ATE30919T1 - Magensekretion hemmende peptidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. - Google Patents
Magensekretion hemmende peptidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.Info
- Publication number
- ATE30919T1 ATE30919T1 AT84400787T AT84400787T ATE30919T1 AT E30919 T1 ATE30919 T1 AT E30919T1 AT 84400787 T AT84400787 T AT 84400787T AT 84400787 T AT84400787 T AT 84400787T AT E30919 T1 ATE30919 T1 AT E30919T1
- Authority
- AT
- Austria
- Prior art keywords
- tyr
- asp
- glu
- thr
- ala
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 3
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 2
- CIQHWLTYGMYQQR-QMMMGPOBSA-N O(4')-sulfo-L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OS(O)(=O)=O)C=C1 CIQHWLTYGMYQQR-QMMMGPOBSA-N 0.000 abstract 2
- 229930182817 methionine Natural products 0.000 abstract 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 2
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
- LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004744 butyloxycarbonyl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000001012 protector Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8306492A FR2544715B1 (fr) | 1983-04-20 | 1983-04-20 | Nouveaux derives peptidiques inhibiteurs de la secretion gastrique et procede pour leur preparation |
| EP84400787A EP0124420B1 (de) | 1983-04-20 | 1984-04-19 | Magensekretion hemmende Peptidderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE30919T1 true ATE30919T1 (de) | 1987-12-15 |
Family
ID=9288053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84400787T ATE30919T1 (de) | 1983-04-20 | 1984-04-19 | Magensekretion hemmende peptidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4636490A (de) |
| EP (1) | EP0124420B1 (de) |
| JP (1) | JPS6034995A (de) |
| AT (1) | ATE30919T1 (de) |
| CA (1) | CA1249100A (de) |
| DE (1) | DE3467581D1 (de) |
| FR (1) | FR2544715B1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2544715B1 (fr) * | 1983-04-20 | 1985-12-13 | Sanofi Sa | Nouveaux derives peptidiques inhibiteurs de la secretion gastrique et procede pour leur preparation |
| IL84478A0 (en) * | 1986-11-18 | 1988-04-29 | Pennwalt Corp | Peptides with sulfate ester groups and their preparation |
| US4888385A (en) * | 1987-04-30 | 1989-12-19 | Millipore Corporation | BOP reagent for solid phase peptide synthesis |
| US4943561A (en) * | 1988-11-28 | 1990-07-24 | Merck & Co., Inc. | Gastrin releasing peptide antagonist |
| US5189016A (en) * | 1990-05-18 | 1993-02-23 | Clintec Nutrition Co. | Nutrient compositions containing peptides and method for administering the same |
| US5122515A (en) * | 1990-06-19 | 1992-06-16 | Smith Ross C | Nutrient composition containing dipeptides and method for administering the same |
| RU2449805C1 (ru) * | 2011-01-27 | 2012-05-10 | Общество С Ограниченной Ответственностью "Гармония" | Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования |
| CN104276966A (zh) * | 2014-11-04 | 2015-01-14 | 崇州合瑞科技有限公司 | 一种制备Boc-L-天冬氨酸的方法 |
| CN113461574B (zh) * | 2021-07-05 | 2023-04-11 | 成都郑源生化科技有限公司 | Fmoc-AA-NH2的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1042487A (en) * | 1964-06-25 | 1966-09-14 | Ici Ltd | Polypeptide derivatives |
| US4351829A (en) * | 1980-09-26 | 1982-09-28 | Farmitalia Carlo Erba Spa | Use of polypeptides as analgesic drugs |
| FR2544715B1 (fr) * | 1983-04-20 | 1985-12-13 | Sanofi Sa | Nouveaux derives peptidiques inhibiteurs de la secretion gastrique et procede pour leur preparation |
-
1983
- 1983-04-20 FR FR8306492A patent/FR2544715B1/fr not_active Expired
-
1984
- 1984-04-06 US US06/597,427 patent/US4636490A/en not_active Expired - Fee Related
- 1984-04-09 CA CA000451551A patent/CA1249100A/fr not_active Expired
- 1984-04-19 JP JP59077629A patent/JPS6034995A/ja active Pending
- 1984-04-19 DE DE8484400787T patent/DE3467581D1/de not_active Expired
- 1984-04-19 AT AT84400787T patent/ATE30919T1/de not_active IP Right Cessation
- 1984-04-19 EP EP84400787A patent/EP0124420B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1249100A (fr) | 1989-01-17 |
| EP0124420A3 (en) | 1985-11-27 |
| FR2544715B1 (fr) | 1985-12-13 |
| US4636490A (en) | 1987-01-13 |
| JPS6034995A (ja) | 1985-02-22 |
| FR2544715A1 (fr) | 1984-10-26 |
| DE3467581D1 (en) | 1987-12-23 |
| EP0124420B1 (de) | 1987-11-19 |
| EP0124420A2 (de) | 1984-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |