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ATE290077T1 - Regulierte gene und ihre verwendungen - Google Patents

Regulierte gene und ihre verwendungen

Info

Publication number
ATE290077T1
ATE290077T1 AT96932771T AT96932771T ATE290077T1 AT E290077 T1 ATE290077 T1 AT E290077T1 AT 96932771 T AT96932771 T AT 96932771T AT 96932771 T AT96932771 T AT 96932771T AT E290077 T1 ATE290077 T1 AT E290077T1
Authority
AT
Austria
Prior art keywords
regulated genes
protein
therapy
mitogenic activity
purposes
Prior art date
Application number
AT96932771T
Other languages
English (en)
Inventor
Salvatore Oliviero
Original Assignee
Univ Siena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290077(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9519928.7A external-priority patent/GB9519928D0/en
Priority claimed from GBGB9612368.2A external-priority patent/GB9612368D0/en
Application filed by Univ Siena filed Critical Univ Siena
Application granted granted Critical
Publication of ATE290077T1 publication Critical patent/ATE290077T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
AT96932771T 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen ATE290077T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9519928.7A GB9519928D0 (en) 1995-09-29 1995-09-29 Regulated genes and uses thereof
GBGB9612368.2A GB9612368D0 (en) 1996-06-13 1996-06-13 Regulated genes and uses thereof
PCT/IB1996/001113 WO1997012972A2 (en) 1995-09-29 1996-09-30 Regulated genes and uses thereof

Publications (1)

Publication Number Publication Date
ATE290077T1 true ATE290077T1 (de) 2005-03-15

Family

ID=26307843

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05001932T ATE459715T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen
AT96932771T ATE290077T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05001932T ATE459715T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Country Status (11)

Country Link
US (1) US8383788B2 (de)
EP (2) EP0853668B2 (de)
JP (1) JP4086315B2 (de)
AT (2) ATE459715T1 (de)
AU (1) AU7142996A (de)
CA (1) CA2230957A1 (de)
DE (2) DE69634412T3 (de)
ES (2) ES2239338T5 (de)
IL (1) IL123649A0 (de)
NO (1) NO981353D0 (de)
WO (1) WO1997012972A2 (de)

Families Citing this family (33)

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Publication number Priority date Publication date Assignee Title
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7423125B2 (en) 1995-08-01 2008-09-09 Vegenics Limited Antibodies to VEGF-C
WO1997009427A1 (en) 1995-09-08 1997-03-13 Genentech, Inc. Vegf-related protein
ES2239338T5 (es) 1995-09-29 2013-05-31 Vegenics Pty Ltd Genes regulados y sus usos
DE69733204T3 (de) 1996-07-15 2012-03-08 Chugai Seiyaku K.K. Neuartige vegf-ähnliche faktoren
EP2107109B1 (de) * 1996-08-23 2012-06-20 Vegenics Pty Ltd Rekombinanter Vaskularer Endothelzellen Wachstumsfaktor D (VEGF-D)
AU5439998A (en) * 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
ATE395928T1 (de) * 1997-12-24 2008-06-15 Ludwig Inst Cancer Res Expressionsvektoren und zellinien zur expression von vaskulärem wachstumsfaktor d, sowie verfahren zur behandlung von melanomen
DE19847422C1 (de) * 1998-10-14 2000-01-13 Forschungszentrum Juelich Gmbh Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
ATE404668T1 (de) 1998-12-07 2008-08-15 Zymogenetics Inc Wachstumsfaktor-homologe zvegf-3
CA2381985A1 (en) * 1999-08-16 2001-02-22 Universita'degli Studi Di Siena Vegf-d and angiogenic use thereof
US6965010B2 (en) * 2000-02-25 2005-11-15 Licentia, Ltd. Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
AU2002248372B8 (en) 2001-01-19 2008-03-20 Vegenics Limited FLT4(VEGFR-3) as a target for tumor imaging and anti-tumor therapy
CA2453161A1 (en) * 2001-07-12 2003-01-23 Ludwig Institute For Cancer Research Lymphatic endothelial cells materials and methods
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
WO2005011722A2 (en) * 2003-06-12 2005-02-10 Ludwig Institute For Cancer Research Use of vegf-c or vegf-d in reconstructive surgery
WO2005016963A2 (en) * 2003-06-12 2005-02-24 Ludwig Institute For Cancer Research Heparin binding veger-3 ligands
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
ITRM20050367A1 (it) * 2005-07-08 2007-01-09 Univ Siena Uso del vegf-d o di suoi frammenti funzionalmente attivi per la ricostruzione o per la riparazione ossea.
ES2363758T3 (es) 2005-08-15 2011-08-16 Vegenics Pty Ltd Vegf y pdgf modificados con propiedades angiogénicas mejoradas.
EP2125895B1 (de) 2007-02-02 2015-04-08 Vegenics Pty Ltd Vegf-rezeptorantagonisten zur behandlung von allommunität bei organtransplantationen und atherosklerose
US8571840B2 (en) * 2007-03-28 2013-10-29 Autodesk, Inc. Constraint reduction for dynamic simulation
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
EP2800602B1 (de) 2012-01-06 2017-08-02 Emboline, Inc. Integrierte embolieschutzvorrichtungen
RS60026B1 (sr) 2013-02-18 2020-04-30 Vegenics Pty Ltd Molekuli koji vezuju ligande i njihove upotrebe
US20190016770A1 (en) * 2015-08-25 2019-01-17 Histide Ag Compounds for inducing tissue formation and uses thereof
KR20180043317A (ko) 2015-08-25 2018-04-27 히스티드 아게 조직 형성 유도용 화합물 및 그것의 용도
EP3923861B1 (de) 2019-02-13 2024-12-18 Emboline, Inc. Katheter mit integrierter embolieschutzvorrichtung

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135983D0 (da) 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5968778A (en) * 1989-01-12 1999-10-19 Jurgen Hoppe PDGF-AB, preparation process and pharmaceuticals containing them
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
JP3024311B2 (ja) 1991-10-03 2000-03-21 味の素株式会社 Ｉｌ−２受容体重鎖に結合するポリペプチド
JPH05271294A (ja) 1992-01-24 1993-10-19 Japan Found Cancer Res ヒトプロヒビチンおよびそれをコードするｄｎａ
JP2571197B2 (ja) 1992-07-27 1997-01-16 ファイザー インク． アゲレノプシス・アペルタ由来のカルシウムチャンネル阻害ポリペプチド
AU696764B2 (en) * 1994-03-08 1998-09-17 Human Genome Sciences, Inc. Vascular endothelial growth factor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US6221839B1 (en) * 1994-11-14 2001-04-24 Helsinki University Licensing Ltd. Oy FIt4 ligand and methods of use
US6645933B1 (en) 1995-08-01 2003-11-11 Helsinki University Licensing Ltd. Oy Receptor ligand VEGF-C
JPH08185216A (ja) 1994-12-28 1996-07-16 Meidensha Corp 工具姿勢パラメータ設定方法及びロボット制御装置
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
CN1194090C (zh) 1995-03-02 2005-03-23 阿穆拉德业务有限公司 一种新的生长因子和编码这种生长因子的基因序列
CA2224002A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
ES2239338T5 (es) 1995-09-29 2013-05-31 Vegenics Pty Ltd Genes regulados y sus usos
DE69733204T3 (de) * 1996-07-15 2012-03-08 Chugai Seiyaku K.K. Neuartige vegf-ähnliche faktoren
EP2107109B1 (de) 1996-08-23 2012-06-20 Vegenics Pty Ltd Rekombinanter Vaskularer Endothelzellen Wachstumsfaktor D (VEGF-D)
AU5439998A (en) 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
WO1998036052A1 (en) 1997-02-18 1998-08-20 Ludwig Institute For Cancer Research Transgenic animal with recombinant vascular endothelial growth factor b (vegf-b) dna and uses thereof
ATE322909T1 (de) * 1998-12-21 2006-04-15 Ludwig Inst Cancer Res Antikörper gegen verkürzten vegf-d und deren verwendungen
CA2381985A1 (en) 1999-08-16 2001-02-22 Universita'degli Studi Di Siena Vegf-d and angiogenic use thereof
NZ587143A (en) 2008-02-12 2011-07-29 Dow Agrosciences Llc Pesticidal compositions

Also Published As

Publication number Publication date
EP1553182B1 (de) 2010-03-03
ES2341864T3 (es) 2010-06-29
WO1997012972A2 (en) 1997-04-10
DE69638142D1 (de) 2010-04-15
NO981353L (no) 1998-03-25
JP4086315B2 (ja) 2008-05-14
IL123649A0 (en) 1998-10-30
ES2239338T3 (es) 2005-09-16
ATE459715T1 (de) 2010-03-15
DE69634412T2 (de) 2005-12-15
EP0853668B2 (de) 2013-03-06
EP0853668A2 (de) 1998-07-22
EP0853668B1 (de) 2005-03-02
JP2001501442A (ja) 2001-02-06
CA2230957A1 (en) 1997-04-10
NO981353D0 (no) 1998-03-25
ES2239338T5 (es) 2013-05-31
US20020123481A1 (en) 2002-09-05
US8383788B2 (en) 2013-02-26
WO1997012972A3 (en) 1997-06-12
AU7142996A (en) 1997-04-28
EP1553182A2 (de) 2005-07-13
EP1553182A3 (de) 2008-03-05
DE69634412D1 (de) 2005-04-07
DE69634412T3 (de) 2013-07-04

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