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ATE238339T1 - Verbindungen zur regulierung der meiose - Google Patents

Verbindungen zur regulierung der meiose

Info

Publication number
ATE238339T1
ATE238339T1 AT97948753T AT97948753T ATE238339T1 AT E238339 T1 ATE238339 T1 AT E238339T1 AT 97948753 T AT97948753 T AT 97948753T AT 97948753 T AT97948753 T AT 97948753T AT E238339 T1 ATE238339 T1 AT E238339T1
Authority
AT
Austria
Prior art keywords
compounds
meiosis
useful
compounds regulating
regulating meiosis
Prior art date
Application number
AT97948753T
Other languages
English (en)
Inventor
Christian Grondahl
Frederik Christian Gronvald
Peter Faarup
Anthony Murray
Jan Lund Ottesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE238339T1 publication Critical patent/ATE238339T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • General Induction Heating (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
AT97948753T 1996-12-20 1997-12-19 Verbindungen zur regulierung der meiose ATE238339T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK147896 1996-12-20
US4148897P 1997-02-11 1997-02-11
PCT/DK1997/000584 WO1998028323A1 (en) 1996-12-20 1997-12-19 Meiosis regulating compounds

Publications (1)

Publication Number Publication Date
ATE238339T1 true ATE238339T1 (de) 2003-05-15

Family

ID=26065809

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97948753T ATE238339T1 (de) 1996-12-20 1997-12-19 Verbindungen zur regulierung der meiose

Country Status (12)

Country Link
US (3) US6486145B2 (de)
EP (1) EP0946584B1 (de)
JP (1) JP2001506656A (de)
KR (1) KR20000069616A (de)
AT (1) ATE238339T1 (de)
AU (1) AU746878B2 (de)
CA (1) CA2275683A1 (de)
DE (1) DE69721304T2 (de)
HU (1) HUP9904616A3 (de)
IL (1) IL130249A0 (de)
NO (1) NO313144B1 (de)
WO (1) WO1998028323A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030004148A1 (en) * 1994-06-23 2003-01-02 Byskov Anne G. Regulation of meiosis
CA2331962A1 (en) * 1998-05-13 1999-11-18 Novo Nordisk A/S Meiosis regulating compounds
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
WO1999067273A1 (en) * 1998-06-19 1999-12-29 Novo Nordisk A/S Meiosis regulating compounds
US6528501B1 (en) 1998-12-11 2003-03-04 Akzo Nobel N.V. 22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
PL350557A1 (en) * 1999-02-10 2002-12-16 Schering Ag Unsaturated cholestane derivatives and their use for the preparation of meiosis regulating medicaments
AU2794000A (en) 1999-02-24 2000-09-14 Novo Nordisk A/S Treatment of infertility
ES2258445T3 (es) 1999-02-24 2006-09-01 Novo Nordisk A/S Metodo in vitro para la sincronizacion de la maduracion de ovocitos.
AU2914800A (en) * 1999-03-02 2000-09-21 Akzo Nobel N.V. (androst-5-en-17beta-yl)alkyl sulfoxides and sulfones and their use for control of fertility
DE60000978T2 (de) * 1999-03-09 2003-07-17 Akzo Nobel N.V., Arnheim/Arnhem 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose
US6902528B1 (en) * 1999-04-14 2005-06-07 Stereotaxis, Inc. Method and apparatus for magnetically controlling endoscopes in body lumens and cavities
EP1216059B1 (de) 1999-09-16 2005-10-19 Novo Nordisk A/S Zusammensetzung zur in-vitro befruchtung
EP1127890A1 (de) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
MXPA02007818A (es) * 2000-02-25 2002-10-23 Schering Ag Tasa de implantacion mejorada utilizando ff-mas.
WO2001076360A2 (en) * 2000-04-06 2001-10-18 Novo Nordisk A/S Synchronization of the cytoplasmatic and the nuclear maturation of oocytes in vitro
DE60225117T2 (de) * 2001-02-06 2009-02-26 Novo Nordisk A/S Behältnis mit niedrigem sauerstoffgehalt, das ff-mas enthält
US6988613B2 (en) 2001-02-06 2006-01-24 Novo Nordisk A/S Composition for IVF
EP1245572A1 (de) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol-Verbindungen, ihre Verwendung zur Herstellung Meiose-regulierender Medikamenten und ein Vefahren zu ihrer Herstellung
US8969543B2 (en) * 2003-04-03 2015-03-03 Bioneer Corporation SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof
US20080312673A1 (en) * 2007-06-05 2008-12-18 Viswanathan Raju R Method and apparatus for CTO crossing
WO2011127465A2 (en) 2010-04-09 2011-10-13 The Research Foundation Of The State University Of New York Ship inhibitors and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1224738B (de) 1960-12-29 1966-09-15 Takeda Chemical Industries Ltd Verfahren zur Herstellung von Cholestan-3, 5, 6-triol-3-estern oder -3, 6-diestern soowie von deren Salzen
DE1183079B (de) 1961-11-27 1964-12-10 Vismara Francesco Spa Verfahren zur Herstellung von gesaettigten 4-Hydroxy-3-keto-5alpha-steroiden
CH470374A (de) 1965-09-24 1969-03-31 Hoffmann La Roche Verfahren zur Herstellung von Steroiden
DE1593492A1 (de) 1966-01-29 1970-07-16 Schering Ag 6-Ketosteroide aus 20-Formyl-6-keto-Steroide
IL38540A0 (en) 1971-01-18 1972-03-28 Dauten Sa Method for the extraction of insect moulting steroid hormones
ZA725157B (en) 1971-07-29 1973-04-25 Dauten Sa New steroid of insecticide action and process for its production
US4670190A (en) 1973-01-10 1987-06-02 Hesse Robert H 1-α-hydroxy vitamin D compounds and process for preparing same
FR2219943B1 (de) 1973-03-02 1976-04-30 Eisai Co Ltd
IL41923A (en) 1973-04-01 1978-08-31 Yeda Res & Dev Preparation of hydroxylated derivatives of cholestanol and some such compounds
US3931403A (en) 1973-05-25 1976-01-06 Intellectual Property Development Corporation Antimicrobial compositions
US3887545A (en) 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
JPS5119752A (en) 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho
IL45897A (en) 1974-10-22 1978-12-17 Yeda Res & Dev Process for the preparation of 1 hydroxy-provitamin d3
JPS6039278B2 (ja) 1977-05-23 1985-09-05 中外製薬株式会社 ステロイド誘導体
EP0055999B1 (de) 1979-02-15 1984-10-03 Teijin Limited Vitamin D3
US4230626A (en) 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
US4254045A (en) 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
GB2089810B (en) 1980-09-22 1984-09-19 Wisconsin Alumni Res Found 23,25-dihydroxyvitamin d3 precursors
ATE15050T1 (de) 1981-04-29 1985-09-15 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten und zwischenprodukte dafuer.
US4329295A (en) 1981-06-29 1982-05-11 G. D. Searle & Co. 24-Cyclopropylcholene-3β, 22-diols and esters thereof
US4348328A (en) 1981-11-09 1982-09-07 G.D. Searle & Co. 25-Substituted-5α-cholestane-3β,22S-diol
US4871727A (en) 1987-12-21 1989-10-03 Merck & Co, Inc. Anti-inflammatory and antidegenerative compounds isolated from L-681,512
JPH0749435B2 (ja) 1988-07-04 1995-05-31 帝人株式会社 1α,3β,24−トリヒドロキシ−△▲上5▼−ステロイド類の製造方法
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
RU2188006C2 (ru) * 1995-03-06 2002-08-27 Ново Нордиск А/С Стимуляция мейоза

Also Published As

Publication number Publication date
JP2001506656A (ja) 2001-05-22
NO993009D0 (no) 1999-06-18
DE69721304D1 (de) 2003-05-28
US20010005757A1 (en) 2001-06-28
HUP9904616A3 (en) 2001-02-28
AU7878998A (en) 1998-07-17
CA2275683A1 (en) 1998-07-02
US20030032824A1 (en) 2003-02-13
DE69721304T2 (de) 2004-03-04
NO993009L (no) 1999-08-19
KR20000069616A (ko) 2000-11-25
US20050004382A1 (en) 2005-01-06
NO313144B1 (no) 2002-08-19
IL130249A0 (en) 2000-06-01
US6759400B2 (en) 2004-07-06
US6486145B2 (en) 2002-11-26
AU746878B2 (en) 2002-05-02
EP0946584A1 (de) 1999-10-06
EP0946584B1 (de) 2003-04-23
WO1998028323A1 (en) 1998-07-02
HUP9904616A2 (hu) 2000-06-28

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