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ATE268377T1 - Ex-vivo unter oxidativen stress behandelte cll- zellen zur behandlung chronischer lymphozytärer läukemie (cll) - Google Patents

Ex-vivo unter oxidativen stress behandelte cll- zellen zur behandlung chronischer lymphozytärer läukemie (cll)

Info

Publication number
ATE268377T1
ATE268377T1 AT01981999T AT01981999T ATE268377T1 AT E268377 T1 ATE268377 T1 AT E268377T1 AT 01981999 T AT01981999 T AT 01981999T AT 01981999 T AT01981999 T AT 01981999T AT E268377 T1 ATE268377 T1 AT E268377T1
Authority
AT
Austria
Prior art keywords
cll
lymphocytic leukemia
chronic lymphocytic
treatment
oxidative stress
Prior art date
Application number
AT01981999T
Other languages
English (en)
Inventor
David Elliott Spaner
Original Assignee
Vasogen Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vasogen Ireland Ltd filed Critical Vasogen Ireland Ltd
Application granted granted Critical
Publication of ATE268377T1 publication Critical patent/ATE268377T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/40Peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0023Agression treatment or altering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • C12N5/0694Cells of blood, e.g. leukemia cells, myeloma cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT01981999T 2000-10-25 2001-10-25 Ex-vivo unter oxidativen stress behandelte cll- zellen zur behandlung chronischer lymphozytärer läukemie (cll) ATE268377T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA 2324199 CA2324199A1 (en) 2000-10-25 2000-10-25 Chronic lymphocytic leukemia treatment
PCT/CA2001/001497 WO2002034888A1 (en) 2000-10-25 2001-10-25 Ex vivo oxidatively stressed cll cells in chronic lymphocytic leukemia (cll) treatment

Publications (1)

Publication Number Publication Date
ATE268377T1 true ATE268377T1 (de) 2004-06-15

Family

ID=4167457

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01981999T ATE268377T1 (de) 2000-10-25 2001-10-25 Ex-vivo unter oxidativen stress behandelte cll- zellen zur behandlung chronischer lymphozytärer läukemie (cll)

Country Status (8)

Country Link
US (1) US6733748B2 (de)
EP (1) EP1330514B1 (de)
AT (1) ATE268377T1 (de)
AU (1) AU2002213700A1 (de)
CA (1) CA2324199A1 (de)
DE (1) DE60103658D1 (de)
NZ (1) NZ525275A (de)
WO (1) WO2002034888A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050063995A1 (en) * 2001-10-25 2005-03-24 Spaner David E Compositions and methods for selected tumour treatment
CA2377442A1 (en) * 2002-03-20 2003-09-20 Thomas Ichim Increasing tumor oxygen content by administration of stressed cells
AU2003266086A1 (en) * 2002-09-16 2004-04-30 Vasogen Ireland Limited Chronic lymphocytic leukemia combination treatment (treated cll cells and cytokine)
US20060189543A1 (en) * 2005-02-23 2006-08-24 Rosenbloom Richard A Compositions and methods for the treatment of leukemia
WO2010033771A2 (en) * 2008-09-19 2010-03-25 Trustees Of The University Of Pennsylvania Modulators of hsp70/dnak function and methods of use thereof
US9943607B2 (en) 2011-05-09 2018-04-17 Biothera, Inc. Beta-glucan compounds, compositions, and methods
US10010560B2 (en) 2014-02-26 2018-07-03 The Trustees Of The University Of Pennsylvania Small molecule HSP70 inhibitors
US20210000936A1 (en) * 2018-03-21 2021-01-07 Colorado State University Research Foundation Cancer vaccine compositions and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980954A (en) * 1992-02-07 1999-11-09 Vasogen Ireland Limited Treatment of autoimmune diseases
US6649364B1 (en) 1995-06-07 2003-11-18 The Regents Of The University Of California Anti-apoptotic compositions and methods using same
EP1028754B1 (de) 1997-11-12 2008-08-27 The Trustees Of The University Of Pennsylvania Verhinderung von immunreaktivität durch verarmung oder inhibition von antigen-präsentierenden zellen
CA2244554A1 (en) 1998-07-30 2000-01-30 Vasogen Inc. Inhibition of graft versus host disease
WO2000041705A1 (en) 1999-01-12 2000-07-20 Vasogen Ireland Limited Pre-conditioning against cell death
CA2297448A1 (en) 2000-01-28 2001-07-28 Vasogen Inc. Improved inhibition of graft versus host disease

Also Published As

Publication number Publication date
EP1330514A1 (de) 2003-07-30
US6733748B2 (en) 2004-05-11
EP1330514B1 (de) 2004-06-02
DE60103658D1 (de) 2004-07-08
NZ525275A (en) 2004-08-27
CA2324199A1 (en) 2002-04-25
US20020090358A1 (en) 2002-07-11
WO2002034888A1 (en) 2002-05-02
AU2002213700A1 (en) 2002-05-06

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