ATE452892T1 - Substituierte 8-perfluoro-6,7,8,9- tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate - Google Patents

Substituierte 8-perfluoro-6,7,8,9- tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate

Info

Publication number: ATE452892T1
Authority: AT; Austria
Prior art keywords: tetrahydropyrimido; perfluoro; pyrimidin; derivatives; substituted
Prior art date: 2003-03-21

Application number

AT04721906T

Other languages

English (en)

Inventor

Alistair Lochead

Mourad Saady

Franck Slowinski

Philippe Yaiche

Original Assignee

Sanofi Aventis

Mitsubishi Tanabe Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-21

Filing date

2004-03-19

Publication date

2010-01-15

2004-03-19 Application filed by Sanofi Aventis, Mitsubishi Tanabe Pharma Corp filed Critical Sanofi Aventis

2010-01-15 Application granted granted Critical

2010-01-15 Publication of ATE452892T1 publication Critical patent/ATE452892T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT04721906T 2003-03-21 2004-03-19 Substituierte 8-perfluoro-6,7,8,9- tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate ATE452892T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03290727A EP1460075A1 (de)	2003-03-21	2003-03-21	Substituierte 8-Perfluoro-6,7,8,9-tetrahydropyrimido[1,2a] pyrimidin-4-on Derivate
PCT/EP2004/004014 WO2004082577A2 (en)	2003-03-21	2004-03-19	8-SUBSTITUTED-6, 7, 8, 9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE DERIVATIVES

Publications (1)

Publication Number	Publication Date
ATE452892T1 true ATE452892T1 (de)	2010-01-15

Family

ID=32799140

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04721906T ATE452892T1 (de)	2003-03-21	2004-03-19	Substituierte 8-perfluoro-6,7,8,9- tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate

Country Status (26)

Country	Link
US (2)	US7247638B2 (de)
EP (2)	EP1460075A1 (de)
JP (1)	JP4572195B2 (de)
KR (1)	KR101070149B1 (de)
CN (1)	CN100358897C (de)
AR (1)	AR043658A1 (de)
AT (1)	ATE452892T1 (de)
AU (1)	AU2004222596B2 (de)
BR (1)	BRPI0408591A (de)
CA (1)	CA2518299C (de)
CY (1)	CY1109890T1 (de)
DE (1)	DE602004024770D1 (de)
DK (1)	DK1608654T3 (de)
EA (1)	EA009197B1 (de)
ES (1)	ES2338325T3 (de)
HK (1)	HK1086012A1 (de)
IL (1)	IL170680A (de)
MX (1)	MXPA05010158A (de)
NO (1)	NO20054330L (de)
NZ (1)	NZ542380A (de)
PL (1)	PL1608654T3 (de)
PT (1)	PT1608654E (de)
SI (1)	SI1608654T1 (de)
TW (1)	TWI330186B (de)
WO (1)	WO2004082577A2 (de)
ZA (1)	ZA200507487B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1460075A1 (de) *	2003-03-21	2004-09-22	Sanofi-Synthelabo	Substituierte 8-Perfluoro-6,7,8,9-tetrahydropyrimido[1,2a] pyrimidin-4-on Derivate
MX2009001043A (es)	2006-08-08	2009-02-06	Sanofi Aventis	Imidazolidina-2,4-dionas sustituidas con arilaminoarilalquilo, procedimiento para preparalas, medicamentos que comprenden estos compuestos y su uso.
EP1939187A1 (de) *	2006-12-20	2008-07-02	Sanofi-Aventis	Substituierte Heteroaryl-Pyridopyrimidon-Derivate
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US8470841B2 (en)	2008-07-09	2013-06-25	Sanofi	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
MX2012001729A (es)	2009-08-26	2012-06-13	Sanofi Sa	Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de)	2010-06-18	2011-12-22	Sanofi	Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2012120050A1 (de)	2011-03-08	2012-09-13	Sanofi	Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683704B1 (de)	2011-03-08	2014-12-17	Sanofi	Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de)	2011-03-08	2015-06-24	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120054A1 (de)	2011-03-08	2012-09-13	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en)	2011-03-08	2014-09-30	Sanofi	Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683700B1 (de)	2011-03-08	2015-02-18	Sanofi	Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120052A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683698B1 (de)	2011-03-08	2017-10-04	Sanofi	Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de)	2011-03-08	2015-05-27	Sanofi	Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
AU2020353055B2 (en)	2019-09-26	2024-03-07	Gilead Sciences, Inc.	Antiviral pyrazolopyridinone compounds

Family Cites Families (5)

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Publication number	Priority date	Publication date	Assignee	Title
JP2001270884A (ja) *	2000-03-23	2001-10-02	Mitsubishi-Tokyo Pharmaceuticals Inc	ピリミドン誘導体
EP1136482A1 (de) *	2000-03-23	2001-09-26	Sanofi-Synthelabo	2-Amino-3-(alkyl)-pyrimidonderivate als GSK3beta-Hemmer
AU2002212249B9 (en) *	2000-09-01	2007-01-18	Mitsubishi Pharma Corporation	2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives
EP1184383A1 (de) *	2000-09-01	2002-03-06	Sanofi-Synthelabo	9-[Alkyl], 9-[(Heteroaryl)alkyl] und 9-[(Aryl)alkyl]-2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-on Derivate
EP1460075A1 (de) *	2003-03-21	2004-09-22	Sanofi-Synthelabo	Substituierte 8-Perfluoro-6,7,8,9-tetrahydropyrimido[1,2a] pyrimidin-4-on Derivate

2003
- 2003-03-21 EP EP03290727A patent/EP1460075A1/de not_active Withdrawn
2004
- 2004-03-17 TW TW093107079A patent/TWI330186B/zh not_active IP Right Cessation
- 2004-03-19 CA CA2518299A patent/CA2518299C/en not_active Expired - Fee Related
- 2004-03-19 BR BRPI0408591-4A patent/BRPI0408591A/pt not_active IP Right Cessation
- 2004-03-19 DE DE602004024770T patent/DE602004024770D1/de not_active Expired - Lifetime
- 2004-03-19 AT AT04721906T patent/ATE452892T1/de active
- 2004-03-19 SI SI200431367T patent/SI1608654T1/sl unknown
- 2004-03-19 EP EP04721906A patent/EP1608654B1/de not_active Expired - Lifetime
- 2004-03-19 PL PL04721906T patent/PL1608654T3/pl unknown
- 2004-03-19 AU AU2004222596A patent/AU2004222596B2/en not_active Ceased
- 2004-03-19 CN CNB2004800120116A patent/CN100358897C/zh not_active Expired - Fee Related
- 2004-03-19 KR KR1020057017572A patent/KR101070149B1/ko not_active IP Right Cessation
- 2004-03-19 NZ NZ542380A patent/NZ542380A/en not_active IP Right Cessation
- 2004-03-19 EA EA200501315A patent/EA009197B1/ru not_active IP Right Cessation
- 2004-03-19 DK DK04721906.8T patent/DK1608654T3/da active
- 2004-03-19 ZA ZA200507487A patent/ZA200507487B/en unknown
- 2004-03-19 JP JP2006505152A patent/JP4572195B2/ja not_active Expired - Fee Related
- 2004-03-19 MX MXPA05010158A patent/MXPA05010158A/es active IP Right Grant
- 2004-03-19 WO PCT/EP2004/004014 patent/WO2004082577A2/en active Application Filing
- 2004-03-19 PT PT04721906T patent/PT1608654E/pt unknown
- 2004-03-19 ES ES04721906T patent/ES2338325T3/es not_active Expired - Lifetime
- 2004-03-19 AR ARP040100917A patent/AR043658A1/es unknown
2005
- 2005-09-05 IL IL170680A patent/IL170680A/en not_active IP Right Cessation
- 2005-09-13 US US11/225,218 patent/US7247638B2/en not_active Expired - Fee Related
- 2005-09-20 NO NO20054330A patent/NO20054330L/no not_active Application Discontinuation
2006
- 2006-06-24 HK HK06108336A patent/HK1086012A1/xx not_active IP Right Cessation
2007
- 2007-06-18 US US11/764,374 patent/US8093256B2/en not_active Expired - Fee Related
2010
- 2010-03-09 CY CY20101100221T patent/CY1109890T1/el unknown

Also Published As

Publication number	Publication date
DK1608654T3 (da)	2010-04-26
EA200501315A1 (ru)	2006-04-28
WO2004082577A2 (en)	2004-09-30
CN100358897C (zh)	2008-01-02
AU2004222596B2 (en)	2008-08-28
US7247638B2 (en)	2007-07-24
EP1460075A1 (de)	2004-09-22
IL170680A0 (en)	2009-02-11
US8093256B2 (en)	2012-01-10
EP1608654B1 (de)	2009-12-23
BRPI0408591A (pt)	2006-03-21
TWI330186B (en)	2010-09-11
WO2004082577A3 (en)	2004-11-04
ES2338325T3 (es)	2010-05-06
US20080021046A1 (en)	2008-01-24
NZ542380A (en)	2009-01-31
KR20050111782A (ko)	2005-11-28
EP1608654A2 (de)	2005-12-28
NO20054330D0 (no)	2005-09-20
DE602004024770D1 (de)	2010-02-04
NO20054330L (no)	2005-12-21
JP4572195B2 (ja)	2010-10-27
ZA200507487B (en)	2006-12-27
CA2518299C (en)	2011-10-25
AR043658A1 (es)	2005-08-03
MXPA05010158A (es)	2006-05-19
PL1608654T3 (pl)	2010-07-30
CY1109890T1 (el)	2014-09-10
AU2004222596A1 (en)	2004-09-30
TW200504070A (en)	2005-02-01
KR101070149B1 (ko)	2011-10-05
HK1086012A1 (en)	2006-09-08
PT1608654E (pt)	2010-03-05
US20060035885A1 (en)	2006-02-16
SI1608654T1 (sl)	2010-04-30
CA2518299A1 (en)	2004-09-30
JP2006520767A (ja)	2006-09-14
EA009197B1 (ru)	2007-12-28
IL170680A (en)	2012-10-31
CN1784408A (zh)	2006-06-07

Publication	Publication Date	Title
ATE452892T1 (de)	2010-01-15	Substituierte 8-perfluoro-6,7,8,9- tetrahydropyrimido-(1,2a) pyrimidin-4-on derivate
ATE360632T1 (de)	2007-05-15	Substituierte 8'-pyri(mi)dinyl-dihydrospiro- (cycloalkylamin)-pyrimido(1,2a)pyrimidin-6- onderivate
DE60225563D1 (de)	2008-04-24	4-amino-6-phenyl-pyrroloä2,3-düpyrimidin derivate
DE60216115D1 (de)	2006-12-28	BENZIMIDAZO 4,5-föISOCHINOLINON-DERIVATE
ATE512965T1 (de)	2011-07-15	Pyrrolopyrimidin derivate
DK1594840T3 (da)	2007-02-05	Piperidin-benzensulfonamid-derivater
ATE370120T1 (de)	2007-09-15	Substituierte 2-pyridin-cyclohexan-1,4- diaminderivate
HK1088893A1 (en)	2006-11-17	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimidoÄ1,2-aÜ pyrimidin-4-one derivatives
ATE478870T1 (de)	2010-09-15	Spiroindolinpiperidinderivate
ATE460418T1 (de)	2010-03-15	Heterocyclocarboxamidderivate
ATE450506T1 (de)	2009-12-15	Indol-3-schwefelderivate
ATE467631T1 (de)	2010-05-15	Chinuclidinamidderivate
ATE438644T1 (de)	2009-08-15	Chinazolinderivate
ATE420066T1 (de)	2009-01-15	Amidoacetonitrilderivate
ATE352550T1 (de)	2007-02-15	Chinazolinderivate
NO20053748D0 (no)	2005-08-04	Pyrrolopyridazinderivater.
ATE395345T1 (de)	2008-05-15	Imidazol-4-yl-ethynyl-pyridin-derivate
IS8364A (is)	2006-03-20	N-þíasól-2-ýl-bensamíð afleiður
IS8180A (is)	2005-12-14	Nýjar besímídasólafleiður
ATE326467T1 (de)	2006-06-15	Imidazo 1,2-aöpyridine
ATE335729T1 (de)	2006-09-15	3h-chinazoline -4-on derivaten
ATE423771T1 (de)	2009-03-15	Tetrahydrochinolinderivate
ATE449064T1 (de)	2009-12-15	Amidoacetonitrilderivate
IS8045A (is)	2005-09-26	Púrín-6-ón-afleiður
DE50306277D1 (de)	2007-02-22	4-alkyl-/4-alkenyl-/4-alkinylmethyl/-1-arylcyclohexylamin-derivate

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