ATE335748T1 - Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen - Google Patents

Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen

Info

Publication number: ATE335748T1
Authority: AT; Austria
Prior art keywords: thienopyrimidiindiones; sup; autoimmune diseases; modulating autoimmune; compounds
Prior art date: 2003-01-17

Application number

AT04702477T

Other languages

English (en)

Inventor

Simon David Guile

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-17

Filing date

2004-01-15

Publication date

2006-09-15

2004-01-15 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE335748T1 publication Critical patent/ATE335748T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT04702477T 2003-01-17 2004-01-15 Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen ATE335748T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE0300119A SE0300119D0 (sv)	2003-01-17	2003-01-17	Novel compounds

Publications (1)

Publication Number	Publication Date
ATE335748T1 true ATE335748T1 (de)	2006-09-15

Family

ID=20290154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04702477T ATE335748T1 (de)	2003-01-17	2004-01-15	Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen

Country Status (24)

Country	Link
US (2)	US7384951B2 (de)
EP (1)	EP1587812B1 (de)
JP (1)	JP4519121B2 (de)
KR (2)	KR20110125256A (de)
CN (1)	CN100334093C (de)
AT (1)	ATE335748T1 (de)
AU (1)	AU2004206012B2 (de)
BR (1)	BRPI0406801B8 (de)
CA (1)	CA2512441C (de)
DE (1)	DE602004001857T2 (de)
EG (1)	EG25613A (de)
ES (1)	ES2270337T3 (de)
HK (1)	HK1081959A1 (de)
IL (1)	IL169370A (de)
IS (1)	IS2376B (de)
MX (1)	MXPA05007496A (de)
NO (1)	NO333702B1 (de)
NZ (1)	NZ541217A (de)
PL (1)	PL214682B1 (de)
RU (1)	RU2331647C2 (de)
SE (1)	SE0300119D0 (de)
UA (1)	UA81788C2 (de)
WO (1)	WO2004065394A1 (de)
ZA (1)	ZA200505364B (de)

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GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
SE0300120D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
EP1587811A1 (de) *	2003-01-17	2005-10-26	AstraZeneca AB	Thienopyridazinone und deren verwendung zur modulierung von autoimmunerkrankungen
SI1696920T1 (sl)	2003-12-19	2015-02-27	Plexxikon Inc.	Spojine in postopki za razvoj modulatorjev ret
US7498342B2 (en)	2004-06-17	2009-03-03	Plexxikon, Inc.	Compounds modulating c-kit activity
CA2608733A1 (en)	2005-05-17	2007-02-01	Plexxikon, Inc.	Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors
HUE027370T2 (en)	2005-06-22	2016-10-28	Plexxikon Inc	Pyrrolo [2,3-b] pyridine derivatives as protein kinase inhibitors
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
WO2008079909A1 (en)	2006-12-21	2008-07-03	Plexxikon, Inc.	Pyrrolo [2,3-b] pyridines as kinase modulators
PE20081581A1 (es)	2006-12-21	2008-11-12	Plexxikon Inc	COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA
CA2673736A1 (en)	2006-12-21	2008-07-03	Plexxikon, Inc.	Compounds and methods for kinase modulation, and indications therefor
GB0713479D0 (en) *	2007-07-11	2007-08-22	Syngenta Participations Ag	Substituted aromatic heterocyclic compounds as fungicides
JP2010533729A (ja)	2007-07-17	2010-10-28	プレキシコン，インコーポレーテッド	キナーゼ調節のための化合物と方法、及びそのための適応
WO2010089580A1 (en)	2009-02-06	2010-08-12	Astrazeneca Ab	Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
BRPI1009372A2 (pt) *	2009-03-23	2016-05-31	Glenmark Pharmaceuticals Sa	compostos, composição farmacêutica e respectivos usos
SI2411395T1 (sl) *	2009-03-23	2013-07-31	Glenmark Pharmaceuticals S.A.	Furopirimidindionski derivati kot TRPA1 modulatorji
NZ594398A (en)	2009-04-03	2014-03-28	Plexxikon Inc	Propane-1-sulfonic acid (3-[5-(4-chloro-phenyl)-1h-pyrrol [2, 3-b] pyridine-3-carbonyl]-2,4-difluoro-phenyl} -amide compositions and uses thereof
US8329724B2 (en)	2009-08-03	2012-12-11	Hoffmann-La Roche Inc.	Process for the manufacture of pharmaceutically active compounds
NZ629615A (en)	2009-11-06	2016-01-29	Plexxikon Inc	Compounds and methods for kinase modulation, and indications therefor
BR112013020041B1 (pt)	2011-02-07	2021-11-23	Plexxikon, Inc	Compostos e composições para a modulação de quinases e uso dos mesmos
AR085279A1 (es)	2011-02-21	2013-09-18	Plexxikon Inc	Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
WO2013109972A2 (en)	2012-01-20	2013-07-25	Regents Of The University Of Minnesota	Therapeutic compounds
US10085987B2 (en)	2012-01-27	2018-10-02	Thomas Jefferson University	MCT protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds
US10022372B2 (en)	2013-04-19	2018-07-17	Thomas Jefferson University	Caveolin-1 related methods for treating glioblastoma with temozolomide
JP6434506B2 (ja) *	2013-10-21	2018-12-05	ジェノスコ	置換ピリミジン化合物およびｓｙｋ阻害剤としてのそれらの使用
WO2016118825A1 (en) *	2015-01-22	2016-07-28	The Scripps Research Institute	Heterocyclic inhibitors of monocarboxylate transporters
UY36586A (es) *	2015-03-26	2016-10-31	Bayer Pharma AG	Heterociclilmetiltienouracilos y uso de los mismos
KR101730536B1 (ko) *	2016-03-17	2017-05-02	주식회사 골프존	스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
KR101712836B1 (ko) *	2016-03-17	2017-03-22	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712838B1 (ko) *	2016-03-17	2017-03-07	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
TWI823932B (zh) *	2018-05-11	2023-12-01	中國大陸商迪哲（江蘇）醫藥有限公司	三唑并嘧啶化合物及其在治療癌症中之用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US738495A (en) *	1902-12-26	1903-09-08	William E Sherwood	Thill-coupling.
SE9702001D0 (sv) *	1997-05-28	1997-05-28	Astra Pharma Prod	Novel compounds
US6469014B1 (en) *	1997-05-28	2002-10-22	Astrazeneca Ab	Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
ID25628A (id)	1997-12-05	2000-10-19	Astrazeneca Uk Ltd	Senyawa-senyawa baru
US6232320B1 (en) *	1998-06-04	2001-05-15	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
WO2000012514A1 (en) *	1998-08-28	2000-03-09	Astrazeneca Ab	Novel compounds
DE60104677T2 (de) *	2000-05-04	2005-07-28	Astrazeneca Ab	THIENO[2,3-d]PYRIMIDINDIONE UND IHRE VERWENDUNG ALS PHARMAZEUTISCHE MITTEL
GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
SE0300120D0 (sv)	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
EP1587811A1 (de) *	2003-01-17	2005-10-26	AstraZeneca AB	Thienopyridazinone und deren verwendung zur modulierung von autoimmunerkrankungen

2003
- 2003-01-17 SE SE0300119A patent/SE0300119D0/xx unknown
2004
- 2004-01-15 EP EP04702477A patent/EP1587812B1/de not_active Expired - Lifetime
- 2004-01-15 CA CA2512441A patent/CA2512441C/en not_active Expired - Lifetime
- 2004-01-15 WO PCT/SE2004/000052 patent/WO2004065394A1/en active IP Right Grant
- 2004-01-15 PL PL378222A patent/PL214682B1/pl unknown
- 2004-01-15 DE DE602004001857T patent/DE602004001857T2/de not_active Expired - Lifetime
- 2004-01-15 NZ NZ541217A patent/NZ541217A/en not_active IP Right Cessation
- 2004-01-15 ES ES04702477T patent/ES2270337T3/es not_active Expired - Lifetime
- 2004-01-15 UA UAA200506377A patent/UA81788C2/uk unknown
- 2004-01-15 CN CNB2004800071073A patent/CN100334093C/zh not_active Expired - Fee Related
- 2004-01-15 BR BRPI0406801A patent/BRPI0406801B8/pt not_active IP Right Cessation
- 2004-01-15 KR KR1020117022785A patent/KR20110125256A/ko not_active Application Discontinuation
- 2004-01-15 JP JP2006500750A patent/JP4519121B2/ja not_active Expired - Fee Related
- 2004-01-15 US US10/542,197 patent/US7384951B2/en not_active Expired - Lifetime
- 2004-01-15 RU RU2005121494/04A patent/RU2331647C2/ru not_active IP Right Cessation
- 2004-01-15 MX MXPA05007496A patent/MXPA05007496A/es active IP Right Grant
- 2004-01-15 AT AT04702477T patent/ATE335748T1/de not_active IP Right Cessation
- 2004-01-15 AU AU2004206012A patent/AU2004206012B2/en not_active Ceased
- 2004-01-15 KR KR1020057013126A patent/KR101107486B1/ko active IP Right Grant
2005
- 2005-06-23 IL IL169370A patent/IL169370A/en active IP Right Grant
- 2005-07-01 ZA ZA2005/05364A patent/ZA200505364B/en unknown
- 2005-07-12 EG EGNA2005000380 patent/EG25613A/xx active
- 2005-07-29 IS IS7965A patent/IS2376B/is unknown
- 2005-08-15 NO NO20053826A patent/NO333702B1/no not_active IP Right Cessation
2006
- 2006-02-17 HK HK06102161A patent/HK1081959A1/xx not_active IP Right Cessation
2008
- 2008-05-05 US US12/115,171 patent/US20080214579A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2512441A1 (en)	2004-08-05
BRPI0406801B1 (pt)	2018-04-03
EP1587812B1 (de)	2006-08-09
NO20053826D0 (no)	2005-08-15
RU2331647C2 (ru)	2008-08-20
CN1761672A (zh)	2006-04-19
IL169370A0 (en)	2007-07-04
CA2512441C (en)	2012-01-03
RU2005121494A (ru)	2006-02-10
NZ541217A (en)	2008-05-30
JP2006516974A (ja)	2006-07-13
US7384951B2 (en)	2008-06-10
IL169370A (en)	2011-05-31
US20080214579A1 (en)	2008-09-04
AU2004206012B2 (en)	2007-06-14
PL378222A1 (pl)	2006-03-20
PL214682B1 (pl)	2013-09-30
DE602004001857T2 (de)	2007-05-24
KR101107486B1 (ko)	2012-01-19
DE602004001857D1 (de)	2006-09-21
HK1081959A1 (en)	2006-05-26
UA81788C2 (uk)	2008-02-11
IS7965A (is)	2005-07-29
US20060052400A1 (en)	2006-03-09
JP4519121B2 (ja)	2010-08-04
KR20050092760A (ko)	2005-09-22
BRPI0406801B8 (pt)	2021-05-25
EG25613A (en)	2012-03-22
ES2270337T3 (es)	2007-04-01
IS2376B (is)	2008-07-15
KR20110125256A (ko)	2011-11-18
SE0300119D0 (sv)	2003-01-17
NO20053826L (no)	2005-10-17
ZA200505364B (en)	2006-09-27
EP1587812A1 (de)	2005-10-26
AU2004206012A1 (en)	2004-08-05
BRPI0406801A (pt)	2006-01-17
NO333702B1 (no)	2013-08-26
WO2004065394A1 (en)	2004-08-05
CN100334093C (zh)	2007-08-29
MXPA05007496A (es)	2005-09-21

Publication	Publication Date	Title
ATE335748T1 (de)	2006-09-15	Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen
IS6520A (is)	2002-08-22	Ný efnasambönd
IS6658A (is)	2002-12-17	Ný efnasambönd
SE0302139D0 (sv)	2003-07-28	Novel compounds
ATE433447T1 (de)	2009-06-15	Pyrimiidinverbindungen
SE0301700D0 (sv)	2003-06-10	Novel compounds
SE0202133D0 (sv)	2002-07-08	Novel compounds
SE0300480D0 (sv)	2003-02-21	Novel compounds
SE0103836D0 (sv)	2001-11-16	Novel compounds
AU2003228770A8 (en)	2003-11-11	Substituted pyrazolopyrimidines
EA200401526A1 (ru)	2005-04-28	Новые соединения и их применение
TW200604197A (en)	2006-02-01	New compounds
SE0101038D0 (sv)	2001-03-23	Novel compounds
EA200701856A1 (ru)	2008-02-28	Тетрагидропиридоазепин-8-оны и родственные соединения для лечения шизофрении
SE0303280D0 (sv)	2003-12-05	Novel compounds
GB0120461D0 (en)	2001-10-17	Novel compounds
ATE497967T1 (de)	2011-02-15	Interzelluläre kommunikation erleichternden verbindungen und deren medizinischen verwendungen
SE0401763D0 (sv)	2004-07-05	Compounds
SE9902551D0 (sv)	1999-07-02	Novel compounds
EA200600992A1 (ru)	2006-10-27	Амиды тиазолидинона, амиды тиазолидинкарбоновой кислоты, способы их получения и их применение
SE0303090D0 (sv)	2003-11-20	Novel compounds
SE0302755D0 (sv)	2003-10-17	Novel compounds
SE0202692D0 (sv)	2002-09-11	Compounds
IL172538A0 (en)	2006-04-10	Depsipeptide compounds, pharmaceutical compositions containing the same and processes for the preparation thereof
MXPA05007495A (es)	2005-09-21	Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.

Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties