ATE259419T1 - Humanes cyr61, ein signalmolekül der extrazellulaeren matrix - Google Patents
Humanes cyr61, ein signalmolekül der extrazellulaeren matrixInfo
- Publication number
- ATE259419T1 ATE259419T1 AT97916018T AT97916018T ATE259419T1 AT E259419 T1 ATE259419 T1 AT E259419T1 AT 97916018 T AT97916018 T AT 97916018T AT 97916018 T AT97916018 T AT 97916018T AT E259419 T1 ATE259419 T1 AT E259419T1
- Authority
- AT
- Austria
- Prior art keywords
- ecm signalling
- signalling molecules
- mammalian ecm
- methods
- mammalian
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1395896P | 1996-03-15 | 1996-03-15 | |
PCT/US1997/004193 WO1997033995A2 (en) | 1996-03-15 | 1997-03-14 | Extracellular matrix signalling molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE259419T1 true ATE259419T1 (de) | 2004-02-15 |
Family
ID=21762734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97916018T ATE259419T1 (de) | 1996-03-15 | 1997-03-14 | Humanes cyr61, ein signalmolekül der extrazellulaeren matrix |
Country Status (11)
Country | Link |
---|---|
US (3) | US6413735B1 (de) |
EP (1) | EP0888452B1 (de) |
JP (1) | JP4307552B2 (de) |
CN (1) | CN1263852C (de) |
AT (1) | ATE259419T1 (de) |
AU (1) | AU733382B2 (de) |
CA (1) | CA2248549A1 (de) |
DE (1) | DE69727558T2 (de) |
DK (1) | DK0888452T3 (de) |
HK (1) | HK1018707A1 (de) |
WO (1) | WO1997033995A2 (de) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
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NZ271488A (en) | 1994-07-12 | 1998-01-26 | Human Genome Sciences Inc | Connective tissue growth factor-2 (ctgf-2) |
US7026299B2 (en) | 1994-07-12 | 2006-04-11 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
CN1263852C (zh) * | 1996-03-15 | 2006-07-12 | 穆尼恩公司 | 胞外基质信号分子 |
WO2001055210A2 (en) * | 2000-01-31 | 2001-08-02 | Munin Corporation | Human cyr61 |
US7521540B2 (en) | 1996-03-15 | 2009-04-21 | Munin Corporation | CYR61 compositions and methods |
US6562618B1 (en) * | 1997-12-25 | 2003-05-13 | Japan Tobacco, Inc. | Monoclonal antibody against connective tissue growth factor and medicinal uses thereof |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CN101818145A (zh) * | 1998-03-20 | 2010-09-01 | 联邦科学和工业研究组织 | 控制基因表达 |
ATE418730T1 (de) | 1998-08-20 | 2009-01-15 | Chugai Pharmaceutical Co Ltd | Verfahren zum screenen von potenziellen verbindungen für das auffinden von einem anti- tumor-arzneistoff |
ES2316372T3 (es) * | 1999-07-14 | 2009-04-16 | Novo Nordisk Health Care Ag | Uso de fviia o un agonista del factor tisular para regular la expresion genetica y la migracion celular o quimiotaxis. |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
CA2396062C (en) * | 1999-12-30 | 2009-11-17 | President And Fellows Of Harvard College | Methods and compositions relating to modulation of hepatocyte growth, plasma cell differentiation or t cell subset activity by modulation of xbp-1 activity |
EP1892250A3 (de) * | 2000-01-31 | 2008-09-17 | Munin Corporation | CYR61-Zusammensetzungen und Verfahren |
US8460367B2 (en) | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US7037332B2 (en) * | 2000-03-15 | 2006-05-02 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
AU2001271365A1 (en) * | 2000-06-21 | 2002-01-02 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
AU2001276868A1 (en) * | 2000-07-11 | 2002-01-21 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
DK1642885T3 (da) | 2000-08-29 | 2010-01-04 | Biocon Ltd | Anvendelse af et farmaceutisk præparat der indeholder et para-aminophenyl-eddikesyrederivat til behandling af inflammatoriske tilstande i mave-tarmkanalen |
JP2005508133A (ja) | 2001-01-11 | 2005-03-31 | キュラジェン コーポレイション | タンパク質およびそれをコードする核酸 |
US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
DK1572984T3 (en) | 2002-12-16 | 2016-06-13 | Technion Res & Dev Foundation | FEEDER CELL-FREE, XENOPHRIC CULTIVATION SYSTEM FOR HUMAN EMBRYONAL STEM CELLS |
WO2004090109A2 (en) * | 2003-03-31 | 2004-10-21 | Munin Corporation | Ccn3 compositions and methods |
JP2004315480A (ja) * | 2003-04-21 | 2004-11-11 | Yoshiyuki Kakehi | 前立腺疾患治療用医薬組成物 |
CN1835763B (zh) * | 2003-06-20 | 2011-04-20 | 妙甯公司 | Ccn1组合物和方法 |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
EP2338981B1 (de) | 2003-06-27 | 2015-04-22 | DePuy Synthes Products, LLC | Verwendung von von der Nabelschnur postpartum abgeleiteten Zellen zur Reparatur und Widerherstellung des Augengewebes |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US20050177885A1 (en) * | 2004-02-09 | 2005-08-11 | Lau Lester F. | CCN1 transgenic animals |
HUE028158T2 (en) | 2004-07-07 | 2016-12-28 | Biocon Ltd | Synthesis of bound immunoregulatory compounds |
CA2589041C (en) | 2004-12-23 | 2019-08-20 | Ethicon, Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
DK1835924T3 (da) | 2004-12-23 | 2013-11-04 | Ethicon Inc | Behandling af parkinsons sygdom og beslægtede sygdomme under anvendelse af postpartum opnåede celler |
US20070037186A1 (en) | 2005-05-20 | 2007-02-15 | Yuqiu Jiang | Thyroid fine needle aspiration molecular assay |
EP1962719A4 (de) | 2005-08-29 | 2011-05-04 | Technion Res And Dev Of Foundation Ltd | Medien zur züchtung von stammzellen |
WO2007070870A1 (en) | 2005-12-16 | 2007-06-21 | Ethicon, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
AU2006327073B2 (en) | 2005-12-19 | 2012-08-30 | Ethicon, Inc. | In vitro expansion of postpartum derived cells in roller bottles |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
DK2733203T3 (en) | 2006-08-02 | 2019-02-04 | Technion Res & Dev Foundation | PROCEDURES FOR EXPANSION OF EMBRYONAL STEM CELLS IN A SUSPENSION CULTURE |
CN102036688B (zh) | 2007-10-05 | 2014-07-02 | 伊西康公司 | 使用人脐带组织来源的细胞进行肾脏组织的修复和再生 |
US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
EP2237789B1 (de) * | 2007-12-27 | 2017-01-25 | DePuy Synthes Products, Inc. | Behandlung von bandscheibendegeneration anhand von zellen aus menschlichem nabelschnurgewebe |
US8940479B2 (en) * | 2008-01-14 | 2015-01-27 | Cornell University | Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity |
CN101747435B (zh) * | 2008-12-18 | 2013-06-19 | 上海市免疫学研究所 | 一种中和cyr61的单克隆抗体(杂交瘤)及其应用 |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
EP2379088B1 (de) | 2008-12-19 | 2018-02-28 | DePuy Synthes Products, Inc. | Behandlung von lungen und pulmonalen erkrankungen und störungen |
BRPI1013409A2 (pt) | 2009-03-26 | 2018-01-16 | Advanced Tech And Regenerative Medicine Llc | células de tecido de cordão umbilical humano como terapia para doença de alzheimer |
TW201102086A (en) | 2009-06-04 | 2011-01-16 | Hoffmann La Roche | Antibodies against human CCN1 and uses thereof |
US9018010B2 (en) | 2009-11-12 | 2015-04-28 | Technion Research & Development Foundation Limited | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
WO2011066783A1 (zh) * | 2009-12-04 | 2011-06-09 | 上海市免疫学研究所 | 抗Cyr61蛋白的单克隆抗体及其应用 |
DE102010010288A1 (de) | 2010-03-04 | 2011-09-08 | Wolfgang Poller | CCN1 zur Prävention und Therapie von entzündlichen Erkrankungen |
WO2011107590A1 (en) | 2010-03-04 | 2011-09-09 | Wolfgang Poller | Cnn1 (cyr61) for prevention and therapy of inflammatory disease |
CN103384824B (zh) * | 2010-12-06 | 2016-02-03 | Thd股份公司 | 癌症诊断方法及其用途 |
WO2012109238A2 (en) | 2011-02-07 | 2012-08-16 | President And Fellows Of Harvard College | Methods for increasing immune responses using agents that directly bind to and activate ire-1 |
SG11201403465PA (en) | 2011-12-23 | 2014-10-30 | Atrm Llc | Detection of human umbilical cord tissue-derived cells |
US20150018406A1 (en) | 2012-03-09 | 2015-01-15 | Cornell University | Modulation of breast cancer growth by modulation of xbp1 activity |
CN105263529B (zh) | 2013-04-12 | 2021-08-06 | 芒果基因制药公司 | 用于在脊椎动物个体中促进支架生物功能和伤口愈合的治疗性病毒微粒 |
WO2015013875A1 (zh) * | 2013-07-30 | 2015-02-05 | 杭州微基质生物科技有限公司 | 一种全能干细胞培养方法 |
ES2724300T3 (es) | 2013-09-25 | 2019-09-10 | Univ Cornell | Compuestos para inducir inmunidad antitumoral y métodos de lo mismo |
CN105396136B (zh) * | 2015-11-23 | 2018-10-30 | 上海交通大学医学院附属第九人民医院 | CCN1(Cyr61)在治疗皮肤损伤及皮肤萎缩相关疾病中的应用 |
US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
CN110938128B (zh) * | 2019-11-08 | 2021-07-13 | 上海交通大学 | 一种生物活性多肽pkcpkcdkevyfaervtsl及其制备方法和应用 |
CH716377B1 (it) * | 2020-08-05 | 2020-12-30 | Contrad Swiss Sa | Idrogel ad applicazione topica efficace nel prevenire e/o attenuare la degenerazione della cartilagine. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
JPH05255397A (ja) * | 1991-01-18 | 1993-10-05 | Bristol Myers Squibb Co | TGF−β誘導遺伝子系統群 |
US5770209A (en) | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
US5408040A (en) | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
ES2136092T3 (es) * | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
US5817310A (en) * | 1991-12-02 | 1998-10-06 | Cor Therapeutics, Inc. | Inhibitory immunoglobulin polypeptides to human PDGF beta receptor |
NZ271488A (en) | 1994-07-12 | 1998-01-26 | Human Genome Sciences Inc | Connective tissue growth factor-2 (ctgf-2) |
CN1263852C (zh) | 1996-03-15 | 2006-07-12 | 穆尼恩公司 | 胞外基质信号分子 |
WO1997034998A1 (en) | 1996-03-20 | 1997-09-25 | Human Genome Sciences, Inc. | Human cytokine polypeptide |
-
1997
- 1997-03-14 CN CNB971946094A patent/CN1263852C/zh not_active Expired - Fee Related
- 1997-03-14 AT AT97916018T patent/ATE259419T1/de not_active IP Right Cessation
- 1997-03-14 DE DE69727558T patent/DE69727558T2/de not_active Expired - Lifetime
- 1997-03-14 CA CA002248549A patent/CA2248549A1/en not_active Abandoned
- 1997-03-14 AU AU23296/97A patent/AU733382B2/en not_active Expired
- 1997-03-14 WO PCT/US1997/004193 patent/WO1997033995A2/en active IP Right Grant
- 1997-03-14 US US09/142,569 patent/US6413735B1/en not_active Expired - Fee Related
- 1997-03-14 JP JP53289897A patent/JP4307552B2/ja not_active Expired - Lifetime
- 1997-03-14 DK DK97916018T patent/DK0888452T3/da active
- 1997-03-14 EP EP97916018A patent/EP0888452B1/de not_active Expired - Lifetime
-
1999
- 1999-08-30 HK HK99103723A patent/HK1018707A1/xx not_active IP Right Cessation
-
2002
- 2002-01-22 US US10/053,753 patent/US7064185B2/en not_active Expired - Fee Related
-
2006
- 2006-06-19 US US11/455,506 patent/US20060257965A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK0888452T3 (da) | 2004-06-14 |
CN1263852C (zh) | 2006-07-12 |
US6413735B1 (en) | 2002-07-02 |
CA2248549A1 (en) | 1997-09-18 |
WO1997033995A2 (en) | 1997-09-18 |
US20020150986A1 (en) | 2002-10-17 |
US20060257965A1 (en) | 2006-11-16 |
EP0888452B1 (de) | 2004-02-11 |
JP4307552B2 (ja) | 2009-08-05 |
HK1018707A1 (en) | 2000-01-04 |
JP2000506732A (ja) | 2000-06-06 |
DE69727558T2 (de) | 2004-12-16 |
DE69727558D1 (de) | 2004-03-18 |
US7064185B2 (en) | 2006-06-20 |
EP0888452A2 (de) | 1999-01-07 |
AU2329697A (en) | 1997-10-01 |
AU733382B2 (en) | 2001-05-10 |
CN1222193A (zh) | 1999-07-07 |
WO1997033995A3 (en) | 1998-01-08 |
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