ATE277943T1 - Trypsininhibitoren - Google Patents
TrypsininhibitorenInfo
- Publication number
- ATE277943T1 ATE277943T1 AT93905778T AT93905778T ATE277943T1 AT E277943 T1 ATE277943 T1 AT E277943T1 AT 93905778 T AT93905778 T AT 93905778T AT 93905778 T AT93905778 T AT 93905778T AT E277943 T1 ATE277943 T1 AT E277943T1
- Authority
- AT
- Austria
- Prior art keywords
- trypsin inhibitors
- trypsin
- compounds
- inhibitors
- novel
- Prior art date
Links
- 239000002753 trypsin inhibitor Substances 0.000 title 1
- 102000004142 Trypsin Human genes 0.000 abstract 2
- 108090000631 Trypsin Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012588 trypsin Substances 0.000 abstract 2
- 206010033645 Pancreatitis Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000451 tissue damage Effects 0.000 abstract 1
- 231100000827 tissue damage Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
- C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
- C07C281/10—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to an acyclic carbon atom or to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82838892A | 1992-01-30 | 1992-01-30 | |
| US08/011,666 US5534498A (en) | 1992-01-30 | 1993-01-29 | Trypsin inhibitors |
| PCT/US1993/000906 WO1993014779A1 (en) | 1992-01-30 | 1993-01-29 | Trypsin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE277943T1 true ATE277943T1 (de) | 2004-10-15 |
Family
ID=26682650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93905778T ATE277943T1 (de) | 1992-01-30 | 1993-01-29 | Trypsininhibitoren |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5714580A (de) |
| EP (1) | EP0627925B1 (de) |
| JP (1) | JPH07503715A (de) |
| AT (1) | ATE277943T1 (de) |
| CA (1) | CA2128711C (de) |
| DE (1) | DE69333639D1 (de) |
| WO (1) | WO1993014779A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5492895A (en) * | 1992-02-14 | 1996-02-20 | Corvas International, Inc. | Inhibitors of thrombosis |
| ATE171709T1 (de) * | 1992-02-14 | 1998-10-15 | Corvas Int Inc | Inhibitoren der thrombose |
| US5656600A (en) * | 1993-03-25 | 1997-08-12 | Corvas International, Inc. | α-ketoamide derivatives as inhibitors of thrombosis |
| US6211154B1 (en) * | 1995-06-07 | 2001-04-03 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US5856571A (en) * | 1995-06-07 | 1999-01-05 | Cellpro, Incorporated | Semicarbazide-containing linker compounds for formation of stably-linked conjugates and methods related thereto |
| US5919765A (en) * | 1995-06-07 | 1999-07-06 | Cor Therapeutics, Inc. | Inhibitors of factor XA |
| US6022861A (en) * | 1995-06-07 | 2000-02-08 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US6069130A (en) | 1995-06-07 | 2000-05-30 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US6046169A (en) * | 1995-06-07 | 2000-04-04 | Cor Therapeutics, Inc. | Inhibitors of factor XA |
| US5721214A (en) * | 1995-06-07 | 1998-02-24 | Cor Therapeutics, Inc. | Inhibitors of factor Xa |
| US6245743B1 (en) | 1996-06-05 | 2001-06-12 | Cor Therapeutics, Inc. | Inhibitors of factor Xa |
| US6087558A (en) * | 1998-07-22 | 2000-07-11 | Prodigene, Inc. | Commercial production of proteases in plants |
| US6787612B1 (en) | 1998-07-24 | 2004-09-07 | Dendreon Corporation | Resin derivatization method and uses thereof |
| BR9916733A (pt) * | 1999-01-02 | 2001-09-25 | Aventis Pharma Gmbh | Derivados de arilalcanoìla, processos para sua preparação, seu uso e composições farmacêuticas que os contêm |
| AU1624801A (en) | 1999-11-19 | 2001-05-30 | Corvas International, Inc. | Plasminogen activator inhibitor antagonists related applications |
| EP2295407B1 (de) * | 2000-03-22 | 2014-11-05 | Solulink, Inc. | Hydrazin- und Carbonyl-basierte bifunktionelle Vernetzungsmittel |
| US6872827B2 (en) | 2002-04-26 | 2005-03-29 | Chembridge Research Laboratories, Inc. | Somatostatin analogue compounds |
| WO2010132954A1 (en) * | 2009-05-21 | 2010-11-25 | Oral Health Australia Pty Ltd | Method of treating periodontal disease by administering antagonists of par-2 |
| MY162557A (en) | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2602443A1 (de) * | 1975-04-04 | 1976-10-21 | Univ California | Biologisch aktive polypeptide |
| US4171299A (en) * | 1975-04-04 | 1979-10-16 | The Regents Of The University Of California | Polypeptide agents for blocking the human allergic response |
| ATE171709T1 (de) * | 1992-02-14 | 1998-10-15 | Corvas Int Inc | Inhibitoren der thrombose |
-
1993
- 1993-01-29 EP EP93905778A patent/EP0627925B1/de not_active Expired - Lifetime
- 1993-01-29 WO PCT/US1993/000906 patent/WO1993014779A1/en active IP Right Grant
- 1993-01-29 CA CA002128711A patent/CA2128711C/en not_active Expired - Lifetime
- 1993-01-29 JP JP5513488A patent/JPH07503715A/ja active Pending
- 1993-01-29 DE DE69333639T patent/DE69333639D1/de not_active Expired - Lifetime
- 1993-01-29 AT AT93905778T patent/ATE277943T1/de not_active IP Right Cessation
-
1995
- 1995-05-31 US US08/455,974 patent/US5714580A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2128711A1 (en) | 1993-08-05 |
| WO1993014779A1 (en) | 1993-08-05 |
| EP0627925A4 (de) | 1997-07-30 |
| JPH07503715A (ja) | 1995-04-20 |
| EP0627925A1 (de) | 1994-12-14 |
| CA2128711C (en) | 2005-01-11 |
| EP0627925B1 (de) | 2004-09-29 |
| DE69333639D1 (en) | 2004-11-04 |
| US5714580A (en) | 1998-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |