ATE432701T1 - Indol-6-sulfonamid-derivate, ihre herstellung und ihre verwendung als 5-ht-6 modulatoren - Google Patents
Indol-6-sulfonamid-derivate, ihre herstellung und ihre verwendung als 5-ht-6 modulatorenInfo
- Publication number
- ATE432701T1 ATE432701T1 AT04741319T AT04741319T ATE432701T1 AT E432701 T1 ATE432701 T1 AT E432701T1 AT 04741319 T AT04741319 T AT 04741319T AT 04741319 T AT04741319 T AT 04741319T AT E432701 T1 ATE432701 T1 AT E432701T1
- Authority
- AT
- Austria
- Prior art keywords
- indole
- modulators
- preparation
- sulfonamide derivatives
- sulfonamide
- Prior art date
Links
- AFJYOUBTIAOUQI-UHFFFAOYSA-N 1h-indole-6-sulfonamide Chemical class NS(=O)(=O)C1=CC=C2C=CNC2=C1 AFJYOUBTIAOUQI-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200301810A ES2222832B1 (es) | 2003-07-30 | 2003-07-30 | Derivados de 6-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos. |
PCT/EP2004/008510 WO2005013976A1 (en) | 2003-07-30 | 2004-07-29 | Indol-6 sulfonamide derivatives, their preparation and their use 5-ht-6 as modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE432701T1 true ATE432701T1 (de) | 2009-06-15 |
Family
ID=34130544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04741319T ATE432701T1 (de) | 2003-07-30 | 2004-07-29 | Indol-6-sulfonamid-derivate, ihre herstellung und ihre verwendung als 5-ht-6 modulatoren |
Country Status (22)
Country | Link |
---|---|
US (1) | US7462640B2 (de) |
EP (1) | EP1660077B1 (de) |
JP (1) | JP2007500164A (de) |
KR (1) | KR20060123699A (de) |
CN (1) | CN100563650C (de) |
AR (1) | AR045155A1 (de) |
AT (1) | ATE432701T1 (de) |
AU (1) | AU2004262484A1 (de) |
BR (1) | BRPI0413112A (de) |
CA (1) | CA2533970A1 (de) |
DE (1) | DE602004021394D1 (de) |
ES (2) | ES2222832B1 (de) |
IL (1) | IL172894A0 (de) |
MX (1) | MXPA06001141A (de) |
NO (1) | NO20060682L (de) |
NZ (1) | NZ545301A (de) |
PE (1) | PE20050280A1 (de) |
PT (1) | PT1660077E (de) |
RU (1) | RU2006105777A (de) |
TW (1) | TW200509907A (de) |
WO (1) | WO2005013976A1 (de) |
ZA (1) | ZA200600419B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2222832B1 (es) | 2003-07-30 | 2006-02-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de 6-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos. |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
KR20070083484A (ko) | 2004-07-14 | 2007-08-24 | 피티씨 테라퓨틱스, 인크. | C형 간염 치료 방법 |
ES2246721B1 (es) * | 2004-08-10 | 2007-03-16 | Laboratorios Del Dr. Esteve, S.A. | Compuestos indolicos sustituidos, su preparacion y su uso como medicamentos. |
EP1632491A1 (de) * | 2004-08-30 | 2006-03-08 | Laboratorios Del Dr. Esteve, S.A. | Substituierte indol-verbindungen und deren verwendung als modulatoren des 5-ht6 rezeptors |
ATE517883T1 (de) * | 2005-08-25 | 2011-08-15 | Schering Corp | Imidazolderivate als funktionelle selektive agonisten des alpha2c-adrenorezeptors |
PT1979314E (pt) * | 2006-01-24 | 2013-03-05 | Lilly Co Eli | Moduladores de indolesulfomamida de receptores de progesterona |
EP1953153A1 (de) * | 2007-01-31 | 2008-08-06 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituierte Sulfonamide für die Behandlung von Wahrnehmungsstörungen bzw. Ernährungserkrankungen |
DE102007007751A1 (de) * | 2007-02-16 | 2008-08-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
DE102007012284A1 (de) * | 2007-03-16 | 2008-09-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
EP2018861A1 (de) * | 2007-07-26 | 2009-01-28 | Laboratorios del Dr. Esteve S.A. | 5HT6-Liganden wie Sulfonamidederivaten bei wirkstoffinduzierter Gewichtszunahme |
DE102007035334A1 (de) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
DE102007035333A1 (de) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
DE602007012080D1 (de) | 2007-08-01 | 2011-03-03 | Esteve Labor Dr | Kombination von mindestens zwei 5-HT6-Liganden |
DE102007042154A1 (de) | 2007-09-05 | 2009-03-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel |
EP2053052A1 (de) | 2007-10-23 | 2009-04-29 | Laboratorios del Dr. Esteve S.A. | Verfahren zur Herstellung von 6-substituiertem Imidazo[2,1-b]thiazol-5-sulfonylhalogenid |
EP2116547A1 (de) * | 2008-05-09 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | Substituierte n-Imidazo[2,1-b]thiazol-5-sulfonamid-Derivative als 5-TH6-Liganden |
WO2009149392A1 (en) | 2008-06-06 | 2009-12-10 | Hollis-Eden Pharmaceuticals, Inc. | Methods for preparing 17-alkynyl-7-hydroxy steroids and related compounds |
ITMC20080120A1 (it) * | 2008-06-20 | 2009-12-21 | Nazario Luzi | Sistema di ripresa video in particolare per la pesca. |
EP2149573A1 (de) * | 2008-08-01 | 2010-02-03 | Laboratorios Del. Dr. Esteve, S.A. | Substituierte Indolsulfonamidverbindungen, ihre Herstellung und ihre Verwendung als Medikamente |
US20190336585A1 (en) * | 2018-05-03 | 2019-11-07 | John Lawrence Mee | Method for sustainable human cognitive enhancement |
US20190390193A1 (en) * | 2018-06-23 | 2019-12-26 | John Lawrence Mee | Reversible method for sustainable human cognitive enhancement |
MX2021003904A (es) | 2018-10-05 | 2021-10-26 | Annapurna Bio Inc | Compuestos y composiciones para el tratamiento de afecciones asociadas con la actividad del receptor apj. |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
AU2565595A (en) | 1994-05-28 | 1995-12-21 | Smithkline Beecham Plc | Amide derivatives having 5ht1d-antagonist activity |
WO1996029075A1 (en) | 1995-03-20 | 1996-09-26 | Eli Lilly And Company | 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists |
DE19625184B4 (de) | 1996-06-24 | 2005-06-30 | Wabag Wassertechnik Gmbh | Verfahren zur Aufbereitung von Prozeßwasser aus einer Flaschenreinigungsmaschine |
US5939451A (en) | 1996-06-28 | 1999-08-17 | Hoffmann-La Roche Inc. | Use of sulfonamides |
DE19753522A1 (de) * | 1997-12-03 | 1999-06-10 | Boehringer Ingelheim Pharma | Substituierte Indole, ihre Herstellung und ihre Verwendung als Arzneimittel |
GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
AU2002236730B2 (en) * | 2001-01-30 | 2006-06-15 | Eli Lilly And Company | Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-HT6 receptor |
ES2187300B1 (es) * | 2001-11-14 | 2004-06-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos. |
EP1626715B1 (de) * | 2003-05-09 | 2008-09-10 | Laboratorios Del Dr. Esteve, S.A. | Verwendung von sulfonamid-derivate zur herstellung eines medikaments für die vorbeugung oder behandlung von essstörungen |
CN1688497A (zh) * | 2003-06-02 | 2005-10-26 | 株式会社马里菲特 | 集装箱连结配件 |
ES2222832B1 (es) | 2003-07-30 | 2006-02-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de 6-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos. |
-
2003
- 2003-07-30 ES ES200301810A patent/ES2222832B1/es not_active Expired - Fee Related
-
2004
- 2004-07-29 NZ NZ545301A patent/NZ545301A/en unknown
- 2004-07-29 TW TW093122667A patent/TW200509907A/zh unknown
- 2004-07-29 EP EP04741319A patent/EP1660077B1/de not_active Expired - Lifetime
- 2004-07-29 KR KR1020067001738A patent/KR20060123699A/ko not_active Application Discontinuation
- 2004-07-29 MX MXPA06001141A patent/MXPA06001141A/es active IP Right Grant
- 2004-07-29 AR ARP040102697A patent/AR045155A1/es unknown
- 2004-07-29 JP JP2006521528A patent/JP2007500164A/ja active Pending
- 2004-07-29 AU AU2004262484A patent/AU2004262484A1/en not_active Abandoned
- 2004-07-29 ZA ZA200600419A patent/ZA200600419B/en unknown
- 2004-07-29 CN CNB2004800222711A patent/CN100563650C/zh not_active Expired - Fee Related
- 2004-07-29 WO PCT/EP2004/008510 patent/WO2005013976A1/en active Application Filing
- 2004-07-29 PT PT04741319T patent/PT1660077E/pt unknown
- 2004-07-29 CA CA002533970A patent/CA2533970A1/en not_active Abandoned
- 2004-07-29 US US10/566,101 patent/US7462640B2/en not_active Expired - Fee Related
- 2004-07-29 BR BRPI0413112-6A patent/BRPI0413112A/pt not_active IP Right Cessation
- 2004-07-29 RU RU2006105777/04A patent/RU2006105777A/ru unknown
- 2004-07-29 DE DE602004021394T patent/DE602004021394D1/de not_active Expired - Lifetime
- 2004-07-29 ES ES04741319T patent/ES2327845T3/es not_active Expired - Lifetime
- 2004-07-29 AT AT04741319T patent/ATE432701T1/de not_active IP Right Cessation
- 2004-08-02 PE PE2004000735A patent/PE20050280A1/es not_active Application Discontinuation
-
2005
- 2005-12-29 IL IL172894A patent/IL172894A0/en unknown
-
2006
- 2006-02-10 NO NO20060682A patent/NO20060682L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005013976A1 (en) | 2005-02-17 |
MXPA06001141A (es) | 2006-04-24 |
US20070043041A1 (en) | 2007-02-22 |
DE602004021394D1 (de) | 2009-07-16 |
AU2004262484A1 (en) | 2005-02-17 |
PT1660077E (pt) | 2009-09-03 |
CN1832738A (zh) | 2006-09-13 |
US7462640B2 (en) | 2008-12-09 |
RU2006105777A (ru) | 2007-09-20 |
EP1660077B1 (de) | 2009-06-03 |
NZ545301A (en) | 2008-05-30 |
CN100563650C (zh) | 2009-12-02 |
KR20060123699A (ko) | 2006-12-04 |
NO20060682L (no) | 2006-02-10 |
IL172894A0 (en) | 2006-06-11 |
PE20050280A1 (es) | 2005-06-12 |
EP1660077A1 (de) | 2006-05-31 |
ES2327845T3 (es) | 2009-11-04 |
CA2533970A1 (en) | 2005-02-17 |
BRPI0413112A (pt) | 2006-10-03 |
ES2222832A1 (es) | 2005-02-01 |
ZA200600419B (en) | 2007-03-28 |
AR045155A1 (es) | 2005-10-19 |
TW200509907A (en) | 2005-03-16 |
JP2007500164A (ja) | 2007-01-11 |
ES2222832B1 (es) | 2006-02-16 |
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