[go: up one dir, main page]

ATE420067T1 - Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung - Google Patents

Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung

Info

Publication number
ATE420067T1
ATE420067T1 AT01980959T AT01980959T ATE420067T1 AT E420067 T1 ATE420067 T1 AT E420067T1 AT 01980959 T AT01980959 T AT 01980959T AT 01980959 T AT01980959 T AT 01980959T AT E420067 T1 ATE420067 T1 AT E420067T1
Authority
AT
Austria
Prior art keywords
sup
pharmaceutically acceptable
production
acceptable salts
peptide derivatives
Prior art date
Application number
AT01980959T
Other languages
English (en)
Inventor
Kenji Yamamoto
Yoshimitsu Suda
Tetsuji Asao
Original Assignee
Univ Kyushu Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyushu Nat Univ Corp filed Critical Univ Kyushu Nat Univ Corp
Application granted granted Critical
Publication of ATE420067T1 publication Critical patent/ATE420067T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01980959T 2000-11-06 2001-11-02 Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung ATE420067T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000338192 2000-11-06

Publications (1)

Publication Number Publication Date
ATE420067T1 true ATE420067T1 (de) 2009-01-15

Family

ID=18813440

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01980959T ATE420067T1 (de) 2000-11-06 2001-11-02 Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung

Country Status (10)

Country Link
US (1) US6951843B2 (de)
EP (1) EP1333024B1 (de)
JP (1) JP4601249B2 (de)
KR (1) KR100559306B1 (de)
CN (1) CN1194006C (de)
AT (1) ATE420067T1 (de)
AU (1) AU782470B2 (de)
CA (1) CA2396678C (de)
DE (1) DE60137352D1 (de)
WO (1) WO2002036551A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE338057T1 (de) 2001-11-16 2006-09-15 Taiho Pharmaceutical Co Ltd Peptidderivat, pharmazeutisch unbedenkliches salz davon, verfahren zu dessen herstellung und dessen verwendung
CN100446522C (zh) * 2005-10-28 2008-12-24 环达电脑(上海)有限公司 Pda设备上基于蓝牙技术实现手机免提通话的方法
JP5397851B2 (ja) * 2009-05-21 2014-01-22 Nsマテリアルズ株式会社 ペプチド誘導体又はその塩の製造方法
WO2017201322A1 (en) * 2016-05-19 2017-11-23 Cortexyme, Inc. Treatment of osteoarthritis with gingipain blocking agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341029C (en) 1985-02-04 2000-06-20 Michael Kolb Peptidase inhibitors
US5496927A (en) * 1985-02-04 1996-03-05 Merrell Pharmaceuticals Inc. Peptidase inhibitors
JPH0597708A (ja) 1991-10-02 1993-04-20 Lion Corp 歯周病治療剤
US6066622A (en) * 1991-10-28 2000-05-23 Cytran, Inc. Immunomodulating peptides and methods of use
US6100380A (en) * 1991-10-28 2000-08-08 Cytran, Inc. Immunomodulating peptides and methods of use
JP3873429B2 (ja) 1998-02-20 2007-01-24 大鵬薬品工業株式会社 ペプチド誘導体及びその薬学的に許容される塩、その製造方法及びその用途
WO2002030473A1 (en) * 2000-10-11 2002-04-18 Targesome, Inc. Targeted therapeutic agents

Also Published As

Publication number Publication date
CN1394199A (zh) 2003-01-29
US6951843B2 (en) 2005-10-04
EP1333024A4 (de) 2005-11-16
EP1333024A1 (de) 2003-08-06
WO2002036551A1 (fr) 2002-05-10
CA2396678A1 (en) 2002-05-10
JP4601249B2 (ja) 2010-12-22
US20030087828A1 (en) 2003-05-08
JPWO2002036551A1 (ja) 2004-03-11
CN1194006C (zh) 2005-03-23
CA2396678C (en) 2009-01-20
AU782470B2 (en) 2005-08-04
KR20020067597A (ko) 2002-08-22
AU1270402A (en) 2002-05-15
EP1333024B1 (de) 2009-01-07
KR100559306B1 (ko) 2006-03-15
DE60137352D1 (de) 2009-02-26

Similar Documents

Publication Publication Date Title
ATE253545T1 (de) Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren
NO953305D0 (no) Antranilsyrederivat
EP1462447A3 (de) Verfahren zur Herstellung von reinem Citalopram
DK0891325T3 (da) Para-substituerede phenylpropansyrederivater som integrinantagonister
EA200300674A1 (ru) Получение гетероциклических сульфонамидных ингибиторов бета-амилоида
ATE203515T1 (de) Meta-substituierte phenylsulphonamidderivate
DK0894084T3 (da) Kanelsyrederivater og deres anvendelse som integrinantagonister
CA2446944A1 (en) Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use
DE69923300D1 (de) Cycloalken-derivate, verfahren zu ihrer herstellung und ihre verwendung
DE50011034D1 (de) N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE332304T1 (de) Cefdinir salze als zwischenprodukte
ATE429429T1 (de) Pharmazeutisches verfahren und damit hergestellte verbindungen
AT379800B (de) Verfahren zur herstellung von neuen 2-oxazetidin-derivaten
DE59408399D1 (de) Arylessigsäurederivate und ihre verwendung als fungizide
ATE475421T1 (de) Pyrazoloä4,3-düpyrimidines, verfahren zur ihre herstellung und deren verwendung
ATE239741T1 (de) Derivate der phosphonsäure zur inhibierung von carboxypeptidase b
ES2160158T3 (es) Derivados de 4-indol-1-il acido butirico, su preparacion y su utilizacion como inhibidores de receptores alfa1-adrenergicos y testosterona 5alfa-reductasas.
ATE420067T1 (de) Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung
AR019197A1 (es) COMPUESTOS DERIVADOS DE PIPERIDINA ANTIHISTAMINICOS, COMPUESTOS INTERMEDIOS, PROCEDIMIENTO DE PREPARACIoN DE DERIVADOS DE PIPERIDINA Y PROCEDIMIENTOS DE PREPARACIoN DE INTERMEDIARIOS.
AU655869B2 (en) An amphoteric tricyclic compound
DE60228070D1 (de) Insektizid sowie verfahren zur bekämpfung von insekten
DE60214414D1 (de) Peptidderivat, pharmazeutisch unbedenkliches salz davon, verfahren zu dessen herstellung und dessen verwendung
ATE265453T1 (de) Diketopiperazinderivate als thrombininhibitoren
MX9604347A (es) Derivados del acido 2-(4-pirazoliloxi-pirimidin-5-il) acetico.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties