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ATE360081T1 - Guanylat-bindendes protein (gbp-1) als inhibitor der zellproliferation - Google Patents

Guanylat-bindendes protein (gbp-1) als inhibitor der zellproliferation

Info

Publication number
ATE360081T1
ATE360081T1 AT99941654T AT99941654T ATE360081T1 AT E360081 T1 ATE360081 T1 AT E360081T1 AT 99941654 T AT99941654 T AT 99941654T AT 99941654 T AT99941654 T AT 99941654T AT E360081 T1 ATE360081 T1 AT E360081T1
Authority
AT
Austria
Prior art keywords
gbp
binding protein
inhibitor
guanylate binding
cell proliferation
Prior art date
Application number
AT99941654T
Other languages
English (en)
Inventor
Michael Stuerzl
Emmanuelle Cornali
Original Assignee
Stuerzl Michael Prof Dr Rer Na
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stuerzl Michael Prof Dr Rer Na filed Critical Stuerzl Michael Prof Dr Rer Na
Application granted granted Critical
Publication of ATE360081T1 publication Critical patent/ATE360081T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99941654T 1998-08-26 1999-08-23 Guanylat-bindendes protein (gbp-1) als inhibitor der zellproliferation ATE360081T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199801081 1998-08-26
DKPA199801241 1998-10-01

Publications (1)

Publication Number Publication Date
ATE360081T1 true ATE360081T1 (de) 2007-05-15

Family

ID=26065193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99941654T ATE360081T1 (de) 1998-08-26 1999-08-23 Guanylat-bindendes protein (gbp-1) als inhibitor der zellproliferation

Country Status (10)

Country Link
US (2) US6894157B2 (de)
EP (2) EP1736547A1 (de)
JP (1) JP2002523104A (de)
AT (1) ATE360081T1 (de)
AU (1) AU5518499A (de)
CA (1) CA2340596A1 (de)
DE (1) DE69935862T2 (de)
DK (1) DK1108046T3 (de)
ES (1) ES2286893T3 (de)
WO (1) WO2000012737A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340596A1 (en) 1998-08-26 2000-03-09 Bavarian Nordic Research Institute A/S Guanylate binding protein (gbp-1) as inhibitor of cell proliferation and molecular marker for the determination of the stage of cellular differentiation
US7575924B2 (en) 2000-11-13 2009-08-18 Research Development Foundation Methods and compositions relating to improved lentiviral vectors and their applications
AU2002327412A1 (en) 2001-08-02 2003-02-17 Institut Clayton De La Recherche Methods and compositions relating to improved lentiviral vector production systems
CA2915676C (en) 2001-10-02 2017-06-06 Institut Clayton De La Recherche Restricted expression lentiviral vectors
JPWO2003054231A1 (ja) * 2001-12-13 2005-04-28 株式会社ジェノックス創薬研究所 アレルギー性疾患の検査方法
DE10260265A1 (de) * 2002-12-20 2004-07-01 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH ELISA Verfahren zum Nachweis von Guanylate Bindung Protein-1 (GBP-1)
JP5358583B2 (ja) * 2007-11-13 2013-12-04 フェニックス・バイオテクノロジー・インコーポレイテッド 強心配糖体を用いた癌の化学療法における治療応答の確率を求める方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833975A (en) * 1989-03-08 1998-11-10 Virogenetics Corporation Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence
US5256553A (en) * 1987-10-09 1993-10-26 Immunex Corporation Multiple promoter transforming retroviral vectors
US5328470A (en) * 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5804604A (en) 1989-12-21 1998-09-08 Biogen, Inc. Tat-derived transport polypeptides and fusion proteins
US5674980A (en) * 1989-12-21 1997-10-07 Biogen Inc Fusion protein comprising tat-derived transport moiety
US5871965A (en) 1996-10-25 1999-02-16 Incyte Pharmaceuticals, Inc. Guanylate binding proteins
US5856129A (en) * 1996-10-30 1999-01-05 Incyte Pharmaceuticals, Inc. DNA encoding a human purinoceptor
US5843665A (en) * 1996-10-31 1998-12-01 Incyte Pharmaceuticals, Inc. Human pyrophosphatase
US5824500A (en) * 1996-11-21 1998-10-20 Incyte Pharmaceuticals, Inc. Nucleic acid encoding novel human KDEL receptor
US5834242A (en) * 1997-05-01 1998-11-10 Incyte Pharmaceuticals, Inc. Human clathrin-associated protein
CA2340596A1 (en) 1998-08-26 2000-03-09 Bavarian Nordic Research Institute A/S Guanylate binding protein (gbp-1) as inhibitor of cell proliferation and molecular marker for the determination of the stage of cellular differentiation

Also Published As

Publication number Publication date
EP1108046B1 (de) 2007-04-18
WO2000012737A1 (en) 2000-03-09
US6894157B2 (en) 2005-05-17
DE69935862D1 (de) 2007-05-31
EP1108046A1 (de) 2001-06-20
DE69935862T2 (de) 2008-01-10
US20020115138A1 (en) 2002-08-22
JP2002523104A (ja) 2002-07-30
DK1108046T3 (da) 2007-09-17
EP1736547A1 (de) 2006-12-27
CA2340596A1 (en) 2000-03-09
US20060025362A1 (en) 2006-02-02
AU5518499A (en) 2000-03-21
ES2286893T3 (es) 2007-12-01

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