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ATE389881T1 - Detektion von kleinen molekülen mit piezo- elektrischem sensor - Google Patents

Detektion von kleinen molekülen mit piezo- elektrischem sensor

Info

Publication number
ATE389881T1
ATE389881T1 AT00901308T AT00901308T ATE389881T1 AT E389881 T1 ATE389881 T1 AT E389881T1 AT 00901308 T AT00901308 T AT 00901308T AT 00901308 T AT00901308 T AT 00901308T AT E389881 T1 ATE389881 T1 AT E389881T1
Authority
AT
Austria
Prior art keywords
antigen
binding portion
altered
protein
piezo
Prior art date
Application number
AT00901308T
Other languages
English (en)
Inventor
Itamar Willner
Zelig Eshhar
Original Assignee
Yissum Res Dev Co
Yeda Res & Dev
Biosensor Applic Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co, Yeda Res & Dev, Biosensor Applic Sweden Ab filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE389881T1 publication Critical patent/ATE389881T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measurement Of Length, Angles, Or The Like Using Electric Or Magnetic Means (AREA)
  • Piezo-Electric Transducers For Audible Bands (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Fluid Pressure (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
AT00901308T 1999-01-25 2000-01-25 Detektion von kleinen molekülen mit piezo- elektrischem sensor ATE389881T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12821299A IL128212A (en) 1999-01-25 1999-01-25 Detection of small molecules by use of a piezoelectric sensor

Publications (1)

Publication Number Publication Date
ATE389881T1 true ATE389881T1 (de) 2008-04-15

Family

ID=11072413

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00901308T ATE389881T1 (de) 1999-01-25 2000-01-25 Detektion von kleinen molekülen mit piezo- elektrischem sensor

Country Status (7)

Country Link
US (1) US7135295B1 (de)
EP (1) EP1145006B1 (de)
AT (1) ATE389881T1 (de)
AU (1) AU2126400A (de)
DE (1) DE60038363T2 (de)
IL (1) IL128212A (de)
WO (1) WO2000043774A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4663318B2 (ja) * 2002-06-19 2011-04-06 バイオセンサー、アプリケーションズ、スエーデン、アクチボラグ 置換による分析物検出に有用な固体担体上の被覆された金属表面
CN1675549A (zh) * 2002-06-19 2005-09-28 瑞典生物传感器应用股份公司 用于置换反应的固体载体上的涂覆的金属表面
FI20030615A0 (fi) * 2003-04-24 2003-04-24 Marko Virta Nanopartikkeli bioaffiniteettimäärityksiin
CN1902491A (zh) * 2003-11-20 2007-01-24 瑞典生物传感器应用股份公司 至少两种不同的、特异于预定抗原的抗体混合物和该混合物的用途
US8349604B2 (en) * 2006-06-15 2013-01-08 University Of South Florida Nano-based device for detection of disease biomarkers and other target molecules
US20080100279A1 (en) * 2006-06-15 2008-05-01 University Of South Florida Nano-Based Device for Detection of Disease Biomarkers and Other Target Molecules
CN101595387B (zh) * 2006-12-13 2014-01-29 生物传感器应用国际有限公司 在测试体积中测试抗原的连续可重复方法
EP2102659B1 (de) * 2006-12-13 2012-10-31 Biosensor Applications Sweden AB (Publ) Ständig wiederholbares verfahren zum nachweis von antigenen in einem testvolumen
EP2630479B1 (de) 2010-10-20 2020-04-08 Qorvo US, Inc. Vorrichtung und verfahren zur messung einer bindungskinetik und einer konzentration mit einem resonanzsensor
US8771402B2 (en) * 2011-06-14 2014-07-08 Ut-Battelle, Llc Membrane based apparatus for measurement of volatile particles
KR20140097115A (ko) * 2011-08-26 2014-08-06 아비아나 몰레큘라 테크놀로지스 엘엘씨 현장 진단용 바이오 코팅 압전 바이오센서 플랫폼
EP3194962B1 (de) 2014-09-15 2019-04-03 Qorvo Us, Inc. Massendetektion durch redox-kupplung
CN104407150B (zh) * 2014-11-12 2016-03-30 浙江大学 用于2,4,6-tnt检测的生物纳米传感器制备方法
FR3032792B1 (fr) * 2015-02-13 2017-03-24 Inst De Rech Pour Le Dev (Ird) Dispositif de captage d'au moins une espece chimique comprenant un capteur chimique et procede de fabrication d'un tel capteur chimique
JP7437000B2 (ja) * 2016-07-01 2024-02-22 パラクライン セラピューティクス アーベー Ｐｄｇｆ－ｃｃの阻害のための方法および組成物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242096A (en) 1977-11-14 1980-12-30 Minnesota Mining And Manufacturing Company Immunoassay for antigens
US4236893A (en) 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4314821A (en) * 1979-04-09 1982-02-09 Minnesota Mining And Manufacturing Company Sandwich immunoassay using piezoelectric oscillator
US4735906A (en) 1984-11-28 1988-04-05 Texas A&M University Sensor having piezoelectric crystal for microgravimetric immunoassays
US4999284A (en) * 1988-04-06 1991-03-12 E. I. Du Pont De Nemours And Company Enzymatically amplified piezoelectric specific binding assay
JPH01269485A (ja) * 1988-04-20 1989-10-26 Matsushita Electric Ind Co Ltd モノクローナル抗体産生細胞ラインおよびモノクローナル抗体
JPH01269488A (ja) * 1988-04-20 1989-10-26 Matsushita Electric Ind Co Ltd モノクローナル抗体産生細胞ラインおよびモノクローナル抗体
JPH05500715A (ja) 1989-10-04 1993-02-12 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー バイオセンサーの表面上の生物学的標的複合体のアツセイ方法
US5179028A (en) * 1990-04-20 1993-01-12 Hughes Aircraft Company Antibody coated crystal chemical sensor
IL114692A (en) * 1995-07-21 1999-10-28 Yissum Res Dev Co Determination of an analyte in a liquid medium
AU8626198A (en) * 1997-06-12 1998-12-30 Biosensor Applications Sweden Ab Apparatus, system and method for the detection of an analyte in air

Also Published As

Publication number Publication date
EP1145006B1 (de) 2008-03-19
WO2000043774A3 (en) 2001-03-01
EP1145006A2 (de) 2001-10-17
DE60038363D1 (de) 2008-04-30
WO2000043774A2 (en) 2000-07-27
AU2126400A (en) 2000-08-07
IL128212A0 (en) 1999-11-30
US7135295B1 (en) 2006-11-14
IL128212A (en) 2004-06-20
DE60038363T2 (de) 2009-04-23

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Legal Events

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