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ATE277170T1 - Stereoselektive transaminase, deren kodierende gen und deren verwendungen - Google Patents

Stereoselektive transaminase, deren kodierende gen und deren verwendungen

Info

Publication number
ATE277170T1
ATE277170T1 AT00400701T AT00400701T ATE277170T1 AT E277170 T1 ATE277170 T1 AT E277170T1 AT 00400701 T AT00400701 T AT 00400701T AT 00400701 T AT00400701 T AT 00400701T AT E277170 T1 ATE277170 T1 AT E277170T1
Authority
AT
Austria
Prior art keywords
gene coding
stereoselective transaminase
stereoselective
transaminase
protein
Prior art date
Application number
AT00400701T
Other languages
English (en)
Inventor
Yoshiki Takashima
Satoshi Mitsuda
Marco Wieser
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Application granted granted Critical
Publication of ATE277170T1 publication Critical patent/ATE277170T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00400701T 1999-03-19 2000-03-14 Stereoselektive transaminase, deren kodierende gen und deren verwendungen ATE277170T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7551199 1999-03-19
JP8863499 1999-03-30

Publications (1)

Publication Number Publication Date
ATE277170T1 true ATE277170T1 (de) 2004-10-15

Family

ID=26416636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00400701T ATE277170T1 (de) 1999-03-19 2000-03-14 Stereoselektive transaminase, deren kodierende gen und deren verwendungen

Country Status (4)

Country Link
US (2) US6413752B1 (de)
EP (1) EP1038953B1 (de)
AT (1) ATE277170T1 (de)
DE (1) DE60013939T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7202070B2 (en) * 2000-10-31 2007-04-10 Biocatalytics, Inc. Method for reductive amination of a ketone using a mutated enzyme
US20050009151A1 (en) * 2003-07-10 2005-01-13 Pharmacia Corporation Methods for the stereospecific and enantiomeric enrichment of beta-amino acids
DE202004014986U1 (de) * 2004-09-25 2006-02-02 A & M Electric Tools Gmbh Umlaufrädergetriebe
US7172885B2 (en) * 2004-12-10 2007-02-06 Cambrex North Brunswick, Inc. Thermostable omega-transaminases
US8586398B2 (en) * 2008-01-18 2013-11-19 Miasole Sodium-incorporation in solar cell substrates and contacts
DK2385983T3 (en) 2009-01-08 2018-02-12 Codexis Inc Transaminase POLYPEPTIDES
EP2401366B1 (de) * 2009-02-26 2013-12-18 Codexis, Inc. Transaminase-biokatalysatoren
WO2011005477A1 (en) * 2009-06-22 2011-01-13 Codexis, Inc. Transaminase reactions
CA2772426A1 (en) 2009-09-02 2011-03-10 Lonza Ag A process for the identification and preparation of a (r)-specific omega-transaminase
US8852900B2 (en) 2010-06-17 2014-10-07 Codexis, Inc. Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol
WO2012007548A1 (en) 2010-07-14 2012-01-19 Dsm Ip Assets B.V. (r)-selective amination
WO2014037376A1 (en) 2012-09-04 2014-03-13 C5 Ligno Technologies In Lund Ab Stereoselective biosynthesis in microbial host cells
CN109234327A (zh) * 2017-07-11 2019-01-18 上海弈柯莱生物医药科技有限公司 一种立体选择性的转氨酶在不对称合成手性胺中的应用
WO2021077425A1 (zh) * 2019-10-25 2021-04-29 凯莱英医药化学（阜新）技术有限公司 转氨酶突变体及其应用
CN113881720B (zh) * 2020-12-31 2023-08-25 上海合全药物研发有限公司 一种转氨酶及使用其进行催化制备的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522630A (en) * 1978-08-07 1980-02-18 Mitsui Toatsu Chem Inc Preparation of alpha-phenylethylamine
JPS60248647A (ja) * 1984-05-25 1985-12-09 Yamakawa Yakuhin Kogyo Kk α−フエニルエチルアミンの製造法
JPS61187786A (ja) 1985-02-14 1986-08-21 Daicel Chem Ind Ltd 耐熱性ｄ−アミノ酸トランスアミナ−ゼ
US4950606A (en) * 1989-06-22 1990-08-21 Celgene Corporation Enantiomeric enrichment and stereoselective synthesis of chiral amines
DE69635082T2 (de) 1995-10-23 2006-06-01 Kaneka Corp. Verfahren zur herstellung optisch aktiver aminoverbindungen
JPH10165194A (ja) 1996-12-12 1998-06-23 Sumitomo Chem Co Ltd 光学純度の向上方法
DE69841075D1 (de) 1997-04-23 2009-10-01 Kaneka Corp Deoxynukleinsäure welche ein Polypeptid mit stereoselektiver Transaminase Aktivität kodiert, sowie die Deoxynukleinsäure enthaltende Transformanden
CZ295882B6 (cs) * 1998-03-11 2005-11-16 Celgro Způsob zlepšení enzymatické syntézy chirálních aminů
WO2000026351A1 (fr) * 1998-10-30 2000-05-11 Kaneka Corporation (S)-α-PHENETHYLAMINE : TRANSAMINASE DE PYRUVATE

Also Published As

Publication number Publication date
US20020127664A1 (en) 2002-09-12
DE60013939D1 (de) 2004-10-28
US6727083B2 (en) 2004-04-27
EP1038953B1 (de) 2004-09-22
DE60013939T2 (de) 2005-10-06
EP1038953A1 (de) 2000-09-27
US6413752B1 (en) 2002-07-02

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