[go: up one dir, main page]

ATE384121T1 - Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen - Google Patents

Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen

Info

Publication number
ATE384121T1
ATE384121T1 AT01963871T AT01963871T ATE384121T1 AT E384121 T1 ATE384121 T1 AT E384121T1 AT 01963871 T AT01963871 T AT 01963871T AT 01963871 T AT01963871 T AT 01963871T AT E384121 T1 ATE384121 T1 AT E384121T1
Authority
AT
Austria
Prior art keywords
human lung
lung mast
cells
mast cells
cultivation
Prior art date
Application number
AT01963871T
Other languages
English (en)
Inventor
Edward Schulman
Original Assignee
Philadelphia Health & Educatio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philadelphia Health & Educatio filed Critical Philadelphia Health & Educatio
Application granted granted Critical
Publication of ATE384121T1 publication Critical patent/ATE384121T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0642—Granulocytes, e.g. basopils, eosinophils, neutrophils, mast cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0688—Cells from the lungs or the respiratory tract
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
AT01963871T 2000-08-08 2001-08-08 Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen ATE384121T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22380700P 2000-08-08 2000-08-08

Publications (1)

Publication Number Publication Date
ATE384121T1 true ATE384121T1 (de) 2008-02-15

Family

ID=22838046

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01963871T ATE384121T1 (de) 2000-08-08 2001-08-08 Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen

Country Status (8)

Country Link
US (2) US7524679B2 (de)
EP (1) EP1315793B1 (de)
JP (1) JP2004505626A (de)
AT (1) ATE384121T1 (de)
AU (2) AU2001284786B2 (de)
CA (1) CA2419062A1 (de)
DE (1) DE60132466T2 (de)
WO (1) WO2002012448A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050112622A1 (en) * 2003-08-11 2005-05-26 Ring Brian Z. Reagents and methods for use in cancer diagnosis, classification and therapy
US20080131916A1 (en) * 2004-08-10 2008-06-05 Ring Brian Z Reagents and Methods For Use In Cancer Diagnosis, Classification and Therapy
WO2009135001A2 (en) * 2008-04-30 2009-11-05 University Of Pittsburgh- Commonwealth System Of Higher Education Methods and compositions for regulating th2 and th17 responses
CN108865975B (zh) * 2018-07-16 2021-11-23 浙江普罗亭健康科技有限公司 斑块组织消化试剂盒及其应用
CN109852575A (zh) * 2018-12-27 2019-06-07 河北生命原点生物科技有限公司 一种肺泡ⅱ型细胞的分离方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4117054B2 (ja) * 1998-01-14 2008-07-09 信 川井 抗体及びその製法、この抗体を産生する融合細胞及びその製法、並びにこの抗体に認識される抗原蛋白質
US6080747A (en) * 1999-03-05 2000-06-27 Hughes Institute JAK-3 inhibitors for treating allergic disorders
JP4710846B2 (ja) * 2007-02-21 2011-06-29 トヨタ自動車株式会社 内燃機関の排気浄化装置
DE102008036127A1 (de) * 2008-08-01 2010-02-04 Emitec Gesellschaft Für Emissionstechnologie Mbh Verfahren zum Betrieb einer Abgasanlage mit Lambda-Regelung
US8474247B2 (en) * 2009-03-18 2013-07-02 GM Global Technology Operations LLC Particulate filter regeneration post-injection fuel rate control

Also Published As

Publication number Publication date
JP2004505626A (ja) 2004-02-26
AU2001284786B2 (en) 2006-04-27
WO2002012448A1 (en) 2002-02-14
CA2419062A1 (en) 2002-02-14
EP1315793A1 (de) 2003-06-04
US7524679B2 (en) 2009-04-28
US20040014208A1 (en) 2004-01-22
AU8478601A (en) 2002-02-18
EP1315793B1 (de) 2008-01-16
DE60132466D1 (de) 2008-03-06
US20090176880A1 (en) 2009-07-09
EP1315793A4 (de) 2004-07-14
DE60132466T2 (de) 2008-12-24

Similar Documents

Publication Publication Date Title
AR000921A1 (es) Composicion como medio de cultivo para soportar el crecimiento de poblaciones celulares. metodo in vitro para sostener el crecimiento in vitro dede celulas eucarioticas, respectivamente para in vitro incrementar las propiedades del tejido submucoso para cultivar celulas islote o analizar in
DE69533223D1 (de) Zusammensetzungen und verfahren zur stimulierung der proliferation und der differenzierung von menschlichen fetalen und erwachsenen pankreatischen zellen ex vivo
DE60139926D1 (de) Methode oder apparat zur kultivierung von zellen oder gewebe
WO2003065999A3 (en) Proliferated cell lines and uses thereof
WO2001036589A3 (en) Human ex vivo immune system
CA2244659A1 (en) Biological reactor for the cultivation of cells
WO2004076647A3 (en) Use of steady-state oxygen gradients to modulate animal cell functions
BR0210599A (pt) Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
IL160445A (en) Unit and process for carrying out high cell density fermentation
GB9308271D0 (en) Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
SE0201328D0 (sv) Hematopoietic differentiation of human embryonic stem cells
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
AU2369595A (en) In vitro growth of functional islets of langerhans and in vivo uses thereof
Souza et al. Regeneration of skin tissue promoted by mesenchymal stem cells seeded in nanostructured membrane
ATE225847T1 (de) Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen
RU2006146795A (ru) Композиция для стимулирования роста и регенерации клеток, а также способы ее получения
UA81398C2 (en) Keratinocytes which may be used as biologically active substances for the treatment of wounds
AU2003304250A1 (en) Method of isolating cells from umbilical cord
DE69635924D1 (de) Isolierung und züchtung von schwannzellen
DE69935999D1 (de) Methoden zur introduktion heterologer zellen in fische
ATE384121T1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
DE60310748D1 (de) Verfahren zur homogenen masskultivierung von t-lymphozyten
DE60120676D1 (de) Verfahren zur entwicklung von epithelialen stammzellen
DE602006014534D1 (de) Herstellung und verwendung von basalmembranpartikeln
ATE414141T1 (de) Verfahren zur kultivierung humaner chondrozyten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties