ATE220665T1 - Azetidincarboxamidderivate zur behandlung von zns-erkrankungen - Google Patents

Azetidincarboxamidderivate zur behandlung von zns-erkrankungen

Info

Publication number: ATE220665T1
Authority: AT; Austria
Prior art keywords: treatment; carboxamide derivatives; cns diseases; azetidine carboxamide; azetidine
Prior art date: 1998-01-23

Application number

AT99901781T

Other languages

English (en)

Inventor

Robin Gerald Shepherd

David Reginald Adams

Jon Bentley

Corinna Dagmar Bodkin

Ian Anthony Cliffe

James Edward Paul Davidson

Howard Langham Mansell

Nathaniel Julius Monck

Original Assignee

Vernalis Res Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-23

Filing date

1999-01-22

Publication date

2002-08-15

1998-01-23 Priority claimed from GBGB9801499.6A external-priority patent/GB9801499D0/en

1998-11-06 Priority claimed from GBGB9824458.5A external-priority patent/GB9824458D0/en

1999-01-22 Application filed by Vernalis Res Ltd filed Critical Vernalis Res Ltd

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE220665T1 publication Critical patent/ATE220665T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)

AT99901781T 1998-01-23 1999-01-22 Azetidincarboxamidderivate zur behandlung von zns-erkrankungen ATE220665T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9801499.6A GB9801499D0 (en)	1998-01-23	1998-01-23	Chemical compounds iii
GBGB9824458.5A GB9824458D0 (en)	1998-11-06	1998-11-06	Chemical compounds II
PCT/GB1999/000223 WO1999037613A1 (en)	1998-01-23	1999-01-22	Azetidinecarboxamide derivatives for treating cns disorders

Publications (1)

Publication Number	Publication Date
ATE220665T1 true ATE220665T1 (de)	2002-08-15

Family

ID=26313009

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99901781T ATE220665T1 (de)	1998-01-23	1999-01-22	Azetidincarboxamidderivate zur behandlung von zns-erkrankungen

Country Status (10)

Country	Link
US (1)	US6831078B1 (de)
EP (1)	EP1049670B1 (de)
JP (1)	JP4542264B2 (de)
AT (1)	ATE220665T1 (de)
AU (1)	AU2178099A (de)
DE (1)	DE69902142T2 (de)
DK (1)	DK1049670T3 (de)
ES (1)	ES2181387T3 (de)
PT (1)	PT1049670E (de)
WO (1)	WO1999037613A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9917384D0 (en) *	1999-07-23	1999-09-22	Cerebrus Ltd	Chemical compounds-III
CA2744307A1 (en) *	2008-11-24	2010-05-27	Nsab, Filial Af Neurosearch Sweden Ab, Sverige	Novel 3-phenyl-azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
CN115650893B (zh) *	2022-10-24	2024-08-06	南通华祥医药科技有限公司	一种1-二苯甲基氮杂环丁烷-3-酮的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB872447A (en) *	1958-12-23	1961-07-12	Lepetit Spa	1-carbamyl-3-substituted azetidines
US4226861A (en)	1978-04-18	1980-10-07	A. H. Robins Company, Inc.	N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
IL68699A (en)	1982-08-19	1986-08-31	Robins Co Inc A H	3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them
US4505907A (en) *	1982-09-02	1985-03-19	A. H. Robins Company, Inc.	N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
US4956359A (en) *	1985-02-28	1990-09-11	A. H. Robins Company, Inc.	3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics
FI87559C (fi) *	1985-02-28	1993-01-25	Robins Co Inc A H	Foerfarande foer framstaellning av aktiva 3-fenyloxiazetidinkarboxamider

1999
- 1999-01-22 DE DE69902142T patent/DE69902142T2/de not_active Expired - Lifetime
- 1999-01-22 DK DK99901781T patent/DK1049670T3/da active
- 1999-01-22 AT AT99901781T patent/ATE220665T1/de not_active IP Right Cessation
- 1999-01-22 EP EP99901781A patent/EP1049670B1/de not_active Expired - Lifetime
- 1999-01-22 US US09/600,631 patent/US6831078B1/en not_active Expired - Lifetime
- 1999-01-22 ES ES99901781T patent/ES2181387T3/es not_active Expired - Lifetime
- 1999-01-22 WO PCT/GB1999/000223 patent/WO1999037613A1/en active IP Right Grant
- 1999-01-22 PT PT99901781T patent/PT1049670E/pt unknown
- 1999-01-22 JP JP2000528537A patent/JP4542264B2/ja not_active Expired - Lifetime
- 1999-01-22 AU AU21780/99A patent/AU2178099A/en not_active Abandoned

Also Published As

Publication number	Publication date
WO1999037613A1 (en)	1999-07-29
US6831078B1 (en)	2004-12-14
EP1049670B1 (de)	2002-07-17
AU2178099A (en)	1999-08-09
PT1049670E (pt)	2002-12-31
DK1049670T3 (da)	2002-11-11
JP4542264B2 (ja)	2010-09-08
ES2181387T3 (es)	2003-02-16
DE69902142D1 (de)	2002-08-22
JP2002501046A (ja)	2002-01-15
DE69902142T2 (de)	2003-01-09
EP1049670A1 (de)	2000-11-08

Publication	Publication Date	Title
DE69411424D1 (de)	1998-08-13	Zur Behandlung von Erkrankungen des Zentralnervensystems verwendbare Benzimidazole
SE0104332D0 (sv)	2001-12-19	Therapeutic agents
MY135841A (en)	2008-07-31	Novel benzodioxoles
DE69529141D1 (de)	2003-01-23	5-HT1F Agonisten zur Behandlung von Migräne
GB0225475D0 (en)	2002-12-11	Therapeutic agents
AU2001273094A1 (en)	2002-01-14	Compounds to treat alzheimer's disease
SG128491A1 (en)	2007-01-30	Heterocyclic sulfonamide inhibitors of beta amyloid production
GB0005251D0 (en)	2000-04-26	Therapeutic compounds
DE60025848D1 (en)	2006-04-13	Pyrimidin-derivate als selective inhibitoren von cox-2
DK0765320T3 (da)	2001-11-26	Benzimidazolonderivater med central dopaminerg aktivitet
DE69911373D1 (de)	2003-10-23	Azetidincarboxamidderivate zur behandlung von zns-erkrankungen
DE69828197D1 (de)	2005-01-20	Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut
SE9702716D0 (sv)	1997-07-15	Substituted phenylazacycloalkanes in the treatment of cognitive disorders
DE69902142D1 (de)	2002-08-22	Azetidincarboxamidderivate zur behandlung von zns-erkrankungen
DK0804186T3 (da)	2002-06-17	Indolditerpenalkaloidforbindelser
ATE264840T1 (de)	2004-05-15	Azetidincarboxamid-derivate zur behandlung von zns störungen
IL156768A0 (en)	2004-02-08	Process for preparing (+/-) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine
AU640590B2 (en)	1993-08-26	3-(1h-indazol-3-yl)-4-pyridinamines
ES2193047T3 (es)	2003-11-01	(3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas.
DE69619088D1 (de)	2002-03-21	Quinoxalin-Derivate zur Behandlung von Tinnitus
ATE283269T1 (de)	2004-12-15	5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems

Legal Events

Date	Code	Title	Description
2002-11-15	UEP	Publication of translation of european patent specification
2010-10-15	REN	Ceased due to non-payment of the annual fee