[go: up one dir, main page]

ATE414795T1 - Antikörperbibliotheken - Google Patents

Antikörperbibliotheken

Info

Publication number
ATE414795T1
ATE414795T1 AT03745659T AT03745659T ATE414795T1 AT E414795 T1 ATE414795 T1 AT E414795T1 AT 03745659 T AT03745659 T AT 03745659T AT 03745659 T AT03745659 T AT 03745659T AT E414795 T1 ATE414795 T1 AT E414795T1
Authority
AT
Austria
Prior art keywords
present
libraries
relates
antibodies
antibody
Prior art date
Application number
AT03745659T
Other languages
English (en)
Inventor
Robert Bremel
Kurt Eakle
Michael Imboden
Original Assignee
Gala Design Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gala Design Inc filed Critical Gala Design Inc
Application granted granted Critical
Publication of ATE414795T1 publication Critical patent/ATE414795T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03745659T 2002-03-28 2003-03-28 Antikörperbibliotheken ATE414795T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36880802P 2002-03-28 2002-03-28
US37129902P 2002-04-10 2002-04-10

Publications (1)

Publication Number Publication Date
ATE414795T1 true ATE414795T1 (de) 2008-12-15

Family

ID=28678256

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03745659T ATE414795T1 (de) 2002-03-28 2003-03-28 Antikörperbibliotheken

Country Status (6)

Country Link
US (2) US20040038304A1 (de)
EP (1) EP1495146B1 (de)
AT (1) ATE414795T1 (de)
AU (1) AU2003226127A1 (de)
DE (1) DE60324779D1 (de)
WO (1) WO2003083077A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7384738B2 (en) 2002-03-28 2008-06-10 Bremel Robert D Retrovirus-based genomic screening
DK1572994T3 (da) 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer
US7696322B2 (en) * 2003-07-28 2010-04-13 Catalent Pharma Solutions, Inc. Fusion antibodies
AU2004276522B2 (en) * 2003-09-26 2010-12-02 Merck Serono Sa Leader sequences for use in production of proteins
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
AU2005300503B2 (en) * 2004-11-08 2010-12-16 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
ES2384391T3 (es) 2004-11-08 2012-07-04 Chromagenics B.V. Selección de células hospedantes que expresan proteína a altos niveles
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
US10278711B2 (en) * 2006-02-27 2019-05-07 Biomet Manufacturing, Llc Patient-specific femoral guide
US7846434B2 (en) 2006-10-24 2010-12-07 Trubion Pharmaceuticals, Inc. Materials and methods for improved immunoglycoproteins
JP2010507394A (ja) * 2006-10-24 2010-03-11 トルービオン ファーマスーティカルズ インコーポレイテッド 改良免疫糖タンパク質のための物質および方法
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
EP2098536A1 (de) 2008-03-05 2009-09-09 4-Antibody AG Isolation und Identifikation antigen- oder ligandenspezifischer Bindungsproteine
MX2011012299A (es) 2009-05-20 2012-03-29 Novimmune Sa Librerias de polipeptidos sinteticos y metodos para generar variantes de polipeptido naturalmente diversificadas.
RS60122B1 (sr) 2012-10-30 2020-05-29 Mei Pharma Inc Kombinovane terapije za lečenje hemorezistentnih kancera
CA3180705A1 (en) * 2020-06-02 2021-12-09 Catalent Pharma Solutions, Llc Cell lines with multiple docks for gene insertion

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560655A (en) * 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) * 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
CA1220733A (en) * 1982-12-27 1987-04-21 Shigeru Takahashi Method for promoting fusion of plant protoplast
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4767704A (en) * 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
US5149645A (en) * 1984-06-04 1992-09-22 Rijksuniversiteit Leiden Process for introducing foreign DNA into the genome of plants
US4743548A (en) 1984-09-25 1988-05-10 Calgene, Inc. Plant cell microinjection technique
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5139941A (en) * 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5583024A (en) * 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase
US4927762A (en) * 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ATE87032T1 (de) * 1986-12-05 1993-04-15 Ciba Geigy Ag Verbessertes verfahren zur transformation von pflanzlichen protoplasten.
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
DE3856108T2 (de) * 1987-07-15 1998-07-09 The United States Of America, Represented By The Secretary, U.S. Department Of Commerce, Springfield, Va. Monoklonale antikörper der zweiten generation mit bindungsspezifität für tag-72 und menschliche karzinome sowie methoden zu ihrer anwendung
US4937190A (en) * 1987-10-15 1990-06-26 Wisconsin Alumni Research Foundation Translation enhancer
US5591624A (en) * 1988-03-21 1997-01-07 Chiron Viagene, Inc. Retroviral packaging cell lines
EP0435911B1 (de) 1988-09-23 1996-03-13 Cetus Oncology Corporation Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
US5993813A (en) * 1988-10-19 1999-11-30 The Dow Chemical Company Family of high affinity, modified antibodies for cancer treatment
US5215904A (en) * 1989-01-27 1993-06-01 Wisconsin Alumni Research Foundation Method for producing a recombinant mammal in vivo
US5225347A (en) * 1989-09-25 1993-07-06 Innovir Laboratories, Inc. Therapeutic ribozyme compositions and expression vectors
WO1991006677A1 (en) * 1989-10-25 1991-05-16 The Salk Institute For Biological Studies Receptor infection assay
US5780225A (en) * 1990-01-12 1998-07-14 Stratagene Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
US5364783A (en) * 1990-05-14 1994-11-15 Massachusetts Institute Of Technology Retrovirus promoter-trap vectors
AU8200191A (en) 1990-07-09 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The High efficiency packaging of mutant adeno-associated virus using amber suppressions
US5817491A (en) * 1990-09-21 1998-10-06 The Regents Of The University Of California VSV G pseusdotyped retroviral vectors
US5122469A (en) * 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
US6027722A (en) * 1990-10-25 2000-02-22 Nature Technology Corporation Vectors for gene transfer
US5173414A (en) * 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5512421A (en) * 1991-02-19 1996-04-30 The Regents Of The University Of California Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors
JP3955316B2 (ja) * 1991-06-21 2007-08-08 ザ・ワルター・アンド・エリザ・ホール・インスティテュート・オヴ・メディカル・リサーチ 新規レセプター型チロシンキナーゼ及びその用途
JP3048640B2 (ja) 1991-07-25 2000-06-05 アイデック・ファーマシュウティカルズ・コーポレーション ヒトの治療のための組換え抗体
DK0598029T3 (da) 1991-08-07 2002-05-27 W French Anderson Retrovirale vektorer indeholdende interne ribosome indgangssteder
US6368862B1 (en) * 1991-08-12 2002-04-09 Fred Hutchinson Cancer Research Center Polymerase I promoter plasmid and vector constructs
US6319707B1 (en) * 1991-08-12 2001-11-20 Fred Hutchinson Cancer Research Center Board Regents Of The University Of Washington Cap-independent multicistronic retroviral vectors
AU663101B2 (en) * 1991-08-13 1995-09-28 Wisconsin Milk Marketing Board DNA sequence encoding bovine alpha-lactalbumin and methods of use
ATE237694T1 (de) 1991-08-20 2003-05-15 Us Gov Health & Human Serv Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
US5994074A (en) * 1991-11-18 1999-11-30 Cold Spring Harbor Laboratories Human cdc25 genes, encoded products and uses thereof
US5670113A (en) * 1991-12-20 1997-09-23 Sibia Neurosciences, Inc. Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
MX9304769A (es) * 1992-08-05 1994-05-31 Max Planck Gesellschaft Subfamilia ptp-d de fosfatasas de la proteina tirosina.
DE4228457A1 (de) 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
ATE245703T1 (de) * 1992-09-22 2003-08-15 Biofocus Discovery Ltd Rekombinante viren, die an ihrer äusseren oberfläche ein nichtvirales polypeptid präsentieren
US5589375A (en) * 1992-10-06 1996-12-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. PTP 1D: a novel protein tyrosine phosphatase
EP0706319A4 (de) 1993-01-20 1998-04-22 Biotransplant Inc Retrovirale vektoren mit der fähigkeit zur expression multimerer proteine von mehreren translationsinitiations-orten
AT401526B (de) * 1993-02-10 1996-09-25 Scheirer Winfried Reagenzlösung zur stabilisierung der lumineszenz bei der luciferasemessung
US5459036A (en) * 1993-03-19 1995-10-17 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Extracellular signal-regulated kinase, sequences, and methods of production and use
US5585233A (en) * 1993-03-23 1996-12-17 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. PTP-S31: A novel protein tyrosine phosphatase
US6001581A (en) * 1993-06-04 1999-12-14 Sibia Neurosciences, Inc. Cation-based bioassay using human metabotropic glutamate receptors
US6051427A (en) * 1993-06-11 2000-04-18 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
US5834256A (en) * 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
AU7321294A (en) * 1993-06-30 1995-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Transformed eukaryotic cells, and transposon-based transformation vectors
US5534423A (en) * 1993-10-08 1996-07-09 Regents Of The University Of Michigan Methods of increasing rates of infection by directing motion of vectors
FR2716459B1 (fr) * 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
US5677170A (en) * 1994-03-02 1997-10-14 The Johns Hopkins University In vitro transposition of artificial transposons
US6013517A (en) * 1994-05-09 2000-01-11 Chiron Corporation Crossless retroviral vectors
JP3053873B2 (ja) * 1994-08-12 2000-06-19 イムノメディクス，インコーポレイテッド Ｂ細胞リンパ腫細胞および白血病細胞に特異的な免疫結合体およびヒト化抗体
US5874540A (en) * 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
DE4439662C2 (de) * 1994-11-07 1997-10-02 Max Planck Gesellschaft Verfahren zur Aktivitätsbestimmung von Phosphotyrosinphosphatasen und zur Identifizierung von Effektoren davon
US5843742A (en) * 1994-12-16 1998-12-01 Avigen Incorporated Adeno-associated derived vector systems for gene delivery and integration into target cells
US5518911A (en) * 1995-01-06 1996-05-21 Onyx Pharmaceuticals, Inc. Human PAK65
US5922601A (en) * 1995-01-19 1999-07-13 Biotransplant, Inc. High efficiency gene trap selection of regulated genetic loci
US5686120A (en) * 1995-05-22 1997-11-11 Wisconsin Alumni Research Foundation Pre-mRNA processing enhancer and method for intron-independent gene expression
US5721121A (en) * 1995-06-06 1998-02-24 Genentech, Inc. Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein
PT937098E (pt) * 1995-06-07 2002-12-31 Invitrogen Corp Clonagem recombinatoria in vitro utilizando locais de recombinacao modificados
US6013516A (en) * 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
DK0776895T3 (da) * 1995-11-20 1999-06-23 Lilly Co Eli Proteinkinase C inhibitor
US5976853A (en) * 1996-03-21 1999-11-02 New York University Medical Center Growth factor inducible serine/threonine phosphatase FIN13
US5814507A (en) * 1996-05-24 1998-09-29 Genentech, Inc. κ/μ-like protein tyrosine phosphatase, PTP λ
US5965443A (en) * 1996-09-09 1999-10-12 Wisconsin Alumni Research Foundation System for in vitro transposition
US6255071B1 (en) * 1996-09-20 2001-07-03 Cold Spring Harbor Laboratory Mammalian viral vectors and their uses
US6025192A (en) * 1996-09-20 2000-02-15 Cold Spring Harbor Laboratory Modified retroviral vectors
US5976796A (en) * 1996-10-04 1999-11-02 Loma Linda University Construction and expression of renilla luciferase and green fluorescent protein fusion genes
US6004791A (en) * 1996-11-13 1999-12-21 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Protein tyrosine phosphatase PTP20 and related products and methods
US6743620B1 (en) * 1996-12-16 2004-06-01 Eisai Co., Ltd. Method for preparing retrovirus vector for gene therapy
US5968800A (en) * 1997-02-07 1999-10-19 Merck & Co., Inc. Cyclin-dependent protein kinase
US6080912A (en) * 1997-03-20 2000-06-27 Wisconsin Alumni Research Foundation Methods for creating transgenic animals
US5876946A (en) * 1997-06-03 1999-03-02 Pharmacopeia, Inc. High-throughput assay
US6074859A (en) * 1997-07-08 2000-06-13 Kikkoman Corporation Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
US5958775A (en) * 1997-07-25 1999-09-28 Thomas Jefferson University Composition and method for targeted integration into cells
KR100228493B1 (ko) * 1997-08-30 1999-11-01 윤종용 비대칭 디지털 가입자 라인 시스템에서 송출 전력제어방법
US6136597A (en) 1997-09-18 2000-10-24 The Salk Institute For Biological Studies RNA export element
US5994136A (en) * 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
US6034228A (en) * 1998-12-15 2000-03-07 Zeneca Limited Human signal transduction serine/threonine kinase
AU753907B2 (en) 1998-02-24 2002-10-31 Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Trans-somatics with gene transfer into mammary epithelial cells
US6248825B1 (en) 1998-05-06 2001-06-19 Bridgestone Corporation Gels derived from extending grafted centipede polymers and polypropylene
JP2002519069A (ja) * 1998-07-01 2002-07-02 オーストリアン・ノルディック・バイオセラピューティクス・アーゲー レトロウイルスベクターを用いた染色体へのターゲッティングされた組込み
US6013455A (en) * 1998-10-15 2000-01-11 Incyte Pharmaceuticals, Inc. Protein kinase homologs
GB9825524D0 (en) * 1998-11-20 1999-01-13 Oxford Biomedica Ltd Vector
EP1157114A4 (de) * 1999-02-02 2002-05-02 Univ Jefferson Gentechnisch veränderte retrovirale vektorpartikel für die infektion von sich nicht teilenden zellen
WO2000055343A2 (en) * 1999-03-15 2000-09-21 Chiron Corporation Retrovirus producting cells utilizing a high multiplicity of transduction
US7033781B1 (en) * 1999-09-29 2006-04-25 Diversa Corporation Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating
DK1250453T3 (da) * 1999-12-10 2008-08-11 Invitrogen Corp Anvendelse af multiple rekombinations-sites med unik specificitet i rekombinationskloning
EP1297168A2 (de) * 2000-07-03 2003-04-02 Gala Design, Inc. Expressionsvektoren
AU7161401A (en) * 2000-07-03 2002-01-14 Gala Design Inc Host cells containing multiple integrating vectors
US6852510B2 (en) * 2000-07-03 2005-02-08 Gala Design Inc Host cells containing multiple integrating vectors

Also Published As

Publication number Publication date
WO2003083077A2 (en) 2003-10-09
US20100009869A1 (en) 2010-01-14
US20040038304A1 (en) 2004-02-26
AU2003226127A8 (en) 2003-10-13
DE60324779D1 (de) 2009-01-02
US8222188B2 (en) 2012-07-17
WO2003083077A3 (en) 2003-12-11
EP1495146B1 (de) 2008-11-19
EP1495146A4 (de) 2006-06-07
EP1495146A2 (de) 2005-01-12
AU2003226127A1 (en) 2003-10-13

Similar Documents

Publication Publication Date Title
DE60324779D1 (de) Antikörperbibliotheken
IL199259A0 (en) Artificial receptors, building blocks, and methods
ATE514717T1 (de) Rekombinante produktion von antikörpermischungen
ATE393169T1 (de) Il-7-fusionsproteine mit antikörperportionen, deren herstellung und deren verwendung
CY1116913T1 (el) Τροποποιημενα κλασματα fab αντισωματων
DZ3147A1 (fr) Méthode de surveillance sismique d'une zone souterraine par utilisation simultanée de plusieurs sources vibrosismiques.
CY1112101T1 (el) Νευροτροφικοι παραγοντες
CY1107669T1 (el) Απλης αλυσου vhh αντισωματα καμηλοειδους και μεθοδος για την παρασκευη αυτου σε ενα θηλαστικο
DE60228995D1 (de) Arrayplatten und verfahren zur herstellung von arrayplatten
CY1115730T1 (el) Θεραπευτικοι επιτοποι και χρησεις αυτων
EP1605058A4 (de) Verfahren zum screening der leichten kette eines antikörpers
CY1108471T1 (el) Μεθοδος για την παραγωγη εστερων σκοπινης
EA200300464A1 (ru) ГУМАНИЗИРОВАННОЕ АНТИТЕЛО ПРОТИВ РЕЦЕПТОРА ЛИМФОТОКСИНА-β (ВАРИАНТЫ), КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ИЛИ СНИЖЕНИЯ РИСКА РАЗВИТИЯ, ТЯЖЕСТИ ИЛИ ПОСЛЕДСТВИЙ НЕОПЛАЗИИ У ЧЕЛОВЕКА, ВЫДЕЛЕННАЯ НУКЛЕИНОВАЯ КИСЛОТА (ВАРИАНТЫ), КЛЕТКА КЛЕТОЧНОЙ ЛИНИИ
EA200300362A1 (ru) Способ генерирования молекулярно-функциональной сети
EA200500064A1 (ru) Многофункциональные маркеры продуктов и способы их получения и применения
EA200401621A1 (ru) Модуляторы сск-1 рецепторов
DK1485411T3 (da) Arrays af cytosoliske accessoriske proteiner immobiliseret på en overflade og relevante fremgangsmåder
ATE371749T1 (de) Matrix-screening-verfahren
HK1072078A (en) Antibody libraries
EA200500878A1 (ru) Кальцилитические соединения
ATE331038T1 (de) Verbessertes verfahren für reverses n-hybrid- screening
DE602006010187D1 (de) Einzelsequenzhybridisierungssonden
CY1109904T1 (el) Προαγωγεας της il-18bp, η παρασκευη και χρηση του
CY1109583T1 (el) Κυτοκινες θηλαστικων, αντιστοιχα αντιδραστηρια
CY1106200T1 (el) Αντισωματα εναντια σε κασπαση-8, παρασκευη και χρηση τους

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties