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ATE30324T1 - Piperazin-derivate von theobromin. - Google Patents

Piperazin-derivate von theobromin.

Info

Publication number
ATE30324T1
ATE30324T1 AT82401446T AT82401446T ATE30324T1 AT E30324 T1 ATE30324 T1 AT E30324T1 AT 82401446 T AT82401446 T AT 82401446T AT 82401446 T AT82401446 T AT 82401446T AT E30324 T1 ATE30324 T1 AT E30324T1
Authority
AT
Austria
Prior art keywords
chob
integer
zero
image
theobromine
Prior art date
Application number
AT82401446T
Other languages
English (en)
Inventor
Colette Favier
Henri Pinhas
Serge Beranger
Jean-Claude Pascal
Original Assignee
Syntex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Lab filed Critical Syntex Lab
Application granted granted Critical
Publication of ATE30324T1 publication Critical patent/ATE30324T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT82401446T 1981-07-31 1982-07-30 Piperazin-derivate von theobromin. ATE30324T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/288,847 US4374837A (en) 1981-07-31 1981-07-31 Piperazine derivatives of theobromine
EP82401446A EP0071543B1 (de) 1981-07-31 1982-07-30 Piperazin-Derivate von Theobromin

Publications (1)

Publication Number Publication Date
ATE30324T1 true ATE30324T1 (de) 1987-11-15

Family

ID=23108917

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82401446T ATE30324T1 (de) 1981-07-31 1982-07-30 Piperazin-derivate von theobromin.

Country Status (12)

Country Link
US (1) US4374837A (de)
EP (1) EP0071543B1 (de)
JP (1) JPS5826886A (de)
AT (1) ATE30324T1 (de)
AU (1) AU560432B2 (de)
CA (1) CA1223875A (de)
DE (1) DE3277505D1 (de)
DK (1) DK151965C (de)
ES (1) ES514553A0 (de)
IE (1) IE53692B1 (de)
NZ (1) NZ201437A (de)
ZA (1) ZA825528B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087810B1 (de) * 1982-03-02 1986-06-25 Eisai Co., Ltd. Antiphlogistische antipyretische analgesische pharmazeutische Zusammensetzungen mit Theophyllin-Derivaten als wirksame Bestandteile
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4810706A (en) * 1985-12-20 1989-03-07 Recherche Syntex Piperazine derivatives of theophylline and theobromine
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE1620576A1 (de) * 1966-11-25 1970-02-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
DE1966620A1 (de) * 1969-03-20 1973-05-24 Walter Dr Bestian Verfahren zur herstellung von dialkylxanthin-derivaten
GB1289287A (de) * 1969-03-28 1972-09-13
DE2963600D1 (en) * 1978-04-27 1982-10-28 Laroche Navarron Sa Piperazine methane imine derivatives, methods for their preparation and their therapeutical use
JPS55118488A (en) * 1979-03-05 1980-09-11 Eisai Co Ltd Theobromine derivative and its preparation
US4374835A (en) * 1980-01-31 1983-02-22 Laroche-Navarron, S.A. Piperazine derivatives of theophylline

Also Published As

Publication number Publication date
IE821841L (en) 1983-01-31
JPS5826886A (ja) 1983-02-17
ZA825528B (en) 1984-03-28
US4374837A (en) 1983-02-22
CA1223875A (en) 1987-07-07
EP0071543B1 (de) 1987-10-21
NZ201437A (en) 1985-12-13
IE53692B1 (en) 1989-01-18
DE3277505D1 (en) 1987-11-26
DK151965C (da) 1988-06-20
EP0071543A1 (de) 1983-02-09
DK342882A (da) 1983-02-01
AU560432B2 (en) 1987-04-09
DK151965B (da) 1988-01-18
ES8400430A1 (es) 1983-11-01
AU8666382A (en) 1983-02-03
ES514553A0 (es) 1983-11-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee