ATE237616T1 - Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)- 2-cyclopenten-1-methanol in hbv - Google Patents
Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)- 2-cyclopenten-1-methanol in hbvInfo
- Publication number
- ATE237616T1 ATE237616T1 AT00902768T AT00902768T ATE237616T1 AT E237616 T1 ATE237616 T1 AT E237616T1 AT 00902768 T AT00902768 T AT 00902768T AT 00902768 T AT00902768 T AT 00902768T AT E237616 T1 ATE237616 T1 AT E237616T1
- Authority
- AT
- Austria
- Prior art keywords
- methanol
- amino
- cyclopent
- hbv
- purine
- Prior art date
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Substances OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 title 1
- COZAZKCWQGBJDE-JGVFFNPUSA-N [(1r,4s)-4-(6-aminopurin-9-yl)cyclopent-2-en-1-yl]methanol Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@H]1C[C@@H](CO)C=C1 COZAZKCWQGBJDE-JGVFFNPUSA-N 0.000 abstract 1
- 208000002672 hepatitis B Diseases 0.000 abstract 1
- 238000013160 medical therapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9903091.8A GB9903091D0 (en) | 1999-02-12 | 1999-02-12 | Therapeutic nucleoside compound |
| PCT/GB2000/000429 WO2000047581A1 (en) | 1999-02-12 | 2000-02-11 | Therapeutic nucleoside compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237616T1 true ATE237616T1 (de) | 2003-05-15 |
Family
ID=10847550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00902768T ATE237616T1 (de) | 1999-02-12 | 2000-02-11 | Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)- 2-cyclopenten-1-methanol in hbv |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6630477B1 (de) |
| EP (1) | EP1150981B1 (de) |
| JP (1) | JP2002536448A (de) |
| KR (1) | KR20010102081A (de) |
| CN (1) | CN1346356A (de) |
| AT (1) | ATE237616T1 (de) |
| AU (1) | AU2450900A (de) |
| DE (1) | DE60002172T2 (de) |
| DK (1) | DK1150981T3 (de) |
| ES (1) | ES2195861T3 (de) |
| GB (1) | GB9903091D0 (de) |
| HK (1) | HK1039935B (de) |
| PT (1) | PT1150981E (de) |
| WO (1) | WO2000047581A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8496910B2 (en) * | 2006-06-21 | 2013-07-30 | Ge Healthcare As | Stabilisation of radiopharmaceutical precursors |
| WO2019099595A1 (en) * | 2017-11-14 | 2019-05-23 | The Schepens Eye Research Institute, Inc. | NANO-EMULSION OF CBFβ-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVERY |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK175131B1 (da) * | 1988-01-20 | 2004-06-14 | Univ Minnesota | 4-(9H-Purin-9-yl)-2-cyclopentenylcarbinoler, farmaceutiske præparater indeholdende forbindelserne samt mellemprodukter derfor |
| US4916224A (en) | 1988-01-20 | 1990-04-10 | Regents Of The University Of Minnesota | Dideoxycarbocyclic nucleosides |
| NZ229453A (en) * | 1988-06-10 | 1991-08-27 | Univ Minnesota & Southern Rese | A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents |
| GB8815265D0 (en) * | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
| EP0366385B1 (de) | 1988-10-24 | 1993-06-09 | The Wellcome Foundation Limited | Guaninderivate mit antiviraler Wirkung und deren pharmazeutisch verträgliche Salze |
| MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
| EP0468119A1 (de) * | 1990-07-24 | 1992-01-29 | Merrell Dow Pharmaceuticals Inc. | Neue Carbocyclische Analoge einiger Nukleoside |
| JPH06199812A (ja) * | 1991-02-12 | 1994-07-19 | Takeda Chem Ind Ltd | 新規シクロペンテン誘導体 |
| GB9417249D0 (en) * | 1994-08-26 | 1994-10-19 | Wellcome Found | A novel salt |
-
1999
- 1999-02-12 GB GBGB9903091.8A patent/GB9903091D0/en not_active Ceased
-
2000
- 2000-02-11 EP EP00902768A patent/EP1150981B1/de not_active Expired - Lifetime
- 2000-02-11 AU AU24509/00A patent/AU2450900A/en not_active Abandoned
- 2000-02-11 JP JP2000598501A patent/JP2002536448A/ja active Pending
- 2000-02-11 KR KR1020017010197A patent/KR20010102081A/ko not_active Application Discontinuation
- 2000-02-11 DE DE60002172T patent/DE60002172T2/de not_active Expired - Lifetime
- 2000-02-11 WO PCT/GB2000/000429 patent/WO2000047581A1/en not_active Application Discontinuation
- 2000-02-11 AT AT00902768T patent/ATE237616T1/de active
- 2000-02-11 DK DK00902768T patent/DK1150981T3/da active
- 2000-02-11 ES ES00902768T patent/ES2195861T3/es not_active Expired - Lifetime
- 2000-02-11 CN CN00806018A patent/CN1346356A/zh active Pending
- 2000-02-11 US US09/913,309 patent/US6630477B1/en not_active Expired - Lifetime
- 2000-02-11 PT PT00902768T patent/PT1150981E/pt unknown
-
2002
- 2002-02-21 HK HK02101285.0A patent/HK1039935B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1150981A1 (de) | 2001-11-07 |
| US6630477B1 (en) | 2003-10-07 |
| AU2450900A (en) | 2000-08-29 |
| EP1150981B1 (de) | 2003-04-16 |
| GB9903091D0 (en) | 1999-03-31 |
| WO2000047581A1 (en) | 2000-08-17 |
| KR20010102081A (ko) | 2001-11-15 |
| DE60002172D1 (de) | 2003-05-22 |
| PT1150981E (pt) | 2003-08-29 |
| CN1346356A (zh) | 2002-04-24 |
| DK1150981T3 (da) | 2003-07-21 |
| HK1039935B (zh) | 2003-12-19 |
| HK1039935A1 (en) | 2002-05-17 |
| DE60002172T2 (de) | 2003-11-27 |
| JP2002536448A (ja) | 2002-10-29 |
| ES2195861T3 (es) | 2003-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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