ATE291016T1 - Amidinophenylalaninderivate als thrombininhibitoren - Google Patents
Amidinophenylalaninderivate als thrombininhibitorenInfo
- Publication number
- ATE291016T1 ATE291016T1 AT01272199T AT01272199T ATE291016T1 AT E291016 T1 ATE291016 T1 AT E291016T1 AT 01272199 T AT01272199 T AT 01272199T AT 01272199 T AT01272199 T AT 01272199T AT E291016 T1 ATE291016 T1 AT E291016T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombin inhibitors
- amidinophenylalanine derivatives
- amidinophenylalanine
- derivatives
- compounds
- Prior art date
Links
- 229940122388 Thrombin inhibitor Drugs 0.000 title abstract 2
- 239000003868 thrombin inhibitor Substances 0.000 title abstract 2
- MVTHUEOHHHQQKY-QMMMGPOBSA-N (2s)-2-(diaminomethylideneamino)-3-phenylpropanoic acid Chemical class NC(N)=N[C@H](C(O)=O)CC1=CC=CC=C1 MVTHUEOHHHQQKY-QMMMGPOBSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
- C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI200000326A SI20743A (sl) | 2000-12-22 | 2000-12-22 | Novi trombinski inhibitorji |
| PCT/IB2001/002600 WO2002051824A1 (en) | 2000-12-22 | 2001-12-20 | Amidinophenylalanine derivatives as thrombin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE291016T1 true ATE291016T1 (de) | 2005-04-15 |
Family
ID=20432799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01272199T ATE291016T1 (de) | 2000-12-22 | 2001-12-20 | Amidinophenylalaninderivate als thrombininhibitoren |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7285547B2 (de) |
| EP (1) | EP1355894B1 (de) |
| JP (1) | JP4390453B2 (de) |
| AT (1) | ATE291016T1 (de) |
| DE (1) | DE60109498T2 (de) |
| DK (1) | DK1355894T3 (de) |
| ES (1) | ES2240345T3 (de) |
| PT (1) | PT1355894E (de) |
| SI (1) | SI20743A (de) |
| WO (1) | WO2002051824A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| GB0523539D0 (en) * | 2005-11-18 | 2005-12-28 | Lek Tovarna Farmacevtskih | New use of organic compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9322976D0 (en) * | 1993-11-08 | 1994-01-05 | Pfizer Ltd | Therapeutic agents |
-
2000
- 2000-12-22 SI SI200000326A patent/SI20743A/sl not_active IP Right Cessation
-
2001
- 2001-12-20 US US10/433,358 patent/US7285547B2/en not_active Expired - Fee Related
- 2001-12-20 EP EP01272199A patent/EP1355894B1/de not_active Expired - Lifetime
- 2001-12-20 DK DK01272199T patent/DK1355894T3/da active
- 2001-12-20 PT PT01272199T patent/PT1355894E/pt unknown
- 2001-12-20 JP JP2002552919A patent/JP4390453B2/ja not_active Expired - Fee Related
- 2001-12-20 ES ES01272199T patent/ES2240345T3/es not_active Expired - Lifetime
- 2001-12-20 WO PCT/IB2001/002600 patent/WO2002051824A1/en active IP Right Grant
- 2001-12-20 DE DE60109498T patent/DE60109498T2/de not_active Expired - Lifetime
- 2001-12-20 AT AT01272199T patent/ATE291016T1/de active
-
2007
- 2007-09-12 US US11/854,532 patent/US20080004256A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080004256A1 (en) | 2008-01-03 |
| EP1355894A1 (de) | 2003-10-29 |
| US20040048851A1 (en) | 2004-03-11 |
| DE60109498T2 (de) | 2006-04-13 |
| DK1355894T3 (da) | 2005-07-11 |
| DE60109498D1 (en) | 2005-04-21 |
| PT1355894E (pt) | 2005-08-31 |
| SI20743A (sl) | 2002-06-30 |
| JP2004516317A (ja) | 2004-06-03 |
| US7285547B2 (en) | 2007-10-23 |
| JP4390453B2 (ja) | 2009-12-24 |
| ES2240345T3 (es) | 2005-10-16 |
| WO2002051824A1 (en) | 2002-07-04 |
| EP1355894B1 (de) | 2005-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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