ATE420067T1 - Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung - Google Patents
Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendungInfo
- Publication number
- ATE420067T1 ATE420067T1 AT01980959T AT01980959T ATE420067T1 AT E420067 T1 ATE420067 T1 AT E420067T1 AT 01980959 T AT01980959 T AT 01980959T AT 01980959 T AT01980959 T AT 01980959T AT E420067 T1 ATE420067 T1 AT E420067T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- pharmaceutically acceptable
- production
- acceptable salts
- peptide derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000338192 | 2000-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE420067T1 true ATE420067T1 (de) | 2009-01-15 |
Family
ID=18813440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01980959T ATE420067T1 (de) | 2000-11-06 | 2001-11-02 | Peptid-derivate und ihre pharmazeutisch akzeptablensalze, verfahren zur herstellung von beiden und ihre verwendung |
Country Status (10)
Country | Link |
---|---|
US (1) | US6951843B2 (de) |
EP (1) | EP1333024B1 (de) |
JP (1) | JP4601249B2 (de) |
KR (1) | KR100559306B1 (de) |
CN (1) | CN1194006C (de) |
AT (1) | ATE420067T1 (de) |
AU (1) | AU782470B2 (de) |
CA (1) | CA2396678C (de) |
DE (1) | DE60137352D1 (de) |
WO (1) | WO2002036551A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE338057T1 (de) | 2001-11-16 | 2006-09-15 | Taiho Pharmaceutical Co Ltd | Peptidderivat, pharmazeutisch unbedenkliches salz davon, verfahren zu dessen herstellung und dessen verwendung |
CN100446522C (zh) * | 2005-10-28 | 2008-12-24 | 环达电脑(上海)有限公司 | Pda设备上基于蓝牙技术实现手机免提通话的方法 |
JP5397851B2 (ja) * | 2009-05-21 | 2014-01-22 | Nsマテリアルズ株式会社 | ペプチド誘導体又はその塩の製造方法 |
WO2017201322A1 (en) * | 2016-05-19 | 2017-11-23 | Cortexyme, Inc. | Treatment of osteoarthritis with gingipain blocking agents |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341029C (en) | 1985-02-04 | 2000-06-20 | Michael Kolb | Peptidase inhibitors |
US5496927A (en) * | 1985-02-04 | 1996-03-05 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
JPH0597708A (ja) | 1991-10-02 | 1993-04-20 | Lion Corp | 歯周病治療剤 |
US6066622A (en) * | 1991-10-28 | 2000-05-23 | Cytran, Inc. | Immunomodulating peptides and methods of use |
US6100380A (en) * | 1991-10-28 | 2000-08-08 | Cytran, Inc. | Immunomodulating peptides and methods of use |
JP3873429B2 (ja) | 1998-02-20 | 2007-01-24 | 大鵬薬品工業株式会社 | ペプチド誘導体及びその薬学的に許容される塩、その製造方法及びその用途 |
WO2002030473A1 (en) * | 2000-10-11 | 2002-04-18 | Targesome, Inc. | Targeted therapeutic agents |
-
2001
- 2001-11-02 CN CNB018034748A patent/CN1194006C/zh not_active Expired - Fee Related
- 2001-11-02 US US10/168,540 patent/US6951843B2/en not_active Expired - Fee Related
- 2001-11-02 EP EP01980959A patent/EP1333024B1/de not_active Expired - Lifetime
- 2001-11-02 KR KR1020027008680A patent/KR100559306B1/ko not_active Expired - Fee Related
- 2001-11-02 AU AU12704/02A patent/AU782470B2/en not_active Ceased
- 2001-11-02 DE DE60137352T patent/DE60137352D1/de not_active Expired - Lifetime
- 2001-11-02 CA CA002396678A patent/CA2396678C/en not_active Expired - Fee Related
- 2001-11-02 WO PCT/JP2001/009621 patent/WO2002036551A1/ja active IP Right Grant
- 2001-11-02 AT AT01980959T patent/ATE420067T1/de not_active IP Right Cessation
- 2001-11-02 JP JP2002539311A patent/JP4601249B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1394199A (zh) | 2003-01-29 |
US6951843B2 (en) | 2005-10-04 |
EP1333024A4 (de) | 2005-11-16 |
EP1333024A1 (de) | 2003-08-06 |
WO2002036551A1 (fr) | 2002-05-10 |
CA2396678A1 (en) | 2002-05-10 |
JP4601249B2 (ja) | 2010-12-22 |
US20030087828A1 (en) | 2003-05-08 |
JPWO2002036551A1 (ja) | 2004-03-11 |
CN1194006C (zh) | 2005-03-23 |
CA2396678C (en) | 2009-01-20 |
AU782470B2 (en) | 2005-08-04 |
KR20020067597A (ko) | 2002-08-22 |
AU1270402A (en) | 2002-05-15 |
EP1333024B1 (de) | 2009-01-07 |
KR100559306B1 (ko) | 2006-03-15 |
DE60137352D1 (de) | 2009-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |