[go: up one dir, main page]

ATE307196T1 - Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung - Google Patents

Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung

Info

Publication number
ATE307196T1
ATE307196T1 AT98939101T AT98939101T ATE307196T1 AT E307196 T1 ATE307196 T1 AT E307196T1 AT 98939101 T AT98939101 T AT 98939101T AT 98939101 T AT98939101 T AT 98939101T AT E307196 T1 ATE307196 T1 AT E307196T1
Authority
AT
Austria
Prior art keywords
bird
long
cell line
germ cell
primordial germ
Prior art date
Application number
AT98939101T
Other languages
English (en)
Inventor
De Leon F Abel Ponce
Catherine Blackwell
Xiu Ying Gao
James M Robl
Steven L Stice
D Joseph Jerry
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/905,773 external-priority patent/US6156569A/en
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Application granted granted Critical
Publication of ATE307196T1 publication Critical patent/ATE307196T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/30—Bird
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Catching Or Destruction (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98939101T 1997-08-04 1998-08-04 Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung ATE307196T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/905,773 US6156569A (en) 1997-08-04 1997-08-04 Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians
US12762498A 1998-08-03 1998-08-03
PCT/US1998/015635 WO1999006533A1 (en) 1997-08-04 1998-08-04 Avian primordial germ cell (pgc) cell line and a method for long term culturing thereof

Publications (1)

Publication Number Publication Date
ATE307196T1 true ATE307196T1 (de) 2005-11-15

Family

ID=26825804

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98939101T ATE307196T1 (de) 1997-08-04 1998-08-04 Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung

Country Status (12)

Country Link
US (1) US20040226058A1 (de)
EP (2) EP1007633B1 (de)
JP (1) JP2003532364A (de)
CN (1) CN1195844C (de)
AT (1) ATE307196T1 (de)
AU (1) AU736087B2 (de)
BR (1) BR9811830A (de)
CA (1) CA2300380A1 (de)
DE (1) DE69831958T2 (de)
ES (1) ES2252851T3 (de)
NZ (1) NZ502712A (de)
WO (1) WO1999006533A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100378747B1 (ko) * 1999-02-11 2003-04-07 한미약품공업 주식회사 조류의 다능성 배자생식세포주 및 이의 제조방법
US6333192B1 (en) 1999-08-09 2001-12-25 North Carolina State University Method of producing an undifferentiated avian cell culture using avian primordial germ cells
US6354242B1 (en) 2000-03-23 2002-03-12 North Carolina State University Methods for gamete production in birds
CN1568366B (zh) 2001-08-13 2013-04-24 恩布里克斯公司 注射鸟卵的方法
FR2836924B1 (fr) * 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
KR100569168B1 (ko) * 2003-08-08 2006-04-07 (주)아비코아생명공학연구소 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포
US20060174362A1 (en) 2005-02-01 2006-08-03 Origen Therapeutics, Inc. Long-term culture of avian primordial germ cells (PGCs)
CN100366734C (zh) * 2006-03-02 2008-02-06 扬州大学 一种鸡精原细胞分离纯化方法
RU2473688C2 (ru) 2006-08-09 2013-01-27 Вивалис Способ получения трансгенных птиц с использованием эмбриональных стволовых клеток
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
EP1985305A1 (de) 2007-04-24 2008-10-29 Vivalis Aus Entenembryonen gewonnene Stammzellkulturen zur Herstellung von Impfstoffen gegen Viren
CA2770825A1 (en) 2009-08-13 2011-02-17 Crystal Bioscience Inc. Transgenic animal for production of antibodies having minimal cdrs
US8865462B2 (en) * 2010-01-20 2014-10-21 Crystal Bioscience Inc. Sustained culture of avian gonocytes
AU2013204327B2 (en) 2012-04-20 2016-09-01 Aviagen Cell transfection method
CN103674653B (zh) * 2013-12-19 2016-08-24 浙江省农业科学院 一种原始生殖细胞的爬片方法
WO2016091272A1 (en) * 2014-12-12 2016-06-16 Central Veterinary Research Laboratory System and method for establishing a long-term culture of avian primordial germ cells and uses thereof
CA3128360A1 (en) 2019-03-05 2020-09-10 Yuval CINNAMON Genome-edited birds
CN111500531A (zh) * 2020-05-15 2020-08-07 扬州大学 一种鸡PGCs在体外长期培养的方法
CN116210647B (zh) * 2023-02-03 2024-12-13 威奥福生物科技(宁波)有限公司 一种使用原始生殖细胞干细胞系扩繁白羽肉鸡的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
US6156569A (en) * 1997-08-04 2000-12-05 University Of Massachusetts Office Of Vice Chancellor For Research At Amherst Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians
US6140118A (en) * 1999-08-11 2000-10-31 Wisconsin Alumni Research Foundation Avian blastodermal cell lines

Also Published As

Publication number Publication date
BR9811830A (pt) 2000-08-15
EP1007633A4 (de) 2002-06-05
NZ502712A (en) 2003-01-31
DE69831958D1 (de) 2006-03-02
CN1273600A (zh) 2000-11-15
CN1195844C (zh) 2005-04-06
ES2252851T3 (es) 2006-05-16
WO1999006533A1 (en) 1999-02-11
EP1007633A1 (de) 2000-06-14
DE69831958T2 (de) 2006-07-27
AU736087B2 (en) 2001-07-26
CA2300380A1 (en) 1999-02-11
AU8759398A (en) 1999-02-22
US20040226058A1 (en) 2004-11-11
JP2003532364A (ja) 2003-11-05
EP1007633B1 (de) 2005-10-19
EP1616943A1 (de) 2006-01-18

Similar Documents

Publication Publication Date Title
ATE307196T1 (de) Primordiale keimzellinie aus vögeln und verfahren zu deren langzeitkultivierung
EP1019491A4 (de) Herstellung embryonischer vogel keimzellinien durch verlängerte kultivierung von pgcs, verwendung desselben zur klonierung und chimerisierung
ATE329040T1 (de) Reversibles kern-genetisches system für männliche sterilität in transgenen pflanzen
DE3867743D1 (de) Benzamid-derivat, verfahren zu dessen herstellung und pflanzenwachstumsregulator.
ATE307211T1 (de) Verfahren zur herstellung transgener pflanzen
FI19991646L (fi) Menetelmä kasvien kasvun lisäämiseksi
ATE284865T1 (de) Benzoylcyclohexandione, verfahren zu ihrer herstellung und ihre verwendung als herbizide und pflanzenwachstumsregulatoren
DE69835209D1 (de) Regulatorische sequenzen für transgene pflanzen
DE69113502D1 (de) Verfahren zur Herstellung von Turbinenschaufeln.
DE3778221D1 (de) Faserverschlingungen und verfahren zur herstellung derselben.
DE3575136D1 (de) Cyclohexenonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses.
DE60038748D1 (de) Mykotoxin-resistente transgene Pflanze und Verfahren zur Herstellung und Verwendung derselben
ATE414417T1 (de) Translations-kontrollelemente für proteinexpression mit hoher ausbeute in den plastiden von höheren pflanzen und verfahren zu deren verwendung
EP0921822A4 (de) Tiermodell für transplantation
DE69209734D1 (de) Dithiocarbaminsäure salze, verfahren zur herstellung und verfahren zur herstellung von isothiocyanaten aus diesen salzen
DE69117846D1 (de) Einstufiges Kulturverfahren für Vogelembryos
DE69525456D1 (de) Verfahren zur kultivierung von vogelzellen
ATE241903T1 (de) Auslöser für den bluteinsatz
DE69835812D1 (de) Anwendungsmoeglichkeiten der maennlichen sterilitaet von pflanzen
DE59508742D1 (de) Verfahren zur herstellung 1,3-disubstituierter imidazolidinone
AT383253B (de) N-phenylpyrazolderivate enthaltende herbizidformulierungen, deren verwendung und verfahren zur bekaempfung des unkrautwachstums
DE69210420D1 (de) Verfahren und vorrichtung zum ernten von pflanzen
NO912518L (no) For som fremmer vekst og tarmfunksjon hos dyr.
DE3761767D1 (de) Verfahren zur herstellung optisch aktiver 2-hydroxyethyl-azol- derivate.
DE3482469D1 (de) N-acyl-anthranilsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1007633

Country of ref document: EP

REN Ceased due to non-payment of the annual fee