ATE405660T1 - Verfahren zur insulinproduktion in pflanzen - Google Patents

Verfahren zur insulinproduktion in pflanzen

Info

Publication number: ATE405660T1
Authority: AT; Austria
Prior art keywords: plants; insulin production; insulin; production
Prior art date: 2003-06-17

Application number

AT04737835T

Other languages

English (en)

Inventor

Maurice Moloney

Joseph Boothe

Richard Keon

Cory Nykiforuk

Rooijen Gijs Van

Original Assignee

Sembiosys Genetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-17

Filing date

2004-06-17

Publication date

2008-09-15

2004-06-17 Application filed by Sembiosys Genetics Inc filed Critical Sembiosys Genetics Inc

2008-09-15 Application granted granted Critical

2008-09-15 Publication of ATE405660T1 publication Critical patent/ATE405660T1/de

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Diabetes (AREA)
Microbiology (AREA)
Pharmacology & Pharmacy (AREA)
Botany (AREA)
Developmental Biology & Embryology (AREA)
Environmental Sciences (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT04737835T 2003-06-17 2004-06-17 Verfahren zur insulinproduktion in pflanzen ATE405660T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47881803P	2003-06-17	2003-06-17
US54953904P	2004-03-04	2004-03-04

Publications (1)

Publication Number	Publication Date
ATE405660T1 true ATE405660T1 (de)	2008-09-15

Family

ID=33555509

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04737835T ATE405660T1 (de)	2003-06-17	2004-06-17	Verfahren zur insulinproduktion in pflanzen

Country Status (24)

Country	Link
US (2)	US7547821B2 (de)
EP (2)	EP1633876B1 (de)
JP (2)	JP4864701B2 (de)
KR (1)	KR101216762B1 (de)
CN (1)	CN1836047B (de)
AR (1)	AR044803A1 (de)
AT (1)	ATE405660T1 (de)
AU (1)	AU2004247762B2 (de)
BR (1)	BRPI0411479A (de)
CA (1)	CA2528741A1 (de)
CY (1)	CY1108477T1 (de)
DE (1)	DE602004015980D1 (de)
DK (1)	DK1633876T3 (de)
EA (1)	EA014887B1 (de)
ES (1)	ES2313018T3 (de)
HK (1)	HK1088037A1 (de)
IL (1)	IL172469A (de)
MX (1)	MXPA05013723A (de)
NO (1)	NO20055885L (de)
NZ (1)	NZ544522A (de)
PL (1)	PL1633876T3 (de)
PT (1)	PT1633876E (de)
TW (1)	TWI345587B (de)
WO (1)	WO2004111244A2 (de)

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EP2074140B8 (de)	2006-10-04	2015-10-28	Case Western Reserve University	Fibrillationsresistentes insulin und insulinanaloga
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US9200053B2 (en)	2008-07-31	2015-12-01	Case Western Reserve University	Insulin analogues containing penta-fluoro-Phenylalanine at position B24
CN101736029B (zh) *	2008-11-21	2013-01-02	复旦大学	一种利用植物油体蛋白表达系统生产人胰岛素样生长因子-i的方法
US8399407B2 (en) *	2009-09-17	2013-03-19	Case Western Reserve University	Non-standard insulin analogues
SG181527A1 (en)	2009-12-11	2012-07-30	Univ Case Western Reserve	Insulin analogues with chlorinated amino acids
CN102268451B (zh) *	2010-06-01	2014-03-12	安胜军	一种含有人胰岛素基因的表达载体及其构建方法与应用
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US9006176B2 (en) *	2011-10-18	2015-04-14	AmideBio LLC	Chemically and thermodynamically stable insulin analogues and improved methods for their production
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WO2014172488A2 (en)	2013-04-17	2014-10-23	AmideBio LLC	Chemically and thermodynamically stable insulin analogues and improved methods for their production
KR101625746B1 (ko)	2013-09-23	2016-05-31	순천대학교 산학협력단	프로미니인슐린 재조합 단백질이 발현된 형질전환 식물 및 이의 제조방법
JP6829928B2 (ja)	2014-10-06	2021-02-17	ケースウェスタンリザーブユニバーシティＣａｓｅＷｅｓｔｅｒｎＲｅｓｅｒｖｅＵｎｉｖｅｒｓｉｔｙ	二相性単鎖インスリン類似体
US20220096607A1 (en) *	2015-04-09	2022-03-31	Kinetiq Therapeutics, Llc	Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
HUE060149T2 (hu)	2016-12-16	2023-02-28	Novo Nordisk As	Inzulint tartalmazó gyógyászati készítmények
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JP2021513330A (ja) *	2018-02-09	2021-05-27	江蘇恒瑞医薬股▲ふん▼有限公司	ヒトインスリンアナログのコドン最適化前駆体遺伝子およびシグナルペプチド遺伝子
CN114144426A (zh) *	2019-04-19	2022-03-04	印地安纳大学理事会	餐时或基础胰岛素类似物通过内部二硒桥的稳定化
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EP4190905A1 (de)	2021-12-01	2023-06-07	Core Biogenesis	Verfahren zur reinigung von rekombinanten proteinen unter verwendung von ölkörperproteinen

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2004
- 2004-06-17 DE DE602004015980T patent/DE602004015980D1/de not_active Expired - Lifetime
- 2004-06-17 CA CA002528741A patent/CA2528741A1/en not_active Abandoned
- 2004-06-17 MX MXPA05013723A patent/MXPA05013723A/es active IP Right Grant
- 2004-06-17 NZ NZ544522A patent/NZ544522A/en not_active IP Right Cessation
- 2004-06-17 TW TW093117421A patent/TWI345587B/zh not_active IP Right Cessation
- 2004-06-17 CN CN2004800236023A patent/CN1836047B/zh not_active Expired - Fee Related
- 2004-06-17 DK DK04737835T patent/DK1633876T3/da active
- 2004-06-17 US US10/869,040 patent/US7547821B2/en not_active Expired - Fee Related
- 2004-06-17 PL PL04737835T patent/PL1633876T3/pl unknown
- 2004-06-17 JP JP2006515598A patent/JP4864701B2/ja not_active Expired - Fee Related
- 2004-06-17 EA EA200600050A patent/EA014887B1/ru not_active IP Right Cessation
- 2004-06-17 EP EP04737835A patent/EP1633876B1/de not_active Expired - Lifetime
- 2004-06-17 WO PCT/CA2004/000896 patent/WO2004111244A2/en active IP Right Grant
- 2004-06-17 AR ARP040102114A patent/AR044803A1/es active IP Right Grant
- 2004-06-17 AU AU2004247762A patent/AU2004247762B2/en not_active Ceased
- 2004-06-17 ES ES04737835T patent/ES2313018T3/es not_active Expired - Lifetime
- 2004-06-17 AT AT04737835T patent/ATE405660T1/de active
- 2004-06-17 EP EP08007159A patent/EP1959017A1/de not_active Withdrawn
- 2004-06-17 PT PT04737835T patent/PT1633876E/pt unknown
- 2004-06-17 BR BRPI0411479-5A patent/BRPI0411479A/pt not_active IP Right Cessation
2005
- 2005-12-08 IL IL172469A patent/IL172469A/en not_active IP Right Cessation
- 2005-12-12 NO NO20055885A patent/NO20055885L/no not_active Application Discontinuation
- 2005-12-16 KR KR1020057024281A patent/KR101216762B1/ko not_active Expired - Fee Related
2006
- 2006-08-18 HK HK06109198.5A patent/HK1088037A1/xx not_active IP Right Cessation
2008
- 2008-11-03 CY CY20081101246T patent/CY1108477T1/el unknown
2009
- 2009-05-12 US US12/464,207 patent/US20090282583A1/en not_active Abandoned
2011
- 2011-06-03 JP JP2011124794A patent/JP2011200251A/ja active Pending

Also Published As

Publication number	Publication date
WO2004111244A3 (en)	2005-02-03
CN1836047B (zh)	2010-12-22
EA014887B1 (ru)	2011-02-28
TW200510529A (en)	2005-03-16
IL172469A0 (en)	2006-04-10
TWI345587B (en)	2011-07-21
HK1088037A1 (en)	2006-10-27
CA2528741A1 (en)	2004-12-23
EP1633876A2 (de)	2006-03-15
KR20060052705A (ko)	2006-05-19
DK1633876T3 (da)	2008-12-08
NZ544522A (en)	2008-03-28
KR101216762B1 (ko)	2013-01-02
AU2004247762A1 (en)	2004-12-23
AU2004247762B2 (en)	2010-05-27
ES2313018T3 (es)	2009-03-01
NO20055885L (no)	2006-01-17
US20050039235A1 (en)	2005-02-17
BRPI0411479A (pt)	2006-07-25
MXPA05013723A (es)	2006-03-13
AR044803A1 (es)	2005-10-05
CN1836047A (zh)	2006-09-20
DE602004015980D1 (de)	2008-10-02
EP1633876B1 (de)	2008-08-20
EP1959017A1 (de)	2008-08-20
JP4864701B2 (ja)	2012-02-01
PT1633876E (pt)	2008-11-03
CY1108477T1 (el)	2014-04-09
US20090282583A1 (en)	2009-11-12
PL1633876T3 (pl)	2009-01-30
JP2007523611A (ja)	2007-08-23
WO2004111244A2 (en)	2004-12-23
JP2011200251A (ja)	2011-10-13
IL172469A (en)	2011-08-31
EA200600050A1 (ru)	2006-06-30
US7547821B2 (en)	2009-06-16

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