | The Ohio State University Research Foundation | Compositions and methods for skin care |
| WO2009033489A2 (en) * | 2007-09-11 | 2009-03-19 | Glostrup Hospital | Selective pacl inhibitors for use in the treatment of migraine and headaches |
| AU2008303945A1 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
| US20100234306A1 (en) * | 2007-09-11 | 2010-09-16 | Dorian Bevec | Use of a peptide as a therapeutic agent |
| RU2010113977A (ru) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | Применение антагониста рецептора фибриногена и/или пептид фолликулярного гонадолиберина в качестве терапевтического средства при лечении инфекции streptococcus pneumoniae |
| KR20100075438A (ko) * | 2007-09-11 | 2010-07-02 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 펩티드의 용도 |
| US8293239B2 (en) | 2008-03-04 | 2012-10-23 | Pfizer Limited | Methods of treating chronic pain |
| US20110117106A1 (en) * | 2008-03-06 | 2011-05-19 | Alice Prince | Uses of calpain inhibitors to inhibit inflammation |
| US20090246273A1 (en) * | 2008-03-27 | 2009-10-01 | Al-Ghananeem Abeer M | Ketorolac Sublingual Spray for the Treatment of Pain |
| SG10201803982TA (en) * | 2008-05-16 | 2018-07-30 | Taiga Biotechnologies Inc | Antibodies and processes for preparing the same |
| FR2932483A1 (fr) | 2008-06-13 | 2009-12-18 | Cytomics Systems | Composes utiles pour le traitement des cancers. |
| AU2009274172B2 (en) * | 2008-07-21 | 2015-08-13 | Htyr Acquisition Llc | Differentiated anucleated cells and method for preparing the same |
| EP2966084B1 (de) | 2008-08-28 | 2018-04-25 | Taiga Biotechnologies, Inc. | Myc-modulatoren, verfahren zur verwendung davon und verfahren zur identifikation von mitteln zur myc-modulierung |
| WO2010029555A1 (en) * | 2008-09-12 | 2010-03-18 | Slender Medical, Ltd. | Virtual ultrasonic scissors |
| US20110318345A1 (en) * | 2008-09-15 | 2011-12-29 | Optinose As | Nasal delivery |
| CA2739936C (en) * | 2008-10-17 | 2017-12-12 | Pharmacofore, Inc. | Pharmaceutical compositions with attenuated release of phenolic opioids |
| EP2373680A4 (de) | 2008-12-08 | 2017-05-24 | Biousian Biosystems, Inc | Selektive delta-opioidrezeptor-analgetika |
| CN102405044A (zh) * | 2009-02-06 | 2012-04-04 | 南加利福尼亚大学 | 含有单萜的治疗组合物 |
| SG176000A1 (en) * | 2009-05-13 | 2011-12-29 | Protein Delivery Solutions Llc | Pharmaceutical system for trans-membrane delivery |
| JP5669145B2 (ja) * | 2009-07-02 | 2015-02-12 | 国立大学法人山口大学 | 表面麻酔剤 |
| SG177752A1 (en) | 2009-07-27 | 2012-03-29 | Trigemina Inc | Methods for treatment of pain |
| FR2948809B1 (fr) * | 2009-07-31 | 2012-08-17 | St Microelectronics Rousset | Amplificateur de lecture faible puissance auto-minute |
| CA2771186C (en) | 2009-08-28 | 2018-01-02 | Rinat Neuroscience Corporation | Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide |
| PH12012500485A1 (en) | 2009-09-08 | 2012-10-22 | Signature Therapeutics Inc | Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof |
| AU2010330747B2 (en) * | 2009-12-18 | 2016-08-11 | Achelios Therapeutics, Inc. | Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions |
| US8622993B2 (en) * | 2009-12-18 | 2014-01-07 | Healthpartners Research Foundation | Device and method for delivering therapeutic substances to the maxillary sinus of a patient |
| US20110184322A1 (en) * | 2010-01-22 | 2011-07-28 | Slender Medical Ltd. | Method and device for treatment of keloids and hypertrophic scars using focused ultrasound |
| BR112012022209A2 (pt) | 2010-03-03 | 2017-06-06 | Neonc Tech Inc | composições farmacêuticas compreendendo monoterpenos |
| WO2011133179A1 (en) * | 2010-04-21 | 2011-10-27 | Pharmacofore, Inc | Compositions comprising enzyme-cleavable hydromorphone prodrug |
| US20110262355A1 (en) | 2010-04-21 | 2011-10-27 | Jenkins Thomas E | Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof |
| ES2710617T3 (es) | 2010-04-21 | 2019-04-26 | Signature Therapeutics Inc | Composiciones que comprenden profármacos de anfetamina escindibles enzimáticamente e inhibidores de los mismos |
| WO2011133178A1 (en) | 2010-04-21 | 2011-10-27 | Pharmacofore, Inc | Compositions comprising enzyme-cleavable phenol-modified tapentadol prodrug |
| US9242122B2 (en) | 2010-05-14 | 2016-01-26 | Liat Tsoref | Reflectance-facilitated ultrasound treatment and monitoring |
| US8617150B2 (en) | 2010-05-14 | 2013-12-31 | Liat Tsoref | Reflectance-facilitated ultrasound treatment |
| US8956346B2 (en) | 2010-05-14 | 2015-02-17 | Rainbow Medical, Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
| EP2571511B1 (de) | 2010-05-18 | 2014-10-08 | Université de Genève | Neue verwendungsarten für oxytocin-like-moleküle und zugehörige verfahren |
| WO2012003968A1 (en) * | 2010-07-06 | 2012-01-12 | Grünenthal GmbH | Novel gastro- retentive dosage forms comprising a gaba analog and an opioid |
| US20160038600A1 (en) | 2012-08-03 | 2016-02-11 | Neonc Technologies Inc. | Pharmaceutical compositions comprising poh derivatives |
| ES3034958T3 (en) | 2010-08-27 | 2025-08-27 | Univ Southern California | Pharmaceutical compositions comprising derivatives of perillyl alcohol |
| GB201015371D0 (en) * | 2010-09-14 | 2010-10-27 | Optinose As | Nasal delivery |
| US8647661B1 (en) * | 2010-11-05 | 2014-02-11 | Florida A&M University | Surface modified multilayered nanostructures for dermal delivery |
| US9211269B2 (en) | 2010-12-17 | 2015-12-15 | Neonc Technologies Inc. | Methods and devices for using isoperillyl alcohol |
| US8497237B2 (en) | 2011-01-11 | 2013-07-30 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable oxycodone prodrug |
| RU2609412C2 (ru) | 2011-01-11 | 2017-02-01 | Сигничер Терапьютикс, Инк. | Композиции, содержащие расщепляемое ферментами пролекарство оксикодона |
| US20120183580A1 (en) * | 2011-01-13 | 2012-07-19 | Theralpha | Analgesic Composition for Transbuccal Administration |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US11523934B2 (en) | 2011-02-04 | 2022-12-13 | Seed Health, Inc. | Method and system to facilitate the growth of desired bacteria in a human's mouth |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US10687975B2 (en) * | 2011-02-04 | 2020-06-23 | Joseph E. Kovarik | Method and system to facilitate the growth of desired bacteria in a human's mouth |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| WO2012122420A2 (en) | 2011-03-09 | 2012-09-13 | Pharmacofore, Inc. | Opioid prodrugs with heterocyclic linkers |
| CN103813800B (zh) | 2011-03-09 | 2017-12-19 | 特色疗法股份有限公司 | 具有杂环连接物的活性剂前药 |
| US9949923B2 (en) | 2011-03-15 | 2018-04-24 | Optinose As | Nasal delivery |
| EP3449917A3 (de) | 2011-04-05 | 2019-06-05 | Grünenthal GmbH | Tapentadol zur vorbeugung der schmerzchronifizierung |
| PL2694050T3 (pl) * | 2011-04-05 | 2020-03-31 | Grünenthal GmbH | Tapentadol do stosowania w leczeniu bólu związanego z nerwobólami nerwu trójdzielnego |
| HRP20171570T1 (hr) | 2011-04-29 | 2017-11-17 | Grünenthal GmbH | Tapentadol za sprječavanje i liječenje depresije i tjeskobe |
| US8609088B2 (en) | 2011-05-10 | 2013-12-17 | Regents Of The University Of Minnesota | Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases |
| US8987199B2 (en) | 2011-06-15 | 2015-03-24 | Nerve Access, Inc. | Pharmaceutical compositions for intranasal administration for the treatment of neurodegenerative disorders |
| WO2013067309A1 (en) * | 2011-11-04 | 2013-05-10 | Xion Pharmaceutical Corporation | Methods and compositions for oral administration of melanocortin receptor agonist compounds |
| US11213501B2 (en) | 2011-12-27 | 2022-01-04 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| US9962391B2 (en) | 2011-12-27 | 2018-05-08 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| US9468599B2 (en) | 2011-12-27 | 2016-10-18 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| US11213500B2 (en) | 2011-12-27 | 2022-01-04 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| US10813897B2 (en) | 2011-12-27 | 2020-10-27 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| CA2856451A1 (en) * | 2012-01-05 | 2013-07-11 | Beech Tree Labs, Inc. | Method of treating pain by administration of nerve growth factor |
| US9707414B2 (en) | 2012-02-14 | 2017-07-18 | Rainbow Medical Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
| US9308163B2 (en) | 2012-02-15 | 2016-04-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of treating and preventing diseases and disorders of the central nervous system |
| CN110643576A (zh) | 2012-07-20 | 2020-01-03 | 泰加生物工艺学公司 | 造血区室的增强的重建和自动重建 |
| ES2442242B1 (es) * | 2012-08-09 | 2014-11-25 | Biotechnology Institute, I Mas D, S.L. | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
| US10004557B2 (en) | 2012-11-05 | 2018-06-26 | Pythagoras Medical Ltd. | Controlled tissue ablation |
| US9770593B2 (en) | 2012-11-05 | 2017-09-26 | Pythagoras Medical Ltd. | Patient selection using a transluminally-applied electric current |
| WO2014085571A1 (en) * | 2012-11-28 | 2014-06-05 | Nektar Therapeutics | Method for assessing and predicting efficacy of breast cancer treatment with a long-acting topoisomerase i inhibitor |
| US9050330B2 (en) * | 2012-12-06 | 2015-06-09 | Jose C. Ramon-de-Jesus | Method, composition and kit for treating frequent headaches |
| US10639439B2 (en) | 2013-01-30 | 2020-05-05 | Midwest Pharmaceuticals, Llc | Smokeless THC and administration method thereof |
| WO2014130581A1 (en) * | 2013-02-20 | 2014-08-28 | Questcor Pharmaceuticals, Inc. | Acth for treatment of migraine headache |
| US9365825B2 (en) | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| US10272115B2 (en) | 2013-03-11 | 2019-04-30 | Taiga Biotechnologies, Inc. | Production and use of red blood cells |
| EA032830B1 (ru) | 2013-03-15 | 2019-07-31 | Эмджен Инк. | Антитела к pac1 человека и их применение для лечения головной боли |
| SG11201509419QA (en) | 2013-05-15 | 2015-12-30 | Univ Minnesota | Adeno-associated virus mediated gene transfer to the central nervous system |
| US20150086616A1 (en) * | 2013-09-20 | 2015-03-26 | Steven Lehrer | Method for the prevention and treatment of alzheimer's disease |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| KR102274964B1 (ko) | 2014-03-21 | 2021-07-09 | 테바 파마슈티컬스 인터내셔널 게엠베하 | 칼시토닌 유전자-관련 펩티드에 대한 길항제 항체 및 그의 사용 방법 |
| US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| EP3139853B1 (de) | 2014-05-07 | 2018-12-19 | Pythagoras Medical Ltd. | Apparat zur gesteuerten gewebeablation |
| US20150359738A1 (en) * | 2014-06-16 | 2015-12-17 | Loewi LLC | Methods of Anesthetizing Nerve Tissue in the Trigeminal Nerve Pathway and Medical Uses Thereof |
| CA2960756C (en) | 2014-09-15 | 2023-08-01 | Amgen Inc. | Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof |
| JP6607508B2 (ja) * | 2014-10-01 | 2019-11-20 | オキシトーン バイオサイエンス ビー.ブイ. | 分娩制御物質を含有する口腔内崩壊性固形医薬投与単位 |
| RU2701199C2 (ru) * | 2014-10-01 | 2019-09-25 | Окситон Байосайенс Б.В. | Перорально распадающаяся твердая фармацевтическая единица дозирования, содержащая контролирующее родовую деятельность вещество |
| EP3848028B9 (de) | 2014-10-20 | 2024-10-16 | Oyster Point Pharma, Inc. | Verfahren zur behandlung von augenleiden |
| US10388407B2 (en) | 2014-10-21 | 2019-08-20 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| EP3209803A4 (de) | 2014-10-21 | 2018-06-13 | Ubiome, Inc. | Verfahren und zusammensetzungen für mikrobiom-diagnostika und -therapeutika |
| CA2966802C (en) | 2014-11-19 | 2022-11-15 | Optinose As | Intranasal administration |
| JP2017536421A (ja) * | 2014-12-01 | 2017-12-07 | アケリオス セラピューティクス,インコーポレーテッド | 片頭痛及び疼痛に関連する状態を処置するための方法及び組成物 |
| US11389473B2 (en) * | 2015-01-07 | 2022-07-19 | Tonix Pharmaceuticals Holding Corp. | Magnesium-containing oxytocin formulations and methods of use |
| US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| JP6674957B2 (ja) | 2015-02-12 | 2020-04-01 | ネオンク テクノロジーズ インク. | ペリリルアルコール誘導体を含む医薬組成物 |
| WO2016140063A1 (ja) * | 2015-03-04 | 2016-09-09 | 栄研化学株式会社 | オキシトシンの高感度測定法 |
| JP6924148B2 (ja) | 2015-04-16 | 2021-08-25 | ハー・ルンドベック・アクチエゼルスカベット | 抗pacap抗体及びそれらの使用 |
| US10383685B2 (en) | 2015-05-07 | 2019-08-20 | Pythagoras Medical Ltd. | Techniques for use with nerve tissue |
| US11207461B2 (en) | 2015-07-30 | 2021-12-28 | Anoop U. R | Drug delivery system and method for controlled and continuous delivery of drugs into the brain by bypassing the blood brain barrier |
| US11213480B1 (en) | 2015-08-06 | 2022-01-04 | Hikma Pharmaceuticals International Limited | Phenylephrine hydrochloride ready-to-use solution |
| CA2998708C (en) | 2015-10-01 | 2019-09-03 | Elysium Therapeutics, Inc. | Polysubunit opioid prodrugs resistant to overdose and abuse |
| US10335406B2 (en) | 2015-10-01 | 2019-07-02 | Elysium Therapeutics, Inc. | Opioid compositions resistant to overdose and abuse |
| EP3390447A1 (de) | 2015-12-15 | 2018-10-24 | Amgen Inc. | Pacap-antikörper und verwendungen davon |
| SMT202500100T1 (it) | 2016-04-12 | 2025-05-12 | Tonix Pharma Ltd | Formulazioni di ossitocina contenenti magnesio e metodi d'uso |
| BR112018071156A2 (pt) | 2016-04-15 | 2019-03-12 | The Trustees Of The University Of Pennsylvania | terapia de gene para tratar mucopolissacaridose tipo ii |
| KR20190005873A (ko) | 2016-04-15 | 2019-01-16 | 앨더 바이오파마슈티컬즈, 인코포레이티드 | 항-pacap 항체 및 그의 용도 |
| EP3457975A2 (de) | 2016-05-18 | 2019-03-27 | Pythagoras Medical Ltd. | Spiralförmiger katheter |
| FI3515937T3 (fi) | 2016-09-23 | 2026-02-11 | Teva Pharmaceuticals Int Gmbh | Refraktaarisen migreenin hoito |
| WO2018094376A1 (en) * | 2016-11-21 | 2018-05-24 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| WO2018102412A1 (en) | 2016-11-30 | 2018-06-07 | Neonc Technologies, Inc. | A perillyl alcohol-3 bromopyruvate conjugate and methods of treating cancer |
| US10583156B2 (en) | 2016-12-02 | 2020-03-10 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| US10456419B2 (en) | 2017-02-27 | 2019-10-29 | Payman Sadeghi | Method for treating migraine headaches |
| US10932711B2 (en) | 2017-02-27 | 2021-03-02 | Payman Sadeghi | Method and system for neurohydrodissection |
| CA3056239C (en) | 2017-03-17 | 2023-09-12 | Elysium Therapeutics, Inc. | Polysubunit opioid prodrugs resistant to overdose and abuse |
| US10149898B2 (en) | 2017-08-03 | 2018-12-11 | Taiga Biotechnologies, Inc. | Methods and compositions for the treatment of melanoma |
| KR102883778B1 (ko) | 2017-09-22 | 2025-11-12 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Ii형 점액다당류증의 치료를 위한 유전자 요법 |
| AR114080A1 (es) | 2018-01-12 | 2020-07-22 | Amgen Inc | Anticuerpos pac1 y sus usos |
| DK3749291T3 (da) | 2018-02-08 | 2024-04-08 | Univ Southern California | Fremgangsmåder til permeabilisering af blod-hjerne-barrieren |
| US20210346385A1 (en) * | 2018-09-21 | 2021-11-11 | MSB Holdings, Inc | Taste-masked dosage forms |
| US11135379B2 (en) | 2019-02-15 | 2021-10-05 | Bn Intellectual Properties, Inc. | Method of delivering pharmaceutical products |
| WO2020182322A1 (en) | 2019-03-14 | 2020-09-17 | Om Pharma Sa | Method of treating and/or preventing asthma, asthma exacerbations, allergic asthma and/or associated conditions with microbiota related to respiratory disorders |
| CN113874033A (zh) | 2019-04-08 | 2021-12-31 | 泰加生物工艺学公司 | 用于冷冻保存免疫细胞的组合物和方法 |
| JP2022532608A (ja) | 2019-05-14 | 2022-07-15 | タイガ バイオテクノロジーズ,インク. | T細胞疲弊を処置するための組成物および方法 |
| WO2021016190A1 (en) * | 2019-07-19 | 2021-01-28 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for modulating drug-use disorders |
| US11364225B2 (en) * | 2019-08-21 | 2022-06-21 | Bn Intellectual Properties, Inc. | Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same |
| JP2022546703A (ja) * | 2019-08-29 | 2022-11-07 | ニューヨーク ユニバーシティ | 耳鳴りの治療のためのオキシトシン組成物 |
| WO2021072055A1 (en) * | 2019-10-11 | 2021-04-15 | Board Of Regents, The University Of Texas System | Compositions and methods for preventing, reducing and reversing opioid-induced respiratory depression |
| NL2030835B1 (en) | 2020-01-24 | 2022-12-29 | Aim Immunotech Inc | Methods, compositions, and vaccinces for treating a virus infection |
| CA3189263A1 (en) * | 2020-08-10 | 2022-02-10 | Ziropa, Inc. | Compositions and methods for topical delivery |
| WO2023055830A1 (en) | 2021-09-29 | 2023-04-06 | Ensysce Biosciences, Inc. | Enzyme-cleavable methadone prodrugs and methods of use thereof |
| US20250099532A1 (en) * | 2022-01-27 | 2025-03-27 | Belnap Pharmaceuticals, Llc | Methods of treatment using oxytocin |
| AU2023375349A1 (en) * | 2022-11-07 | 2025-05-22 | AEON Biopharma, Inc. | Compositions for use in treating headache disorders |
| WO2025064708A1 (en) * | 2023-09-22 | 2025-03-27 | The George Washington University | Compositions comprising oxytocin and methods of treating opioid overdose |
| WO2025199179A2 (en) | 2024-03-18 | 2025-09-25 | Tonix Pharmaceuticals Holding Corp. | Oxytocin peptide analogs |
Family Cites Families (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US464378A (en) * | 1891-12-01 | Toilet-paper holder | ||
| US6413A (en) * | 1849-05-01 | Improved method of making wire-strengthened spoons | ||
| US2938891A (en) | 1956-03-30 | 1960-05-31 | Roussel Uclaf | Method of making oxytocin and intermediates thereof |
| US3076797A (en) * | 1957-07-22 | 1963-02-05 | Roussel Uclaf | Process of producing oxytocin and intermediates obtained thereby |
| US4213968A (en) * | 1978-06-05 | 1980-07-22 | Coy David Howard | Enkephalin derivatives |
| US4464378A (en) * | 1981-04-28 | 1984-08-07 | University Of Kentucky Research Foundation | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
| US4486441A (en) * | 1982-12-03 | 1984-12-04 | Merrell Toraude Et Compagnie | Pseudotropyl halogeno-benzoates and their use in migraine treatment |
| EP0223831B1 (de) | 1985-05-22 | 1992-07-15 | Liposome Technology, Inc. | Verfahren und system zum einatmen von liposomen |
| HU206890B (en) * | 1986-10-13 | 1993-01-28 | Sandoz Ag | Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components |
| JP2851627B2 (ja) * | 1987-10-15 | 1999-01-27 | シンテックス(ユー・エス・エイ)インコーポレイテッド | 粉末形態ポリプペチド類の経鼻投与 |
| US4885287A (en) * | 1988-08-09 | 1989-12-05 | University Of Kentucky Research Foundation | Novel method of administering aspirin and dosage forms containing same |
| ATE156704T1 (de) * | 1989-12-05 | 1997-08-15 | Ramsey Foundation | Neurologische wirkstoffe zur nasalen verabreichung an das gehirn |
| US5624898A (en) * | 1989-12-05 | 1997-04-29 | Ramsey Foundation | Method for administering neurologic agents to the brain |
| US6407061B1 (en) * | 1989-12-05 | 2002-06-18 | Chiron Corporation | Method for administering insulin-like growth factor to the brain |
| GB9202464D0 (en) | 1992-02-05 | 1992-03-18 | Danbiosyst Uk | Composition for nasal administration |
| GB9203769D0 (en) * | 1992-02-21 | 1992-04-08 | Sandoz Ltd | Improvements in or relating to organic compounds |
| DE4312913A1 (de) * | 1992-10-23 | 1994-10-13 | Knauf Siegfried | Medikamentenzusammensetzung Oxytocin, Vasopressin und alphabetagamma-Endorphine |
| SE9300937L (sv) * | 1993-03-19 | 1994-09-20 | Anne Fjellestad Paulsen | Komposition för oral administrering av peptider |
| US6054462A (en) * | 1994-04-13 | 2000-04-25 | Janssen Pharmaceutica, N.V. | Intranasal antimigraine compositions |
| EP0800828A4 (de) * | 1994-12-28 | 1999-03-31 | Teikoku Hormone Mfg Co Ltd | Transmucosale zubereitung |
| US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| CN1155368C (zh) * | 1996-02-27 | 2004-06-30 | 帝人株式会社 | 鼻腔给药的粉剂组合物 |
| US5855907A (en) * | 1997-03-24 | 1999-01-05 | Peyman; Gholam A. | Method of treatment of migraine |
| SE9701161D0 (sv) * | 1997-03-27 | 1997-03-27 | Karolinska Innovations Ab | New use I |
| SE9701162D0 (sv) * | 1997-03-27 | 1997-03-27 | Karolinska Innovations Ab | New use II |
| US6432986B2 (en) * | 1997-07-21 | 2002-08-13 | Bruce H. Levin | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
| US20030185761A1 (en) * | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
| US6143278A (en) * | 1998-02-23 | 2000-11-07 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
| US6090368A (en) * | 1998-03-03 | 2000-07-18 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Pharmaceutical compositions for intranasal spray administration of ketorolac tromethamine |
| EP1137401B1 (de) * | 1998-12-09 | 2005-11-23 | Chiron Corporation | Verabreichung von neurotropischen wirkstoffen in das zentrale nervensystem |
| ATE289800T1 (de) | 1998-12-09 | 2005-03-15 | Chiron Corp | Verwendung eines neurologischen wirkstoffes zur herstellung eines medikamentes zur behandlung von erkrankungen des zentralen nervensystems |
| US7273618B2 (en) * | 1998-12-09 | 2007-09-25 | Chiron Corporation | Method for administering agents to the central nervous system |
| US6139861A (en) * | 1999-01-14 | 2000-10-31 | Friedman; Mark | Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache facial pain, and cervical-muscle spasm |
| KR20020016831A (ko) * | 1999-06-16 | 2002-03-06 | 나스텍 파마수티컬 컴퍼니 인코포레이티드 | 비내용 모르핀을 함유하는 의약 조성물 및 그 제조방법 |
| JP2001002589A (ja) * | 1999-06-18 | 2001-01-09 | Teijin Ltd | 穏やかな薬物血中濃度の上昇を可能とする経鼻投与用組成物 |
| JP2001089359A (ja) * | 1999-09-24 | 2001-04-03 | Toko Yakuhin Kogyo Kk | 鎮痛成分の点鼻用ゲルまたはゾル製剤 |
| WO2001041732A1 (en) * | 1999-12-06 | 2001-06-14 | Gore Stanley L | Compositions and methods for intranasal delivery of active agents to the brain |
| WO2001041782A2 (en) * | 1999-12-09 | 2001-06-14 | Chiron Corporation | Method for administering a cytokine to the central nervous system and the lymphatic system |
| US6413499B1 (en) * | 2000-01-06 | 2002-07-02 | Bryan M. Clay | Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic |
| KR20030060771A (ko) * | 2000-04-28 | 2003-07-16 | 메모리얼 슬로안-케터링 캔서 센터 | 국소용 마취제/아편양약물 제제 및 이들의 용도 |
| US7084126B1 (en) * | 2000-05-01 | 2006-08-01 | Healthpartners Research Foundation | Methods and compositions for enhancing cellular function through protection of tissue components |
| WO2002011778A1 (en) * | 2000-05-10 | 2002-02-14 | University Of Kentucky Research Foundation | System and method for intranasal administration of opioids |
| EP1370282A2 (de) * | 2000-10-13 | 2003-12-17 | Chiron Corporation | Methode zur behandlung ischämischer zustände die das zentrale nervensystem beeinflussen |
| US20070112052A9 (en) * | 2001-01-05 | 2007-05-17 | Larry Caldwell | Methods and compositions for treating headache pain with topical NSAID compositions |
| JP2005500258A (ja) * | 2001-03-23 | 2005-01-06 | アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ | Gm1ガングリオシドを阻害することによる、鎮痛効力を増大し、そして、ニ峰作用性オピオイドアゴニストの有害な興奮性効果を減弱する方法。 |
| US20020169102A1 (en) | 2001-04-03 | 2002-11-14 | Frey William H. | Intranasal delivery of agents for regulating development of implanted cells in the CNS |
| WO2002086105A1 (en) | 2001-04-20 | 2002-10-31 | Chiron Corporation | Delivery of polynucleotide agents to the central nervous sysstem |
| US7820688B2 (en) * | 2001-04-27 | 2010-10-26 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| US20030104085A1 (en) * | 2001-12-05 | 2003-06-05 | Yeomans David C. | Methods and compositions for treating back pain |
| JP2005524649A (ja) * | 2002-02-25 | 2005-08-18 | カイロン コーポレーション | Mc4−rアゴニストの鼻腔内投与 |
| US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US20040105889A1 (en) * | 2002-12-03 | 2004-06-03 | Elan Pharma International Limited | Low viscosity liquid dosage forms |
| WO2003089456A2 (en) * | 2002-04-22 | 2003-10-30 | The Board Of Trustees Of The Leland Stanford Junior University | Peptide inhibitors of protein kinase c |
| EP1504268A2 (de) | 2002-05-02 | 2005-02-09 | Bayer HealthCare AG | Diagnostika und therapeutika für krankheiten, die mit dem oxytocin rezeptor (oxtr) assoziiert sind |
| JP4776229B2 (ja) * | 2002-07-16 | 2011-09-21 | エラン ファーマ インターナショナル,リミティド | 安定なナノ粒子活性物質の液体投与組成物 |
| WO2004019875A2 (en) | 2002-08-30 | 2004-03-11 | Board Of Regents, The University Of Texas System | Non-invasive methods to identify agents for treating pain |
| US7065445B2 (en) * | 2002-11-27 | 2006-06-20 | Mobilearia | Vehicle passive alert system and method |
| WO2004062563A2 (en) | 2003-01-16 | 2004-07-29 | Université de Lausanne | Methods for screening for therapeutic agents that are useful in the treatment of oxytocin and vasopressin-related disorders |
| ATE410170T1 (de) * | 2003-03-27 | 2008-10-15 | Pantarhei Bioscience Bv | Verwendung von estrogenen zur behandlung von männerunfruchtbarkeit |
| KR101184833B1 (ko) | 2003-04-08 | 2012-09-20 | 바이오템프트, 비.브이. | Hcg 절편들을 포함하는 점막 및 경구 투여용 조성물 |
| WO2004093145A2 (en) * | 2003-04-11 | 2004-10-28 | Paratek Microwave, Inc. | Voltage tunable photodefinable dielectric and method of manufacture therefore |
| US20050153885A1 (en) * | 2003-10-08 | 2005-07-14 | Yun Anthony J. | Treatment of conditions through modulation of the autonomic nervous system |
| WO2005115370A2 (en) | 2004-04-23 | 2005-12-08 | The Regents Of The University Of California | Compounds and methods for treating non-inflammatory pain using pparalpha agonists |
| EP1604655A1 (de) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von Trigeminusneuralgie |
| US7618615B2 (en) | 2004-08-13 | 2009-11-17 | Healthpartners Research Foundation | Methods for providing neuroprotection for the animal central nervous system against neurodegeneration caused by ischemia |
| BRPI0608309A2 (pt) * | 2005-02-23 | 2009-12-08 | Alza Corp | administração intranasal de agentes ativos ao sistema nervoso central |
| WO2006099288A2 (en) * | 2005-03-11 | 2006-09-21 | Indevus Pharmaceuticals, Inc. | Controlled release formulations of octreotide |
| US20060252685A1 (en) * | 2005-05-04 | 2006-11-09 | Gould Jeffrey D | Treatment for sleep apnea |
| ATE458491T1 (de) * | 2005-08-26 | 2010-03-15 | Univ Leland Stanford Junior | Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin |
| CN101404174B (zh) * | 2007-10-04 | 2010-06-09 | 威刚科技股份有限公司 | 电子信息储存装置 |
-
2006
- 2006-08-28 AT AT06802456T patent/ATE458491T1/de not_active IP Right Cessation
- 2006-08-28 WO PCT/US2006/033672 patent/WO2007025286A2/en not_active Ceased
- 2006-08-28 EP EP09014456.9A patent/EP2179741B1/de active Active
- 2006-08-28 JP JP2008528234A patent/JP5276982B2/ja active Active
- 2006-08-28 JP JP2008528248A patent/JP2009506076A/ja not_active Withdrawn
- 2006-08-28 US US11/511,569 patent/US20070093420A1/en not_active Abandoned
- 2006-08-28 CA CA2620202A patent/CA2620202C/en active Active
- 2006-08-28 DE DE602006012513T patent/DE602006012513D1/de active Active
- 2006-08-28 CA CA002620364A patent/CA2620364A1/en not_active Abandoned
- 2006-08-28 EP EP06802456A patent/EP1928484B1/de active Active
- 2006-08-28 US US11/990,878 patent/US20090317377A1/en not_active Abandoned
- 2006-08-28 EP EP06813886.6A patent/EP2056800B1/de active Active
- 2006-08-28 US US11/511,997 patent/US20070054843A1/en not_active Abandoned
- 2006-08-28 AU AU2006282799A patent/AU2006282799B2/en active Active
- 2006-08-28 WO PCT/US2006/033500 patent/WO2007025249A2/en not_active Ceased
-
2008
- 2008-02-26 IL IL189777A patent/IL189777A0/en unknown
- 2008-09-15 US US12/210,866 patent/US8198240B2/en active Active
-
2009
- 2009-03-23 US US12/409,413 patent/US20100080797A1/en not_active Abandoned
- 2009-03-23 US US12/409,419 patent/US8202838B2/en active Active
-
2011
- 2011-06-21 US US13/165,646 patent/US8258096B2/en active Active
- 2011-10-07 US US13/269,527 patent/US8252745B2/en active Active
-
2012
- 2012-05-24 US US13/480,291 patent/US8501691B2/en active Active
- 2012-07-26 JP JP2012165636A patent/JP2012207046A/ja not_active Withdrawn
- 2012-12-28 JP JP2012286456A patent/JP5670415B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE458491T1 (de) | Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin | |
| DE602004023829D1 (de) | Verfahren zur behandlung von sinuskopfschmerzen | |
| TW200639166A (en) | Amino-pyridines as inhibitors of β-secretase | |
| WO2011022489A3 (en) | (bis) urea and (bis) thiourea compounds as epigenic modulators of lysine-specific demethylase 1 and methods of treating disorders | |
| ATE464908T1 (de) | Verfahren zur behandlung von osteoarthritis mit anti-il-6 antikörpern | |
| EA201100748A1 (ru) | Пиразиновые соединения в качестве ингибиторов фосфодиэстеразы 10 | |
| EA201000603A1 (ru) | ПРИМЕНЕНИЕ АНТИТЕЛ К TrkB ДЛЯ ЛЕЧЕНИЯ РЕСПИРАТОРНЫХ НАРУШЕНИЙ | |
| DE602004022424D1 (de) | Proteasominhibitoren und verfahren zu deren anwendung | |
| EA200970349A1 (ru) | Ингибиторы металлопротеазы гетероциклического происхождения | |
| EP2054058A4 (de) | Pyruvatkinasehemmer und verfahren zur behandlung von erkrankungen | |
| ATE429645T1 (de) | Verwendung von eph-rezeptor-inhibitoren zur behandlung neurodegenerativer krankheiten | |
| DE602005020580D1 (de) | Stereoisomere verbindungen und verfahren zur behandlung von erkrankungen des magen-darm-trakts und des zentralen nervensystems | |
| EP1595852A4 (de) | Verfahren zur behandlung von ammoniakalischen stickstoffenthaltendem wasser | |
| TW200720272A (en) | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | |
| EA201890884A1 (ru) | Способ и композиции для нежелательных и аномальных мышечных сокращений | |
| EP2046366A4 (de) | Verfahren zur behandlung von altersbedingter makuladegeneration | |
| EA201170698A1 (ru) | Изоляция зон поглощения | |
| EP4408412A4 (de) | Zusammensetzungen und verfahren zur behandlung von kopfschmerzen | |
| EP2037736A4 (de) | Verfahren zur behandlung von zystennierenerkrankungen | |
| NZ759585A (en) | Agent for preventing or treating brain atrophy | |
| ATE408627T1 (de) | Verfahren zur entfernung von fibronektin aus plasmafraktionen | |
| EP3927377A4 (de) | Verfahren zur behandlung von infektionskrankheiten durch targeting des immun-checkpoints von nk-zellen | |
| EA201590884A1 (ru) | Способы лечения заболеваний печени | |
| EP4419690A4 (de) | Zusammensetzungen zur behandlung von cdkl5-mangelstörung (cdd) | |
| ATE445644T1 (de) | Anwendung von molekülen und verfahren zur behandlung von mit mcp-1/ccr2 assoziierten krankheiten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |