ATE268590T1 - Pharmazeutische emulsion enthaltend sorbinsäure, na-edta und borsäure - Google Patents
Pharmazeutische emulsion enthaltend sorbinsäure, na-edta und borsäureInfo
- Publication number
- ATE268590T1 ATE268590T1 AT98103247T AT98103247T ATE268590T1 AT E268590 T1 ATE268590 T1 AT E268590T1 AT 98103247 T AT98103247 T AT 98103247T AT 98103247 T AT98103247 T AT 98103247T AT E268590 T1 ATE268590 T1 AT E268590T1
- Authority
- AT
- Austria
- Prior art keywords
- emulsion
- pharmaceutically acceptable
- boric acid
- acid
- sorbic acid
- Prior art date
Links
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 title abstract 6
- 239000004327 boric acid Substances 0.000 title abstract 6
- 239000004334 sorbic acid Substances 0.000 title abstract 6
- 229940075582 sorbic acid Drugs 0.000 title abstract 6
- 235000010199 sorbic acid Nutrition 0.000 title abstract 6
- WSWCOQWTEOXDQX-MQQKCMAXSA-N E-Sorbic acid Chemical compound C\C=C\C=C\C(O)=O WSWCOQWTEOXDQX-MQQKCMAXSA-N 0.000 title 1
- 239000008251 pharmaceutical emulsion Substances 0.000 title 1
- 239000000839 emulsion Substances 0.000 abstract 12
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 abstract 5
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 5
- 229940037001 sodium edetate Drugs 0.000 abstract 5
- 238000004321 preservation Methods 0.000 abstract 4
- 239000003755 preservative agent Substances 0.000 abstract 4
- 230000002335 preservative effect Effects 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4654897 | 1997-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268590T1 true ATE268590T1 (de) | 2004-06-15 |
Family
ID=12750377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98103247T ATE268590T1 (de) | 1997-02-28 | 1998-02-25 | Pharmazeutische emulsion enthaltend sorbinsäure, na-edta und borsäure |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6379688B2 (de) |
| EP (1) | EP0861658B1 (de) |
| KR (1) | KR19980071702A (de) |
| AT (1) | ATE268590T1 (de) |
| CA (1) | CA2230805A1 (de) |
| DE (1) | DE69824326T2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872705B2 (en) * | 2001-07-13 | 2005-03-29 | Allergan, Inc. | Use of antimicrobial peptides as preservatives in ophthalmic preparations, including solutions, emulsions, and suspensions |
| DE102004045622A1 (de) * | 2004-09-17 | 2006-03-30 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Konservierungsmittel-Zusammensetzungen |
| US8147815B2 (en) * | 2005-12-16 | 2012-04-03 | Celmatrix Corporation | Topical administration carrier composition and therapeutic formulations comprising same |
| US20090074881A1 (en) * | 2006-05-02 | 2009-03-19 | Bioneutral Laboratories Corporation Usa | Antimicrobial cidality formulations with residual efficacy, uses thereof, and the preparation thereof |
| CN101500541B (zh) * | 2006-08-11 | 2011-06-15 | 旭化成化学株式会社 | 含有水难溶性药物的球状素颗粒的制造方法 |
| CN101674807B (zh) | 2007-05-04 | 2013-03-20 | 博士伦公司 | 用于缓解、改善、治疗或预防干眼症的组合物及其制备和使用方法 |
| CN102370617B (zh) * | 2010-08-13 | 2013-09-11 | 中国科学院上海药物研究所 | 石杉碱甲眼用微乳制剂及其制备方法 |
| EP2630952A1 (de) * | 2012-02-23 | 2013-08-28 | Novagali Pharma S.A. | Selbstkonservierende Öldispersionen enthaltend Borsäure |
| RU2675813C2 (ru) * | 2013-02-15 | 2018-12-25 | Сэндзю Фармацевтикал Ко., Лтд. | Эмульсионная композиция дифлупредната, содержащая цинк |
| WO2016127022A1 (en) | 2015-02-06 | 2016-08-11 | Foreman James Michael | Preparation of an oil-in-water emulsion for polymer stabilized pharmaceutical formulations |
| US9962444B2 (en) | 2016-09-27 | 2018-05-08 | Shane Malek | Pharmacokinetically extended action topical hair growth formulation, and administration method |
| FR3104961B1 (fr) * | 2019-12-20 | 2022-03-25 | Oreal | Composition cosmetique comprenant au moins un polyol comportant au moins trois fonctions hydroxy et au moins un ester de sorbitan polyoxyethylene |
| GB202013645D0 (en) * | 2020-08-31 | 2020-10-14 | Innotesto Bvba | Pharmacetical compositions for the nasal administration of a colbalamin compound |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3911107A (en) | 1972-12-18 | 1975-10-07 | Flow Pharma Inc | Iodine composition and dissipating solution |
| US4031209A (en) | 1972-12-18 | 1977-06-21 | Flow Pharmaceuticals, Inc. | Aqueous solution suitable for dissipating available iodine contained in an iodophor |
| US3906108A (en) * | 1973-10-12 | 1975-09-16 | Johnson & Johnson | Stabilized tretinoin cream emulsion |
| DE2537303C3 (de) * | 1975-06-02 | 1980-03-13 | Flow Pharmaceuticals, Inc., Palo Alto, Calif. (V.St.A.) | Sterile wäßrige Lösung für die Abgabe oder Verteilung von verfügbarem Jod und deren Verwendung |
| US4188373A (en) | 1976-02-26 | 1980-02-12 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
| JPH0737381B2 (ja) * | 1987-05-15 | 1995-04-26 | 参天製薬株式会社 | ビタミンｅ水性製剤 |
| DE3917109A1 (de) * | 1989-05-26 | 1990-12-06 | Anasco Gmbh | Mittel zur bekaempfung des schnarchens |
| JP3090353B2 (ja) | 1991-09-17 | 2000-09-18 | 旭化成工業株式会社 | パラチロイドホルモン類含有経鼻投与用乳剤 |
| EP0642789B1 (de) | 1992-05-22 | 1999-09-29 | Senju Pharmaceutical Co., Ltd. | Arzneimittel gegen glaukom |
| JP2811036B2 (ja) | 1992-05-26 | 1998-10-15 | 参天製薬株式会社 | ビタミンｅ点眼剤 |
| JP3662944B2 (ja) * | 1993-08-24 | 2005-06-22 | 協和醗酵工業株式会社 | 点鼻剤 |
| JPH08133967A (ja) * | 1994-11-02 | 1996-05-28 | Eisai Co Ltd | ドライアイ治療剤 |
| JPH08193024A (ja) * | 1995-01-17 | 1996-07-30 | Ikeda Mohandou:Kk | 点眼剤組成物 |
-
1998
- 1998-02-24 US US09/028,311 patent/US6379688B2/en not_active Expired - Lifetime
- 1998-02-25 KR KR1019980005943A patent/KR19980071702A/ko not_active Application Discontinuation
- 1998-02-25 DE DE69824326T patent/DE69824326T2/de not_active Expired - Lifetime
- 1998-02-25 AT AT98103247T patent/ATE268590T1/de not_active IP Right Cessation
- 1998-02-25 EP EP98103247A patent/EP0861658B1/de not_active Expired - Lifetime
- 1998-02-27 CA CA002230805A patent/CA2230805A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0861658A1 (de) | 1998-09-02 |
| DE69824326T2 (de) | 2005-06-16 |
| EP0861658B1 (de) | 2004-06-09 |
| US6379688B2 (en) | 2002-04-30 |
| CA2230805A1 (en) | 1998-08-28 |
| DE69824326D1 (de) | 2004-07-15 |
| US20010003003A1 (en) | 2001-06-07 |
| KR19980071702A (ko) | 1998-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |