ATE350060T1 - Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthalten - Google Patents
Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthaltenInfo
- Publication number
- ATE350060T1 ATE350060T1 AT99938591T AT99938591T ATE350060T1 AT E350060 T1 ATE350060 T1 AT E350060T1 AT 99938591 T AT99938591 T AT 99938591T AT 99938591 T AT99938591 T AT 99938591T AT E350060 T1 ATE350060 T1 AT E350060T1
- Authority
- AT
- Austria
- Prior art keywords
- agents
- preventing
- active component
- receptor antibodies
- contain anti
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25179698 | 1998-08-24 | ||
| JP5430299 | 1999-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE350060T1 true ATE350060T1 (de) | 2007-01-15 |
Family
ID=26395047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99938591T ATE350060T1 (de) | 1998-08-24 | 1999-08-23 | Mittel zur vorbeugung oder behandlung von pankreatitis die anti-il-6 receptor antikörper als aktive komponente enthalten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8440196B1 (de) |
| EP (1) | EP1108435B1 (de) |
| JP (1) | JP4711507B2 (de) |
| AT (1) | ATE350060T1 (de) |
| AU (1) | AU757261B2 (de) |
| CA (1) | CA2341239C (de) |
| DE (1) | DE69934698T2 (de) |
| DK (1) | DK1108435T3 (de) |
| ES (1) | ES2276525T3 (de) |
| PT (1) | PT1108435E (de) |
| WO (1) | WO2000010607A1 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10324639A (ja) | 1997-03-21 | 1998-12-08 | Chugai Pharmaceut Co Ltd | Ｉｌ−６アンタゴニストを有効成分として含有する感作ｔ細胞関与疾患の予防・治療剤 |
| UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
| AU2003211991B2 (en) | 2002-02-14 | 2008-08-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing solution formulations |
| GB2401040A (en) * | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| JP4960096B2 (ja) * | 2003-09-22 | 2012-06-27 | ペントラコール ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｉｌ−６の生物学的効果を減じる化合物の使用 |
| EP3736295A1 (de) | 2004-03-24 | 2020-11-11 | Chugai Seiyaku Kabushiki Kaisha | Subtypen des humanisierten antikörpers gegen interleukin-6-rezeptor |
| AR048335A1 (es) | 2004-03-24 | 2006-04-19 | Chugai Pharmaceutical Co Ltd | Agentes terapeuticos para trastornos del oido interno que contienen un antagonista de il- 6 como un ingrediente activo |
| BRPI0617378B8 (pt) | 2005-10-14 | 2022-09-20 | Chugai Pharmaceutical Co Ltd | Uso de um inibidor de il-6 para produzir uma composição farmacêutica para suprimir dano a um ilhota transplantada depois do transplante de ilhota; e aperfeiçoar a viabilidade de uma ilhota em um transplante de ilhota |
| US8945558B2 (en) | 2005-10-21 | 2015-02-03 | Chugai Seiyaku Kabushiki Kaisha | Methods for treating myocardial infarction comprising administering an IL-6 inhibitor |
| AR057582A1 (es) | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
| CN101370521A (zh) | 2006-01-27 | 2009-02-18 | 学校法人庆应义塾 | 伴有脉络膜血管生成的疾病的治疗药 |
| EP2025346B1 (de) | 2006-04-07 | 2016-08-10 | Osaka University | Mittel zur förderung der muskelregeneration |
| US8080248B2 (en) | 2006-06-02 | 2011-12-20 | Regeneron Pharmaceuticals, Inc. | Method of treating rheumatoid arthritis with an IL-6R antibody |
| EP2374818B1 (de) | 2006-06-02 | 2012-12-19 | Regeneron Pharmaceuticals, Inc. | Antikörper mit hoher Affinität für den menschlichen IL-6-Rezeptor |
| US7919095B2 (en) | 2006-08-03 | 2011-04-05 | Vaccinex, Inc. | Anti-IL-6 monoclonal antibodies |
| JP2010095445A (ja) * | 2006-12-27 | 2010-04-30 | Tokyo Medical & Dental Univ | Ｉｌ−６アンタゴニストを有効成分とする炎症性筋疾患治療剤 |
| AU2008208321B2 (en) | 2007-01-23 | 2013-03-21 | Chugai Seiyaku Kabushiki Kaisha | Chronic rejection inhibitor |
| US9981415B2 (en) | 2007-09-10 | 2018-05-29 | Ehc Canada, Inc. | Method and apparatus for extrusion of thermoplastic handrail |
| WO2016201578A1 (en) | 2015-06-19 | 2016-12-22 | Ehc Canada, Inc. | Method and apparatus for extrusion of thermoplastic handrail |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| ES2564635T3 (es) | 2008-05-13 | 2016-03-28 | Novimmune Sa | Anticuerpos anti-IL-6/IL-6R y métodos de uso de los mismos |
| TWI528973B (zh) | 2008-06-05 | 2016-04-11 | Chugai Pharmaceutical Co Ltd | Nerve infiltration inhibitor |
| US8188235B2 (en) | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
| NZ755378A (en) | 2009-03-18 | 2022-07-29 | Resverlogix Corp | Novel quinazolinones and related compounds for use as anti-inflammatory agents |
| ES2821018T3 (es) | 2009-04-22 | 2021-04-23 | Resverlogix Corp | Nuevos agentes antiinflamatorios |
| SI2493922T1 (sl) | 2009-10-26 | 2017-06-30 | F. Hoffmann-La Roche Ag | Postopek za proizvodnjo glikoziliranega imunoglobulina |
| JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
| JP5904552B2 (ja) * | 2010-05-28 | 2016-04-13 | 国立研究開発法人国立がん研究センター | 膵癌治療剤 |
| SI2578231T1 (sl) | 2010-05-28 | 2023-01-31 | Chugai Seiyaku Kabushiki Kaisha | Okrepljen protitumorski T celični odzivnik |
| TWI603738B (zh) | 2010-11-08 | 2017-11-01 | 建南德克公司 | 皮下投予抗－ｉｌ－６受體抗體 |
| JPWO2012067150A1 (ja) * | 2010-11-16 | 2014-05-12 | 三菱化学株式会社 | Ｉｎｔｅｒｌｅｕｋｉｎ−６ｒｅｃｅｐｔｏｒｓｕｂｕｎｉｔｂｅｔａ蛋白質による脳梗塞の検査方法 |
| TWI589299B (zh) | 2011-10-11 | 2017-07-01 | 再生元醫藥公司 | 用於治療類風濕性關節炎之組成物及其使用方法 |
| JP6117915B2 (ja) | 2012-05-21 | 2017-04-19 | コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジーＫｏｒｅａ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｂｉｏｓｃｉｅｎｃｅ Ａｎｄ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ | ミゾコウジュの抽出物またはその分画物を有効成分として含む、ｓｔａｔ３媒介性疾患の予防または治療用医薬組成物 |
| BR112015032960B1 (pt) | 2013-07-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | imunoensaio suprimido por interferência para detectar anticorpos anti-fármaco em amostras de soro |
| US9017678B1 (en) | 2014-07-15 | 2015-04-28 | Kymab Limited | Method of treating rheumatoid arthritis using antibody to IL6R |
| JO3789B1 (ar) | 2015-03-13 | 2021-01-31 | Resverlogix Corp | التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة |
| RU2717807C2 (ru) | 2015-05-07 | 2020-03-25 | ИЭйчСи Канада, Инк. | Компактный поручень из композитного материала с улучшенными механическими характеристиками |
| EP3305325A4 (de) | 2015-06-04 | 2019-01-16 | National Center of Neurology and Psychiatry | Wirkstoff zur therapie von geisteskrankheiten mit il-6-hemmer als wirkstoff |
| WO2017147169A1 (en) | 2016-02-22 | 2017-08-31 | Ohio State Innovation Foundation | Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin a analogues or metabolites, and estradiol metabolites |
| US10980739B2 (en) | 2016-12-14 | 2021-04-20 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| CN117045784A (zh) | 2016-12-14 | 2023-11-14 | 比奥拉治疗股份有限公司 | 使用利用可摄入装置释放的il-12/il-23抑制剂治疗胃肠道疾病 |
| EP3596175A4 (de) | 2017-03-17 | 2021-01-13 | The Ohio State Innovation Foundation | Nanopartikel zur abgabe von chemopräventiven mitteln |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | 国立研究開発法人国立精神・神経医療研究センター | Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法 |
| WO2019078344A1 (ja) | 2017-10-20 | 2019-04-25 | 学校法人兵庫医科大学 | 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物 |
| US20210363233A1 (en) | 2018-06-20 | 2021-11-25 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| MX2021009242A (es) | 2019-01-31 | 2021-10-26 | Sanofi Biotechnology | Anticuerpo anti-receptor de il-6 para tratar la artritis juvenil idiopatica. |
| WO2020201362A2 (en) | 2019-04-02 | 2020-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| WO2024126805A1 (en) | 2022-12-15 | 2024-06-20 | Aarhus Universitet | Synthetic activation of multimeric transmembrane receptors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2898040B2 (ja) | 1990-01-26 | 1999-05-31 | 忠三 岸本 | ｇｐ１３０蛋白質に対する抗体 |
| US5210075A (en) | 1990-02-16 | 1993-05-11 | Tanabe Seiyaku Co., Ltd. | Interleukin 6 antagonist peptides |
| KR100249937B1 (ko) * | 1991-04-25 | 2000-04-01 | 나가야마 오사무 | 인간 인터루킨-6 수용체에 대한 재구성 인간 항체 |
| JPH05304986A (ja) | 1992-04-28 | 1993-11-19 | Tosoh Corp | ｇｐ１３０蛋白質に対するモノクロ−ナル抗体 |
| JP3525221B2 (ja) * | 1993-02-17 | 2004-05-10 | 味の素株式会社 | 免疫抑制剤 |
| EP0791359A4 (de) | 1994-10-21 | 2002-09-11 | Chugai Pharmaceutical Co Ltd | Heilmittel gegen von il-6 produktion verurschten krankheiten |
| IT1274350B (it) | 1994-12-06 | 1997-07-17 | Angeletti P Ist Richerche Bio | Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130 |
| IT1274782B (it) | 1994-12-14 | 1997-07-24 | Angeletti P Ist Richerche Bio | Metodo per selezionare superagonisti, antagonisti e superantagonisti di ormoni del cui complesso recettoriale fa parte gp 130 |
| AU6038196A (en) | 1995-06-07 | 1996-12-30 | Private Biologicals Corporation | Compositions and methods of treating il-6 associated disease s |
-
1999
- 1999-08-23 CA CA2341239A patent/CA2341239C/en not_active Expired - Fee Related
- 1999-08-23 PT PT99938591T patent/PT1108435E/pt unknown
- 1999-08-23 JP JP2000565927A patent/JP4711507B2/ja not_active Expired - Fee Related
- 1999-08-23 DE DE69934698T patent/DE69934698T2/de not_active Expired - Lifetime
- 1999-08-23 AT AT99938591T patent/ATE350060T1/de active
- 1999-08-23 DK DK99938591T patent/DK1108435T3/da active
- 1999-08-23 US US09/762,550 patent/US8440196B1/en not_active Expired - Fee Related
- 1999-08-23 ES ES99938591T patent/ES2276525T3/es not_active Expired - Lifetime
- 1999-08-23 WO PCT/JP1999/004533 patent/WO2000010607A1/ja active IP Right Grant
- 1999-08-23 EP EP99938591A patent/EP1108435B1/de not_active Expired - Lifetime
- 1999-08-23 AU AU53049/99A patent/AU757261B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69934698D1 (de) | 2007-02-15 |
| CA2341239C (en) | 2011-01-04 |
| DE69934698T2 (de) | 2007-10-04 |
| EP1108435A1 (de) | 2001-06-20 |
| EP1108435B1 (de) | 2007-01-03 |
| PT1108435E (pt) | 2007-04-30 |
| DK1108435T3 (da) | 2007-02-05 |
| US8440196B1 (en) | 2013-05-14 |
| AU757261B2 (en) | 2003-02-13 |
| ES2276525T3 (es) | 2007-06-16 |
| AU5304999A (en) | 2000-03-14 |
| WO2000010607A1 (fr) | 2000-03-02 |
| JP4711507B2 (ja) | 2011-06-29 |
| EP1108435A4 (de) | 2002-05-08 |
| CA2341239A1 (en) | 2000-03-02 |
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| UEP | Publication of translation of european patent specification |
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