ATE286387T1 - Clarithromycin enthaltende zubereitung mit verlängerter freisetzung - Google Patents
Clarithromycin enthaltende zubereitung mit verlängerter freisetzungInfo
- Publication number
- ATE286387T1 ATE286387T1 AT01971528T AT01971528T ATE286387T1 AT E286387 T1 ATE286387 T1 AT E286387T1 AT 01971528 T AT01971528 T AT 01971528T AT 01971528 T AT01971528 T AT 01971528T AT E286387 T1 ATE286387 T1 AT E286387T1
- Authority
- AT
- Austria
- Prior art keywords
- clarithromycin
- sustained release
- extended release
- preparation containing
- release preparation
- Prior art date
Links
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 4
- 229960002626 clarithromycin Drugs 0.000 title abstract 4
- 238000013265 extended release Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 abstract 4
- 239000012730 sustained-release form Substances 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000008188 pellet Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE0000112 | 2000-09-22 | ||
| PCT/BE2001/000164 WO2002024174A2 (en) | 2000-09-22 | 2001-09-21 | Sustained release composition containing clarithromycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286387T1 true ATE286387T1 (de) | 2005-01-15 |
Family
ID=3862551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01971528T ATE286387T1 (de) | 2000-09-22 | 2001-09-21 | Clarithromycin enthaltende zubereitung mit verlängerter freisetzung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040048814A1 (de) |
| EP (1) | EP1318792B1 (de) |
| AT (1) | ATE286387T1 (de) |
| AU (1) | AU2001291526A1 (de) |
| CA (1) | CA2423172A1 (de) |
| DE (1) | DE60108255T2 (de) |
| ES (1) | ES2234885T3 (de) |
| PT (1) | PT1318792E (de) |
| WO (1) | WO2002024174A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6565882B2 (en) * | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
| US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
| US20020068078A1 (en) * | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
| US6541014B2 (en) * | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
| US7037523B2 (en) | 2001-11-02 | 2006-05-02 | Wockhardt Limited | Controlled release compositions for macrolide antimicrobial agents |
| US7137696B2 (en) * | 2003-01-09 | 2006-11-21 | Con-Trol-Cure, Inc. | Ink jet UV curing |
| WO2005004919A2 (en) * | 2003-07-02 | 2005-01-20 | Eurand, Inc. | Extended release systems for macrolide antibiotics |
| EP1648407A4 (de) * | 2003-07-21 | 2011-08-31 | Middlebrook Pharmaceuticals Inc | Antibiotisches produkt, seine verwendung und formulierung |
| EP1648418A4 (de) * | 2003-07-21 | 2011-11-16 | Middlebrook Pharmaceuticals Inc | Antibiotisches produkt, seine verwendung und formulierung |
| AU2004258949B2 (en) * | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
| WO2005016311A1 (en) * | 2003-08-11 | 2005-02-24 | Advancis Pharmaceutical Corporation | Robust pellet |
| EP1653924A4 (de) * | 2003-08-12 | 2009-09-09 | Middlebrook Pharmaceuticals In | Antibiotisches produkt, seine verwendung und formulierung |
| US8246996B2 (en) * | 2003-08-29 | 2012-08-21 | Shionogi Inc. | Antibiotic product, use and formulation thereof |
| JP2007513869A (ja) * | 2003-09-15 | 2007-05-31 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
| EP1689368B1 (de) | 2003-12-04 | 2016-09-28 | Bend Research, Inc | Sprüherstarrungsverfahren mit einem extruder zur herstellung von multiteilchenförmigen kristallinen arzneimittelzusammensetzungen |
| US6984403B2 (en) | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
| EP1701705A4 (de) * | 2003-12-24 | 2007-08-08 | Advancis Pharmaceutical Corp | Verbesserte absorption von dosierformen mit modifizierter freisetzung |
| KR101122096B1 (ko) * | 2004-05-20 | 2012-03-15 | 주식회사종근당 | 쓴맛을 차폐하면서 우수한 용출률을 보이는클라리스로마이신의 약제학적 조성물 및 그의 제조 방법 |
| AU2005269981A1 (en) * | 2004-07-02 | 2006-02-09 | Bonck, John A | Tablet for pulsed delivery |
| CN1322866C (zh) * | 2004-10-12 | 2007-06-27 | 广州贝氏药业有限公司 | 一种多单元缓释制剂 |
| FR2879075B1 (fr) * | 2004-12-15 | 2007-01-19 | Adisseo France Sas Soc Par Act | Procede de preparation de granules de principe actif hydrophile par extrusion |
| MX2007007836A (es) | 2004-12-27 | 2007-08-20 | Eisai R&D Man Co Ltd | Metodo para estabilizar un farmaco anti-demencia. |
| KR100676075B1 (ko) | 2005-02-17 | 2007-02-01 | 한국유나이티드제약 주식회사 | 경구투여용 클래리스로마이신 함유 펠렛 제제 |
| US8778924B2 (en) | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
| US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
| US8299052B2 (en) | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US293885A (en) * | 1884-02-19 | Milton jackson | ||
| US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
| US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
| PT744941E (pt) * | 1994-02-16 | 2003-10-31 | Abbott Lab | Processo para preparar formulacoes farmaceuticas de particulas finas |
| AUPO637197A0 (en) * | 1997-04-23 | 1997-05-15 | F.H. Faulding & Co. Limited | Taste-masked pharmaceutical compositions |
| WO2001035930A1 (en) * | 1999-11-16 | 2001-05-25 | Ranbaxy Laboratories Limited | Taste masked oral compositions |
| CA2400818C (en) * | 2000-02-24 | 2009-01-06 | Advancis Pharmaceutical Corporation | Antibiotic and antifungal compositions |
-
2001
- 2001-09-21 ES ES01971528T patent/ES2234885T3/es not_active Expired - Lifetime
- 2001-09-21 WO PCT/BE2001/000164 patent/WO2002024174A2/en active IP Right Grant
- 2001-09-21 PT PT01971528T patent/PT1318792E/pt unknown
- 2001-09-21 DE DE60108255T patent/DE60108255T2/de not_active Expired - Lifetime
- 2001-09-21 AU AU2001291526A patent/AU2001291526A1/en not_active Abandoned
- 2001-09-21 CA CA002423172A patent/CA2423172A1/en not_active Abandoned
- 2001-09-21 AT AT01971528T patent/ATE286387T1/de not_active IP Right Cessation
- 2001-09-21 EP EP01971528A patent/EP1318792B1/de not_active Expired - Lifetime
- 2001-09-21 US US10/380,620 patent/US20040048814A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002024174A2 (en) | 2002-03-28 |
| US20040048814A1 (en) | 2004-03-11 |
| DE60108255T2 (de) | 2005-12-22 |
| EP1318792A2 (de) | 2003-06-18 |
| AU2001291526A1 (en) | 2002-04-02 |
| CA2423172A1 (en) | 2002-03-28 |
| EP1318792B1 (de) | 2005-01-05 |
| ES2234885T3 (es) | 2005-07-01 |
| DE60108255D1 (de) | 2005-02-10 |
| PT1318792E (pt) | 2005-04-29 |
| WO2002024174A3 (en) | 2002-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |