[go: up one dir, main page]

ATE280246T1 - Polymorphismuserkennung mit hilfe cluster-analyse - Google Patents

Polymorphismuserkennung mit hilfe cluster-analyse

Info

Publication number
ATE280246T1
ATE280246T1 AT98944444T AT98944444T ATE280246T1 AT E280246 T1 ATE280246 T1 AT E280246T1 AT 98944444 T AT98944444 T AT 98944444T AT 98944444 T AT98944444 T AT 98944444T AT E280246 T1 ATE280246 T1 AT E280246T1
Authority
AT
Austria
Prior art keywords
sample polymers
cluster analysis
polymorphism detection
differences
polymers
Prior art date
Application number
AT98944444T
Other languages
English (en)
Inventor
Anthony Berno
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Application granted granted Critical
Publication of ATE280246T1 publication Critical patent/ATE280246T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Holo Graphy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Control By Computers (AREA)
  • Image Analysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98944444T 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse ATE280246T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5593997P 1997-08-15 1997-08-15
PCT/US1998/016971 WO1999009218A1 (en) 1997-08-15 1998-08-14 Polymorphism detection utilizing clustering analysis

Publications (1)

Publication Number Publication Date
ATE280246T1 true ATE280246T1 (de) 2004-11-15

Family

ID=22001120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944444T ATE280246T1 (de) 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse

Country Status (8)

Country Link
US (3) US6223127B1 (de)
EP (1) EP1019536B1 (de)
JP (1) JP2001514907A (de)
AT (1) ATE280246T1 (de)
AU (1) AU9198298A (de)
CA (1) CA2299625A1 (de)
DE (1) DE69827154T2 (de)
WO (1) WO1999009218A1 (de)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US6223127B1 (en) * 1997-08-15 2001-04-24 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis
US6979728B2 (en) 1998-05-04 2005-12-27 Baylor College Of Medicine Articles of manufacture and methods for array based analysis of biological molecules
US6699659B2 (en) * 1998-06-01 2004-03-02 Affymetrix, Inc. Products and methods for analyzing nucleic acids including identification of substitutions, insertions and deletions
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US7179638B2 (en) 1999-07-30 2007-02-20 Large Scale Biology Corporation Microarrays and their manufacture by slicing
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
US20020052692A1 (en) * 1999-09-15 2002-05-02 Eoin D. Fahy Computer systems and methods for hierarchical cluster analysis of large sets of biological data including highly dense gene array data
WO2001029257A2 (en) * 1999-10-22 2001-04-26 Genset Methods of genetic cluster analysis
JP3563315B2 (ja) * 1999-12-14 2004-09-08 日立ソフトウエアエンジニアリング株式会社 樹状図表示方法及び樹状図表示システム
US20020067358A1 (en) * 2000-01-21 2002-06-06 Georg Casari Data analysis software
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
US20040101878A1 (en) * 2000-12-22 2004-05-27 Jones Michael H. High-throughput screening system by microarrays
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
AU2002320316A1 (en) * 2001-07-06 2003-01-21 Lipomics Technologies, Inc. Generating, viewing, interpreting, and utilizing a quantitative database of metabolites
US6799122B2 (en) * 2001-08-31 2004-09-28 Conagra Grocery Products Company Method for identifying polymorphic markers in a population
DK1438420T3 (da) * 2001-09-24 2010-01-18 Lipomics Technologies Inc Fremgangsmåder til anvendelse af kvantitative lipid-metablom-data
WO2003091426A1 (en) 2001-10-12 2003-11-06 Spectral Genomics, Inc. Compilations of nucleic acids and arrays and methods of using them
US7439346B2 (en) 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
EP1458486B1 (de) * 2001-12-19 2008-09-17 Affymetrix, Inc. Arrayplatten und verfahren zur herstellung von arrayplatten
US7272506B2 (en) * 2002-03-01 2007-09-18 Applera Corporation Computer algorithm for automatic allele determination from fluorometer genotyping device
AU2003228809A1 (en) 2002-05-03 2003-11-17 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
AU2003245269A1 (en) * 2002-05-03 2003-11-17 Vialogy Corporation System and method for characterizing microarray output data
US20050089909A1 (en) * 2002-05-31 2005-04-28 Mcgill University PTHrP-based prediction and diagnosis of bone disease
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
EP2316973A1 (de) 2003-06-10 2011-05-04 The Trustees Of Boston University Nachweismethoden für Lungenerkrankungen
US7259258B2 (en) 2003-12-17 2007-08-21 Illumina, Inc. Methods of attaching biological compounds to solid supports using triazine
US20050191682A1 (en) 2004-02-17 2005-09-01 Affymetrix, Inc. Methods for fragmenting DNA
US7035740B2 (en) * 2004-03-24 2006-04-25 Illumina, Inc. Artificial intelligence and global normalization methods for genotyping
US20050282174A1 (en) * 2004-06-19 2005-12-22 Webb Peter G Methods and systems for selecting nucleic acid probes for microarrays
WO2006022628A1 (en) * 2004-07-22 2006-03-02 Sequenom, Inc. Methods for identifying risk of type ii diabetes and treatments thereof
US8484000B2 (en) * 2004-09-02 2013-07-09 Vialogy Llc Detecting events of interest using quantum resonance interferometry
US20060073506A1 (en) 2004-09-17 2006-04-06 Affymetrix, Inc. Methods for identifying biological samples
EP1645640B1 (de) 2004-10-05 2013-08-21 Affymetrix, Inc. Verfahren zur Detektion von chromosomalen Translokationen
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
JP2006126204A (ja) 2004-10-29 2006-05-18 Affymetrix Inc ポリマーアレイを製造するための自動化方法
EP3211093A1 (de) 2005-04-14 2017-08-30 The Trustees of Boston University Diagnose für lungenerkrankungen mittels klassenvorhersage
US20070173139A1 (en) * 2006-01-24 2007-07-26 Charles Gierke Fishing assembly
CA2645310A1 (en) 2006-03-09 2007-09-13 The Trustees Of Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
EP2029777B1 (de) 2006-05-31 2017-03-08 Sequenom, Inc. Verfahren und zusammensetzungen zur nukleinsäureextraktion aus einer probe
EP2236623A1 (de) 2006-06-05 2010-10-06 Cancer Care Ontario Feststellung des Risikos für Kolorektalkrebs
JP5244103B2 (ja) 2006-08-09 2013-07-24 ホームステッド クリニカル コーポレイション 器官特異的蛋白質およびその使用方法
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
EP2450456A3 (de) 2006-11-02 2012-08-01 Yale University Beurteilung der Kompetenz von Eizellen
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
WO2008098014A2 (en) 2007-02-05 2008-08-14 Applied Biosystems, Llc System and methods for indel identification using short read sequencing
WO2008098142A2 (en) 2007-02-08 2008-08-14 Sequenom, Inc. Nucleic acid-based tests for rhd typing, gender determination and nucleic acid quantification
AU2008222563A1 (en) 2007-03-05 2008-09-12 Cancer Care Ontario Assessment of risk for colorectal cancer
WO2008118988A1 (en) 2007-03-26 2008-10-02 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
CA2710807C (en) 2008-03-11 2015-09-08 Kyeong Man Hong Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using snp array
CA2717320A1 (en) 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
CA2718137A1 (en) 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
EP3260123A1 (de) 2008-11-06 2017-12-27 University of Miami Rolle von löslichem upar in der pathogenese von proteinurischer nierenerkrankung
EP2382331B1 (de) 2009-01-07 2016-06-08 Myriad Genetics, Inc. Krebsbiomarker
IL289062B2 (en) 2009-02-11 2024-12-01 Caris Mpi Inc Molecular profiling of tumors
WO2010107946A2 (en) * 2009-03-18 2010-09-23 Sequenom, Inc. Use of thermostable endonucleases for generating reporter molecules
EP3211095B1 (de) 2009-04-03 2019-01-02 Sequenom, Inc. Zusammensetzungen und verfahren für die herstellung von nukleinsäuren
US20160186266A1 (en) 2009-10-27 2016-06-30 Carislife Sciences, Inc. Molecular profiling for personalized medicine
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
ES2577017T3 (es) 2009-12-22 2016-07-12 Sequenom, Inc. Procedimientos y kits para identificar la aneuploidia
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
WO2011091435A2 (en) 2010-01-25 2011-07-28 Mount Sinai School Of Medicine Methods of treating liver disease
AU2011248625B2 (en) 2010-04-26 2017-01-05 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
CN103096911B (zh) 2010-04-27 2018-05-29 Atyr 医药公司 与异亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2797271C (en) 2010-04-28 2021-05-25 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
WO2011150279A2 (en) 2010-05-27 2011-12-01 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases
US9034320B2 (en) 2010-04-29 2015-05-19 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Valyl-tRNA synthetases
US8986680B2 (en) 2010-04-29 2015-03-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
WO2011137368A2 (en) 2010-04-30 2011-11-03 Life Technologies Corporation Systems and methods for analyzing nucleic acid sequences
JP6008841B2 (ja) 2010-05-03 2016-10-19 エータイアー ファーマ， インコーポレイテッド メチオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
JP6008840B2 (ja) 2010-05-03 2016-10-19 エータイアー ファーマ， インコーポレイテッド フェニルアラニルαｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
JP5976638B2 (ja) 2010-05-03 2016-08-23 エータイアー ファーマ， インコーポレイテッド アルギニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
EP2566499B1 (de) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten aus einem p38-multi-trna-synthetase-komplex
EP2568996B1 (de) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Therapeutische, diagnostische und antikörperhaltige zusammensetzungen im zusammenhang mit proteinfragmenten von phenylalanyl-beta-trna-synthetasen
CN103118694B (zh) 2010-06-01 2016-08-03 Atyr医药公司 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
CA2804391A1 (en) 2010-07-07 2012-01-12 Myriad Genetics, Inc. Gene signatures for cancer prognosis
WO2012021247A2 (en) 2010-07-12 2012-02-16 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
AU2011293294B2 (en) 2010-08-25 2016-03-24 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases
AU2012249531B2 (en) 2011-04-29 2017-06-29 Sequenom, Inc. Quantification of a minority nucleic acid species
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
EP3311847A1 (de) 2012-02-16 2018-04-25 Atyr Pharma, Inc. Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen
US11177020B2 (en) 2012-02-27 2021-11-16 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
EP3321378B1 (de) 2012-02-27 2021-11-10 Becton, Dickinson and Company Zusammensetzungen für molekularen zählung
EP3401399B1 (de) 2012-03-02 2020-04-22 Sequenom, Inc. Verfahren und prozesse zur nicht-invasiven beurteilung genetischer variationen
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP2872648B1 (de) 2012-07-13 2019-09-04 Sequenom, Inc. Verfahren und zusammensetzungen zur methylierungsbasierten anreicherung fetaler nukleinsäure aus einer mütterlichen probe für nicht-invasive pränatale diagnosen
ES2938766T3 (es) 2012-11-16 2023-04-14 Myriad Genetics Inc Firmas génicas para el pronóstico de cáncer
US10260103B2 (en) 2012-11-27 2019-04-16 Pontificia Universidad Catolica De Chile Compositions and methods for diagnosing thyroid tumors
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
EP3597774A1 (de) 2013-03-13 2020-01-22 Sequenom, Inc. Primer zur analyse der dna-methylierung
WO2014151026A1 (en) 2013-03-15 2014-09-25 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
US10535420B2 (en) 2013-03-15 2020-01-14 Affymetrix, Inc. Systems and methods for probe design to detect the presence of simple and complex indels
US20140274749A1 (en) 2013-03-15 2014-09-18 Affymetrix, Inc. Systems and Methods for SNP Characterization and Identifying off Target Variants
CR20160132A (es) 2013-08-12 2016-08-25 Genentech Inc Composiciones y método para tratar condiciones asociadas con el complemento
TWI785472B (zh) 2014-02-08 2022-12-01 美商建南德克公司 治療阿茲海默症之方法
US11365447B2 (en) 2014-03-13 2022-06-21 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
UA123387C2 (uk) 2014-04-22 2021-03-31 Інвайролоджикс, Інк. Виділений праймерний олігонуклеотид та спосіб його застосування
EP3143160B1 (de) 2014-05-13 2019-11-06 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
CA2953016A1 (en) 2014-07-02 2016-01-07 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
EP3209802B1 (de) 2014-10-20 2022-09-07 Envirologix Inc. Zusammensetzungen und verfahren zum nachweis eines rna-virus
ES2993457T3 (en) 2015-01-30 2024-12-30 Envirologix Inc A substrate for a nicking and extension reaction comprising a nucleic acid duplex
CN108136051A (zh) 2015-08-04 2018-06-08 Cd诊断股份有限公司 检测不良局部组织反应(altr)坏死的方法
AU2016341845B2 (en) 2015-10-18 2022-11-17 Affymetrix, Inc. Multiallelic genotyping of single nucleotide polymorphisms and indels
CA3005119A1 (en) 2015-11-19 2017-05-26 Myriad Genetics, Inc. Signatures for predicting cancer immune therapy response
EP3400312A4 (de) 2016-01-06 2019-08-28 Myriad Genetics, Inc. Gene und gensignaturen zur diagnose und behandlung von melanomen
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
EP3645547A4 (de) 2017-06-26 2021-04-21 Phase Genomics Inc. Verfahren zum clustern von dna-sequenzen
TW201929907A (zh) 2017-12-22 2019-08-01 美商建南德克公司 Pilra結合劑用於治療疾病之用途
EP3807648A2 (de) 2018-06-18 2021-04-21 Igenomix S.L. Verfahren zur beurteilung der endometrialen transformation
EP3864165A4 (de) 2018-10-09 2022-08-03 Genecentric Therapeutics, Inc. Nachweis von ursprungskrebszellen
EP3888021B1 (de) 2018-11-30 2024-02-21 Caris MPI, Inc. Molekulare profilierung der nächsten generation
EP3956476A1 (de) 2019-04-17 2022-02-23 Igenomix S.L. Verbesserte verfahren zur frühdiagnose von uterinen leiomyomen und leiomyosarkomen
AU2020397802A1 (en) 2019-12-02 2022-06-16 Caris Mpi, Inc. Pan-cancer platinum response predictor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
JPH09507121A (ja) * 1993-10-26 1997-07-22 アフィマックス テクノロジーズ ナームロゼ ベノートスハップ 生物学的チップ上の核酸プローブアレー
WO1997027317A1 (en) 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
GB9521089D0 (en) * 1995-10-14 1995-12-20 Aromascan Plc Cluster analysis
WO1997029212A1 (en) * 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6223127B1 (en) * 1997-08-15 2001-04-24 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis

Also Published As

Publication number Publication date
US20040024537A1 (en) 2004-02-05
DE69827154T2 (de) 2006-03-09
US6584410B2 (en) 2003-06-24
EP1019536A4 (de) 2002-08-14
EP1019536A1 (de) 2000-07-19
US20010041965A1 (en) 2001-11-15
CA2299625A1 (en) 1999-02-25
DE69827154D1 (de) 2004-11-25
JP2001514907A (ja) 2001-09-18
AU9198298A (en) 1999-03-08
EP1019536B1 (de) 2004-10-20
US6223127B1 (en) 2001-04-24
WO1999009218A1 (en) 1999-02-25

Similar Documents

Publication Publication Date Title
ATE280246T1 (de) Polymorphismuserkennung mit hilfe cluster-analyse
Van Der Zee et al. Molecular genotyping of Staphylococcus aureus strains: comparison of repetitive element sequence-based PCR with various typing methods and isolation of a novel epidemicity marker
WO2001009381A3 (en) Methods of nucleic acid analysis by detecting molecular binding events
WO2003025540A3 (en) Differential tagging of polymers for high resolution linear analysis
WO2001059161A3 (en) Analyte assays employing universal arrays
BR0206318A (pt) Detecção de analitos
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
BR9908567A (pt) Processos de detecção de ácido nucléico zimogênico e moléculas relacionadas e kits
WO2005010494A3 (en) Multiplexed analyte detection
AU2001282920A1 (en) Methods for detecting and assaying nucleic acid sequences
WO2003102546A3 (en) Method and apparatus for detecting substances of interest
DE69637864D1 (de) Nachweis von amplifizierten nukleinsäuresequenzen durch bifunktionelle haptenisierung und farbige mikropartikel
DE60023539D1 (de) Immunologischer nachweis von rna:dna hybriden auf mikroarrays
CA2217074A1 (en) Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
GB8914563D0 (en) Detecting or quantifying multiple analytes using labelling techniques
WO2000034525A8 (en) Toxicity typing using embryoid bodies
ATE264923T1 (de) Verfahren und system zur erkennung von oligonukleotiden in einer probe
JP2005521411A5 (de)
EP0707075A3 (de) Spezies-spezifischer Nachweis von Mycobacterium Kansasii
EP1360329B8 (de) Biochemische methode und apparat zur detektion genetischer charakteristika
AUPR221400A0 (en) Diagnostic assay
ATE513058T1 (de) Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen
WO2001029262A3 (en) Genotyping reagents, kits and methods of use thereof
AU2002229974A1 (en) Biochemical method and apparatus for detecting protein characteristics

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties