ATE296355T1 - Universelle integrations- und expressionsvektoren für chloroplasten, transformierte pflanzen und produkte hiervon - Google Patents
Universelle integrations- und expressionsvektoren für chloroplasten, transformierte pflanzen und produkte hiervonInfo
- Publication number
- ATE296355T1 ATE296355T1 AT98935230T AT98935230T ATE296355T1 AT E296355 T1 ATE296355 T1 AT E296355T1 AT 98935230 T AT98935230 T AT 98935230T AT 98935230 T AT98935230 T AT 98935230T AT E296355 T1 ATE296355 T1 AT E296355T1
- Authority
- AT
- Austria
- Prior art keywords
- transformed
- plants
- transformed plants
- resistance
- expression vectors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8214—Plastid transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
- C12N15/8275—Glyphosate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
- C12N15/8278—Sulfonylurea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Insects & Arthropods (AREA)
- Pest Control & Pesticides (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5531497P | 1997-08-07 | 1997-08-07 | |
US7904298P | 1998-03-23 | 1998-03-23 | |
US09/079,640 US7129391B1 (en) | 1988-09-26 | 1998-05-15 | Universal chloroplast integration and expression vectors, transformed plants and products thereof |
PCT/IB1998/001199 WO1999010513A1 (en) | 1997-08-07 | 1998-08-05 | Universal chloroplast integration and expression vectors, transformed plants and products thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE296355T1 true ATE296355T1 (de) | 2005-06-15 |
Family
ID=27368820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98935230T ATE296355T1 (de) | 1997-08-07 | 1998-08-05 | Universelle integrations- und expressionsvektoren für chloroplasten, transformierte pflanzen und produkte hiervon |
Country Status (12)
Country | Link |
---|---|
US (1) | US7803991B2 (de) |
EP (2) | EP2319933B1 (de) |
JP (1) | JP2002524023A (de) |
CN (1) | CN1262661C (de) |
AT (1) | ATE296355T1 (de) |
AU (1) | AU748210B2 (de) |
BR (1) | BR9815611B1 (de) |
CA (1) | CA2299609C (de) |
DE (1) | DE69830317T3 (de) |
ES (2) | ES2244073T5 (de) |
NZ (1) | NZ502742A (de) |
WO (1) | WO1999010513A1 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110179530A1 (en) * | 2001-01-23 | 2011-07-21 | University Of Central Florida Research Foundation, Inc. | Pharmaceutical Proteins, Human Therapeutics, Human Serum Albumin Insulin, Native Cholera Toxin B Subunit on Transgenic Plastids |
US7741536B2 (en) | 1997-08-07 | 2010-06-22 | University Of Central Florida Research Foundation, Inc. | Expression of human serum albumin in plastids |
WO2001072959A2 (en) * | 2000-03-01 | 2001-10-04 | Auburn University | Plastid transformation vectors for expressing human proteins in plants |
US20100251425A9 (en) * | 1998-05-15 | 2010-09-30 | University Of Central Florida | Expression of human interferon in transgenic chloroplasts |
PT1097211E (pt) | 1998-07-10 | 2007-07-12 | Calgene Llc | Expressão de péptidos eucarióticos em plastos vegetais |
US6512162B2 (en) | 1998-07-10 | 2003-01-28 | Calgene Llc | Expression of eukaryotic peptides in plant plastids |
GB9821303D0 (en) * | 1998-10-01 | 1998-11-25 | Novartis Ag | Organic compounds |
TR200101032T2 (tr) * | 1998-10-07 | 2001-10-22 | Syngenta Participations Ag | Bitkilerdeki sağaltıcı yönden aktif proteinler. |
US6541682B1 (en) * | 1998-11-12 | 2003-04-01 | Calgene Llc | Plastid transformation of solanaceous plants |
ES2262514T3 (es) | 1999-04-29 | 2006-12-01 | Syngenta Limited | Plantas resistentes a herbicidas. |
IL146064A0 (en) * | 1999-04-29 | 2002-07-25 | Marlow Foods Ltd | Herbicide resistant plants |
PL356648A1 (en) * | 1999-04-29 | 2004-06-28 | Syngenta Ltd | Herbicide resistant plants |
AR024934A1 (es) * | 1999-07-27 | 2002-10-30 | Novartis Ag | Genes quimericos |
US20030041353A1 (en) * | 2001-04-18 | 2003-02-27 | Henry Daniell | Mutiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants |
WO2001064850A1 (en) * | 2000-02-29 | 2001-09-07 | Auburn University | Genetic engineering of drought tolerance via a plastid genome |
CA2401957A1 (en) * | 2000-02-29 | 2001-09-07 | University Of Central Florida | Expression of an antimicrobial peptide via the plastid genome to control phytopathogenic bacteria |
EP1263281B1 (de) * | 2000-02-29 | 2012-04-11 | Auburn University | Mehrfache genexpression zur einrichtung von neuen synthesewegen und überexpression von fremdproteinen in pflanzen |
EP1268832A4 (de) * | 2000-02-29 | 2003-04-02 | Univ Auburn | Herstellung von antikörpern in transgenen plastiden |
AU2001245359A1 (en) * | 2000-03-02 | 2001-09-12 | Auburn University | Marker free transgenic plants: engineering the chloroplast genome without the use of antibiotic selection |
US20020137214A1 (en) | 2001-04-18 | 2002-09-26 | Henry Daniell | Marker free transgenic plants engineering the chloroplast genome without the use of antibiotic selection |
WO2001081605A2 (en) * | 2000-04-26 | 2001-11-01 | Monsanto Technology Llc | Method for the transformation of plant cell plastids |
GB2364705A (en) * | 2000-07-14 | 2002-02-06 | Icgeb | Fusion protein expression in plastids |
WO2003054189A2 (de) | 2001-12-20 | 2003-07-03 | Sungene Gmbh & Co. Kgaa | Verfahren zur transformation von pflanzlichen plastiden |
EP1456390B1 (de) | 2001-12-26 | 2011-03-02 | University Of Central Florida | Expression von schutzantigenen in transgenen chloroplasten und herstellung verbesserter impfstoffe |
US7354760B2 (en) | 2001-12-26 | 2008-04-08 | University Of Central Florida Research Foundation, Inc. | Expression of protective antigens in transgenic chloroplasts |
US9267144B2 (en) * | 2002-01-23 | 2016-02-23 | Monsanto Technology Llc | Plastid transformation of maize |
US20060095982A1 (en) * | 2002-07-03 | 2006-05-04 | University Of Central Florida | Phytoremediation of contaminant compounds via chloroplast genetic engineering |
JP2005532069A (ja) | 2002-07-03 | 2005-10-27 | ユニバーシティ オブ セントラル フロリダ | 体細胞胚形成を介した色素体遺伝子操作 |
CA2491639A1 (en) * | 2002-07-03 | 2004-01-15 | University Of Central Florida | Expression of the human igf-1 in transgenic plastids |
US7645918B2 (en) * | 2002-08-08 | 2010-01-12 | Rijk Zwaan Zaadteelt En Zaadhandel B.V. | Method of plastid transformation in asteraceae, vector for use therein and plants thus obtained |
FR2848064B1 (fr) * | 2002-12-06 | 2006-01-13 | Bayer Cropscience Sa | Plantes legumineuses transplastomiques fertiles |
US7560611B2 (en) | 2003-08-05 | 2009-07-14 | Monsanto Technology Llc | Method and apparatus for substantially isolating plant tissues |
US7150993B2 (en) | 2003-08-05 | 2006-12-19 | Monsanto Technology Llc | Method for excision of plant embryos for transformation |
WO2005070066A2 (en) * | 2004-01-08 | 2005-08-04 | Dow Agrosciences Llc | Chlorophyllous totipotent cell cultures |
CA2557668A1 (en) | 2004-02-27 | 2005-09-22 | The Dow Chemical Company | High efficiency peptide production in plant cells |
PL2308977T5 (pl) | 2004-04-30 | 2017-10-31 | Dow Agrosciences Llc | Nowy gen odporności na herbicydy |
CN101014711A (zh) | 2004-06-25 | 2007-08-08 | 阿尔特生物科学公司 | 植物中组织因数的制造 |
FR2880356B1 (fr) * | 2005-01-05 | 2007-04-06 | Bayer Cropscience Sa Sa | Plantes transplastomiques exemptes du gene marqueur de selection |
EP1885173A4 (de) | 2005-05-27 | 2009-02-18 | Univ Central Florida | Für die expression pharmazeutischer proteine entwickelte chloroplaste |
ES2612119T3 (es) | 2005-10-28 | 2017-05-12 | Dow Agrosciences Llc | Nuevos genes de resistencia a herbicidas |
KR100740694B1 (ko) * | 2006-02-09 | 2007-07-18 | 한국생명공학연구원 | 색소체 게놈 내에 삽입된 외래유전자의 이차 재조합을방지하기 위한 벡터개발 |
WO2008112628A2 (en) | 2007-03-09 | 2008-09-18 | Monsanto Technology Llc | Preparation and use of plant embryo explants for transformation |
AU2008232543B2 (en) | 2007-03-30 | 2013-01-17 | University Of Central Florida Research Foundation, Inc. | Chloroplasts engineered to express pharmaceutical proteins in edible plants |
WO2009045550A2 (en) * | 2007-10-05 | 2009-04-09 | Sapphire Energy | System for capturing and modifying large pieces of genomic dna and constructing organisms with synthetic chloroplasts |
US8314222B2 (en) | 2007-10-05 | 2012-11-20 | Sapphire Energy, Inc. | System for capturing and modifying large pieces of genomic DNA and constructing organisms with chloroplasts |
US10689633B2 (en) | 2008-02-29 | 2020-06-23 | The Trustees Of The University Of Pennsylvania | Expression of β-mannanase in chloroplasts and its utilization in lignocellulosic woody biomass hydrolysis |
JP5320782B2 (ja) * | 2008-03-24 | 2013-10-23 | 独立行政法人農業生物資源研究所 | 植物色素体への遺伝子導入法 |
AR074941A1 (es) | 2009-01-07 | 2011-02-23 | Bayer Cropscience Sa | Plantas transplastomicas exentas de marcador de seleccion |
US9724400B2 (en) | 2009-11-09 | 2017-08-08 | The Trustees Of The University Of Pennsylvania | Administration of plant expressed oral tolerance agents |
US20110154541A1 (en) * | 2009-11-24 | 2011-06-23 | Technion Research And Development Foundation Ltd. | Bio-engineered photosystems |
CN102618566B (zh) * | 2011-01-31 | 2014-01-08 | 中国科学院海洋研究所 | 一种构建亚心型扁藻叶绿体表达系统的方法 |
US9303270B2 (en) | 2011-07-22 | 2016-04-05 | Ricetec Aktiengesellschaft | Rice resistant to HPPD and accase inhibiting herbicides |
PH12014500183B1 (en) | 2011-07-22 | 2022-02-16 | Ricetec Inc | Methods and compositions to produce rice resistant to accase inhibitors |
EP2770991B9 (de) | 2011-10-24 | 2017-01-25 | The Trustees Of The University Of Pennsylvania | Oral verabreichtes plastidexprimiertes choleratoxin-b-untereinheit-exendin 4 zur verwendung in der behandlung von typ-2-diabetes |
BR112015009340A2 (pt) * | 2012-10-24 | 2017-08-29 | Jay Bendich Arnold | Transformação de plastídeo usando vetores de dna lineares |
CN107810271B (zh) * | 2014-11-20 | 2021-09-28 | 耶路撒冷希伯来大学伊萨姆研发公司 | 用于在植物细胞中生产具有改变的糖基化模式的多肽的组合物和方法 |
WO2016134377A1 (en) * | 2015-02-21 | 2016-08-25 | The Trustees Of The University Of Pennsylvania | Compositions and methods thereof for down-regulation of genes following oral delivery of an rnai molecule bioencapsulated within plant cells |
CN104946656B (zh) * | 2015-06-08 | 2018-08-17 | 吉林省农业科学院 | 一种人源碱性成纤维细胞生长因子、烟草叶绿体表达载体及生产方法 |
JP6696806B2 (ja) * | 2015-08-28 | 2020-05-20 | 本田技研工業株式会社 | プラスチド形質転換体の製造方法 |
WO2017038835A2 (en) * | 2015-08-28 | 2017-03-09 | Honda Motor Co., Ltd. | Method of producing plastid transformants |
WO2018024906A1 (en) | 2016-08-05 | 2018-02-08 | Ricetec Aktiengesellschaft | Methods and compositions for combinations of mutations associated with herbicide resistance/tolerance in rice |
CN107267538B (zh) * | 2017-06-12 | 2019-11-05 | 湖北大学 | 一种植物质体表达载体的构建方法及应用 |
CN110042119A (zh) * | 2018-01-17 | 2019-07-23 | 吉林省农业科学院 | 一种水稻叶绿体遗传转化方法 |
CN112858682B (zh) * | 2019-11-27 | 2023-06-02 | 广东唯实生物技术有限公司 | 用于尿微量白蛋白的检测试纸条及其制备方法、检测试剂盒和检测方法 |
JPWO2021193688A1 (de) * | 2020-03-25 | 2021-09-30 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US555038A (en) * | 1896-02-18 | dudley | ||
US4956282A (en) | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
EP0251654A2 (de) | 1986-06-23 | 1988-01-07 | Biotechnica International, Inc. | Transformation von Chloroplasten |
US5693507A (en) | 1988-09-26 | 1997-12-02 | Auburn University | Genetic engineering of plant chloroplasts |
US5932479A (en) | 1988-09-26 | 1999-08-03 | Auburn University | Genetic engineering of plant chloroplasts |
NL8901932A (nl) * | 1989-07-26 | 1991-02-18 | Mogen Int | Produktie van heterologe eiwitten in planten of plantecellen. |
US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
-
1998
- 1998-08-05 NZ NZ502742A patent/NZ502742A/en unknown
- 1998-08-05 WO PCT/IB1998/001199 patent/WO1999010513A1/en active IP Right Grant
- 1998-08-05 AT AT98935230T patent/ATE296355T1/de not_active IP Right Cessation
- 1998-08-05 DE DE69830317T patent/DE69830317T3/de not_active Expired - Lifetime
- 1998-08-05 JP JP2000507821A patent/JP2002524023A/ja active Pending
- 1998-08-05 AU AU84573/98A patent/AU748210B2/en not_active Expired
- 1998-08-05 EP EP10181990.2A patent/EP2319933B1/de not_active Expired - Lifetime
- 1998-08-05 EP EP98935230A patent/EP1002115B9/de not_active Expired - Lifetime
- 1998-08-05 CA CA2299609A patent/CA2299609C/en not_active Expired - Lifetime
- 1998-08-05 ES ES98935230T patent/ES2244073T5/es not_active Expired - Lifetime
- 1998-08-05 BR BRPI9815611-0B1A patent/BR9815611B1/pt not_active IP Right Cessation
- 1998-08-05 CN CNB98808127XA patent/CN1262661C/zh not_active Expired - Lifetime
- 1998-08-05 ES ES05011140T patent/ES2401438T3/es not_active Expired - Lifetime
-
2006
- 2006-04-24 US US11/379,833 patent/US7803991B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1002115B1 (de) | 2005-05-25 |
JP2002524023A (ja) | 2002-08-06 |
DE69830317D1 (de) | 2005-06-30 |
BR9815611A (pt) | 2002-07-30 |
WO1999010513A1 (en) | 1999-03-04 |
EP1002115B2 (de) | 2008-09-03 |
AU748210B2 (en) | 2002-05-30 |
EP1002115B9 (de) | 2008-12-03 |
BR9815611B1 (pt) | 2013-09-17 |
NZ502742A (en) | 2004-04-30 |
ES2244073T5 (es) | 2009-02-01 |
CN1262661C (zh) | 2006-07-05 |
EP1002115A1 (de) | 2000-05-24 |
DE69830317T3 (de) | 2009-03-19 |
ES2244073T3 (es) | 2005-12-01 |
EP2319933A1 (de) | 2011-05-11 |
EP2319933B1 (de) | 2014-10-15 |
US7803991B2 (en) | 2010-09-28 |
US20080189803A1 (en) | 2008-08-07 |
CA2299609A1 (en) | 1999-03-04 |
DE69830317T2 (de) | 2006-02-02 |
ES2401438T3 (es) | 2013-04-19 |
CN1276835A (zh) | 2000-12-13 |
AU8457398A (en) | 1999-03-16 |
CA2299609C (en) | 2011-12-06 |
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