[go: up one dir, main page]

ATE42102T1 - Pyridylphenylpyridazinone, inotrope mittel. - Google Patents

Pyridylphenylpyridazinone, inotrope mittel.

Info

Publication number
ATE42102T1
ATE42102T1 AT85307339T AT85307339T ATE42102T1 AT E42102 T1 ATE42102 T1 AT E42102T1 AT 85307339 T AT85307339 T AT 85307339T AT 85307339 T AT85307339 T AT 85307339T AT E42102 T1 ATE42102 T1 AT E42102T1
Authority
AT
Austria
Prior art keywords
sub
pyridylphenylpyridazinone
inotropic agent
inotropic
agent
Prior art date
Application number
AT85307339T
Other languages
English (en)
Inventor
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE42102T1 publication Critical patent/ATE42102T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT85307339T 1984-10-15 1985-10-14 Pyridylphenylpyridazinone, inotrope mittel. ATE42102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/660,840 US4631279A (en) 1984-10-15 1984-10-15 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents
EP85307339A EP0178875B1 (de) 1984-10-15 1985-10-14 Pyridylphenylpyridazinone, inotrope Mittel

Publications (1)

Publication Number Publication Date
ATE42102T1 true ATE42102T1 (de) 1989-04-15

Family

ID=24651187

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85307339T ATE42102T1 (de) 1984-10-15 1985-10-14 Pyridylphenylpyridazinone, inotrope mittel.

Country Status (6)

Country Link
US (1) US4631279A (de)
EP (1) EP0178875B1 (de)
JP (1) JPS6197284A (de)
AT (1) ATE42102T1 (de)
CA (1) CA1251210A (de)
DE (1) DE3569380D1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6144873A (ja) * 1984-08-10 1986-03-04 Mitsubishi Chem Ind Ltd ピリダジノン誘導体またはその塩類
IL79280A (en) * 1985-07-05 1990-07-12 Smith Kline French Lab 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them
US4888169A (en) * 1986-10-14 1989-12-19 Norden Laboratories, Inc. Bordetella Bronchiseptica vaccine
DE3706427A1 (de) * 1987-02-27 1988-09-08 Boehringer Mannheim Gmbh Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
BE790106A (fr) * 1971-10-14 1973-04-13 Basf Ag Dihydropyridazones, leur preparation et leurs utilisations therapeutiques
US4177273A (en) * 1977-02-14 1979-12-04 Sandoz, Inc. 6-(Substituted phenyl)-4,5-dihydro-pyridazin-3(2H)-ones
DE2845456A1 (de) * 1978-10-19 1980-08-14 Merck Patent Gmbh 6-arylpyridazin-3-one und verfahren zu ihrer herstellung
US4298609A (en) * 1979-08-30 1981-11-03 Sterling Drug Inc. 4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents
US4304777A (en) * 1979-08-30 1981-12-08 Sterling Drug Inc. 6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
US4404203A (en) * 1981-05-14 1983-09-13 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4397854A (en) * 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4353905A (en) * 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
IE54598B1 (en) * 1981-11-12 1989-12-06 Ici Plc Pharmaceutically-active pyridylvinylpyridazinones
DE3212304A1 (de) * 1982-04-02 1983-10-06 Nattermann A & Cie Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4521416A (en) * 1983-03-22 1985-06-04 Warner-Lambert Company 4,5-Dihydro-6-[(substituted)-1H-imidazol-4-yl or 5-yl]-3(2H)-pyridazinones and 6-[(substituted)-1H-imidazol-4-yl or 5-yl]-3(2H)-pyridazinones

Also Published As

Publication number Publication date
EP0178875A1 (de) 1986-04-23
US4631279A (en) 1986-12-23
JPS6197284A (ja) 1986-05-15
EP0178875B1 (de) 1989-04-12
DE3569380D1 (en) 1989-05-18
CA1251210A (en) 1989-03-14

Similar Documents

Publication Publication Date Title
EP0097534A3 (en) Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
IL148516A (en) Retroviral protease inhibiting compound
FI882390A (fi) Tetratsolit, jotka ovat verenpainetta alentavien yhdisteiden välituotteita
IT1283588B1 (it) Miscela sinergica di agenti stabilizzanti
JPS57114555A (en) 3-aryloxy-3-phenylpropylamine and manufacture
BG103485A (en) Ketobanzamides as calpain inhibitors
DE3572816D1 (de) Pyridazinone inotropic agents
ATE42102T1 (de) Pyridylphenylpyridazinone, inotrope mittel.
ES8701159A1 (es) Procedimiento para la obtencion de derivados de piperidina con actividad cardiovascular.
IL66943A (en) Compositions containing substituted hydroxy-malonic acid diamides and their use for combating insects and acarids
ES2062389T3 (es) Acidos glutaramicos sustituidos y sus derivados.
ES8701737A1 (es) Un procedimiento para la preparacion de nuevas quinazolindionas.
ATE75933T1 (de) Zahnaerztliche haftmittelzusammensetzung.
DK259589D0 (da) Joderede, ikke-ioniske trijodbenzenforbindelser og kontrastmiddel indeholdende dem
DK365284D0 (da) 5-substituerede (1,2,4)triazolo(1,5-c)pyrimidin-2-aminer
ATE171622T1 (de) Antiallergische zusammensetzung enthaltend eine phosphorsäurediester-verbindung
AU590793B2 (en) Phenoxy pthalide derivatives
RO91594A (ro) Compozitie erbicida solida
WO1986007357A2 (en) Cyclopentapyrazole and tetrahydroindazole compounds
ES8801647A1 (es) Un procedimiento para la preparacion de piridazinilimidazolidinonas
AU566243B2 (en) Optically active imidazolylpropanols
ES2053808T3 (es) Nuevos compuestos azolicos.
ES8708132A1 (es) Procedimiento para preparar n-fenil-4-fenil-1-piperazincarboxamidinas y compuestos afines como agentes anti-arritmicos
DE69615814D1 (de) Uch-15-verbindungen
EP0120304A3 (de) Substituierte 4,10-Dihydro-10-oxothienobenzoxepine und Zwischenprodukte, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee