ATE260108T1 - Verwendung von citicoline zur behandlung von multipler sklerose - Google Patents
Verwendung von citicoline zur behandlung von multipler skleroseInfo
- Publication number
- ATE260108T1 ATE260108T1 AT98960416T AT98960416T ATE260108T1 AT E260108 T1 ATE260108 T1 AT E260108T1 AT 98960416 T AT98960416 T AT 98960416T AT 98960416 T AT98960416 T AT 98960416T AT E260108 T1 ATE260108 T1 AT E260108T1
- Authority
- AT
- Austria
- Prior art keywords
- citicoline
- multiple sclerosis
- treat multiple
- disease
- als
- Prior art date
Links
- 229960001284 citicoline Drugs 0.000 title abstract 2
- RZZPDXZPRHQOCG-OJAKKHQRSA-N CDP-choline Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-N 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
- 208000016192 Demyelinating disease Diseases 0.000 abstract 2
- 208000026072 Motor neurone disease Diseases 0.000 abstract 2
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000005264 motor neuron disease Diseases 0.000 abstract 2
- RZZPDXZPRHQOCG-OJAKKHQRSA-M CDP-choline(1-) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-M 0.000 abstract 1
- 238000011284 combination treatment Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Control Of Stepping Motors (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6655697P | 1997-11-26 | 1997-11-26 | |
| US6701797P | 1997-12-01 | 1997-12-01 | |
| US12977898A | 1998-08-06 | 1998-08-06 | |
| PCT/US1998/025051 WO1999026633A1 (en) | 1997-11-26 | 1998-11-24 | Citicoline to treat motor neuron diseases and demyelinating diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260108T1 true ATE260108T1 (de) | 2004-03-15 |
Family
ID=27370993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98960416T ATE260108T1 (de) | 1997-11-26 | 1998-11-24 | Verwendung von citicoline zur behandlung von multipler sklerose |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1032402B1 (de) |
| JP (1) | JP2001523724A (de) |
| AT (1) | ATE260108T1 (de) |
| AU (1) | AU1601499A (de) |
| CA (1) | CA2311422A1 (de) |
| DE (1) | DE69821970T2 (de) |
| DK (1) | DK1032402T3 (de) |
| ES (1) | ES2216334T3 (de) |
| PT (1) | PT1032402E (de) |
| WO (1) | WO1999026633A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1053749A4 (de) * | 1998-02-03 | 2003-01-15 | Senju Pharma Co | Vorbeuge- und heilmittel für neurodegenerative erkrankungen |
| US20060094685A1 (en) * | 2002-07-11 | 2006-05-04 | Kazuki Endo | Medicinal composition for drug-induced neuropathy |
| EP3678675B1 (de) | 2017-09-08 | 2024-11-20 | TX Medic AB | Neue verwendung von dextransulfat |
| US20200215149A1 (en) * | 2019-01-08 | 2020-07-09 | Christopher David Thompson | N-Phenylacetyl-L-prolylglycine ethyl ester compositions and methods for using the same |
| RU2759654C1 (ru) * | 2020-12-14 | 2021-11-16 | Частное учреждение образовательная организация высшего образования "Медицинский университет "Реавиз" | Способ интраоперационной профилактики гипоксии головного мозга во время проведения каротидной эндартерэктомии |
| JPWO2023190797A1 (de) * | 2022-03-30 | 2023-10-05 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4569929A (en) * | 1980-02-29 | 1986-02-11 | Massachusetts Institute Of Technology | Cytidyl diphosphocholine-drug composition |
| DE3400276A1 (de) * | 1984-01-05 | 1985-07-18 | Ferrer Internacional S.A., Barcelona | Verwendung von cdp-cholin zur behandlung von neurologischen stoerungen |
| CN1036119C (zh) * | 1995-06-28 | 1997-10-15 | 北京格特生物工程科技开发公司 | 用于治疗视神经萎缩药物的复方制剂 |
-
1998
- 1998-11-24 DK DK98960416T patent/DK1032402T3/da active
- 1998-11-24 CA CA002311422A patent/CA2311422A1/en not_active Abandoned
- 1998-11-24 EP EP98960416A patent/EP1032402B1/de not_active Expired - Lifetime
- 1998-11-24 AT AT98960416T patent/ATE260108T1/de active
- 1998-11-24 JP JP2000521835A patent/JP2001523724A/ja active Pending
- 1998-11-24 AU AU16014/99A patent/AU1601499A/en not_active Abandoned
- 1998-11-24 PT PT98960416T patent/PT1032402E/pt unknown
- 1998-11-24 ES ES98960416T patent/ES2216334T3/es not_active Expired - Lifetime
- 1998-11-24 DE DE69821970T patent/DE69821970T2/de not_active Expired - Lifetime
- 1998-11-24 WO PCT/US1998/025051 patent/WO1999026633A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999026633A1 (en) | 1999-06-03 |
| EP1032402A1 (de) | 2000-09-06 |
| CA2311422A1 (en) | 1999-06-03 |
| ES2216334T3 (es) | 2004-10-16 |
| EP1032402B1 (de) | 2004-02-25 |
| AU1601499A (en) | 1999-06-15 |
| DE69821970D1 (de) | 2004-04-01 |
| JP2001523724A (ja) | 2001-11-27 |
| DE69821970T2 (de) | 2004-12-16 |
| PT1032402E (pt) | 2004-06-30 |
| DK1032402T3 (da) | 2004-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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