ATE310098T1 - Dna kodierend für glutaminsäure-gesteuerte chloridkanäle - Google Patents

Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Info

Publication number: ATE310098T1
Authority: AT; Austria
Prior art keywords: host cells; chloride channels; glutamic acid; dna coding; recombinant host
Prior art date: 1995-05-05

Application number

AT96913285T

Other languages

English (en)

Inventor

Doris F Cully

Joseph P Arena

Philip S Paress

Ken K Liu

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-05

Filing date

1996-05-01

Publication date

2005-12-15

1996-05-01 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE310098T1 publication Critical patent/ATE310098T1/de

Links

108010062745 Chloride Channels Proteins 0.000 title 1
102000011045 Chloride Channels Human genes 0.000 title 1
102000005962 receptors Human genes 0.000 abstract 3
108020003175 receptors Proteins 0.000 abstract 3
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
229930195712 glutamate Natural products 0.000 abstract 2
239000005660 Abamectin Substances 0.000 abstract 1
108091006146 Channels Proteins 0.000 abstract 1
108050006905 Glutamate-Gated Chloride Channel Proteins 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
230000002141 anti-parasite Effects 0.000 abstract 1
239000003096 antiparasitic agent Substances 0.000 abstract 1
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
239000013057 ectoparasiticide Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000002917 insecticide Substances 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT96913285T 1995-05-05 1996-05-01 Dna kodierend für glutaminsäure-gesteuerte chloridkanäle ATE310098T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/435,933 US5693492A (en)	1995-05-05	1995-05-05	DNA encoding glutamate gated chloride channels
PCT/US1996/006035 WO1996034940A1 (en)	1995-05-05	1996-05-01	Dna encoding glutamate gated chloride channels

Publications (1)

Publication Number	Publication Date
ATE310098T1 true ATE310098T1 (de)	2005-12-15

Family

ID=23730421

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96913285T ATE310098T1 (de)	1995-05-05	1996-05-01	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Country Status (8)

Country	Link
US (1)	US5693492A (de)
EP (1)	EP0871703B1 (de)
JP (1)	JP3862278B2 (de)
AT (1)	ATE310098T1 (de)
CA (1)	CA2220116C (de)
DE (1)	DE69635455T2 (de)
ES (1)	ES2250989T3 (de)
WO (1)	WO1996034940A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels
US6358701B1 (en) *	1997-08-11	2002-03-19	Merck & Co., Inc.	DNA molecules encoding Ctenocephalides felis glutamate gated chloride channels
DE19819829A1 (de) *	1998-05-04	1999-11-11	Bayer Ag	Nukleinsäuren, die für Acetylcholinrezeptor-Untereinheiten von Insekten kodieren
WO2001030849A1 (en) *	1999-10-22	2001-05-03	Merck & Co., Inc.	Dna molecules encoding l-glutamate-gated chloride channels from schistocerca americana
US7244586B2 (en) *	2000-03-02	2007-07-17	Merck & Co., Inc.	DNA molecules encoding ligand-gated ion channels from Drosophila melanogaster
DE10013619A1 (de) *	2000-03-18	2001-10-11	Bayer Ag	Ligandengesteuerte Anionenkanäle von Insekten
US7202054B2 (en) *	2000-03-31	2007-04-10	Merial Limited	DNA molecules encoding L-glutamate-gated chloride channels from Rhipicephalus sanguineus
DK1280821T3 (da)	2000-03-31	2007-02-05	Merial Ltd	DNA-molekyler der koder for ligand-gatede ionkanaler fra dermacentor variabilis
US7220832B2 (en) *	2000-03-31	2007-05-22	Merck & Co., Inc	Dermacentor variabilis GABA-gated chloride channels
US7267964B2 (en)	2000-03-31	2007-09-11	Merial Limited	DNA molecules encoding ligand gated ion channels from Dermacentor variabilis
US6329174B1 (en) *	2000-06-13	2001-12-11	Aventis Cropscience Sa	Nucleic acid encoding lepidoteran glutamate-gated chloride channel
WO2006040153A2 (en) *	2004-10-13	2006-04-20	Ablynx N.V.	Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
CN103254309B (zh)	2005-05-18	2017-09-26	埃博灵克斯股份有限公司	针对肿瘤坏死因子α的改进的纳米体TM
LT2444424T (lt)	2005-05-20	2018-10-25	Ablynx N.V.	Pagerintos tm nanodalelės, skirtos agregacijos sąlygotų sutrikimų gydymui
CA2673331A1 (en)	2006-12-19	2008-06-26	Ablynx N.V.	Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
EP2514767A1 (de)	2006-12-19	2012-10-24	Ablynx N.V.	Gegen Metalloproteinase der ADAM-Familie gerichtete Aminosäuren und Polypeptide damit zur Behandlung von Erkrankungen und Störungen im Zusammenhang mit ADAM
EP2947097A1 (de)	2008-04-07	2015-11-25	Ablynx N.V.	Gegen Notch-Signalwege gerichtete Aminosäuresequenzen und Verwendungen davon
AU2009329501B2 (en)	2008-12-19	2015-11-26	Ablynx N.V.	Genetic immunization for producing immunoglobulins against cell-associated antigens such as P2X7, CXCR7 or CXCR4
CN105399828B (zh)	2009-04-10	2021-01-15	埃博灵克斯股份有限公司	用于治疗il-6r相关疾病和病症的改进的针对il-6r的氨基酸序列和包含其的多肽
LT2438087T (lt)	2009-06-05	2017-08-25	Ablynx N.V.	Trivalenčiai nanokūno konstruktai prieš žmogaus respiratorinį sincitinį virusą (hrsv), skirti kvėpavimo takų infekcijų profilaktikai ir (arba) gydymui
EP2507262A1 (de)	2009-11-30	2012-10-10	Ablynx N.V.	Verbesserte gegen hrsv gerichtete aminosäuresequenzen und polypeptide damit zur prävention und/oder behandlung von atemwegsinfektionen
WO2011083140A1 (en)	2010-01-08	2011-07-14	Ablynx Nv	Immunoglobulin single variable domain directed against human cxcr4
NL2013661B1 (en)	2014-10-21	2016-10-05	Ablynx Nv	KV1.3 Binding immunoglobulins.
CN110177809B (zh)	2016-11-16	2023-11-03	埃博灵克斯股份有限公司	能够结合CD123和TCRα/β的T细胞募集多肽
US20200392512A1 (en)	2018-02-26	2020-12-17	Ablynx N.V.	Nucleotide sequences encoding peptide linkers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5385831A (en) *	1990-12-12	1995-01-31	Zymogenetics, Inc.	Method for producing a mammalian G protein coupled glutamate receptor
NZ240921A (en) *	1990-12-12	1994-06-27	Zymogenetics Inc	G protein coupled glutamate receptor (neurotransmitters), recombinant production
AU2343092A (en) *	1991-04-02	1992-12-21	Baylor College Of Medicine	A high-affinity human glutamate/aspartate uptake system
GB9112504D0 (en) *	1991-06-11	1991-07-31	Merck Sharp & Dohme	Cell line
WO1993007161A1 (en) *	1991-10-04	1993-04-15	Cornell Research Foundation, Inc.	Molecular cloning and transformation of cyclodiene resistance
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels

1995
- 1995-05-05 US US08/435,933 patent/US5693492A/en not_active Expired - Lifetime
1996
- 1996-05-01 EP EP96913285A patent/EP0871703B1/de not_active Expired - Lifetime
- 1996-05-01 AT AT96913285T patent/ATE310098T1/de not_active IP Right Cessation
- 1996-05-01 ES ES96913285T patent/ES2250989T3/es not_active Expired - Lifetime
- 1996-05-01 JP JP53343596A patent/JP3862278B2/ja not_active Expired - Lifetime
- 1996-05-01 WO PCT/US1996/006035 patent/WO1996034940A1/en active IP Right Grant
- 1996-05-01 CA CA2220116A patent/CA2220116C/en not_active Expired - Lifetime
- 1996-05-01 DE DE69635455T patent/DE69635455T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2250989T3 (es)	2006-04-16
CA2220116A1 (en)	1996-11-07
DE69635455D1 (de)	2005-12-22
WO1996034940A1 (en)	1996-11-07
JPH11506906A (ja)	1999-06-22
DE69635455T2 (de)	2006-08-03
EP0871703A1 (de)	1998-10-21
US5693492A (en)	1997-12-02
CA2220116C (en)	2011-04-19
EP0871703B1 (de)	2005-11-16
JP3862278B2 (ja)	2006-12-27
EP0871703A4 (de)	2000-03-01

Publication	Publication Date	Title
ATE310098T1 (de)	2005-12-15	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle
HUP0101136A2 (hu)	2001-08-28	Fehérjeexpresszió baculovírus-vektort alkalmazó expressziós rendszerben
ATE282087T1 (de)	2004-11-15	Modifiziertes enzym mit lipolytischer aktivität
ATE443437T1 (de)	2009-10-15	Modifiziertes bacillus thuringiensis gen zur kontrolle von lepidoptera in pflanzen
ATE389666T1 (de)	2008-04-15	Hohe expressionsrate von proteinen
BR9508981A (pt)	1997-12-30	Mutantes de subtilisina isentos de cálcio
DE69635452D1 (de)	2005-12-22	Hohe expressionsrate des grün-fluoreszierenden proteins
IL118201A0 (en)	1996-09-12	Erythropoietin free of animal proteins processes for production and use thereof
ATE449175T1 (de)	2009-12-15	Bakterielle produktion von interferon-beta polypeptiden
ATE283368T1 (de)	2004-12-15	Für die glutamatabhängigen chloridkanäle kodierende dna
EP0967283A4 (de)	2004-06-09	Gene, die für proteine mit transglykolysierungsaktivität kodieren.
DE69736389T8 (de)	2007-11-22	Proteine mit zellulase-aktivitäten und prozess für ihre herstellung
WO2000063415A8 (en)	2001-01-18	Dna encoding the human vanilloid receptor vr1
CA2032167A1 (en)	1990-11-02	Dna coding for protein binds to enhancer of.alpha.-fetoprotein gene
DE60132571D1 (de)	2008-03-13	Für den menschlichen vanilloid-rezeptor vr3 kodierende dns
ATE345382T1 (de)	2006-12-15	2,6-beta-d-fruktanhydrolase enzym und verfahren zu dessen verwendung
DE60129688D1 (de)	2007-09-13	Die menschliche beta-1a-untereinheit des potential-abhängigen natriumkanals und deren verwendungen
DE60033297D1 (de)	2007-03-22	Für die humane untereinheit 5-ht3-c des serotoninrezeptors 5-ht3 kodierende dna
MY104405A (en)	1994-03-31	Structural gene comprising dna coding for an endotoxin protein having toxic activity against insects.
ATE202798T1 (de)	2001-07-15	D-aminosäure-oxidase kodierendes dns-fragment
ATE266094T1 (de)	2004-05-15	Produktion des proteins ingap mit hoher expressionsrate
DE59611293D1 (de)	2005-12-15	Protein mit dnase-aktivität
AU654155B2 (en)	1994-10-27	A DNA encoding a protein which binds to the enhancer of alpha-fetoprotein gene
KR950704352A (ko)	1995-11-20	테라포시데 아포노펠마로부터의 칼슘 통로 차단 폴리펩티드(calcium channel blocking polypeptides from theraphosidae aphonopelma)

Legal Events

Date	Code	Title	Description
2006-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties