ATE258935T1 - Furo(3,2-b)pyridine als 5-ht1f agonisten - Google Patents

Furo(3,2-b)pyridine als 5-ht1f agonisten

Info

Publication number: ATE258935T1
Authority: AT; Austria
Prior art keywords: furo; pyridines; ht1f agonists; ht1f; agonists
Prior art date: 1999-02-26

Application number

AT00911678T

Other languages

English (en)

Inventor

Sandra Ann Filla

Brian Michael Mathes

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-26

Filing date

2000-02-11

Publication date

2004-02-15

2000-02-11 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2004-02-15 Application granted granted Critical

2004-02-15 Publication of ATE258935T1 publication Critical patent/ATE258935T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Anesthesiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT00911678T 1999-02-26 2000-02-11 Furo(3,2-b)pyridine als 5-ht1f agonisten ATE258935T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12201699P	1999-02-26	1999-02-26
PCT/US2000/002505 WO2000050426A2 (en)	1999-02-26	2000-02-11	Furo[3, 2-b]pyridines as 5-ht1f agonists

Publications (1)

Publication Number	Publication Date
ATE258935T1 true ATE258935T1 (de)	2004-02-15

Family

ID=22400069

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00911678T ATE258935T1 (de)	1999-02-26	2000-02-11	Furo(3,2-b)pyridine als 5-ht1f agonisten

Country Status (21)

Country	Link
EP (1)	EP1155020B1 (de)
JP (1)	JP2002537398A (de)
KR (1)	KR20010102355A (de)
AR (1)	AR026856A1 (de)
AT (1)	ATE258935T1 (de)
AU (1)	AU3354000A (de)
BR (1)	BR0008479A (de)
CA (1)	CA2371784A1 (de)
CO (1)	CO5150234A1 (de)
DE (1)	DE60008073T2 (de)
EA (1)	EA200100918A1 (de)
ES (1)	ES2214256T3 (de)
HU (1)	HUP0200245A2 (de)
ID (1)	ID30056A (de)
IL (1)	IL144355A0 (de)
NO (1)	NO20014127L (de)
PE (1)	PE20001432A1 (de)
PL (1)	PL350864A1 (de)
TR (1)	TR200102436T2 (de)
WO (1)	WO2000050426A2 (de)
ZA (1)	ZA200106109B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI263497B (en)	2002-03-29	2006-10-11	Lilly Co Eli	Pyridinoylpiperidines as 5-HT1F agonists
BRPI0409211A (pt)	2003-04-18	2006-03-28	Lilly Co Eli	composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto
UA82711C2 (en)	2003-09-12	2008-05-12	Эли Лилли Энд Компани	Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
DE602004008338T2 (de)	2003-12-17	2008-05-29	Eli Lilly And Co., Indianapolis	Substituierte (4-aminocyclohexen-1-yl) phenyl and (4-aminocyclohexen-1-yl) pyridinyl verbindungen als 5-ht1f agonisten
PL2413933T5 (pl)	2009-04-02	2021-10-18	Colucid Pharmaceuticals, Inc.	2,4,6-trifluoro-N-[6-(1-metylopiperydyno-4-karbonylo)pirydyn-2-ylo]benzamid do leczenia migreny drogą doustną lub dożylną
US8697876B2 (en)	2010-04-02	2014-04-15	Colucid Pharmaceuticals, Inc.	Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
EP2940022B1 (de) *	2014-04-30	2020-09-02	Masarykova Univerzita	Furopyridinen als Inhibitoren von Proteinkinasen
TWI826514B (zh)	2018-09-04	2023-12-21	美商美國禮來大藥廠	用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh)	2019-07-09	2022-09-01	美商美國禮來大藥廠	大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH11502816A (ja) *	1995-03-20	1999-03-09	イーライ・リリー・アンド・カンパニー	５−置換−３−（１，２，３，６−テトラヒドロピリジン−４−イル）−および３−（ピペリジン−４−イル）−１ｈ−インドール類：新規５−ｈｔ▲下１ｆ▼アゴニスト
FR2732969B1 (fr) *	1995-04-14	1997-05-16	Adir	Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1998011895A1 (en) *	1996-09-18	1998-03-26	Eli Lilly And Company	A method for the prevention of migraine

2000
- 2000-02-11 EP EP00911678A patent/EP1155020B1/de not_active Expired - Lifetime
- 2000-02-11 WO PCT/US2000/002505 patent/WO2000050426A2/en not_active Ceased
- 2000-02-11 BR BR0008479-4A patent/BR0008479A/pt not_active Application Discontinuation
- 2000-02-11 AU AU33540/00A patent/AU3354000A/en not_active Abandoned
- 2000-02-11 KR KR1020017010743A patent/KR20010102355A/ko not_active Withdrawn
- 2000-02-11 AT AT00911678T patent/ATE258935T1/de not_active IP Right Cessation
- 2000-02-11 HU HU0200245A patent/HUP0200245A2/hu unknown
- 2000-02-11 ID IDW00200101739D patent/ID30056A/id unknown
- 2000-02-11 EA EA200100918A patent/EA200100918A1/ru unknown
- 2000-02-11 CA CA002371784A patent/CA2371784A1/en not_active Abandoned
- 2000-02-11 TR TR2001/02436T patent/TR200102436T2/xx unknown
- 2000-02-11 ES ES00911678T patent/ES2214256T3/es not_active Expired - Lifetime
- 2000-02-11 DE DE60008073T patent/DE60008073T2/de not_active Expired - Fee Related
- 2000-02-11 JP JP2000601006A patent/JP2002537398A/ja not_active Withdrawn
- 2000-02-11 IL IL14435500A patent/IL144355A0/xx unknown
- 2000-02-11 PL PL00350864A patent/PL350864A1/xx not_active Application Discontinuation
- 2000-02-24 PE PE2000000153A patent/PE20001432A1/es not_active Application Discontinuation
- 2000-02-24 CO CO00013084A patent/CO5150234A1/es unknown
- 2000-02-24 AR ARP000100791A patent/AR026856A1/es unknown
2001
- 2001-07-25 ZA ZA200106109A patent/ZA200106109B/en unknown
- 2001-08-24 NO NO20014127A patent/NO20014127L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU3354000A (en)	2000-09-14
NO20014127D0 (no)	2001-08-24
DE60008073D1 (de)	2004-03-11
PL350864A1 (en)	2003-02-10
CA2371784A1 (en)	2000-08-31
BR0008479A (pt)	2002-01-29
PE20001432A1 (es)	2000-12-18
HUP0200245A2 (en)	2002-06-29
DE60008073T2 (de)	2004-08-05
TR200102436T2 (tr)	2002-06-21
AR026856A1 (es)	2003-03-05
WO2000050426A2 (en)	2000-08-31
NO20014127L (no)	2001-08-24
EP1155020A2 (de)	2001-11-21
WO2000050426A3 (en)	2000-12-21
ES2214256T3 (es)	2004-09-16
KR20010102355A (ko)	2001-11-15
CO5150234A1 (es)	2002-04-29
EP1155020B1 (de)	2004-02-04
ID30056A (id)	2001-11-01
ZA200106109B (en)	2002-07-25
EA200100918A1 (ru)	2002-02-28
IL144355A0 (en)	2002-05-23
JP2002537398A (ja)	2002-11-05

Publication	Publication Date	Title
PT1343786E (pt)	2005-11-30	Novos derivados de pirazolopiridina substituidos por piridina
DE60202200D1 (de)	2005-01-13	Imidazo[1,2-a]-pyridinderivate als mglur5 antagonisten
PT1218378E (pt)	2003-09-30	Derivados de terc-butil-(7-metil-imidazo-¬1,2-a\|-piridin-3-il)-amina
ATE293618T1 (de)	2005-05-15	4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
DZ3216A1 (fr)	2001-03-08	Inhibiteurs tricycliques de poly(adp-ribose) polymerases
ITMI20002358A0 (it)	2000-10-31	Derivati di tieno [2,3-c]isochinolin-3-one come inibitori della poli(adp-ribosio)polimerasi
DE60214428D1 (de)	2006-10-12	1, 4-dihydro-1, 4-diphenylpyridin-derivate
DE60021371D1 (de)	2005-08-25	Piperidinderivate verwendbar als ccr5 antagonisten
ATE270294T1 (de)	2004-07-15	1,2,3,4-tetrahydro-benzofuro(3,2-c)pyridin derivate
ATE258935T1 (de)	2004-02-15	Furo(3,2-b)pyridine als 5-ht1f agonisten
AU2679401A (en)	2001-08-20	Substituted 1,2,3,4- tetrahydroquinoline-2-carboxylic acid derivatives
NO20005485D0 (no)	2000-10-31	Orale preparater inneholdende 8-klor-6,11-dihydro-11-(4- piperyliden)-5H-benzo-[5,6]syklohepta[1,2-b]pyridin
DE60015471D1 (de)	2004-12-09	Chinolin-4-yl-derivate
NO20004906D0 (no)	2000-09-29	PDE IV-inhiberende pyridinderivater
DE60001054D1 (de)	2003-01-30	Trizyclische pyridin n-oxide vasopressin agonisten
AU7845701A (en)	2002-01-02	Heterocyclic aminoalkyl pyridine derivatives as psychopharmaceuticals
DK1088818T3 (da)	2005-03-14	Quinolin-4-yl-derivater
PT1317430E (pt)	2005-09-30	Derivados de (2-azabiciclo[2.2.1]hepta-7-il)-metanol como agonistas do receptor nocotinico de acetilcolina
ATE363485T1 (de)	2007-06-15	Benzothieno(3,2-c)pyridine als alpha2- antagonisten
NO20000183L (no)	2000-03-07	5-substituerte-3-oksadiazolyl-1,6-naftyridin-2(1H)-on- derivater
ID30349A (id)	2001-11-22	Turunan benzo (5,6) siklohepta (1,2-b) piridin untuk menghambat transferase protein farnesil
EP1359912A4 (de)	2006-05-03	Neue verfahren zur anwendung von pyridinderivaten
SK2226U (sk)	1999-07-12	Jablkovobazová šťava
DK1326866T3 (da)	2005-08-01	Substituerede 3,4-dihydro-pyrido[1,2-a]pyrimidiner
IT1308742B1 (it)	2002-01-10	Gruppo interruttore

Legal Events

Date	Code	Title	Description
2004-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties