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ATE44825T1 - Mehrparameterteilchen-analysierverfahren unter verwendung der fluoreszenzmessung. - Google Patents

Mehrparameterteilchen-analysierverfahren unter verwendung der fluoreszenzmessung.

Info

Publication number
ATE44825T1
ATE44825T1 AT84302306T AT84302306T ATE44825T1 AT E44825 T1 ATE44825 T1 AT E44825T1 AT 84302306 T AT84302306 T AT 84302306T AT 84302306 T AT84302306 T AT 84302306T AT E44825 T1 ATE44825 T1 AT E44825T1
Authority
AT
Austria
Prior art keywords
multiparameter
fluorescence measurement
particle analyzing
analyzing methods
methods
Prior art date
Application number
AT84302306T
Other languages
English (en)
Inventor
Edwin F Ullman
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE44825T1 publication Critical patent/ATE44825T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT84302306T 1983-04-05 1984-04-04 Mehrparameterteilchen-analysierverfahren unter verwendung der fluoreszenzmessung. ATE44825T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/482,124 US4584277A (en) 1983-04-05 1983-04-05 Fluorescent multiparameter particle analysis
EP84302306A EP0121442B1 (de) 1983-04-05 1984-04-04 Mehrparameterteilchen-Analysierverfahren unter Verwendung der Fluoreszenzmessung

Publications (1)

Publication Number Publication Date
ATE44825T1 true ATE44825T1 (de) 1989-08-15

Family

ID=23914787

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84302306T ATE44825T1 (de) 1983-04-05 1984-04-04 Mehrparameterteilchen-analysierverfahren unter verwendung der fluoreszenzmessung.

Country Status (6)

Country Link
US (1) US4584277A (de)
EP (1) EP0121442B1 (de)
JP (1) JPS59195160A (de)
AT (1) ATE44825T1 (de)
CA (1) CA1225589A (de)
DE (1) DE3479057D1 (de)

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DE3238353A1 (de) * 1982-10-15 1984-04-19 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer
DE3811097A1 (de) * 1988-03-31 1989-10-12 Orpegen Med Molekularbioforsch Verfahren zur steuerung biologischer klaerstufen
US5071774A (en) * 1983-04-05 1991-12-10 Syntex (U.S.A.) Inc. Multiparameter particle analysis
US4748129A (en) * 1984-08-28 1988-05-31 Snytex (U.S.A.) Inc. Assay method employing fluorescent cell incorporative dye
EP0184600B1 (de) * 1984-12-10 1990-03-14 Prutec Limited Verfahren zum optischen Nachweis von Parametern von Substanzen in einem flüssigen Analyt
US4996143A (en) * 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5569587A (en) * 1986-04-18 1996-10-29 Carnegie Mellon University Method for labeling and detecting materials employing luminescent arysulfonate cyanine dyes
US5627027A (en) * 1986-04-18 1997-05-06 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
CA1326435C (en) * 1987-03-13 1994-01-25 Wallace H. Coulter Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
US5238812A (en) * 1987-03-13 1993-08-24 Coulter Corporation Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
US4837162A (en) * 1987-06-05 1989-06-06 Pall Corporation Non-fluorescing, non-reflective polyamide for use in diagnostic testing
SE458968B (sv) * 1987-06-16 1989-05-22 Wallac Oy Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser
SE8800613D0 (sv) * 1988-02-23 1988-02-23 Wallac Oy A novel spectrofluorometric method and compounds that are of value for the method
JP2766677B2 (ja) * 1988-06-23 1998-06-18 ベーリンクベルケ アクチエンゲゼルシャフト 多重パラメーター粒子分析
FI82144C (fi) * 1989-03-22 1991-01-10 Wallac Oy Foerfarande foer samtidig bestaemning av flera ligander.
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US6955915B2 (en) * 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US6919211B1 (en) 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
CA2021658C (en) * 1989-08-25 2001-10-09 Myron J. Block Multiplex immunoassay system
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
DE69132843T2 (de) 1990-12-06 2002-09-12 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Identifizierung von Nukleinsäuren in Proben
DE69227112D1 (de) * 1991-07-16 1998-10-29 Transmed Biotech Inc Verfahren und zusammensetzungen für die gleichzeitige analyse einer vielzahl von analyten
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
ATE241426T1 (de) * 1991-11-22 2003-06-15 Affymetrix Inc A Delaware Corp Verfahren zur herstellung von polymerarrays
US6864101B1 (en) 1991-11-22 2005-03-08 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
US6593148B1 (en) 1994-03-01 2003-07-15 Li-Cor, Inc. Cyanine dye compounds and labeling methods
US6040197A (en) * 1994-05-17 2000-03-21 Spallholz; Julian E. Method for the preparation of free radical pharmaceuticals, diagnostics and devices using selenium conjugates
US5783454A (en) * 1994-05-17 1998-07-21 Spallholz; Julian E. Method for the preparation of free radical pharmaceuticals using selenium conjugates
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
AUPN214095A0 (en) * 1995-04-03 1995-04-27 Australian Water Technologies Pty Ltd Method for detecting microorganisms using flow cytometry
EP0880598A4 (de) 1996-01-23 2005-02-23 Affymetrix Inc Verfahren zur analyse von nukleinsäure
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5776711A (en) * 1996-11-12 1998-07-07 The Regents Of The University Of California Simultaneous human ABO and RH(D) blood typing or antibody screening by flow cytometry
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
CA2309528C (en) * 1999-06-08 2007-10-09 Ortho-Clinical Diagnostics, Inc. Simultaneous determination of forward and reverse abo blood group
GB2410793B (en) * 2004-02-05 2006-05-17 Elan Vital Fluid analyser systems
AU2007269609B2 (en) * 2006-07-06 2012-09-13 Board Of Regents Of The University Of Nebraska Polychromatic, diversely-sized particles for angiography
JP2018531328A (ja) 2015-08-14 2018-10-25 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 紙および板紙用の水性表面処理組成物

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US4108972A (en) * 1974-03-15 1978-08-22 Dreyer William J Immunological reagent employing radioactive and other tracers
US4199559A (en) * 1974-08-12 1980-04-22 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4100416A (en) * 1977-03-02 1978-07-11 Block Engineering, Inc. Serum fluorescence suppression
US4374925A (en) * 1978-11-24 1983-02-22 Syva Company Macromolecular environment control in specific receptor assays
US4274832A (en) * 1979-02-12 1981-06-23 Eastman Kodak Company Analytical element and method for analysis of multiple analytes
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4564598A (en) * 1982-07-12 1986-01-14 Syntex (U.S.A.) Inc. Limited volume method for particle counting
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4550017A (en) * 1982-10-15 1985-10-29 Syntex (U.S.A.) Inc. Fluorescence screening for blood typing

Also Published As

Publication number Publication date
US4584277A (en) 1986-04-22
EP0121442A2 (de) 1984-10-10
CA1225589A (en) 1987-08-18
DE3479057D1 (en) 1989-08-24
EP0121442B1 (de) 1989-07-19
JPS59195160A (ja) 1984-11-06
EP0121442A3 (en) 1985-08-07
JPH0565822B2 (de) 1993-09-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee