ATE277939T1 - Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung - Google Patents
Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellungInfo
- Publication number
- ATE277939T1 ATE277939T1 AT00952136T AT00952136T ATE277939T1 AT E277939 T1 ATE277939 T1 AT E277939T1 AT 00952136 T AT00952136 T AT 00952136T AT 00952136 T AT00952136 T AT 00952136T AT E277939 T1 ATE277939 T1 AT E277939T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- ligands
- ligand
- aminopolycarboxylate
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 5
- 229910052723 transition metal Inorganic materials 0.000 title 1
- 150000003624 transition metals Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 2
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 2
- 239000003638 chemical reducing agent Substances 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- 230000000536 complexating effect Effects 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14098999P | 1999-06-29 | 1999-06-29 | |
| PCT/US2000/017813 WO2001000637A1 (en) | 1999-06-29 | 2000-06-28 | Group (vii) transition-metal complexes with multidentate aminopolycarboxylate ligands and a kit for producing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE277939T1 true ATE277939T1 (de) | 2004-10-15 |
Family
ID=22493669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00952136T ATE277939T1 (de) | 1999-06-29 | 2000-06-28 | Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1192166B1 (de) |
| JP (1) | JP2003503415A (de) |
| AT (1) | ATE277939T1 (de) |
| AU (1) | AU6488900A (de) |
| CA (1) | CA2377018A1 (de) |
| CZ (1) | CZ20014603A3 (de) |
| DE (1) | DE60014375T2 (de) |
| ES (1) | ES2223559T3 (de) |
| HU (1) | HUP0301779A3 (de) |
| WO (1) | WO2001000637A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6359119B1 (en) * | 2000-05-24 | 2002-03-19 | Mallinckrodt Inc. | Formulation of Tc and Re carbonyl complexes using stannous ion as the reductant for pertechnetate and perrhenate |
| US20060165594A1 (en) * | 2002-09-03 | 2006-07-27 | Roger Alberto | Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support |
| US7682601B2 (en) | 2003-04-15 | 2010-03-23 | Mallinckrodt Inc. | Bifunctional tridentate pyrazolyl containing ligands for re and tc tricarbonyl complexes |
| ATE470456T1 (de) | 2003-04-15 | 2010-06-15 | Mallinckrodt Inc | Bifunktionale tridentate pyrazolyl-enthaltende liganden für re-, tc- und mn- tricarbonyl- komplexe |
| AU2004235488A1 (en) | 2003-04-29 | 2004-11-11 | Universitat Zurich | Nepsilon and/or nalpha derivatized, metal and organic protected l-histidine for coupling to biomolecules for highly efficient labeling with [M(OH2)3(CO)3]+ by fac coordination |
| US8986650B2 (en) | 2005-10-07 | 2015-03-24 | Guerbet | Complex folate-NOTA-Ga68 |
| EP1940841B9 (de) | 2005-10-07 | 2017-04-19 | Guerbet | Verbindungen mit einem eine biologische zielstruktur erkennenden teil, das mit einem zum komplexieren von gallium fähigen signalteil gekoppelt ist |
| GB0623482D0 (en) | 2006-11-24 | 2007-01-03 | Mallinckrodt Inc | Technetium-99m (l) tricarbonyl complexes with tridentate chelators for myocardium imaging |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2113995C (en) * | 1991-08-29 | 2003-04-22 | Edward A. Deutsch | Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins |
| EP0879606A1 (de) * | 1997-04-25 | 1998-11-25 | Paul Scherrer Institut | Verfahren zur Herstellung von facial Metall Tricarbonyl Verbindungen und ihre Anwendung zur Markierung von Biosubstraten |
| DE19860289C2 (de) * | 1998-12-21 | 2003-11-13 | Schering Ag | Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium |
-
2000
- 2000-06-28 AT AT00952136T patent/ATE277939T1/de not_active IP Right Cessation
- 2000-06-28 HU HU0301779A patent/HUP0301779A3/hu unknown
- 2000-06-28 EP EP00952136A patent/EP1192166B1/de not_active Expired - Lifetime
- 2000-06-28 JP JP2001507045A patent/JP2003503415A/ja active Pending
- 2000-06-28 DE DE60014375T patent/DE60014375T2/de not_active Expired - Fee Related
- 2000-06-28 WO PCT/US2000/017813 patent/WO2001000637A1/en active IP Right Grant
- 2000-06-28 AU AU64889/00A patent/AU6488900A/en not_active Abandoned
- 2000-06-28 ES ES00952136T patent/ES2223559T3/es not_active Expired - Lifetime
- 2000-06-28 CA CA002377018A patent/CA2377018A1/en not_active Abandoned
- 2000-06-28 CZ CZ20014603A patent/CZ20014603A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2377018A1 (en) | 2001-01-04 |
| DE60014375T2 (de) | 2005-12-01 |
| EP1192166B1 (de) | 2004-09-29 |
| JP2003503415A (ja) | 2003-01-28 |
| DE60014375D1 (de) | 2004-11-04 |
| EP1192166A1 (de) | 2002-04-03 |
| WO2001000637A1 (en) | 2001-01-04 |
| AU6488900A (en) | 2001-01-31 |
| CZ20014603A3 (cs) | 2002-11-13 |
| ES2223559T3 (es) | 2005-03-01 |
| HUP0301779A3 (en) | 2008-01-28 |
| HUP0301779A2 (hu) | 2003-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Abrams et al. | Synthesis and characterization of hexakis (alkyl isocyanide) and hexakis (aryl isocyanide) complexes of technetium (I) | |
| Rapoport et al. | Cyclization via solid phase synthesis. Unidirectional Dieckmann products from solid phase and benzyl triethylcarbinyl pimelates | |
| Jurisson et al. | New oxotechnetium (V) complexes of N, N'-ethylenebis (acetylacetone imine), N, N'-ethylenebis (salicylideneamine), and o-phenylenebis (salicylideneamine). X-ray structures of the complexes of N, N'-ethylenebis (acetylacetone imine) and N, N'-ethylenebis (salicylideneamine) | |
| EP2922830B1 (de) | Synthese von imidazo(1,2-a)pyrazin-4-ium-salzen zur synthese von 1,4,7-triazacyclononan (tacn) und n- und/oder c-funktionalisierten derivaten davon | |
| Ihrig et al. | Carbon magnetic resonance studies of enriched compounds. Carbon-13-carbon-13 coupling constants of 13C-7 labeled monosubstituted benzene derivatives | |
| Boatman et al. | An anionic equivalent of the Friedel-Crafts cycloacylation | |
| ATE277939T1 (de) | Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung | |
| Kane-Maguire et al. | Unusual photobehavior of trans-dicyano (1, 4, 8, 11-tetraazacyclotetradecane) chromium (III) perchlorate | |
| Thomas et al. | Technetium radiopharmaceutical development. 2. Preparation, characterization, and synthetic utility of the oxotetrahalotechnetate (V) species TcOX4-(X= chloro, bromo, iodo) | |
| Jarrett et al. | Nickel (II) bis (phosphine) complexes | |
| Baumann et al. | Reactions of coordinated dinitrogen. 18. Formation of ammonia and hydrazine from the reactions of acids with bis (dinitrogen) complexes of molybdenum. Identification and isolation of intermediates. Possible analogy with the hydrazine-forming property of nitrogenase | |
| Murase et al. | Synthesis and characterization of copper (II), nickel (II), and cobalt (II) binuclear complexes with a new tricyclic octadentate ligand, 1, 5, 8, 12, 15, 19, 22, 26-octaazatricyclo [17.9. 2.25, 15] dotriacontane (tcoa): trapping of carbon dioxide in a neutral aqueous solution | |
| Balch et al. | Reactions involving chelate ring opening or metal ion relocation in the formation of luminescent complexes containing both gold and iridium | |
| Komiya et al. | Isolation of a zerovalent iron dinitrogen complex with 1, 2-bis (diethylphosphino) ethane ligands | |
| CA2039732A1 (en) | Cores for technetium radiopharmaceuticals | |
| WO2001089586A3 (en) | Tc and re carbonyl complexes for pertechnetate and perrhenate | |
| Clarke et al. | The chemistry of technetium: Toward improved diagnostic agents | |
| Lapouyade et al. | Primary and tertiary amines as catalysts of hydrogen transfer in the photocyclization of 1, 1-diarylethylenes | |
| Luneva et al. | A Novel Mixed‐Valence Tetranuclear Vii/Viii Complex Isolated from 3, 5‐Di‐tert‐Butylcatechol/Vanadium (ii)/Sodium Methoxide System for Dinitrogen Reduction | |
| US5589576A (en) | Cores for technetium radiopharmaceuticals | |
| Murakami et al. | Transition-metal Complexes of Pyrrole Pigments. IX. Divalent and Trivalent Iron Chelates of Dipyrromethenes | |
| Kanemasa et al. | Temperature dependent 1H NMR study of the substrate complex derived from zinc (II) perchlorate,(R, R)-4, 6-dibenzofurandiyl-2, 2′-bis (4-phenyloxazoline), and 3-acetyl-2-oxazolidinone. Evidence for octahedral structure of the substrate complex | |
| Mach et al. | Synthesis, characterization and biodistribution of neutral and lipid-soluble 99mTc-PAT-HM and 99mTc-TMR for brain imaging | |
| CA2043368A1 (en) | Tetranuclear manganese complexes | |
| Paul et al. | Iron (III) acetates |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1192166 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |