ATE238072T1 - Verbesserungen an (oder im bezug auf) kontrastmittel - Google Patents
Verbesserungen an (oder im bezug auf) kontrastmittelInfo
- Publication number
- ATE238072T1 ATE238072T1 AT97905222T AT97905222T ATE238072T1 AT E238072 T1 ATE238072 T1 AT E238072T1 AT 97905222 T AT97905222 T AT 97905222T AT 97905222 T AT97905222 T AT 97905222T AT E238072 T1 ATE238072 T1 AT E238072T1
- Authority
- AT
- Austria
- Prior art keywords
- relating
- contrast agents
- agents
- contrast
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9603466.5A GB9603466D0 (en) | 1996-02-19 | 1996-02-19 | Improvements in or relating to contrast agents |
GBGB9611894.8A GB9611894D0 (en) | 1996-06-07 | 1996-06-07 | Improvements in or relating to contrast agents |
GBGB9625663.1A GB9625663D0 (en) | 1996-12-11 | 1996-12-11 | Improvements in or relating to contrast agents |
PCT/GB1997/000459 WO1997029783A1 (en) | 1996-02-19 | 1997-02-19 | Improvements in or relating to contrast agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE238072T1 true ATE238072T1 (de) | 2003-05-15 |
Family
ID=27268137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97905222T ATE238072T1 (de) | 1996-02-19 | 1997-02-19 | Verbesserungen an (oder im bezug auf) kontrastmittel |
Country Status (25)
Country | Link |
---|---|
US (4) | US6221337B1 (de) |
EP (2) | EP0881915B1 (de) |
JP (1) | JP4418033B2 (de) |
KR (1) | KR100500334B1 (de) |
CN (1) | CN1278740C (de) |
AP (1) | AP890A (de) |
AT (1) | ATE238072T1 (de) |
AU (1) | AU726503B2 (de) |
BG (1) | BG102758A (de) |
CA (1) | CA2246779C (de) |
CZ (1) | CZ293986B6 (de) |
DE (1) | DE69721235T2 (de) |
EA (1) | EA001135B1 (de) |
EE (1) | EE04224B1 (de) |
ES (1) | ES2197986T3 (de) |
HK (1) | HK1014872A1 (de) |
HU (1) | HU229090B1 (de) |
IL (1) | IL125748A (de) |
NZ (1) | NZ331509A (de) |
OA (1) | OA10839A (de) |
PL (1) | PL328406A1 (de) |
PT (1) | PT881915E (de) |
SK (1) | SK284200B6 (de) |
TR (1) | TR199801613T2 (de) |
WO (1) | WO1997029783A1 (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL128345A0 (en) * | 1996-08-02 | 2000-01-31 | Nycomed Imaging As | Improvements in or relating to contrast agents |
AU784367B2 (en) * | 1996-08-02 | 2006-03-16 | Ge Healthcare As | Improvements in or relating to contrast agents |
EP0968000B1 (de) * | 1997-08-12 | 2003-10-29 | Bracco Research S.A. | Verabreichbare formulierugen und ihre anwendung in mri |
GB9717476D0 (en) * | 1997-08-18 | 1997-10-22 | Nycomed Imaging As | Process |
GB9717588D0 (en) * | 1997-08-19 | 1997-10-22 | Nycomed Imaging As | Improvements in or relating to contrast agents |
GB9717542D0 (en) * | 1997-08-19 | 1997-10-22 | Nycomed Imaging As | Process |
GB9717589D0 (en) * | 1997-08-19 | 1997-10-22 | Nycomed Imaging As | Improvements in or relating to contrast agents |
GB9726773D0 (en) * | 1997-12-18 | 1998-02-18 | Nycomed Imaging As | Improvements in or relating to ultrasonagraphy |
IL139034A0 (en) * | 1998-04-28 | 2001-11-25 | Nycomed Imaging As | Improvements in or relating to separation processes |
GB9813568D0 (en) | 1998-06-23 | 1998-08-19 | Nycomed Imaging As | Improvements in or relating to cardiac imaging |
US6514209B1 (en) | 1999-06-07 | 2003-02-04 | Drexel University | Method of enhancing ultrasonic techniques via measurement of ultraharmonic signals |
US20030103960A1 (en) * | 1999-12-22 | 2003-06-05 | Pierre Philippart | Sealant and bone generating product |
CA2410887C (en) | 2000-06-02 | 2012-07-24 | Bracco Research Usa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
NO20004795D0 (no) | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
US6984373B2 (en) | 2000-12-23 | 2006-01-10 | Dyax Corp. | Fibrin binding moieties useful as imaging agents |
KR100373712B1 (ko) * | 2000-12-23 | 2003-02-25 | 사회복지법인삼성생명공익재단(삼성서울병원) | 초음파 조영제 및 그의 제조방법 |
EP1387637B1 (de) | 2001-04-06 | 2007-10-31 | Bracco Research S.A. | Vorrichtung zur Messung lokaler physikalischer Parameter in einem flüssigkeitsgefüllten Hohlraum |
AU2003205930B2 (en) * | 2002-02-01 | 2007-08-16 | Shimoda Biotech (Pty) Ltd | Pharmaceutical composition |
WO2003074005A2 (en) | 2002-03-01 | 2003-09-12 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
AU2003278807A1 (en) | 2002-03-01 | 2004-08-13 | Bracco International B.V. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US7211240B2 (en) | 2002-03-01 | 2007-05-01 | Bracco International B.V. | Multivalent constructs for therapeutic and diagnostic applications |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
NO20024755D0 (no) * | 2002-10-03 | 2002-10-03 | Amersham Health As | Metode |
EP1572001A1 (de) | 2002-11-29 | 2005-09-14 | Amersham Health AS | Ultraschallauflösende methode |
EP1590006B1 (de) * | 2003-02-04 | 2010-09-08 | Bracco Suisse SA | Ultraschall kontrastmittel und verfahren zur erstellung |
US20070128117A1 (en) * | 2003-02-04 | 2007-06-07 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
JP5466350B2 (ja) | 2003-03-03 | 2014-04-09 | ダイアックス、コープ | HGFレセプター(cMet)を特異的に結合するペプチドおよびその使用 |
JP2007522085A (ja) * | 2003-06-27 | 2007-08-09 | スミスクライン・ビーチャム・コーポレイション | 安定化されたトポテカンリポソーム組成物および方法 |
US20050019379A1 (en) | 2003-07-22 | 2005-01-27 | Kimberly-Clark Worldwide, Inc. | Wipe and methods for improving skin health |
NO20035401D0 (no) * | 2003-12-04 | 2003-12-04 | Amersham Health As | Metode |
JP5513708B2 (ja) * | 2003-12-22 | 2014-06-04 | ブラッコ・シュイス・ソシエテ・アノニム | 造影イメージング用の気体封入マイクロベシクル・アセンブリー |
JP2007515471A (ja) * | 2003-12-22 | 2007-06-14 | ブラッコ・リサーチ・ソシエテ・アノニム | 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー |
US7025726B2 (en) | 2004-01-22 | 2006-04-11 | The Regents Of The University Of Nebraska | Detection of endothelial dysfunction by ultrasonic imaging |
EP1784228B1 (de) | 2004-08-18 | 2016-10-05 | Bracco Suisse SA | Gasgefüllte mikrovesikelzusammensetzung für kontrastbilddarstellungen |
WO2006044996A2 (en) * | 2004-10-15 | 2006-04-27 | The Trustees Of Columbia University In The City Of New York | System and method for automated boundary detection of body structures |
WO2006044997A2 (en) * | 2004-10-15 | 2006-04-27 | The Trustees Of Columbia University In The City Of New York | System and method for localized measurement and imaging of viscosity of tissues |
CN100574809C (zh) * | 2005-01-10 | 2009-12-30 | 重庆海扶(Hifu)技术有限公司 | 一种高强度聚焦超声治疗用氟碳乳剂类助剂及其应用 |
CN100427142C (zh) * | 2005-01-10 | 2008-10-22 | 重庆海扶(Hifu)技术有限公司 | 一种高强度聚焦超声治疗用助剂及其筛选方法 |
US10687785B2 (en) | 2005-05-12 | 2020-06-23 | The Trustees Of Columbia Univeristy In The City Of New York | System and method for electromechanical activation of arrhythmias |
WO2007035721A2 (en) * | 2005-09-19 | 2007-03-29 | The Trustees Of Columbia University In The City Of New York | Ultrasound method to open blood brain barrier |
CA2826960A1 (en) | 2005-12-09 | 2007-06-14 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
EP1797919A1 (de) | 2005-12-16 | 2007-06-20 | Bracco Research S.A. | Vorrichtung zum Übertragen von Flüssigkeiten für Behälter zur Abgabe von Medikamenten |
WO2007088051A2 (en) | 2006-01-31 | 2007-08-09 | Bayer Schering Pharma Aktiengesellschaft | Modulation of mdl-1 activity for treatment of inflammatory disease |
CA2659645C (en) | 2006-08-01 | 2015-06-30 | Martijn E. Frijlink | Pulse inversion sequences for nonlinear imaging |
WO2008027520A2 (en) * | 2006-08-30 | 2008-03-06 | The Trustees Of Columbia University In The City Of New York | Systems and methods for composite elastography and wave imaging |
US9446156B2 (en) | 2006-09-05 | 2016-09-20 | Bracco Suisse S.A. | Gas-filled microvesicles with polymer-modified lipids |
EP2005970A1 (de) | 2007-06-22 | 2008-12-24 | Berlin Science Partners GmbH i.V. | Bildgebende Diagnostik durch Kombination von Kontrastmitteln |
JP2010005512A (ja) * | 2008-06-25 | 2010-01-14 | Kao Corp | 微細気泡前駆体組成物 |
GB0811856D0 (en) * | 2008-06-27 | 2008-07-30 | Ucl Business Plc | Magnetic microbubbles, methods of preparing them and their uses |
WO2010014977A1 (en) | 2008-08-01 | 2010-02-04 | The Trustees Of Columbia University In The City Of New York | Systems and methods for matching and imaging tissue characteristics |
WO2010030819A1 (en) | 2008-09-10 | 2010-03-18 | The Trustees Of Columbia University In The City Of New York | Systems and methods for opening a tissue |
EP2334239A4 (de) * | 2008-09-10 | 2011-10-19 | Univ Columbia | Isolierung von mikrobläschen eines bestimmten grössenbereichs aus polydispersen mikrobläschen |
EP2470287A4 (de) | 2009-08-28 | 2015-01-21 | Univ Columbia | Systeme, verfahren und vorrichtungen zur herstellung gasgefüllter mikroblasen |
US9107950B2 (en) * | 2009-09-15 | 2015-08-18 | The Trustees Of Columbia University In The City Of New York | Systems, methods, and devices for microbubbles |
EP2480144B1 (de) | 2009-09-21 | 2024-03-06 | The Trustees of Columbia University in the City of New York | Systeme zur öffnung einer gewebebarriere |
WO2011035254A1 (en) * | 2009-09-21 | 2011-03-24 | Drexel University | Stabilized ultrasound contrast agent |
US8834846B2 (en) | 2010-05-06 | 2014-09-16 | Bruker Biospin Corporation | Fluorescent NIRF activatable probes for disease detection |
WO2012019172A1 (en) * | 2010-08-06 | 2012-02-09 | The Trustees Of Columbia University In The City Of New York | Medical imaging contrast devices, methods, and systems |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
WO2012162664A1 (en) | 2011-05-26 | 2012-11-29 | The Trustees Of Columbia University In The City Of New York | Systems and methods for opening of a tissue barrier in primates |
RU2631800C2 (ru) | 2012-04-30 | 2017-09-26 | ДжиИ Хелткер АС | Способ заполнения контейнера вспениваемой композицией |
DK2864033T3 (en) | 2012-06-26 | 2016-05-17 | Ge Healthcare As | PREPARATION OF COMPOSITION INCLUDING GAS MICROBOBLES |
WO2014059170A1 (en) | 2012-10-10 | 2014-04-17 | The Trustees Of Columbia University In The City Of New York | Systems and methods for mechanical mapping of cardiac rhythm |
CN105026030B (zh) | 2012-12-21 | 2017-04-12 | 博莱科瑞士股份有限公司 | 充气微泡 |
US9255907B2 (en) | 2013-03-14 | 2016-02-09 | Empire Technology Development Llc | Identification of surgical smoke |
CN105050614B (zh) | 2013-03-15 | 2019-04-05 | 加利福尼亚大学董事会 | 刺激胆固醇流出的具有降低的毒性的肽 |
US9247921B2 (en) | 2013-06-07 | 2016-02-02 | The Trustees Of Columbia University In The City Of New York | Systems and methods of high frame rate streaming for treatment monitoring |
US10322178B2 (en) | 2013-08-09 | 2019-06-18 | The Trustees Of Columbia University In The City Of New York | Systems and methods for targeted drug delivery |
US10028723B2 (en) | 2013-09-03 | 2018-07-24 | The Trustees Of Columbia University In The City Of New York | Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening |
GB201405735D0 (en) * | 2014-03-31 | 2014-05-14 | Ge Healthcare As | Ultrasound precursor preparation method |
CA2968478C (en) | 2014-12-18 | 2021-10-12 | Bracco Suisse Sa | Targeted gas-filled microvesicles formulation |
CN107708742B (zh) * | 2015-06-10 | 2021-01-15 | 学校法人帝京大学 | 诊断治疗用气泡制剂(tb)及其使用方法 |
CN107233583B (zh) * | 2016-03-29 | 2020-04-24 | 北京飞锐达医疗科技有限公司 | 一种具有超长持续时间的超声造影剂及其制备方法 |
GB201821049D0 (en) * | 2018-12-21 | 2019-02-06 | Ge Healthcare As | Ultrasound contrast agent and methods for use therof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
IN172208B (de) * | 1990-04-02 | 1993-05-01 | Sint Sa | |
US5445813A (en) * | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
DE4100470A1 (de) * | 1991-01-09 | 1992-07-16 | Byk Gulden Lomberg Chem Fab | Echokontrastmittel |
GB9106673D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
DE4328642A1 (de) * | 1993-08-26 | 1995-03-02 | Byk Gulden Lomberg Chem Fab | Ultraschallkontrastmittel |
GB9511488D0 (en) * | 1995-06-07 | 1995-08-02 | Nycomed Imaging As | Improvements in or relating to contrast agents |
US5846517A (en) * | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
-
1997
- 1997-02-19 NZ NZ331509A patent/NZ331509A/xx unknown
- 1997-02-19 EP EP97905222A patent/EP0881915B1/de not_active Expired - Lifetime
- 1997-02-19 AP APAP/P/1998/001319A patent/AP890A/en active
- 1997-02-19 PL PL97328406A patent/PL328406A1/xx unknown
- 1997-02-19 EA EA199800745A patent/EA001135B1/ru active IP Right Revival
- 1997-02-19 JP JP52913197A patent/JP4418033B2/ja not_active Expired - Lifetime
- 1997-02-19 DE DE69721235T patent/DE69721235T2/de not_active Expired - Lifetime
- 1997-02-19 CN CNB971931895A patent/CN1278740C/zh not_active Expired - Lifetime
- 1997-02-19 ES ES97905222T patent/ES2197986T3/es not_active Expired - Lifetime
- 1997-02-19 PT PT97905222T patent/PT881915E/pt unknown
- 1997-02-19 CZ CZ19982625A patent/CZ293986B6/cs not_active IP Right Cessation
- 1997-02-19 WO PCT/GB1997/000459 patent/WO1997029783A1/en not_active Application Discontinuation
- 1997-02-19 CA CA002246779A patent/CA2246779C/en not_active Expired - Lifetime
- 1997-02-19 AT AT97905222T patent/ATE238072T1/de not_active IP Right Cessation
- 1997-02-19 HU HU9900813A patent/HU229090B1/hu unknown
- 1997-02-19 AU AU18847/97A patent/AU726503B2/en not_active Ceased
- 1997-02-19 KR KR10-1998-0706415A patent/KR100500334B1/ko active IP Right Grant
- 1997-02-19 EE EE9800249A patent/EE04224B1/xx not_active IP Right Cessation
- 1997-02-19 EP EP03008699A patent/EP1331013A3/de not_active Withdrawn
- 1997-02-19 IL IL12574897A patent/IL125748A/en not_active IP Right Cessation
- 1997-02-19 TR TR1998/01613T patent/TR199801613T2/xx unknown
- 1997-02-19 SK SK1126-98A patent/SK284200B6/sk unknown
-
1998
- 1998-08-14 OA OA9800144A patent/OA10839A/en unknown
- 1998-08-19 US US09/136,410 patent/US6221337B1/en not_active Expired - Lifetime
- 1998-09-09 BG BG102758A patent/BG102758A/xx unknown
-
1999
- 1999-01-08 HK HK99100075A patent/HK1014872A1/xx unknown
-
2001
- 2001-02-15 US US09/783,793 patent/US20010010811A1/en not_active Abandoned
-
2002
- 2002-11-22 US US10/302,800 patent/US20030202942A1/en not_active Abandoned
-
2005
- 2005-03-04 US US11/073,027 patent/US20050201942A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 0881915 Country of ref document: EP |
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EEFA | Change of the company name | ||
REN | Ceased due to non-payment of the annual fee |