ATE264843T1 - Antibakterielle mutiline - Google Patents
Antibakterielle mutilineInfo
- Publication number
- ATE264843T1 ATE264843T1 AT01972046T AT01972046T ATE264843T1 AT E264843 T1 ATE264843 T1 AT E264843T1 AT 01972046 T AT01972046 T AT 01972046T AT 01972046 T AT01972046 T AT 01972046T AT E264843 T1 ATE264843 T1 AT E264843T1
- Authority
- AT
- Austria
- Prior art keywords
- mutiline
- antibacterial
- antibacterial mutiline
- Prior art date
Links
- OBUUFWIMEGVAQS-KWMSOUESSA-N (1S,2R,3S,4S,6R,7R,8S,14R)-4-ethenyl-3,6-dihydroxy-2,4,7,14-tetramethyltricyclo[5.4.3.01,8]tetradecan-9-one Chemical compound C([C@H]([C@@]1(C)[C@H](O)C[C@@](C)(C=C)[C@@H](O)[C@@H]2C)C)C[C@]32[C@@H]1C(=O)CC3 OBUUFWIMEGVAQS-KWMSOUESSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0022439A GB0022439D0 (en) | 2000-09-13 | 2000-09-13 | Organic compounds |
| GB0022440A GB0022440D0 (en) | 2000-09-13 | 2000-09-13 | Organic Compounds |
| GB0024674A GB0024674D0 (en) | 2000-10-09 | 2000-10-09 | Organic compounds |
| PCT/EP2001/010502 WO2002022580A1 (en) | 2000-09-13 | 2001-09-11 | Antibacterials mutilins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264843T1 true ATE264843T1 (de) | 2004-05-15 |
Family
ID=27255885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01972046T ATE264843T1 (de) | 2000-09-13 | 2001-09-11 | Antibakterielle mutiline |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US7169804B2 (de) |
| EP (1) | EP1320525B1 (de) |
| JP (1) | JP5134181B2 (de) |
| CN (1) | CN1288134C (de) |
| AR (1) | AR030651A1 (de) |
| AT (1) | ATE264843T1 (de) |
| AU (1) | AU2001291854A1 (de) |
| BR (1) | BRPI0113837B8 (de) |
| CA (1) | CA2418538C (de) |
| DE (1) | DE60102936T2 (de) |
| ES (1) | ES2220809T3 (de) |
| MY (1) | MY133930A (de) |
| PE (1) | PE20020676A1 (de) |
| PT (1) | PT1320525E (de) |
| TW (1) | TWI306852B (de) |
| WO (1) | WO2002022580A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9918037D0 (en) * | 1999-07-30 | 1999-09-29 | Biochemie Gmbh | Organic compounds |
| GB0207495D0 (en) | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
| GB0209262D0 (en) * | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
| BRPI0312882B8 (pt) | 2002-07-24 | 2021-05-25 | Nabriva Therapeutics Ag | derivados de pleuromutilina e composição farmacêutica |
| GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
| US7544963B2 (en) * | 2005-04-29 | 2009-06-09 | Cree, Inc. | Binary group III-nitride based high electron mobility transistors |
| GB0513058D0 (en) * | 2005-06-27 | 2005-08-03 | Sandoz Ag | Organic compounds |
| WO2007037518A1 (ja) * | 2005-09-29 | 2007-04-05 | Dainippon Sumitomo Pharma Co., Ltd. | ムチリン誘導体及びそれを含有する医薬組成物 |
| EP1808431A1 (de) * | 2006-01-16 | 2007-07-18 | Nabriva Therapeutics Forschungs GmbH | Mutilin Derivate und ihre Verwendung als Arzneimittel |
| CA2654450A1 (en) * | 2006-06-05 | 2007-12-13 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted erythromycin analogs |
| EP1908750A1 (de) * | 2006-10-05 | 2008-04-09 | Nabriva Therapeutics Forschungs GmbH | Verfahren zur Herstellung von Pleuromutilinen |
| CA2688008A1 (en) | 2007-05-24 | 2008-11-27 | Kyorin Pharmaceutical Co., Ltd. | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| WO2010056855A1 (en) * | 2008-11-13 | 2010-05-20 | Teva Pharmaceutical Industries Ltd. | Preparation of retapamulin via its pleuromutilin-thiol precursor |
| CN103709115A (zh) * | 2012-10-09 | 2014-04-09 | 山东亨利医药科技有限责任公司 | 截短侧耳素类抗生素衍生物 |
| TWI762573B (zh) | 2017-02-10 | 2022-05-01 | 奧地利商納畢瓦治療有限責任公司 | 截短側耳素之純化 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE789629A (fr) * | 1971-10-05 | 1973-04-03 | Sandoz Sa | Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique |
| DE2811314A1 (de) * | 1978-03-16 | 1979-09-27 | Sandoz Ag | Kokzidiostatisches kombinationspraeparat |
| JPS5594359A (en) * | 1979-01-12 | 1980-07-17 | Sandoz Ag | Novel pleuromutilin derivatives*their manufacture and use |
| EP0013768B1 (de) | 1979-01-12 | 1984-02-01 | Sandoz Ag | Pleuromutilin-Derivate, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| DE3560511D1 (en) * | 1984-02-17 | 1987-10-01 | Sandoz Ag | Pleuromutilin derivatives, process for their preparation and their use |
| JP3054875B2 (ja) * | 1995-02-13 | 2000-06-19 | 株式会社小松製作所 | プラズマトーチ |
| ES2205072T3 (es) * | 1996-01-03 | 2004-05-01 | Smithkline Beecham Plc | Derivados carbamoiloxi de mutilina y su uso como agentes antibacterianos. |
| UY25225A1 (es) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
| WO2000027790A1 (en) * | 1998-11-11 | 2000-05-18 | Smithkline Beecham P.L.C. | Mutilin compounds |
| AU3036200A (en) | 1998-12-18 | 2000-07-12 | Smithkline Beecham Plc | Mutilin 14-ester derivatives having antibacterial activity |
| GB9918037D0 (en) * | 1999-07-30 | 1999-09-29 | Biochemie Gmbh | Organic compounds |
| GB0207495D0 (en) * | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
| BRPI0312882B8 (pt) * | 2002-07-24 | 2021-05-25 | Nabriva Therapeutics Ag | derivados de pleuromutilina e composição farmacêutica |
-
2001
- 2001-09-10 PE PE2001000905A patent/PE20020676A1/es not_active Application Discontinuation
- 2001-09-11 JP JP2002526833A patent/JP5134181B2/ja not_active Expired - Lifetime
- 2001-09-11 AR ARP010104289A patent/AR030651A1/es not_active Application Discontinuation
- 2001-09-11 MY MYPI20014254 patent/MY133930A/en unknown
- 2001-09-11 PT PT01972046T patent/PT1320525E/pt unknown
- 2001-09-11 CN CNB018155766A patent/CN1288134C/zh not_active Expired - Lifetime
- 2001-09-11 EP EP01972046A patent/EP1320525B1/de not_active Expired - Lifetime
- 2001-09-11 BR BRPI0113837 patent/BRPI0113837B8/pt not_active IP Right Cessation
- 2001-09-11 AU AU2001291854A patent/AU2001291854A1/en not_active Abandoned
- 2001-09-11 TW TW090122488A patent/TWI306852B/zh not_active IP Right Cessation
- 2001-09-11 CA CA002418538A patent/CA2418538C/en not_active Expired - Lifetime
- 2001-09-11 WO PCT/EP2001/010502 patent/WO2002022580A1/en active IP Right Grant
- 2001-09-11 ES ES01972046T patent/ES2220809T3/es not_active Expired - Lifetime
- 2001-09-11 US US10/363,840 patent/US7169804B2/en not_active Expired - Lifetime
- 2001-09-11 AT AT01972046T patent/ATE264843T1/de active
- 2001-09-11 DE DE60102936T patent/DE60102936T2/de not_active Expired - Lifetime
-
2007
- 2007-01-12 US US11/652,812 patent/US7569587B2/en not_active Expired - Lifetime
-
2009
- 2009-04-07 US US12/384,580 patent/US20090209584A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1633415A (zh) | 2005-06-29 |
| CN1288134C (zh) | 2006-12-06 |
| WO2002022580A1 (en) | 2002-03-21 |
| BR0113837A (pt) | 2003-06-03 |
| BRPI0113837B1 (pt) | 2019-01-29 |
| BRPI0113837B8 (pt) | 2021-05-25 |
| CA2418538C (en) | 2009-12-22 |
| AU2001291854A1 (en) | 2002-03-26 |
| US20070135483A1 (en) | 2007-06-14 |
| JP5134181B2 (ja) | 2013-01-30 |
| TWI306852B (en) | 2009-03-01 |
| CA2418538A1 (en) | 2002-03-21 |
| HK1079506A1 (en) | 2006-04-07 |
| US7569587B2 (en) | 2009-08-04 |
| US20040102482A1 (en) | 2004-05-27 |
| EP1320525B1 (de) | 2004-04-21 |
| PE20020676A1 (es) | 2002-08-27 |
| JP2004509107A (ja) | 2004-03-25 |
| US20090209584A1 (en) | 2009-08-20 |
| MY133930A (en) | 2007-11-30 |
| US7169804B2 (en) | 2007-01-30 |
| PT1320525E (pt) | 2004-09-30 |
| DE60102936D1 (de) | 2004-05-27 |
| AR030651A1 (es) | 2003-08-27 |
| ES2220809T3 (es) | 2004-12-16 |
| DE60102936T2 (de) | 2005-03-24 |
| EP1320525A1 (de) | 2003-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| EEFA | Change of the company name |