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ATE283707T1 - Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem - Google Patents

Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem

Info

Publication number
ATE283707T1
ATE283707T1 AT99900173T AT99900173T ATE283707T1 AT E283707 T1 ATE283707 T1 AT E283707T1 AT 99900173 T AT99900173 T AT 99900173T AT 99900173 T AT99900173 T AT 99900173T AT E283707 T1 ATE283707 T1 AT E283707T1
Authority
AT
Austria
Prior art keywords
antibacterial composition
topical application
application containing
faropenem
containing faropenem
Prior art date
Application number
AT99900173T
Other languages
English (en)
Inventor
Masaaki Nomura
Hiromi Sumikawa
Osamu Sugita
Original Assignee
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Pharma Co Ltd
Application granted granted Critical
Publication of ATE283707T1 publication Critical patent/ATE283707T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99900173T 1998-01-13 1999-01-12 Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem ATE283707T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP484598 1998-01-13
PCT/JP1999/000068 WO1999036098A1 (fr) 1998-01-13 1999-01-12 Composition antibacterienne contenant des antibiotiques et destinee a l'administration topique

Publications (1)

Publication Number Publication Date
ATE283707T1 true ATE283707T1 (de) 2004-12-15

Family

ID=11595031

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99900173T ATE283707T1 (de) 1998-01-13 1999-01-12 Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem

Country Status (7)

Country Link
US (3) US6365635B1 (de)
EP (1) EP0966974B1 (de)
KR (1) KR20000076105A (de)
CN (1) CN1133428C (de)
AT (1) ATE283707T1 (de)
DE (1) DE69922296T2 (de)
WO (1) WO1999036098A1 (de)

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CN1198611C (zh) * 1999-09-17 2005-04-27 第一三得利制药株式会社 药物抗菌剂组合物
DE60008497T2 (de) * 1999-10-12 2004-12-02 Daiichi Suntory Pharma Co., Ltd. Arzneimittel zur oralen verabreichung
KR20020068385A (ko) * 1999-12-28 2002-08-27 데이고꾸세이약꾸가부시끼가이샤 소양증 치료용 외용제
JP4653282B2 (ja) * 2000-05-23 2011-03-16 昭和薬品化工株式会社 ミノサイクリン含有組成物
DE60214376T2 (de) 2001-06-15 2007-08-30 Innovent Technology Ltd., Turriff Zusammensetzung zur behandlung von huf- und klauenerkrankungen
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US8778889B2 (en) * 2003-03-10 2014-07-15 The United States Of America As Represented By The Secretary Of The Army Antimicrobial decapeptide oral hygiene treatment
US7494980B2 (en) * 2003-03-10 2009-02-24 The United States Of America As Represented By The Secretary Of The Army Antimicrobial peptide and methods of use thereof
US20050123576A1 (en) * 2003-12-03 2005-06-09 Ilana Lavon Mupirocin compositions for topical use, an improved process of making same and methods of using same
US20060029674A1 (en) * 2004-04-09 2006-02-09 Sever Nancy E Stable amorphous Cefdinir
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
EP1872788B1 (de) * 2005-04-08 2013-05-22 Mie University Topisches mittel zur behandlung von wunden
EP2046801A4 (de) * 2006-07-28 2014-04-16 Hetero Drugs Ltd Feste freie faropenemsäure
US20100179170A1 (en) * 2006-12-05 2010-07-15 Lisa Claire Du Toit Heterogeneously configured multiparticulate gastrointestinal drug delivery system
CA2734687A1 (en) * 2008-08-18 2010-02-25 Nanotherapeutics, Inc. Topical hydrogel composition
CA2811568A1 (en) * 2010-10-08 2012-04-12 Helperby Therapeutics Limited Novel composition
EP2879499B1 (de) 2012-08-06 2018-09-26 Isp Investments Inc. Umweltfreundliche nichtwässrige antimikrobielle zusammensetzung mit tropolon mit 1,3-propandiol oder sorbitancaprylat
US20170239277A1 (en) * 2016-02-23 2017-08-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US10898491B2 (en) 2015-12-18 2021-01-26 Cmpd Licensing, Llc Compositions and methods for treating an infection
US10898455B2 (en) 2016-01-07 2021-01-26 Cmpd Licensing, Llc Urea cream formulations
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11690815B2 (en) 2015-08-05 2023-07-04 Cmpd Licensing Llc Hyperkeratotic skin condition treatments and compositions
US11278590B2 (en) 2015-08-05 2022-03-22 Cmpd Licensing, Llc Compositions and methods for treating nail infections
US11446236B2 (en) 2015-08-05 2022-09-20 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US11202788B2 (en) 2019-08-22 2021-12-21 Nanopharmaceutics, Inc. Topical doxycycline hydrogel with improved long-term stability

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US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0042026B1 (de) 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS5625110A (en) 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
IL58576A (en) 1978-12-18 1985-12-31 Bristol Myers Co 2-substituted and 2,6-disubstituted penem compounds,their preparation and pharmaceutical compositions containing them
US4683226A (en) * 1979-08-01 1987-07-28 Schering Corporation 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids
US4411906A (en) * 1981-11-25 1983-10-25 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates
US4650794A (en) * 1982-04-29 1987-03-17 Merck & Co., Inc. 6-(1-hydroxyethyl)-2-carbamimidoyl-pen-2-em-3-carboxylic acids
US4388310A (en) * 1982-03-01 1983-06-14 Merck & Co., Inc. 6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
US4743598A (en) * 1982-12-06 1988-05-10 Schering Corporation Antibacterial 2-(azacycloalkyl) penems
JPH0234325B2 (ja) 1985-11-22 1990-08-02 Sansutaa Kk Shishushitsukanchiryoyososeibutsu
US4701320A (en) 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases
JPS61130228A (ja) 1984-11-29 1986-06-18 Sunstar Inc ミノサイクリンを安定に配合した組成物
JPH075463B2 (ja) 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
JP2526046B2 (ja) 1986-12-26 1996-08-21 サントリー株式会社 ペネム誘導体、その製造法およびその用途
JP2852687B2 (ja) 1990-04-27 1999-02-03 富山化学工業株式会社 歯周ポケット用徐放性口腔用軟膏
SK280188B6 (sk) * 1990-08-20 1999-09-10 Suntory Limited Penem-deriváty a antibiotický prostriedok ktorý ic
DE69232598T2 (de) * 1991-02-01 2002-11-21 Suntory Limited, Osaka Verwendung von Cilastatin, Glutathione und N-acetyl-L-Cysteine zur Herstellung eines Arzneimittels zur Verbesserung der Resorption von Carbapenem oder Penem Antibiotika im Magen-Darm-Trakt
JP3132863B2 (ja) 1991-10-24 2001-02-05 富山化学工業株式会社 徐放性口腔用軟膏
US5654451B1 (en) * 1993-01-14 2000-02-22 Magainin Pharma Amino acids and peptides having modified c-terminals and modified n-terminals
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Also Published As

Publication number Publication date
CN1133428C (zh) 2004-01-07
EP0966974A4 (de) 2003-05-21
DE69922296T2 (de) 2005-10-27
US20020035160A1 (en) 2002-03-21
EP0966974A1 (de) 1999-12-29
US20020142040A1 (en) 2002-10-03
EP0966974B1 (de) 2004-12-01
CN1256633A (zh) 2000-06-14
WO1999036098A1 (fr) 1999-07-22
US20040151743A1 (en) 2004-08-05
DE69922296D1 (de) 2005-01-05
US6365635B1 (en) 2002-04-02
KR20000076105A (ko) 2000-12-26

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties