ATE221879T1 - Kristalline paclitaxel hydrate - Google Patents
Kristalline paclitaxel hydrateInfo
- Publication number
- ATE221879T1 ATE221879T1 AT95119595T AT95119595T ATE221879T1 AT E221879 T1 ATE221879 T1 AT E221879T1 AT 95119595 T AT95119595 T AT 95119595T AT 95119595 T AT95119595 T AT 95119595T AT E221879 T1 ATE221879 T1 AT E221879T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrates
- crystalline paclitaxel
- paclitaxel
- pseudopolymorph
- crystalline
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 2
- 229960001592 paclitaxel Drugs 0.000 title abstract 2
- -1 PACLITAXEL HYDRATES Chemical class 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35512594A | 1994-12-13 | 1994-12-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE221879T1 true ATE221879T1 (de) | 2002-08-15 |
Family
ID=23396320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95119595T ATE221879T1 (de) | 1994-12-13 | 1995-12-12 | Kristalline paclitaxel hydrate |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0717041B2 (de) |
| JP (1) | JPH08208636A (de) |
| AT (1) | ATE221879T1 (de) |
| AU (1) | AU699542B2 (de) |
| CA (1) | CA2163837C (de) |
| DE (1) | DE69527696T3 (de) |
| DK (1) | DK0717041T3 (de) |
| ES (1) | ES2181744T5 (de) |
| PT (1) | PT717041E (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| FR2729666A1 (fr) * | 1995-01-25 | 1996-07-26 | Rhone Poulenc Rorer Sa | Procede de preparation du trihydrate du (2r, 3s)- benzoylamino-2-hydroxy-3-phenylpropionate de 4,10-diacetoxy- 2alpha-benzoyloxy-5beta,20-epoxy-1,7beta-dihydroxy-9-oxo- tax-11-en-13alpha-yle |
| US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US6515016B2 (en) * | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
| JP2001521503A (ja) † | 1997-03-31 | 2001-11-06 | ネオルックス コーポレイション | 血管平滑筋細胞の治療的阻害物質 |
| HUP9701945A3 (en) * | 1997-11-10 | 2000-04-28 | Hexal Ag | Pharmaceutical composition for injection containing cyclodextrin and taxoids |
| US6136989A (en) * | 1998-12-30 | 2000-10-24 | Phytogen Life Sciences, Incorporated | Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material |
| PL203300B1 (pl) * | 2000-10-31 | 2009-09-30 | Akad Medyczna | Stabilna postać farmaceutyczna leku przeciwnowotworowego oraz sposób wytwarzania stabilnej postaci farmaceutycznej leku przeciwnowotworowego |
| DE10115740A1 (de) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| HUP0600533A2 (en) | 2001-11-30 | 2006-11-28 | Bristol Myers Squibb Co | Paclitaxel solvates |
| AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
| HRP20020614A2 (en) * | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
| US7919108B2 (en) | 2006-03-10 | 2011-04-05 | Cook Incorporated | Taxane coatings for implantable medical devices |
| US7875284B2 (en) | 2006-03-10 | 2011-01-25 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
| EP2043704B2 (de) | 2006-06-30 | 2017-04-19 | Cook Medical Technologies LLC | Verfahren zur herstellung und modifizierung von taxan-beschichtungen für implantierbare medizinische vorrichtungen |
| EP2269664B1 (de) | 2007-01-21 | 2012-08-22 | Hemoteq AG | Medizinprodukt zur Behandlung von Verschlüssen von Körperdurchgängen und zur Prävention drohender Wiederverschlüsse |
| US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
| FR2926551A1 (fr) * | 2008-01-17 | 2009-07-24 | Aventis Pharma Sa | Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation |
| EP2944332B1 (de) | 2009-07-10 | 2016-08-17 | Boston Scientific Scimed, Inc. | Verwendung von nanokristallen für einen wirkstofffreisetzungsballon |
| JP5933434B2 (ja) | 2009-07-17 | 2016-06-08 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 薬剤送達バルーンの製造方法 |
| US8889211B2 (en) | 2010-09-02 | 2014-11-18 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
| WO2013022458A1 (en) | 2011-08-05 | 2013-02-14 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
| US9056152B2 (en) | 2011-08-25 | 2015-06-16 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
| US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
| CN111803698B (zh) * | 2014-02-14 | 2022-05-27 | 波士顿科学国际有限公司 | 具有治疗剂释放的快速降解栓塞颗粒 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) † | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US4960790A (en) † | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| US5380916A (en) † | 1990-11-02 | 1995-01-10 | University Of Florida | Method for the isolation and purification of taxane derivatives |
| TW467896B (en) † | 1993-03-19 | 2001-12-11 | Bristol Myers Squibb Co | Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes |
-
1995
- 1995-11-27 CA CA002163837A patent/CA2163837C/en not_active Expired - Fee Related
- 1995-12-12 EP EP95119595A patent/EP0717041B2/de not_active Expired - Lifetime
- 1995-12-12 AT AT95119595T patent/ATE221879T1/de not_active IP Right Cessation
- 1995-12-12 PT PT95119595T patent/PT717041E/pt unknown
- 1995-12-12 DE DE69527696T patent/DE69527696T3/de not_active Expired - Fee Related
- 1995-12-12 AU AU40355/95A patent/AU699542B2/en not_active Ceased
- 1995-12-12 ES ES95119595T patent/ES2181744T5/es not_active Expired - Lifetime
- 1995-12-12 DK DK95119595T patent/DK0717041T3/da active
- 1995-12-13 JP JP7324202A patent/JPH08208636A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2163837A1 (en) | 1996-06-14 |
| JPH08208636A (ja) | 1996-08-13 |
| EP0717041B2 (de) | 2007-08-15 |
| DE69527696D1 (de) | 2002-09-12 |
| EP0717041B1 (de) | 2002-08-07 |
| PT717041E (pt) | 2002-11-29 |
| CA2163837C (en) | 1999-07-20 |
| AU699542B2 (en) | 1998-12-03 |
| EP0717041A1 (de) | 1996-06-19 |
| ES2181744T5 (es) | 2008-03-01 |
| ES2181744T3 (es) | 2003-03-01 |
| DK0717041T3 (da) | 2002-11-25 |
| AU4035595A (en) | 1996-06-20 |
| DE69527696T3 (de) | 2008-04-03 |
| DE69527696T2 (de) | 2003-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0717041 Country of ref document: EP |
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| UEP | Publication of translation of european patent specification |
Ref document number: 0717041 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |