ATE406452T1 - Retrovirale vektoren - Google Patents
Retrovirale vektorenInfo
- Publication number
- ATE406452T1 ATE406452T1 AT97909438T AT97909438T ATE406452T1 AT E406452 T1 ATE406452 T1 AT E406452T1 AT 97909438 T AT97909438 T AT 97909438T AT 97909438 T AT97909438 T AT 97909438T AT E406452 T1 ATE406452 T1 AT E406452T1
- Authority
- AT
- Austria
- Prior art keywords
- dependent
- hiv
- rev
- transcription unit
- provirus
- Prior art date
Links
- 230000001177 retroviral effect Effects 0.000 title abstract 2
- 239000013598 vector Substances 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000035897 transcription Effects 0.000 abstract 2
- 238000013518 transcription Methods 0.000 abstract 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 1
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108091027981 Response element Proteins 0.000 abstract 1
- 210000000805 cytoplasm Anatomy 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9621679.1A GB9621679D0 (en) | 1996-10-17 | 1996-10-17 | Improved retroviral vectors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE406452T1 true ATE406452T1 (de) | 2008-09-15 |
Family
ID=10801597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97909438T ATE406452T1 (de) | 1996-10-17 | 1997-10-17 | Retrovirale vektoren |
Country Status (8)
Country | Link |
---|---|
US (2) | US20020141978A1 (de) |
EP (1) | EP0931157B1 (de) |
JP (1) | JP2001502904A (de) |
AT (1) | ATE406452T1 (de) |
AU (1) | AU4712497A (de) |
DE (1) | DE69738944D1 (de) |
GB (2) | GB9621679D0 (de) |
WO (1) | WO1998017817A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1076715B1 (de) | 1998-05-13 | 2007-07-18 | Genetix Pharmaceuticals Inc. | Lentivirale Verpackungszellen |
CA2331782A1 (en) | 1998-06-24 | 1999-12-29 | Musc Foundation For Research Development | Tissue-specific and target rna-specific ribozymes |
CA2365901A1 (en) | 1999-04-14 | 2000-10-19 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
US6271359B1 (en) | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
WO2001036614A2 (de) | 1999-11-16 | 2001-05-25 | Geneart Gmbh Gessellschaft Für Angewandte Biotechnologie | Das genom des hiv-1 intersubtyps (c/b') und seine anwendungen |
EP1702983A3 (de) | 2000-04-13 | 2007-01-10 | Medical University of South Carolina | Gewebespezifische und pathogenspezifische giftige Verbindungen, Ribozyme, DNAzyme und Antisenseolinukleotide sowie Anwendungen dafür |
US20120294889A1 (en) * | 2010-11-12 | 2012-11-22 | Paxvax, Inc. | Chimeric Flavivirus Vaccines |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5306631A (en) * | 1987-08-21 | 1994-04-26 | University Of Colorado Foundation, Inc. | Compositions and method for inhibition of HIV production |
US6544771B1 (en) * | 1987-12-11 | 2003-04-08 | Cell Genesys, Inc. | Retroviral gene therapy vectors and therapeutic methods based thereon |
CA2109579A1 (en) * | 1991-05-29 | 1992-12-10 | Julianna Lisziewicz | Eukaryotic expression vectors with regulation of rna processing |
AU2419595A (en) * | 1994-05-10 | 1995-11-29 | Hisamitsu Pharmaceutical Co., Inc. | Recombinant human immunodeficiency virus vector and process for producing the same |
-
1996
- 1996-10-17 GB GBGB9621679.1A patent/GB9621679D0/en active Pending
-
1997
- 1997-10-17 GB GB9904143A patent/GB2331989B/en not_active Expired - Lifetime
- 1997-10-17 DE DE69738944T patent/DE69738944D1/de not_active Expired - Lifetime
- 1997-10-17 US US09/254,529 patent/US20020141978A1/en not_active Abandoned
- 1997-10-17 AT AT97909438T patent/ATE406452T1/de active
- 1997-10-17 EP EP97909438A patent/EP0931157B1/de not_active Expired - Lifetime
- 1997-10-17 AU AU47124/97A patent/AU4712497A/en not_active Abandoned
- 1997-10-17 JP JP10519088A patent/JP2001502904A/ja active Pending
- 1997-10-17 WO PCT/GB1997/002859 patent/WO1998017817A1/en active IP Right Grant
-
2005
- 2005-05-27 US US11/139,766 patent/US20060024279A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20020141978A1 (en) | 2002-10-03 |
WO1998017817A1 (en) | 1998-04-30 |
AU4712497A (en) | 1998-05-15 |
DE69738944D1 (de) | 2008-10-09 |
GB9904143D0 (en) | 1999-04-14 |
EP0931157B1 (de) | 2008-08-27 |
GB9621679D0 (en) | 1996-12-11 |
EP0931157A1 (de) | 1999-07-28 |
GB2331989A (en) | 1999-06-09 |
GB2331989B (en) | 2000-09-27 |
US20060024279A1 (en) | 2006-02-02 |
JP2001502904A (ja) | 2001-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Lavrentieva et al. | High polymorphism level of genomic sequences flanking insertion sites of human endogenous retroviral long terminal repeats | |
DE69534733D1 (de) | NEUARTIGE AUF p53 ANSPRECHENDE GENE | |
Ling et al. | The solitary long terminal repeats of ERV-9 endogenous retrovirus are conserved during primate evolution and possess enhancer activities in embryonic and hematopoietic cells | |
WO2001071042A3 (en) | Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof | |
NO20001497D0 (no) | Ekspresjon av endogene gener ved ikke-homolog rekombinasjon av en vektorkonstrukt med cellulært DNA | |
EP0385558A3 (de) | Materialien und Verfahren für "genome walking" | |
Klasens et al. | Inhibition of polyadenylation by stable RNA secondary structure | |
WO2003008575A3 (en) | Dna sequences for regulating transcription | |
ATE406452T1 (de) | Retrovirale vektoren | |
ATE91715T1 (de) | Genexpressionssystem. | |
ATE427959T1 (de) | Gereinigtes sr-p70 protein | |
ATE272711T1 (de) | Neuartige expressionsvektoren | |
DE69323199D1 (de) | Gen für die ataxia-telangiectasia komplementationsgruppe d | |
Tajima et al. | Mutant tax protein from bovine leukemia virus with enhanced ability to activate the expression of c-fos | |
DE68912228D1 (de) | Verfahren für die Rettung von DNS und für den Nachweis von Mutationen in Markiergenen. | |
SE8604636L (sv) | Sett att uttrycka gener med hjelp av bacillus brevis | |
ATE72837T1 (de) | Vielfach amplifizierbare vektoren fuer hohe expression exogener dns. | |
Mischiati et al. | Characterization of a major histocompatibility complex class II X-box-binding protein enhancing tat-induced transcription directed by the human immunodeficiency virus type 1 long terminal repeat | |
ATE259421T1 (de) | Dna-virus-vektoren und verfahren zu ihrer herstellung | |
CA2289907A1 (en) | Eukaryotic and retroviral antisense initiator elements | |
Lembo et al. | Trans-activation of the mouse cytomegalovirus immediate early gene enhancer by ras oncogenes | |
Peberdy | Genetic engineering in relation to enzymes. | |
DK561889A (da) | Ekspressionsforstaerker samt anvendelse heraf til forhoejelse af udbyttet ved ekspression af rekombinante gener | |
EP0962533A3 (de) | Auf Zucker reagierende Enhancer-Sequenzen aus alpha-Amylasegenen | |
ATE250670T1 (de) | Vektor, enthält ein bei arn-polymerase-iii transcriptes virus-gen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0931157 Country of ref document: EP |