ATE45357T1 - Theophyllin-7-essigsaurer ester von d,l-transsobrerol mit mucosecretolyt-fluidisierender und antibronchospastischer wirkung, ein verfahren zu seiner herstellung und pharmazeutische praeparate. - Google Patents
Theophyllin-7-essigsaurer ester von d,l-transsobrerol mit mucosecretolyt-fluidisierender und antibronchospastischer wirkung, ein verfahren zu seiner herstellung und pharmazeutische praeparate.Info
- Publication number
- ATE45357T1 ATE45357T1 AT85103178T AT85103178T ATE45357T1 AT E45357 T1 ATE45357 T1 AT E45357T1 AT 85103178 T AT85103178 T AT 85103178T AT 85103178 T AT85103178 T AT 85103178T AT E45357 T1 ATE45357 T1 AT E45357T1
- Authority
- AT
- Austria
- Prior art keywords
- theophylline
- fluidizing
- antibronchospastic
- transsobrerol
- mucosecretolyte
- Prior art date
Links
- 230000002562 anti-bronchospastic effect Effects 0.000 title abstract 2
- OMDMTHRBGUBUCO-BDAKNGLRSA-N (1s,5r)-5-(2-hydroxypropan-2-yl)-2-methylcyclohex-2-en-1-ol Chemical compound CC1=CC[C@@H](C(C)(C)O)C[C@@H]1O OMDMTHRBGUBUCO-BDAKNGLRSA-N 0.000 title 1
- HCYFGRCYSCXKNQ-UHFFFAOYSA-M 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetate Chemical compound O=C1N(C)C(=O)N(C)C2=C1N(CC([O-])=O)C=N2 HCYFGRCYSCXKNQ-UHFFFAOYSA-M 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- HCYFGRCYSCXKNQ-UHFFFAOYSA-N 2-(1,3-dimethyl-2,6-dioxo-7-purinyl)acetic acid Chemical compound O=C1N(C)C(=O)N(C)C2=C1N(CC(O)=O)C=N2 HCYFGRCYSCXKNQ-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20353/84A IT1173549B (it) | 1984-04-02 | 1984-04-02 | Estere dell'acido teofillin-7-acetico con il d,l-trans-sobrerolo avente attivita' mucosecretolitica-fluidificante e antibroncospastica, procedimento per la sua preparazione e sue composizioni farmaceutiche |
| EP85103178A EP0157284B1 (de) | 1984-04-02 | 1985-03-19 | Theophyllin-7-essigsaurer Ester von D,L-Trans-Sobrerol mit Mucosecretolyt-fluidisierender und antibronchospastischer Wirkung, ein Verfahren zu seiner Herstellung und pharmazeutische Präparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE45357T1 true ATE45357T1 (de) | 1989-08-15 |
Family
ID=11165967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85103178T ATE45357T1 (de) | 1984-04-02 | 1985-03-19 | Theophyllin-7-essigsaurer ester von d,l-transsobrerol mit mucosecretolyt-fluidisierender und antibronchospastischer wirkung, ein verfahren zu seiner herstellung und pharmazeutische praeparate. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4652568A (de) |
| EP (1) | EP0157284B1 (de) |
| JP (1) | JPS60224690A (de) |
| KR (1) | KR910004428B1 (de) |
| AT (1) | ATE45357T1 (de) |
| DE (1) | DE3572171D1 (de) |
| IT (1) | IT1173549B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2183562A1 (en) * | 1994-02-18 | 1995-08-24 | J. Peter Klein | Intracellular signalling mediators |
| ES2310047T3 (es) * | 1998-08-18 | 2008-12-16 | The Regents Of The University Of California | Antagonistas del receptor del factor de crecimiento epidermico para el tratamiento de la hipersecrecion de mucosidad en los pulmones. |
| US6814743B2 (en) * | 2001-12-26 | 2004-11-09 | Origin Medsystems, Inc. | Temporary seal and method for facilitating anastomosis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2756229A (en) * | 1956-07-24 | Xanthine derivatives | ||
| DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
| FR2101120B1 (de) * | 1970-08-25 | 1974-05-24 | Socibre | |
| US4120947A (en) * | 1976-03-31 | 1978-10-17 | Cooper Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
| FR2393803A1 (fr) * | 1977-06-06 | 1979-01-05 | Abc Ist Biolog Chem Spa | Theophylline-7-acetate de 2-(p-chlorophenoxy)-2 methylpropyle, utile notamment comme hypocholesterolemiant, et son procede de preparation |
-
1984
- 1984-04-02 IT IT20353/84A patent/IT1173549B/it active
-
1985
- 1985-03-14 US US06/711,665 patent/US4652568A/en not_active Expired - Fee Related
- 1985-03-19 AT AT85103178T patent/ATE45357T1/de not_active IP Right Cessation
- 1985-03-19 EP EP85103178A patent/EP0157284B1/de not_active Expired
- 1985-03-19 DE DE8585103178T patent/DE3572171D1/de not_active Expired
- 1985-04-01 JP JP60066708A patent/JPS60224690A/ja active Pending
- 1985-04-01 KR KR1019850002181A patent/KR910004428B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR850007253A (ko) | 1985-12-02 |
| EP0157284A2 (de) | 1985-10-09 |
| DE3572171D1 (en) | 1989-09-14 |
| EP0157284A3 (en) | 1986-10-08 |
| KR910004428B1 (ko) | 1991-06-27 |
| IT8420353A0 (it) | 1984-04-02 |
| JPS60224690A (ja) | 1985-11-09 |
| US4652568A (en) | 1987-03-24 |
| EP0157284B1 (de) | 1989-08-09 |
| IT1173549B (it) | 1987-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee | ||
| UEP | Publication of translation of european patent specification |