ATE229516T1 - Benzofuran-4-carboxamide - Google Patents
Benzofuran-4-carboxamideInfo
- Publication number
- ATE229516T1 ATE229516T1 AT97942858T AT97942858T ATE229516T1 AT E229516 T1 ATE229516 T1 AT E229516T1 AT 97942858 T AT97942858 T AT 97942858T AT 97942858 T AT97942858 T AT 97942858T AT E229516 T1 ATE229516 T1 AT E229516T1
- Authority
- AT
- Austria
- Prior art keywords
- benzofuran
- carboxamide
- substituted
- optionally
- flourine
- Prior art date
Links
- MZAUQUVYPHLLDF-UHFFFAOYSA-N 1-benzofuran-4-carboxamide Chemical compound NC(=O)C1=CC=CC2=C1C=CO2 MZAUQUVYPHLLDF-UHFFFAOYSA-N 0.000 title 1
- PIEXCQIOSMOEOU-UHFFFAOYSA-N 1-bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione Chemical group CC1(C)N(Br)C(=O)N(Cl)C1=O PIEXCQIOSMOEOU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Table Devices Or Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19633052 | 1996-08-19 | ||
| PCT/EP1997/004398 WO1998007715A1 (de) | 1996-08-19 | 1997-08-13 | Novel benzofuran-4-carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE229516T1 true ATE229516T1 (de) | 2002-12-15 |
Family
ID=7802799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97942858T ATE229516T1 (de) | 1996-08-19 | 1997-08-13 | Benzofuran-4-carboxamide |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6211203B1 (de) |
| EP (1) | EP0923568B9 (de) |
| JP (1) | JP4309475B2 (de) |
| AT (1) | ATE229516T1 (de) |
| AU (1) | AU4454597A (de) |
| CY (1) | CY2458B1 (de) |
| DE (1) | DE69717827T2 (de) |
| DK (1) | DK0923568T5 (de) |
| ES (1) | ES2188983T4 (de) |
| PT (1) | PT923568E (de) |
| WO (1) | WO1998007715A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL329912A1 (en) * | 1996-05-20 | 1999-04-26 | Darwin Discovery Ltd | Benzofurane carboxyamides and their therapeutic applications |
| CN1290266A (zh) * | 1998-02-09 | 2001-04-04 | 达尔文发现有限公司 | 苯并呋喃－4－甲酰胺和其治疗用途 |
| TW555759B (en) * | 1998-06-08 | 2003-10-01 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| DE59906365D1 (de) * | 1998-06-10 | 2003-08-28 | Altana Pharma Ag | Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4 |
| CA2345459A1 (en) * | 1998-11-12 | 2000-05-18 | Regine Bohacek | Bicyclic signal transduction inhibitors, compositions containing them & uses thereof |
| DE19924340A1 (de) | 1999-05-27 | 2000-11-30 | Basf Ag | Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren |
| SK287231B6 (sk) | 1999-08-21 | 2010-04-07 | Nycomed Gmbh | Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora |
| GB0003257D0 (en) | 2000-02-11 | 2000-04-05 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| AU2004226353A1 (en) | 2003-04-01 | 2004-10-14 | Laboratoires Serono Sa | Inhibitors of phosphodiesterases in infertility |
| EP2275096A3 (de) | 2005-08-26 | 2011-07-13 | Braincells, Inc. | Neurogenese durch modulation des Muscarinrezeptors |
| EP2258359A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin |
| EP1940389A2 (de) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation von neurogenese durch pde-hemmung |
| JP2009513672A (ja) | 2005-10-31 | 2009-04-02 | ブレインセルス，インコーポレイティド | 神経発生のｇａｂａ受容体媒介調節 |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US7842713B2 (en) * | 2006-04-20 | 2010-11-30 | Pfizer Inc | Fused phenyl amido heterocyclic compounds |
| CA2651862A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| EP2382975A3 (de) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenese mittels Angiotensin-Modulation |
| KR20090064418A (ko) | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| EP2344458A1 (de) | 2008-09-11 | 2011-07-20 | Pfizer Inc. | Heteroarylamidderivate und ihre verwendung als glucokinase-aktivatoren |
| AR074760A1 (es) | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| DK2406253T3 (da) * | 2009-03-11 | 2013-08-12 | Pfizer | Benzofuranylderivater anvendt som glucokinase-inhibitorer |
| RU2446143C2 (ru) * | 2010-05-19 | 2012-03-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) | Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот |
| JP5746334B2 (ja) * | 2010-06-16 | 2015-07-08 | シマベイ セラピューティクス， インコーポレーテッド | Ｇｐｒ１２０受容体作動薬及びその使用 |
| US8299117B2 (en) | 2010-06-16 | 2012-10-30 | Metabolex Inc. | GPR120 receptor agonists and uses thereof |
| US20150119399A1 (en) | 2012-01-10 | 2015-04-30 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| US11390614B2 (en) | 2017-11-10 | 2022-07-19 | Jiangsu Hengrui Medicine Co., Ltd. | Method for preparing benzofuran derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2137754C1 (ru) * | 1993-07-02 | 1999-09-20 | Бик Гульден Ломберг Хемише Фабрик ГмбХ | Фторалкоксизамещенные бензамиды, способ их получения и фармацевтическая композиция на их основе |
| AU702346B2 (en) * | 1994-07-22 | 1999-02-18 | Altana Pharma Ag | Dihydrobenzofuranes |
| AU705690B2 (en) * | 1995-05-19 | 1999-05-27 | Kyowa Hakko Kogyo Co. Ltd. | Oxygen-containing heterocyclic compounds |
| ATE215540T1 (de) * | 1995-12-05 | 2002-04-15 | Darwin Discovery Ltd | Benzofuran-carboxamide und -sulfonamide |
| PL329912A1 (en) * | 1996-05-20 | 1999-04-26 | Darwin Discovery Ltd | Benzofurane carboxyamides and their therapeutic applications |
-
1997
- 1997-08-13 AU AU44545/97A patent/AU4454597A/en not_active Abandoned
- 1997-08-13 DE DE69717827T patent/DE69717827T2/de not_active Expired - Lifetime
- 1997-08-13 PT PT97942858T patent/PT923568E/pt unknown
- 1997-08-13 AT AT97942858T patent/ATE229516T1/de not_active IP Right Cessation
- 1997-08-13 EP EP97942858A patent/EP0923568B9/de not_active Expired - Lifetime
- 1997-08-13 DK DK97942858T patent/DK0923568T5/da active
- 1997-08-13 ES ES97942858T patent/ES2188983T4/es not_active Expired - Lifetime
- 1997-08-13 JP JP51035698A patent/JP4309475B2/ja not_active Expired - Fee Related
- 1997-08-13 US US09/147,640 patent/US6211203B1/en not_active Expired - Lifetime
- 1997-08-13 WO PCT/EP1997/004398 patent/WO1998007715A1/de not_active Ceased
-
2004
- 2004-06-08 CY CY0400046A patent/CY2458B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0923568T3 (da) | 2003-04-07 |
| JP4309475B2 (ja) | 2009-08-05 |
| CY2458B1 (en) | 2005-06-03 |
| EP0923568A1 (de) | 1999-06-23 |
| DK0923568T5 (da) | 2003-11-03 |
| AU4454597A (en) | 1998-03-06 |
| EP0923568B1 (de) | 2002-12-11 |
| US6211203B1 (en) | 2001-04-03 |
| ES2188983T4 (es) | 2004-06-01 |
| ES2188983T3 (es) | 2003-07-01 |
| PT923568E (pt) | 2003-04-30 |
| DE69717827D1 (de) | 2003-01-23 |
| EP0923568B9 (de) | 2003-08-13 |
| DE69717827T2 (de) | 2003-09-04 |
| WO1998007715A9 (de) | 1999-04-29 |
| JP2000516932A (ja) | 2000-12-19 |
| WO1998007715A1 (de) | 1998-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0923568 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |