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ATE220110T1 - Assays und reaganzien zur identifizierung von fungiziden wirkstoffen und ihre verwendungen - Google Patents

Assays und reaganzien zur identifizierung von fungiziden wirkstoffen und ihre verwendungen

Info

Publication number
ATE220110T1
ATE220110T1 AT97921143T AT97921143T ATE220110T1 AT E220110 T1 ATE220110 T1 AT E220110T1 AT 97921143 T AT97921143 T AT 97921143T AT 97921143 T AT97921143 T AT 97921143T AT E220110 T1 ATE220110 T1 AT E220110T1
Authority
AT
Austria
Prior art keywords
reagants
assay
active ingredients
fungicidal active
relates
Prior art date
Application number
AT97921143T
Other languages
English (en)
Inventor
Vivian Berlin
David E Levin
Yoshikazu Ohya
Original Assignee
Mitotix Inc
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/631,319 external-priority patent/US6117641A/en
Application filed by Mitotix Inc, Univ Johns Hopkins filed Critical Mitotix Inc
Application granted granted Critical
Publication of ATE220110T1 publication Critical patent/ATE220110T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/40—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • G01N2333/40—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Candida
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/91091—Glycosyltransferases (2.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/9116—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • G01N2333/91165—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5) general (2.5.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97921143T 1996-04-11 1997-04-11 Assays und reaganzien zur identifizierung von fungiziden wirkstoffen und ihre verwendungen ATE220110T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/631,319 US6117641A (en) 1996-04-11 1996-04-11 Assays and reagents for identifying anti-fungal agents and uses related thereto
US08/771,212 US6455281B1 (en) 1996-04-11 1996-12-20 Nucleic acids for identifying anti-fungal agents, and uses related thereto
PCT/US1997/005987 WO1997038293A2 (en) 1996-04-11 1997-04-11 Assays and reagents for identifying anti-fungal agents, and uses related thereto

Publications (1)

Publication Number Publication Date
ATE220110T1 true ATE220110T1 (de) 2002-07-15

Family

ID=27091358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97921143T ATE220110T1 (de) 1996-04-11 1997-04-11 Assays und reaganzien zur identifizierung von fungiziden wirkstoffen und ihre verwendungen

Country Status (9)

Country Link
US (2) US6277564B1 (de)
EP (1) EP0892854B1 (de)
JP (1) JP2001513622A (de)
KR (1) KR20000005397A (de)
AT (1) ATE220110T1 (de)
AU (1) AU717165B2 (de)
CA (1) CA2251593A1 (de)
DE (1) DE69713759T2 (de)
WO (1) WO1997038293A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117641A (en) 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
AU717165B2 (en) 1996-04-11 2000-03-16 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
WO1998018927A1 (en) * 1996-10-30 1998-05-07 National Research Council Of Canada Candida albicans proteins associated with virulence and hyphal formation and uses thereof
JPH11103862A (ja) * 1997-10-01 1999-04-20 Takara Shuzo Co Ltd 抗原タンパク質及び該タンパク質をコードする核酸
WO1999046286A2 (en) * 1998-03-13 1999-09-16 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US6423519B1 (en) 1998-07-15 2002-07-23 Gpc Biotech Inc. Compositions and methods for inhibiting fungal growth
US6720139B1 (en) * 1999-01-27 2004-04-13 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation in Escherichia coli
WO2001034810A2 (en) * 1999-11-09 2001-05-17 Elitra Pharmaceuticals, Inc. Genes essential for microbial proliferation
US6783985B1 (en) 2000-02-18 2004-08-31 Elitra Pharmaceuticals Inc. Gene disruption methodologies for drug target discovery
US20030180953A1 (en) * 2000-12-29 2003-09-25 Elitra Pharmaceuticals, Inc. Gene disruption methodologies for drug target discovery
CA2445179A1 (en) * 2001-04-23 2002-10-31 Elitra Pharmaceuticals, Inc. Identification of essential genes of aspegillus fumigatus and methods of use
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
US20030170694A1 (en) * 2001-12-21 2003-09-11 Daniel Wall Stabilized nucleic acids in gene and drug discovery and methods of use
US20050182250A1 (en) * 2002-07-10 2005-08-18 Stratagene Humanized renilla reniformis green fluorescent protein as a scaffold
KR100914749B1 (ko) 2002-12-31 2009-08-31 엘지디스플레이 주식회사 구동회로를 포함하는 반사형 액정 표시 장치

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59212439A (ja) 1983-05-19 1984-12-01 Taisho Pharmaceut Co Ltd スチレン誘導体
JP2971894B2 (ja) * 1988-08-10 1999-11-08 武田薬品工業株式会社 Ｃ―キナーゼの酵母による製造法
AU7556991A (en) 1990-03-15 1991-10-10 Board Of Regents, The University Of Texas System Recombinant beta -1,4 glucan synthase proteins
US5202456A (en) 1991-04-15 1993-04-13 The President And Fellows Of Harvard College Compounds for inhibition of protein methylation
IL99628A (en) 1991-10-02 2004-07-25 Yissum Res Dev Co Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them
DE69205657T2 (de) 1991-10-11 1996-06-13 Squibb & Sons Inc Verwendung von Biphosphonaten zur Herstellung eines Arzneimittels zur Blockierung neoplastischer Zelltransformationen die durch Ras-Oncogene verursacht werden.
US5789541A (en) 1992-07-14 1998-08-04 President And Fellows Of Harvard College Compounds for inhibition of proteolysis
GB9226065D0 (en) 1992-12-14 1993-02-10 Ici Plc Peptides
US5602184A (en) 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
CA2118985A1 (en) 1993-04-02 1994-10-03 Dinesh V. Patel Heterocyclic inhibitors of farnesyl protein transferase
EP0621342A1 (de) 1993-04-20 1994-10-26 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Reagenz und Testsatz zum Nachweis oder zur Hemmung von isoprenylierender Aktivität
EP0763537A3 (de) 1993-05-14 1997-10-22 Genentech Inc Nichtpeptide Farnesyltransferas Inhibitoren
AU681119B2 (en) 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
US5705686A (en) 1993-05-18 1998-01-06 University Of Pittsburgh Inhibition of farnesyl transferase
US5602098A (en) 1993-05-18 1997-02-11 University Of Pittsburgh Inhibition of farnesyltransferase
ES2210263T3 (es) * 1993-10-12 2004-07-01 MERCK & CO., INC. Adn que codifica subunidades de 1,3,-beta-d glucano sintasa.
US5721236A (en) 1993-10-15 1998-02-24 Schering Corporation Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
IL111235A (en) 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
WO1995011917A1 (en) 1993-10-25 1995-05-04 Parke, Davis & Company Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
IL107587A (en) 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
US5539132A (en) 1994-01-24 1996-07-23 Johns Hopkins University Cerulenin compounds for fatty acid synthesis inhibition
US5470832A (en) 1994-01-31 1995-11-28 Merck & Co., Inc. Inhibitors of geranylgeranyl-protein transferase
WO1995025086A1 (en) 1994-03-15 1995-09-21 Eisai Co., Ltd. Isoprenyl transferase inhibitors
US5580979A (en) 1994-03-15 1996-12-03 Trustees Of Tufts University Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
CA2143588A1 (en) 1994-03-24 1995-09-25 Rajeev Bhide Inhibitors of farnesyl protein transferase
US5510510A (en) 1994-05-10 1996-04-23 Bristol-Meyers Squibb Company Inhibitors of farnesyl protein transferase
US5541181A (en) 1994-05-26 1996-07-30 Bristol-Myers Squibb Company Compound produced by a strain of micromonospora
US5484724A (en) 1994-05-26 1996-01-16 Merck & Co., Inc. DNA encoding GLSI
US5574025A (en) 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
US5606043A (en) 1994-11-03 1997-02-25 The Regents Of The University Of California Methods for the diagnosis of glaucoma
WO1996017623A1 (en) 1994-12-09 1996-06-13 Banyu Pharmaceutical Co., Ltd. Anti-aids drug
AU4915796A (en) 1995-01-12 1996-07-31 University Of Pittsburgh Inhibitors of prenyl transferases
US5684013A (en) 1995-03-24 1997-11-04 Schering Corporation Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5624936A (en) 1995-03-29 1997-04-29 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
IL117797A0 (en) 1995-04-07 1996-08-04 Pharmacopeia Inc Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
EP0745628B1 (de) 1995-05-31 2002-04-03 Shell Internationale Researchmaatschappij B.V. Copolyester Zusammensetzung
US5723686A (en) 1995-08-03 1998-03-03 Phillips Petroleum Company Recycle of alcohol in a combined hydroisomerization and etherification process
GB2306646A (en) 1995-10-30 1997-05-07 Merck & Co Inc Assay for compounds which inhibit ras oncogene activity involving farnesyl-protein transferase
AU7597596A (en) 1995-11-06 1997-05-29 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
EP0862435A4 (de) 1995-11-22 1999-02-03 Merck & Co Inc Inhibitoren der farnesyl-protein-transferase
IT1276162B1 (it) 1995-11-23 1997-10-27 Baldacci Lab Spa Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche
EP0879279A4 (de) 1996-02-06 2000-07-12 Lilly Co Eli Diabetestherapie
US6011029A (en) 1996-02-26 2000-01-04 Bristol-Myers Squibb Company Inhibitors of farnesyl protein transferase
AU717165B2 (en) 1996-04-11 2000-03-16 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
CA2251955A1 (en) 1996-04-18 1997-10-23 Nancy E. Kohl A method of treating cancer

Also Published As

Publication number Publication date
AU2726597A (en) 1997-10-29
CA2251593A1 (en) 1997-10-16
US6277564B1 (en) 2001-08-21
DE69713759D1 (de) 2002-08-08
KR20000005397A (ko) 2000-01-25
WO1997038293A3 (en) 1997-12-04
EP0892854A2 (de) 1999-01-27
AU717165B2 (en) 2000-03-16
EP0892854B1 (de) 2002-07-03
JP2001513622A (ja) 2001-09-04
DE69713759T2 (de) 2003-03-13
US6271197B1 (en) 2001-08-07
WO1997038293A2 (en) 1997-10-16

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