ATE327232T1 - Heterozyklylalkylindole oder -azaindole als 5- hydroxytryptamine-6 liganden - Google Patents
Heterozyklylalkylindole oder -azaindole als 5- hydroxytryptamine-6 ligandenInfo
- Publication number
- ATE327232T1 ATE327232T1 AT01993251T AT01993251T ATE327232T1 AT E327232 T1 ATE327232 T1 AT E327232T1 AT 01993251 T AT01993251 T AT 01993251T AT 01993251 T AT01993251 T AT 01993251T AT E327232 T1 ATE327232 T1 AT E327232T1
- Authority
- AT
- Austria
- Prior art keywords
- heterocyclylalkylindols
- azaindols
- hydroxytryptamine
- ligands
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25768400P | 2000-12-22 | 2000-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE327232T1 true ATE327232T1 (de) | 2006-06-15 |
Family
ID=22977310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01993251T ATE327232T1 (de) | 2000-12-22 | 2001-12-11 | Heterozyklylalkylindole oder -azaindole als 5- hydroxytryptamine-6 liganden |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6613781B2 (de) |
| EP (1) | EP1355900B1 (de) |
| JP (1) | JP2004520325A (de) |
| KR (1) | KR20030062440A (de) |
| CN (1) | CN1492863A (de) |
| AR (1) | AR034284A1 (de) |
| AT (1) | ATE327232T1 (de) |
| BR (1) | BR0116481A (de) |
| CA (1) | CA2432661A1 (de) |
| DE (1) | DE60119982T2 (de) |
| DK (1) | DK1355900T3 (de) |
| EA (1) | EA200300716A1 (de) |
| ES (1) | ES2264994T3 (de) |
| HU (1) | HUP0400682A2 (de) |
| IL (1) | IL156518A0 (de) |
| MX (1) | MXPA03005433A (de) |
| NO (1) | NO20032841L (de) |
| PL (1) | PL363238A1 (de) |
| WO (1) | WO2002051832A2 (de) |
| ZA (1) | ZA200305625B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4187642B2 (ja) * | 2001-06-07 | 2008-11-26 | エフ．ホフマン−ラ ロシュ アーゲー | ５−ｈｔ６受容体親和性を有する新規インドール誘導体 |
| US20030225121A1 (en) * | 2001-12-20 | 2003-12-04 | Wyeth | Heterocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands |
| AU2003208711A1 (en) * | 2002-02-12 | 2003-09-04 | Akzo Nobel N.V. | 1-arylsulfonyl-3-substituted indole and indoline derivatives useful in the treatment of central nervous system disorders |
| TW200401641A (en) * | 2002-07-18 | 2004-02-01 | Wyeth Corp | 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands |
| DK1581492T3 (da) * | 2002-11-28 | 2008-11-10 | Suven Life Sciences Ltd | N-arylsulfonyl-3-substituerede indoler med serotoninreceptoraffinitet, fremgangsmåde til fremstilling heraf og en farmaceutisk sammensætning indeholdende disse |
| US20060235222A1 (en) * | 2003-01-22 | 2006-10-19 | Eli Lilly And Company | Indole-derivative modulators of steroid hormone nuclear receptors |
| CN100482662C (zh) * | 2003-02-14 | 2009-04-29 | 惠氏公司 | 作为5-羟基色胺-6配体的杂环基-3-磺酰基氮杂吲哚或-氮杂吲唑衍生物 |
| RU2347780C2 (ru) * | 2003-02-14 | 2009-02-27 | Уайт | Гетероциклил-3-сульфонилиндазолы в качестве лигандов 5-гидрокситриптамина-6 |
| ES2222828B1 (es) | 2003-07-30 | 2006-04-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos. |
| MXPA06000957A (es) * | 2003-07-31 | 2006-03-30 | Wyeth Corp | Compuestos de n-sulfonil heterociclopirrolilalquilamina como ligandos de 5-hidroxitriptamina-6. |
| AU2005335620B2 (en) * | 2005-08-12 | 2009-12-10 | Suven Life Sciences Limited | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands. |
| AU2006280091A1 (en) * | 2005-08-15 | 2007-02-22 | Wyeth | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands |
| WO2007031838A1 (en) | 2005-09-16 | 2007-03-22 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
| EP1842541A1 (de) * | 2006-03-29 | 2007-10-10 | G.I.M.-Gesellschaft Für Innovative Medizin Gmbh Nfg Ohg | Pflanzenextrakte, pflanzliche Wirkstoffe und ihre Verwendung |
| EP2001865A1 (de) * | 2006-04-05 | 2008-12-17 | Wyeth a Corporation of the State of Delaware | Sulfonyl-3-heterocyclylindazol-derivate als 5-hydroxytrytamin-6 liganden |
| WO2007120596A1 (en) * | 2006-04-12 | 2007-10-25 | Wyeth | DIHYDRO[1,4]DIOXINO[2,3-e]INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS |
| PT2124944E (pt) | 2007-03-14 | 2012-05-17 | Ranbaxy Lab Ltd | Derivados de pirazolo[3,4-b]piridina como inibidores de fosfodiesterase |
| JP2010528037A (ja) * | 2007-05-24 | 2010-08-19 | メモリー・ファーマシューティカルズ・コーポレイション | ５−ｈｔ６受容体親和性を有する４’置換化合物 |
| US20100016297A1 (en) * | 2008-06-24 | 2010-01-21 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
| US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
| US20100029629A1 (en) * | 2008-07-25 | 2010-02-04 | Memory Pharmaceuticals Corporation | Acyclic compounds having 5-ht6 receptor affinity |
| US20100056531A1 (en) * | 2008-08-22 | 2010-03-04 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
| US9663498B2 (en) | 2013-12-20 | 2017-05-30 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| CA2953004C (en) | 2014-07-08 | 2023-02-21 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208417A (en) | 1978-06-29 | 1980-06-17 | Pharmindustrie | Indole derivatives and their use as anxiolytics |
| FR2701026B1 (fr) * | 1993-02-02 | 1995-03-31 | Adir | Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| IT1271352B (it) * | 1993-04-08 | 1997-05-27 | Boehringer Ingelheim Italia | Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale |
| US6100291A (en) * | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
| US6133287A (en) * | 1998-03-24 | 2000-10-17 | Allelix Biopharmaceuticals Inc. | Piperidine-indole compounds having 5-HT6 affinity |
| WO1999055697A1 (en) * | 1998-04-29 | 1999-11-04 | American Home Products Corporation | Serotonergic agents |
| US6251893B1 (en) | 1998-06-15 | 2001-06-26 | Nps Allelix Corp. | Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity |
| US6066637A (en) | 1998-06-19 | 2000-05-23 | American Home Products Corporation | Indolyl derivatives as serotonergic agents |
| US6191141B1 (en) | 1999-08-12 | 2001-02-20 | Nps Allelix Corp. | Azaindoles having serotonin receptor affinity |
| BR0114552A (pt) * | 2000-10-20 | 2003-07-01 | Biovitrum Ab | N1- (benzenosulfonil) indóis 2-,3-,4-, 5- substituìdos e seu uso em terapia |
-
2001
- 2001-12-11 IL IL15651801A patent/IL156518A0/xx unknown
- 2001-12-11 HU HU0400682A patent/HUP0400682A2/hu unknown
- 2001-12-11 MX MXPA03005433A patent/MXPA03005433A/es active IP Right Grant
- 2001-12-11 PL PL01363238A patent/PL363238A1/xx unknown
- 2001-12-11 CN CNA018228232A patent/CN1492863A/zh active Pending
- 2001-12-11 DK DK01993251T patent/DK1355900T3/da active
- 2001-12-11 ES ES01993251T patent/ES2264994T3/es not_active Expired - Lifetime
- 2001-12-11 DE DE60119982T patent/DE60119982T2/de not_active Expired - Fee Related
- 2001-12-11 EP EP01993251A patent/EP1355900B1/de not_active Expired - Lifetime
- 2001-12-11 BR BR0116481-3A patent/BR0116481A/pt not_active IP Right Cessation
- 2001-12-11 KR KR10-2003-7008333A patent/KR20030062440A/ko not_active Withdrawn
- 2001-12-11 CA CA002432661A patent/CA2432661A1/en not_active Abandoned
- 2001-12-11 JP JP2002552927A patent/JP2004520325A/ja active Pending
- 2001-12-11 EA EA200300716A patent/EA200300716A1/ru unknown
- 2001-12-11 AT AT01993251T patent/ATE327232T1/de not_active IP Right Cessation
- 2001-12-11 WO PCT/US2001/047938 patent/WO2002051832A2/en active IP Right Grant
- 2001-12-20 US US10/028,487 patent/US6613781B2/en not_active Expired - Fee Related
- 2001-12-21 AR ARP010106003A patent/AR034284A1/es unknown
-
2003
- 2003-06-20 NO NO20032841A patent/NO20032841L/no not_active Application Discontinuation
- 2003-07-21 ZA ZA200305625A patent/ZA200305625B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60119982D1 (de) | 2006-06-29 |
| WO2002051832A2 (en) | 2002-07-04 |
| JP2004520325A (ja) | 2004-07-08 |
| US6613781B2 (en) | 2003-09-02 |
| EP1355900A2 (de) | 2003-10-29 |
| US20020128477A1 (en) | 2002-09-12 |
| PL363238A1 (en) | 2004-11-15 |
| IL156518A0 (en) | 2004-01-04 |
| DK1355900T3 (da) | 2006-09-11 |
| DE60119982T2 (de) | 2006-12-21 |
| ZA200305625B (en) | 2004-10-21 |
| NO20032841D0 (no) | 2003-06-20 |
| HUP0400682A2 (hu) | 2004-06-28 |
| CA2432661A1 (en) | 2002-07-04 |
| EP1355900B1 (de) | 2006-05-24 |
| BR0116481A (pt) | 2004-01-06 |
| AR034284A1 (es) | 2004-02-18 |
| EA200300716A1 (ru) | 2003-12-25 |
| CN1492863A (zh) | 2004-04-28 |
| MXPA03005433A (es) | 2003-09-10 |
| WO2002051832A3 (en) | 2002-09-06 |
| ES2264994T3 (es) | 2007-02-01 |
| KR20030062440A (ko) | 2003-07-25 |
| NO20032841L (no) | 2003-08-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE368658T1 (de) | Hetorocyclindazole und -azaindazole verbindungen als 5-hydroxytryptamine-6 liganden | |
| ATE327232T1 (de) | Heterozyklylalkylindole oder -azaindole als 5- hydroxytryptamine-6 liganden | |
| ATE396191T1 (de) | Azaindolylalkylaminderivate als 5- hydroxytryptamin-6-liganden | |
| DE60134094D1 (de) | C7-taxanester als antitumormittel | |
| ATE312078T1 (de) | 1-aryl-oder 1-alkylsulfonylbenzazol derivate als 5-hydroxytryptamin-6 liganden | |
| IL155443A0 (en) | 1- aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands | |
| ATE335477T1 (de) | Indolylalkylamin-derivate als 5-hydroxytryptamin- 6 liganden | |
| PT1259508E (pt) | Novos biarilcarboxamidas | |
| DE60119407D1 (de) | Filter | |
| ATE391531T1 (de) | Schweisshemmende mittel | |
| DE60130409D1 (de) | Filter | |
| ATA12202000A (de) | Filter | |
| DE50101315D1 (de) | Förderpumpe | |
| NO20030276D0 (no) | Fremgangsmåte | |
| DE60137061D1 (de) | Platin-verbindungen als antitumorwirkstoffe | |
| DE50103731D1 (de) | Förderpumpe | |
| DE50011908D1 (de) | 16-hydroxyestratriene als selektiv wirksame estrogene | |
| DE50112030D1 (de) | Förderpumpe | |
| DE50108721D1 (de) | Pumpenaggregat | |
| DE50209313D1 (de) | Selektive arylguanidinpeptide als urokinaseinhibitoren | |
| DE50111939D1 (de) | Förderpumpe | |
| DE10085473T1 (de) | Erodiermaschine | |
| ATA5832000A (de) | Strumpfhose | |
| ATE287708T1 (de) | 1-amino-alkylcyclohexanederivate als trypanocide mittel | |
| ITMI20011758A0 (it) | Ligandi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |