[go: up one dir, main page]

ATE290546T1 - Tachykinin antagoniste - Google Patents

Tachykinin antagoniste

Info

Publication number
ATE290546T1
ATE290546T1 AT97953927T AT97953927T ATE290546T1 AT E290546 T1 ATE290546 T1 AT E290546T1 AT 97953927 T AT97953927 T AT 97953927T AT 97953927 T AT97953927 T AT 97953927T AT E290546 T1 ATE290546 T1 AT E290546T1
Authority
AT
Austria
Prior art keywords
tachykinin antagonist
tachykinin
antagonist
Prior art date
Application number
AT97953927T
Other languages
English (en)
Inventor
Christopher Simon John Walpole
Mahavir Prashad
Denis Har
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE290546T1 publication Critical patent/ATE290546T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/22Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97953927T 1997-01-14 1997-12-29 Tachykinin antagoniste ATE290546T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9700597.9A GB9700597D0 (en) 1997-01-14 1997-01-14 Organic compounds
PCT/EP1997/007307 WO1998031704A2 (en) 1997-01-14 1997-12-29 Tachykinin antagonists

Publications (1)

Publication Number Publication Date
ATE290546T1 true ATE290546T1 (de) 2005-03-15

Family

ID=10805904

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97953927T ATE290546T1 (de) 1997-01-14 1997-12-29 Tachykinin antagoniste

Country Status (14)

Country Link
US (1) US6107293A (de)
EP (1) EP0964867B1 (de)
JP (2) JP4306804B2 (de)
AR (1) AR011521A1 (de)
AT (1) ATE290546T1 (de)
AU (1) AU5764298A (de)
CA (1) CA2278057C (de)
CO (1) CO4950614A1 (de)
DE (1) DE69732715T2 (de)
ES (1) ES2239368T3 (de)
GB (1) GB9700597D0 (de)
PT (1) PT964867E (de)
WO (1) WO1998031704A2 (de)
ZA (1) ZA98256B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6426331B1 (en) 1998-07-08 2002-07-30 Tularik Inc. Inhibitors of STAT function
GB9815696D0 (en) * 1998-07-20 1998-09-16 Pfizer Ltd Heterocyclics
KR100699404B1 (ko) 1999-02-18 2007-03-23 가켄 세야쿠 가부시키가이샤 성장 호르몬 분비촉진제로서의 신규 아미드 유도체
AU2000249828A1 (en) * 2000-05-03 2001-11-12 Taisho Pharmaceutical Co. Ltd. Stat4 and stat6 binding dipeptide derivatives
US6884782B2 (en) 2000-11-08 2005-04-26 Amgen Inc. STAT modulators
US20070219214A1 (en) * 2006-02-01 2007-09-20 Solvay Pharmaceuticals Gmbh Dual NK2/NK3-antagonists, pharmaceutical compositions comprising them, and processes for their preparation
WO2008047709A1 (en) 2006-10-16 2008-04-24 Lion Corporation Nk1 receptor antagonist composition
US9782397B2 (en) 2011-07-04 2017-10-10 Irbm Science Park S.P.A. Treatment of corneal neovascularization
EP3758688B1 (de) 2018-02-26 2024-03-27 Ospedale San Raffaele S.r.l. Nk-1-antagonisten zur verwendung bei der behandlung von augenschmerzen
US20230134843A1 (en) 2020-03-11 2023-05-04 Ospedale San Raffaele S.R.L. Treatment of stem cell deficiency

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210669A (en) * 1983-12-27 1988-05-30 Syntex Inc Benzoxazin-4-one derivatives and pharmaceutical compositions
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
FR2719312B1 (fr) * 1994-04-28 1996-06-14 Adir Nouveau pseudopeptides dérivés de neurokinines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
AU5764298A (en) 1998-08-07
JP2000516257A (ja) 2000-12-05
DE69732715D1 (de) 2005-04-14
CO4950614A1 (es) 2000-09-01
WO1998031704A2 (en) 1998-07-23
JP4306804B2 (ja) 2009-08-05
CA2278057C (en) 2004-05-04
DE69732715T2 (de) 2006-04-13
JP2006089499A (ja) 2006-04-06
GB9700597D0 (en) 1997-03-05
WO1998031704A3 (en) 1998-09-11
PT964867E (pt) 2005-07-29
CA2278057A1 (en) 1998-07-23
JP3817256B2 (ja) 2006-09-06
EP0964867A2 (de) 1999-12-22
AR011521A1 (es) 2000-08-30
EP0964867B1 (de) 2005-03-09
ES2239368T3 (es) 2005-09-16
US6107293A (en) 2000-08-22
ZA98256B (en) 1998-07-14

Similar Documents

Publication Publication Date Title
BR9509997A (pt) Antagonista de taquiquinina
NO951613D0 (no) Ikke-peptidyl tachykinin reseptorantagonister
ID22500A (id) Turunan sulfonamida
ATE250583T1 (de) Substituierte 3-cyanochinoline
ID24430A (id) Turunan-turunan benzamidina
DE69831181D1 (de) Positionsbestimmung
EE9600186A (et) Neurokiniini (tahhüülkiniini) antagonistid
DE69826891D1 (de) Piperidinderivate
DE69626220D1 (de) 3-azetidinylalkylpiperidine oder -pyrrolidine als tachykinin antagonisten
NO994548D0 (no) Rekkverk
DE59813487D1 (de) Substituierte 4-benzoyl-pyrazole
ATE290546T1 (de) Tachykinin antagoniste
ID24468A (id) 2-asilaminopropanamina sebagai antagonis reseptor tachykinin
DE69735811D1 (de) Piperazinoderivate als neurokinin-antagonisten
DK0983266T3 (da) Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider
DE69820505D1 (de) Lärmschutzwand
DK1032733T3 (da) Støjskærm
ID24309A (id) 2-asilaminopropanamina sebagai antagonis reseptor tachykinin
DK0960100T3 (da) Substituerede 4-benzoyl-pyrazoler
ID26508A (id) Oksim-oksim tersubstitusi sebagai antagonis-antagonis neurokinin
DE69814442D1 (de) Strukturerkennung
ID20897A (id) Susunan penutup-rapat
DE59807877D1 (de) Substituierte 4-benzoyl-pyrazole
ID24079A (id) Aminoheteroksiklilamida tersubstitusi
DK0964867T3 (da) Tachykininantagonister

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0964867

Country of ref document: EP

REN Ceased due to non-payment of the annual fee