ATE274498T1 - Verfahren zur herstellung von benzocycloheptapyridin-11-one - Google Patents
Verfahren zur herstellung von benzocycloheptapyridin-11-oneInfo
- Publication number
- ATE274498T1 ATE274498T1 AT99926713T AT99926713T ATE274498T1 AT E274498 T1 ATE274498 T1 AT E274498T1 AT 99926713 T AT99926713 T AT 99926713T AT 99926713 T AT99926713 T AT 99926713T AT E274498 T1 ATE274498 T1 AT E274498T1
- Authority
- AT
- Austria
- Prior art keywords
- benzocycloheptapyridine
- producing
- substituents
- formula
- scheme
- Prior art date
Links
- XSJUXLNYEPQDRF-UHFFFAOYSA-N cyclohepta[f]quinolin-11-one Chemical compound O=C1C=CC=CC2=CC=C(N=CC=C3)C3=C12 XSJUXLNYEPQDRF-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- LMHIBYREWJHKNZ-UHFFFAOYSA-N 3-methylpyridine-2-carboxylic acid Chemical class CC1=CC=CN=C1C(O)=O LMHIBYREWJHKNZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910001413 alkali metal ion Inorganic materials 0.000 abstract 1
- -1 alkali metal salts Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 229910003002 lithium salt Inorganic materials 0.000 abstract 1
- 159000000002 lithium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE980619 | 1998-07-24 | ||
| IE980776 | 1998-09-18 | ||
| PCT/IE1999/000054 WO2000005215A1 (en) | 1998-07-24 | 1999-06-18 | A process for preparing benzocycloheptapyridin-11-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274498T1 true ATE274498T1 (de) | 2004-09-15 |
Family
ID=26320210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926713T ATE274498T1 (de) | 1998-07-24 | 1999-06-18 | Verfahren zur herstellung von benzocycloheptapyridin-11-one |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1098882B1 (de) |
| AT (1) | ATE274498T1 (de) |
| AU (1) | AU4387699A (de) |
| DE (1) | DE69919720D1 (de) |
| WO (1) | WO2000005215A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004501081A (ja) | 2000-04-18 | 2004-01-15 | シェーリング コーポレイション | 三環式化合物の調製において有用な中間体の合成 |
| MXPA03002448A (es) | 2000-09-20 | 2003-06-19 | Schering Corp | Eimidazoles sustituidos como agonistas o antagonistas duales h1 y h3 de histamina. |
| EP1421068B1 (de) * | 2001-08-21 | 2008-07-09 | Schering Corporation | Verfahren zur herstellung von einem trizyklischen keton zwischenprodukt |
| ITMI20012308A1 (it) * | 2001-11-05 | 2003-05-05 | Zambon Spa | Processo per la preparazione dell'estere etilico dell'acido 4-(8-cloro-5,6-diidro-11h-benzo-5,67-cicloepta-1,2-b-piridin-11-ilidene)-1-piper |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL132137C (de) * | 1963-04-24 | |||
| DE3677842D1 (de) * | 1985-05-13 | 1991-04-11 | Schering Corp | Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln. |
| US4804666A (en) * | 1985-08-14 | 1989-02-14 | Schering Corporation | Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines |
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| JP2001521489A (ja) * | 1996-09-13 | 2001-11-06 | シェーリング コーポレイション | ファルネシルタンパク質トランスフェラーゼインヒビターである三環式抗腫瘍性化合物 |
| CH688412A5 (de) * | 1997-03-11 | 1997-09-15 | Cilag Ag | Verfahren zur Herstellung von 1,4-disubstituierten Piperidinverbindungen. |
-
1999
- 1999-06-18 AU AU43876/99A patent/AU4387699A/en not_active Abandoned
- 1999-06-18 AT AT99926713T patent/ATE274498T1/de not_active IP Right Cessation
- 1999-06-18 DE DE69919720T patent/DE69919720D1/de not_active Expired - Lifetime
- 1999-06-18 EP EP99926713A patent/EP1098882B1/de not_active Expired - Lifetime
- 1999-06-18 WO PCT/IE1999/000054 patent/WO2000005215A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1098882B1 (de) | 2004-08-25 |
| AU4387699A (en) | 2000-02-14 |
| DE69919720D1 (de) | 2004-09-30 |
| WO2000005215A1 (en) | 2000-02-03 |
| EP1098882A1 (de) | 2001-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |