ATE255572T1 - Mikrobielle transformationsprodukte - Google Patents
Mikrobielle transformationsprodukteInfo
- Publication number
- ATE255572T1 ATE255572T1 AT99955148T AT99955148T ATE255572T1 AT E255572 T1 ATE255572 T1 AT E255572T1 AT 99955148 T AT99955148 T AT 99955148T AT 99955148 T AT99955148 T AT 99955148T AT E255572 T1 ATE255572 T1 AT E255572T1
- Authority
- AT
- Austria
- Prior art keywords
- microbial transformation
- transformation products
- hydroxysordarin
- sordarin
- atcc
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 230000009466 transformation Effects 0.000 title 1
- 241000186046 Actinomyces Species 0.000 abstract 1
- 241000222122 Candida albicans Species 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 230000036983 biotransformation Effects 0.000 abstract 1
- 229940095731 candida albicans Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 244000053095 fungal pathogen Species 0.000 abstract 1
- OGGVRVMISBQNMQ-MDGIRFSOSA-N sordarin Chemical compound O[C@H]1[C@H](O)[C@H](OC)[C@@H](C)O[C@H]1OC[C@]1([C@@]2(C(C(C)C)=C3)C(O)=O)[C@H]3C[C@]2(C=O)[C@@H]2CC[C@@H](C)[C@H]2C1 OGGVRVMISBQNMQ-MDGIRFSOSA-N 0.000 abstract 1
- OGGVRVMISBQNMQ-UHFFFAOYSA-N sordarin Natural products OC1C(O)C(OC)C(C)OC1OCC1(C2(C(C(C)C)=C3)C(O)=O)C3CC2(C=O)C2CCC(C)C2C1 OGGVRVMISBQNMQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Confectionery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10566998P | 1998-10-26 | 1998-10-26 | |
| PCT/US1999/024865 WO2000024728A1 (en) | 1998-10-26 | 1999-10-22 | Microbial transformation product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE255572T1 true ATE255572T1 (de) | 2003-12-15 |
Family
ID=22307127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99955148T ATE255572T1 (de) | 1998-10-26 | 1999-10-22 | Mikrobielle transformationsprodukte |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6228622B1 (de) |
| EP (1) | EP1124813B1 (de) |
| JP (1) | JP2002528444A (de) |
| AT (1) | ATE255572T1 (de) |
| AU (1) | AU760975B2 (de) |
| CA (1) | CA2347803A1 (de) |
| DE (1) | DE69913369T2 (de) |
| ES (1) | ES2211191T3 (de) |
| WO (1) | WO2000024728A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020160441A1 (en) * | 1998-06-02 | 2002-10-31 | Merck & Co., Inc. | Protein elongation factor 2 as a target for antifungal and antiparasitic agents |
| WO2003007878A2 (en) * | 2001-07-18 | 2003-01-30 | Merck & Co., Inc. | Antifungal agents of sordarin derivatives |
| EP1458725B1 (de) * | 2001-12-14 | 2007-02-21 | Merck & Co., Inc. | Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittel |
| CN101807621B (zh) * | 2009-02-18 | 2012-01-18 | 财团法人工业技术研究院 | 太阳能电池模块修复装置与修复方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH465771A (de) | 1965-12-06 | 1968-11-30 | Sandoz Ag | Verfahren zur Herstellung eines neuen Antibioticums |
| EP0711784A1 (de) * | 1994-11-08 | 1996-05-15 | Glaxo, S.A. | Antifungale Sordarinderivate |
| SK88496A3 (en) | 1994-11-08 | 1997-04-09 | Glaxo Wellcome Sa | Cyclic derivatives, manufacturing process thereof, pharmaceutical compositions containing them and their use antifungal sordaridin derivatives |
| EP0711783A1 (de) | 1994-11-08 | 1996-05-15 | Glaxo, S.A. | Antifungale Sordarinderivate |
| EP0712859A1 (de) * | 1994-11-08 | 1996-05-22 | Glaxo, S.A. | Antifungale Sordarinderivate |
| US5972996A (en) * | 1997-08-22 | 1999-10-26 | Merck & Co., Inc. | 4-cyano-4-deformylsordarin derivatives |
| US5965612A (en) * | 1997-08-22 | 1999-10-12 | Merck & Co., Inc. | 4-cyano-4-deformylsordaricin derivatives |
-
1999
- 1999-10-22 JP JP2000578298A patent/JP2002528444A/ja not_active Withdrawn
- 1999-10-22 AU AU11320/00A patent/AU760975B2/en not_active Ceased
- 1999-10-22 WO PCT/US1999/024865 patent/WO2000024728A1/en active IP Right Grant
- 1999-10-22 EP EP99955148A patent/EP1124813B1/de not_active Expired - Lifetime
- 1999-10-22 AT AT99955148T patent/ATE255572T1/de not_active IP Right Cessation
- 1999-10-22 ES ES99955148T patent/ES2211191T3/es not_active Expired - Lifetime
- 1999-10-22 CA CA002347803A patent/CA2347803A1/en not_active Abandoned
- 1999-10-22 DE DE69913369T patent/DE69913369T2/de not_active Expired - Fee Related
- 1999-10-26 US US09/427,242 patent/US6228622B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69913369D1 (de) | 2004-01-15 |
| ES2211191T3 (es) | 2004-07-01 |
| WO2000024728A1 (en) | 2000-05-04 |
| JP2002528444A (ja) | 2002-09-03 |
| EP1124813A1 (de) | 2001-08-22 |
| US6228622B1 (en) | 2001-05-08 |
| EP1124813A4 (de) | 2002-01-23 |
| AU1132000A (en) | 2000-05-15 |
| CA2347803A1 (en) | 2000-05-04 |
| DE69913369T2 (de) | 2004-10-14 |
| AU760975B2 (en) | 2003-05-22 |
| EP1124813B1 (de) | 2003-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |