ATE454463T1 - Überexpression von extremozymgenen in pseudomonas und nahe verwandte bakterien - Google Patents
Überexpression von extremozymgenen in pseudomonas und nahe verwandte bakterienInfo
- Publication number
- ATE454463T1 ATE454463T1 AT03711011T AT03711011T ATE454463T1 AT E454463 T1 ATE454463 T1 AT E454463T1 AT 03711011 T AT03711011 T AT 03711011T AT 03711011 T AT03711011 T AT 03711011T AT E454463 T1 ATE454463 T1 AT E454463T1
- Authority
- AT
- Austria
- Prior art keywords
- closely related
- extremozym
- overexpression
- pseudomonas
- genes
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title abstract 2
- 230000002018 overexpression Effects 0.000 title abstract 2
- 241000589516 Pseudomonas Species 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2002/004294 WO2003068948A1 (en) | 2002-02-13 | 2002-02-13 | Over-expression of extremozyme genes in pseudomonads and closely related bacteria |
PCT/US2003/004288 WO2003068926A2 (en) | 2002-02-13 | 2003-02-13 | Over-expression of extremozyme genes in pseudomonads and closely related bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE454463T1 true ATE454463T1 (de) | 2010-01-15 |
Family
ID=27732085
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03711011T ATE454463T1 (de) | 2002-02-13 | 2003-02-13 | Überexpression von extremozymgenen in pseudomonas und nahe verwandte bakterien |
Country Status (14)
Country | Link |
---|---|
US (1) | US20050130160A1 (de) |
EP (1) | EP1476562B1 (de) |
JP (1) | JP2006501811A (de) |
CN (1) | CN100451102C (de) |
AT (1) | ATE454463T1 (de) |
AU (2) | AU2002306484A1 (de) |
BR (1) | BR0307630B1 (de) |
CA (1) | CA2475926A1 (de) |
DE (1) | DE60330841D1 (de) |
DK (1) | DK1476562T3 (de) |
MX (1) | MXPA04007886A (de) |
PL (1) | PL372107A1 (de) |
RU (1) | RU2004127236A (de) |
WO (2) | WO2003068948A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100489114C (zh) | 2002-04-22 | 2009-05-20 | 陶氏环球技术公司 | 低成本生产肽 |
US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
BRPI0416744A (pt) * | 2003-11-19 | 2007-01-16 | Dow Global Technologies Inc | sistemas de expressão de proteìna aperfeiçoados |
EP2336153B1 (de) | 2003-11-21 | 2016-03-30 | Pfenex Inc. | Verbessertes Expressionssystem mit SEC-System-Sekretion |
KR101183720B1 (ko) | 2004-01-16 | 2012-09-17 | 다우 글로벌 테크놀로지스 엘엘씨 | 슈도모나스 플루오레센스에서의 포유류 단백질의 발현 |
CA2557668A1 (en) | 2004-02-27 | 2005-09-22 | The Dow Chemical Company | High efficiency peptide production in plant cells |
AU2005269527B2 (en) | 2004-07-26 | 2011-12-01 | Pfenex Inc. | Process for improved protein expression by strain engineering |
US8969033B2 (en) | 2005-11-02 | 2015-03-03 | Battelle Energy Alliance, Llc | Alteration and modulation of protein activity by varying post-translational modification |
US7727755B2 (en) * | 2005-11-02 | 2010-06-01 | Battelle Energy Alliance, Llc | Enzyme and methodology for the treatment of a biomass |
KR101491867B1 (ko) | 2007-01-31 | 2015-02-10 | 피페넥스 인크. | 증가된 발현을 위한 박테리아 리더 서열 |
CA2964910C (en) | 2007-04-27 | 2018-01-09 | Pfenex Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
CN110577945A (zh) | 2007-10-03 | 2019-12-17 | 维莱尼姆公司 | 木聚糖酶、编码它们的核酸以及其制备和应用方法 |
WO2009076196A1 (en) | 2007-12-07 | 2009-06-18 | Dow Global Technologies Inc. | High copy number self-replicating plasmids in pseudomonas |
EP2242841A4 (de) | 2008-01-25 | 2011-05-18 | Battelle Energy Alliance Llc | Wärme- und säurestabile beta-xylosidasen, gene zu ihrer kodierung, entsprechende organismen und verfahren |
US9732330B2 (en) | 2008-01-25 | 2017-08-15 | Battelle Energy Alliance, Llc | Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes |
US8492114B2 (en) | 2008-01-25 | 2013-07-23 | Battelle Energy Alliance, Llc | Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes |
US8497110B2 (en) | 2008-01-31 | 2013-07-30 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods |
EP2235174A4 (de) | 2008-01-31 | 2012-05-09 | Battelle Energy Alliance Llc | Thermophile und thermoacidophile biopolymerabbaugene, enzyme aus alicyclobacillus acidocaldarius sowie entsprechende organismen und verfahren |
US8557557B2 (en) | 2008-01-31 | 2013-10-15 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods |
US8426185B2 (en) | 2008-01-31 | 2013-04-23 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods |
BRPI0907407A2 (pt) | 2008-02-22 | 2019-09-24 | Battelle Energy Alliance Llc | controle transcricional em alicyclobacillus acidocaldarius e genes, proteínas e métodos associados |
MX2010008246A (es) | 2008-02-26 | 2010-11-12 | Battelle Energy Alliance Llc | Genes transportadores de azucar termofilicos y termoacidofilicos y enzimas de alicyclobacillus acidocaldarius y organismos relacionados, metodos. |
CN102046802A (zh) | 2008-02-27 | 2011-05-04 | 巴特勒能源同盟有限公司 | 来自酸热脂环酸杆菌的嗜热的与嗜热嗜酸的糖基化基因和酶以及相关生物、方法 |
WO2009145945A2 (en) | 2008-02-28 | 2009-12-03 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldarius and related organisms |
CN101613681B (zh) * | 2008-06-24 | 2013-07-10 | 中国科学院上海生命科学研究院 | 重组极端耐热α-淀粉酶的复性与纯化方法 |
US8357503B2 (en) | 2008-08-29 | 2013-01-22 | Bunge Oils, Inc. | Hydrolases, nucleic acids encoding them and methods for making and using them |
US8198062B2 (en) * | 2008-08-29 | 2012-06-12 | Dsm Ip Assets B.V. | Hydrolases, nucleic acids encoding them and methods for making and using them |
US8153391B2 (en) | 2008-08-29 | 2012-04-10 | Bunge Oils, Inc. | Hydrolases, nucleic acids encoding them and methods for making and using them |
EP2430170A4 (de) * | 2009-05-15 | 2012-12-05 | Univ Florida | Erhöhte expression von transhydrogenasegenen und ihre verwendung in der ethanolherstellung |
UA109884C2 (uk) | 2009-10-16 | 2015-10-26 | Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування | |
UA111708C2 (uk) | 2009-10-16 | 2016-06-10 | Бандж Ойлз, Інк. | Спосіб рафінування олії |
US20110275135A1 (en) | 2010-05-05 | 2011-11-10 | Battelle Energy Alliance, Llc | Genetic elements, proteins, and associated methods including application of additional genetic information to gram (+) thermoacidophiles |
CN110511946A (zh) | 2012-03-30 | 2019-11-29 | 巴斯夫爱酶孜有限公司 | 编码纤维素酶的基因 |
GB201308828D0 (en) | 2013-03-12 | 2013-07-03 | Verenium Corp | Phytase |
GB201308853D0 (en) | 2013-03-12 | 2013-07-03 | Verenium Corp | Genes encoding xylanase |
GB201308843D0 (en) | 2013-03-14 | 2013-07-03 | Verenium Corp | Phytase formulation |
TW201504259A (zh) | 2013-07-25 | 2015-02-01 | Verenium Corp | 植酸酶 |
CA3075879A1 (en) | 2017-09-26 | 2019-04-04 | Bunge Global Innovation, Llc. | Enzymatic removal of chlorophyll substrates from triacylglycerol-based oils |
CA3127018A1 (en) | 2019-03-27 | 2020-10-01 | Bunge Global Innovation, Llc | Silica adsorbent treatment for removal of chlorophyll derivatives from triacylglycerol-based oils |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4551433A (en) | 1981-05-18 | 1985-11-05 | Genentech, Inc. | Microbial hybrid promoters |
US4755465A (en) | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
US4680264A (en) | 1983-07-01 | 1987-07-14 | Lubrizol Genetics, Inc. | Class II mobilizable gram-negative plasmid |
US5281532A (en) | 1983-07-27 | 1994-01-25 | Mycogen Corporation | Pseudomas hosts transformed with bacillus endotoxin genes |
US4753876A (en) | 1984-03-21 | 1988-06-28 | Monsanto Company | Marker genes in pseudomonad bacteria |
US4695462A (en) | 1985-06-28 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of biological pesticides |
US4695455A (en) | 1985-01-22 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of pesticides produced by expression of heterologous genes |
US5028530A (en) | 1985-01-28 | 1991-07-02 | Xoma Corporation | AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques |
US5232840A (en) * | 1986-03-27 | 1993-08-03 | Monsanto Company | Enhanced protein production in bacteria by employing a novel ribosome binding site |
US5079352A (en) * | 1986-08-22 | 1992-01-07 | Cetus Corporation | Purified thermostable enzyme |
US5128130A (en) | 1988-01-22 | 1992-07-07 | Mycogen Corporation | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens |
US5055294A (en) | 1988-03-03 | 1991-10-08 | Mycogen Corporation | Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens |
US6168945B1 (en) * | 1988-03-23 | 2001-01-02 | The Board Of Regents Of The University Of Oklahoma | Genes encoding operon and promoter for branched chain keto acid dehydrogenase of pseudomonas putida and methods |
US5169760A (en) | 1989-07-27 | 1992-12-08 | Mycogen Corporation | Method, vectors, and host cells for the control of expression of heterologous genes from lac operated promoters |
US5210025A (en) | 1990-03-30 | 1993-05-11 | University Of Alaska | Prepressor protein gene for regulating expression of polypeptides and its use in the preparation of 2,2-dialkylglycine decarboxylase of Pseudomonas cepacia |
US5356796A (en) | 1990-03-30 | 1994-10-18 | The University Of Alaska | Repressor protein and operon for regulating expression of polypeptides and its use in the preparation of 2,2-dialkyglycine decarboxylase of Pseudomonas cepacia |
US5670350A (en) | 1990-08-20 | 1997-09-23 | Novartis Finance Corporation | Genomic DNA encoding a pseudomonas global transcriptional activation element and its use in activating gene expression |
JPH074256B2 (ja) * | 1990-10-31 | 1995-01-25 | 栗田工業株式会社 | リパーゼの活性発現を調節する遺伝子、ベクターおよびリパーゼの生産方法 |
US5578479A (en) | 1992-06-09 | 1996-11-26 | The Johns Hopkins University | Alpha-amylase from hyperthermophilic archaebacterium |
US5366883A (en) | 1992-06-09 | 1994-11-22 | Takara Shuzo Co., Ltd. | α-amylase gene |
EP0648843A1 (de) | 1993-10-01 | 1995-04-19 | Takara Shuzo Co. Ltd. | Für ein hyperthermostabiles Alpha-amylase kodierendes DNA |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
US5527883A (en) * | 1994-05-06 | 1996-06-18 | Mycogen Corporation | Delta-endotoxin expression in pseudomonas fluorescens |
GB2291058B (en) | 1994-07-14 | 1998-12-23 | Solvay | Acid-stable and thermo-stable alpha-amylases derived from sufolobus species |
US5958672A (en) | 1995-07-18 | 1999-09-28 | Diversa Corporation | Protein activity screening of clones having DNA from uncultivated microorganisms |
US6057103A (en) | 1995-07-18 | 2000-05-02 | Diversa Corporation | Screening for novel bioactivities |
US6171820B1 (en) | 1995-12-07 | 2001-01-09 | Diversa Corporation | Saturation mutagenesis in directed evolution |
US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
US5830696A (en) | 1996-12-05 | 1998-11-03 | Diversa Corporation | Directed evolution of thermophilic enzymes |
US6153410A (en) | 1997-03-25 | 2000-11-28 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
AU7107798A (en) | 1997-04-09 | 1998-10-30 | Michigan State University | Hyperthermostable alpha-amylase |
US20040091968A1 (en) * | 1997-08-13 | 2004-05-13 | Short Jay M. | Recombinant phytases and methods of making and using them |
US6261842B1 (en) | 1997-10-23 | 2001-07-17 | Wisconsin Alumni Research Foundation | Microorganism genomics, compositions and methods related thereto |
US6090593A (en) | 1998-05-13 | 2000-07-18 | The United States Of America As Represented By The Secretary Of The Air Force | Isolation of expressed genes in microorganisms |
KR100312456B1 (ko) * | 1999-03-13 | 2001-11-03 | 윤덕용 | 슈도모나스 플루오레슨스 유래의 외래단백질 분비촉진유전자 |
JP2000350585A (ja) * | 1999-06-10 | 2000-12-19 | Tokyo Gas Co Ltd | 耐熱耐酸素性ヒドロゲナーゼ遺伝子 |
CA2360750A1 (en) * | 1999-11-22 | 2001-05-31 | Diversa Corporation | Capillary array-based sample screening |
US20010047029A1 (en) | 2000-04-26 | 2001-11-29 | Handelsman Jo E. | Triaryl cation antibiotics from environmental DNA |
US9453251B2 (en) * | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
-
2002
- 2002-02-13 WO PCT/US2002/004294 patent/WO2003068948A1/en not_active Application Discontinuation
- 2002-02-13 MX MXPA04007886A patent/MXPA04007886A/es active IP Right Grant
- 2002-02-13 AU AU2002306484A patent/AU2002306484A1/en not_active Abandoned
-
2003
- 2003-02-13 AU AU2003215197A patent/AU2003215197B2/en not_active Expired
- 2003-02-13 WO PCT/US2003/004288 patent/WO2003068926A2/en active Application Filing
- 2003-02-13 CA CA002475926A patent/CA2475926A1/en not_active Abandoned
- 2003-02-13 US US10/504,505 patent/US20050130160A1/en not_active Abandoned
- 2003-02-13 JP JP2003568041A patent/JP2006501811A/ja active Pending
- 2003-02-13 DK DK03711011.1T patent/DK1476562T3/da active
- 2003-02-13 BR BRPI0307630-0A patent/BR0307630B1/pt active IP Right Grant
- 2003-02-13 PL PL03372107A patent/PL372107A1/xx unknown
- 2003-02-13 EP EP03711011A patent/EP1476562B1/de not_active Expired - Lifetime
- 2003-02-13 RU RU2004127236/13A patent/RU2004127236A/ru not_active Application Discontinuation
- 2003-02-13 DE DE60330841T patent/DE60330841D1/de not_active Expired - Lifetime
- 2003-02-13 CN CNB038082403A patent/CN100451102C/zh not_active Expired - Lifetime
- 2003-02-13 AT AT03711011T patent/ATE454463T1/de active
Also Published As
Publication number | Publication date |
---|---|
BR0307630A (pt) | 2005-01-11 |
RU2004127236A (ru) | 2005-04-20 |
PL372107A1 (en) | 2005-07-11 |
JP2006501811A (ja) | 2006-01-19 |
AU2003215197A1 (en) | 2003-09-04 |
EP1476562B1 (de) | 2010-01-06 |
EP1476562A4 (de) | 2005-12-07 |
US20050130160A1 (en) | 2005-06-16 |
CA2475926A1 (en) | 2003-08-21 |
DE60330841D1 (de) | 2010-02-25 |
WO2003068948A1 (en) | 2003-08-21 |
WO2003068926A2 (en) | 2003-08-21 |
MXPA04007886A (es) | 2004-10-15 |
CN1646694A (zh) | 2005-07-27 |
CN100451102C (zh) | 2009-01-14 |
EP1476562A2 (de) | 2004-11-17 |
DK1476562T3 (da) | 2010-04-19 |
WO2003068926A3 (en) | 2004-02-26 |
BR0307630B1 (pt) | 2014-08-19 |
AU2002306484A1 (en) | 2003-09-04 |
AU2003215197B2 (en) | 2008-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE454463T1 (de) | Überexpression von extremozymgenen in pseudomonas und nahe verwandte bakterien | |
BR0210839A (pt) | Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico | |
EP2339017A3 (de) | Erhöhte Proteinexpression in Bacillus | |
WO2003012058A3 (en) | Media and methods for cultivation of microorganisms | |
EP2287178A3 (de) | Bacillus licheniformis YvmC-Deaktivierung | |
PL2426220T3 (pl) | Wyznakowane mikroorganizmy i sposoby wyznakowania | |
DK0698105T3 (da) | Nukleotidsekvenser til styring af ekspressionen af DNAsekvenser i en værtscelle | |
DE69942459D1 (de) | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung | |
WO2004063362A3 (en) | Cell cycle progression proteins | |
NO985376L (no) | Kinolinkarboksamider som TNF-inhibitorer og som PDA-IV inhibitorer | |
WO2003104418A3 (en) | RECONSTITUTED POLYPEPTIDES | |
IL190796A (en) | Composition containing nucleic acid encoded by anti-osteoclastogenic protein | |
ATE407138T1 (de) | Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle | |
MX2007010045A (es) | Pirazolopirimidinas. | |
DE60325611D1 (de) | Benzoat- und antranilatinduzierbare promotoren | |
NZ242124A (en) | Dna encoding an enzyme having arabinan-degrading activity | |
DE69928395D1 (de) | Cyclin-e2 proteine und dafür kodierende gene | |
DE69732857D1 (de) | Nukleinsaeuren und proteine der katze fc-epsilon rezeptor alpha-kette und deren verwendungen | |
CY1105778T1 (el) | Γονιδιο του streptomyces avermitilis που κατευθυνει την αναλογια των αβepμεκτινων β2:β1 | |
IT1317849B1 (it) | Mezzi e metodi per l'espressione di proteine omologhe ed eterologhe inceppi di rhodococcus. | |
WO2006033668A3 (en) | Pcka modifications and enhanced protein expression in bacillus | |
DE60130465D1 (de) | Mutierte muskelspezifische enhancer | |
BR0311485A (pt) | Método para flocular uma célula de bacillus e/ou remover contaminantes de peso molecular alto | |
Ramaiah et al. | Enzymatic reaction with unnatural substrates: DNA photolyase (Escherichia coli) recognizes and reverses thymine [2+ 2] dimers in the DNA strand of a DNA/PNA hybrid duplex | |
ATE334209T1 (de) | Inaktivierung von genen des mep-wegs |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1476562 Country of ref document: EP |