ATE316097T1 - Peptide mit antibakterieller wirkung - Google Patents

Peptide mit antibakterieller wirkung

Info

Publication number: ATE316097T1
Authority: AT; Austria
Prior art keywords: inhibiting; peptides; antibacterial effects; endotoxemia; tnf
Prior art date: 2000-01-20

Application number

AT01903165T

Other languages

English (en)

Inventor

Kevin H Mayo

Original Assignee

Univ Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-20

Filing date

2001-01-19

Publication date

2006-02-15

2001-01-19 Application filed by Univ Minnesota filed Critical Univ Minnesota

2006-02-15 Application granted granted Critical

2006-02-15 Publication of ATE316097T1 publication Critical patent/ATE316097T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
230000000844 anti-bacterial effect Effects 0.000 title 1
230000002401 inhibitory effect Effects 0.000 abstract 3
MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 1
208000035143 Bacterial infection Diseases 0.000 abstract 1
102000016289 Cell Adhesion Molecules Human genes 0.000 abstract 1
108010067225 Cell Adhesion Molecules Proteins 0.000 abstract 1
208000037487 Endotoxemia Diseases 0.000 abstract 1
108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
230000033115 angiogenesis Effects 0.000 abstract 1
239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
208000022362 bacterial infectious disease Diseases 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
230000003828 downregulation Effects 0.000 abstract 1
210000002889 endothelial cell Anatomy 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT01903165T 2000-01-20 2001-01-19 Peptide mit antibakterieller wirkung ATE316097T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17725500P	2000-01-20	2000-01-20
US21029700P	2000-06-08	2000-06-08

Publications (1)

Publication Number	Publication Date
ATE316097T1 true ATE316097T1 (de)	2006-02-15

Family

ID=26873090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01903165T ATE316097T1 (de)	2000-01-20	2001-01-19	Peptide mit antibakterieller wirkung

Country Status (8)

Country	Link
US (1)	US7144982B2 (de)
EP (1)	EP1252181B1 (de)
AT (1)	ATE316097T1 (de)
AU (1)	AU2001231016A1 (de)
CA (1)	CA2397835A1 (de)
DE (1)	DE60116733T2 (de)
ES (1)	ES2252187T3 (de)
WO (1)	WO2001053335A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997044354A2 (en) *	1996-05-24	1997-11-27	Regents Of The University Of Minnesota	Synthesis of soluble beta-sheet forming peptides
CA2397835A1 (en)	2000-01-20	2001-07-26	Regents Of The University Of Minnesota	Polypeptides with therapeutic activity and methods of use
JP2005536453A (ja)	2002-02-20	2005-12-02	リージェンツオブザユニバーシティオブミネソタ	部分的なペプチド擬似物及び方法
EP1380290A1 (de)	2002-07-09	2004-01-14	Universitair Medisch Centrum Utrecht	Cross-Beta-Strukturweg und seine therapeutische Relevanz
CA2505918C (en) *	2002-11-15	2011-02-01	Nipro Corporation	A liposome having bound albumin and peg
BRPI0406470A (pt) *	2003-01-09	2005-12-06	Genentech Inc	Método para a purificação de polipeptìdeo heterólogo e caldo ou homogeneizado de fermentação
WO2005009457A1 (en) *	2003-05-15	2005-02-03	Sangstat Medical Corporation	Rdp58 compositions and methods for inhibiting vascularization of cell populations
CA2541856A1 (en) *	2003-10-17	2005-05-12	Regents Of The University Of Minnesota	Modified polypeptides with therapeutic activity and methods of use
WO2005090389A2 (en) *	2004-03-17	2005-09-29	Aplagen Gmbh	Isosteric transformation
ES2378999T3 (es) *	2004-10-04	2012-04-19	Regents Of The University Of Minnesota	Miméticos con conformación peptídica a base de calixareno, métodos de uso, y métodos para obtenerlos
ATE554394T1 (de)	2005-07-13	2012-05-15	Crossbeta Biosciences Bv	Cross-beta-struktur-bindende verbindungen
US8114832B2 (en)	2005-07-13	2012-02-14	Crossbeta Biosciences B.V.	Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
US10611799B2 (en) *	2017-03-03	2020-04-07	National Tsing Hua University	Anti-endotoxin polypeptide
US10973908B1 (en)	2020-05-14	2021-04-13	David Gordon Bermudes	Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4938949A (en) *	1988-09-12	1990-07-03	University Of New York	Treatment of damaged bone marrow and dosage units therefor
US5595887A (en) *	1990-07-16	1997-01-21	Bionebraska, Inc.	Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
US5348942A (en) *	1993-03-12	1994-09-20	Xoma Corporation	Therapeutic uses of bactericidal/permeability increasing protein products
US5447913A (en) *	1994-03-11	1995-09-05	Xoma Corporation	Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5830860A (en) *	1994-03-24	1998-11-03	Regents Of The University Of Minnesota	Peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
US5786324A (en) *	1994-03-24	1998-07-28	Regents Of The University Of Minnesota	Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
US5955577A (en) *	1996-06-27	1999-09-21	Regents Of The University Of Minnesota	Method for synthesizing a water-soluble β-sheet forming peptide
AU1067699A (en)	1997-10-07	1999-04-27	New England Medical Center Hospitals, Inc., The	Structure-based rational design of compounds to inhibit papillomavirus infe ction
JP4037525B2 (ja)	1998-03-25	2008-01-23	生化学工業株式会社	新規抗菌性ペプチド
CA2397835A1 (en)	2000-01-20	2001-07-26	Regents Of The University Of Minnesota	Polypeptides with therapeutic activity and methods of use

2001
- 2001-01-19 CA CA002397835A patent/CA2397835A1/en not_active Abandoned
- 2001-01-19 AU AU2001231016A patent/AU2001231016A1/en not_active Abandoned
- 2001-01-19 AT AT01903165T patent/ATE316097T1/de not_active IP Right Cessation
- 2001-01-19 ES ES01903165T patent/ES2252187T3/es not_active Expired - Lifetime
- 2001-01-19 EP EP01903165A patent/EP1252181B1/de not_active Expired - Lifetime
- 2001-01-19 DE DE60116733T patent/DE60116733T2/de not_active Expired - Lifetime
- 2001-01-19 WO PCT/US2001/001916 patent/WO2001053335A2/en active IP Right Grant
- 2001-01-19 US US09/766,353 patent/US7144982B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE60116733D1 (de)	2006-04-06
WO2001053335A3 (en)	2001-12-13
AU2001231016A1 (en)	2001-07-31
DE60116733T2 (de)	2006-11-02
EP1252181A2 (de)	2002-10-30
WO2001053335A9 (en)	2002-10-31
WO2001053335A2 (en)	2001-07-26
ES2252187T3 (es)	2006-05-16
CA2397835A1 (en)	2001-07-26
US20020146406A1 (en)	2002-10-10
EP1252181B1 (de)	2006-01-18
US7144982B2 (en)	2006-12-05

Publication	Publication Date	Title
ATE316097T1 (de)	2006-02-15	Peptide mit antibakterieller wirkung
ES2160335T3 (es)	2001-11-01	Polimeros reticulables.
DE50008510D1 (de)	2004-12-09	Niedermolekulare inhibitoren von komplementproteasen
PT814827E (pt)	2003-11-28	Factor de crescimento vascular endotelial-b
DK1261360T3 (da)	2010-05-03	Casein-afledte peptider og anvendelser deraf i behandling
ATE421973T1 (de)	2009-02-15	Inzektizide proteinen von bacillus thuringiensis
DE602005013648D1 (de)	2009-05-14	Behandlung von bakteriellen infektionen
WO2002028902A3 (en)	2002-12-05	Nectin polypeptides, polynucleotides, methods of making and use thereof
WO2002079408A3 (en)	2002-11-28	Short bioactive peptides and methods for their use
DE69533704D1 (de)	2004-12-02	Bradykinin-antagonist peptide mit n-substituierten glycinen
ATE313562T1 (de)	2006-01-15	Antimicrobielle wirkung des ersten kationischen cluster des menschlichen lactoferrins
AU2002351933A1 (en)	2003-05-19	Men protein, gst2, rab-rp1, csp, f-box protein lilina/fbl7, abc50, coronin, sec61 alpha, or vhappa1-1, or homologous proteins involved in the regulation of energy homeostasis
DK1169340T3 (da)	2007-09-24	Lantibiotikum
AU7980300A (en)	2001-04-23	Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics
NO20040880L (no)	2004-04-20	Casein avledete peptider og anvendelser derav i terapi.
ATE474589T1 (de)	2010-08-15	Angiogene peptide und ihre verwendungen
AU2001244286A1 (en)	2001-10-03	Peptide sequences comprising one or several protein binding units of the ena/vasp family, and uses thereof
AU2003239184A8 (en)	2003-11-17	Treatment and inhibition of ocular infections and wounds by cap37 and cap37 peptides
WO2002000686A3 (en)	2002-05-02	Bioelastomer nanomachines and biosensors
ATE269101T1 (de)	2004-07-15	Rekombinantes sp-a zur behandlung und vorbeugung von pulmonaren infektionen und entzündungen
WO2001056593A3 (en)	2002-04-25	Use of vascular endothelial growth factor, placenta growth factor or both for preventing or treating ischemic diseases or stroke
EP1315752A4 (de)	2005-07-06	Veränderte proteine, isolierte neuartige peptide und anwendungen derselben
DK1748785T3 (da)	2008-11-24	Peptider til modulering af bruskhomeostase
FR2654430B1 (fr)	1995-01-06	Nouveaux derives de peptides, utilisables comme inhibiteurs des collagenases bacteriennes.
DK1897945T3 (da)	2012-05-07	IL-17 homologe polypeptider og terapeutiske anvendelser deraf.

Legal Events

Date	Code	Title	Description
2006-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties