ATE216229T1 - Emulsion zur verabreichung eines sphingolipids und deren verwendung - Google Patents
Emulsion zur verabreichung eines sphingolipids und deren verwendungInfo
- Publication number
- ATE216229T1 ATE216229T1 AT95942970T AT95942970T ATE216229T1 AT E216229 T1 ATE216229 T1 AT E216229T1 AT 95942970 T AT95942970 T AT 95942970T AT 95942970 T AT95942970 T AT 95942970T AT E216229 T1 ATE216229 T1 AT E216229T1
- Authority
- AT
- Austria
- Prior art keywords
- emulsion
- sphingolipid
- administration
- cholesterol
- cationic
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 3
- 150000003408 sphingolipids Chemical class 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- -1 cationic sphingolipid Chemical class 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/351,635 US5635536A (en) | 1994-12-07 | 1994-12-07 | Emulsion suitable for administering a sphingolipid |
PCT/US1995/015687 WO1996017603A1 (en) | 1994-12-07 | 1995-12-01 | Emulsion suitable for administering a sphingolipid and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE216229T1 true ATE216229T1 (de) | 2002-05-15 |
Family
ID=23381694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95942970T ATE216229T1 (de) | 1994-12-07 | 1995-12-01 | Emulsion zur verabreichung eines sphingolipids und deren verwendung |
Country Status (10)
Country | Link |
---|---|
US (2) | US5635536A (de) |
EP (1) | EP0799035B1 (de) |
JP (1) | JPH10510267A (de) |
AT (1) | ATE216229T1 (de) |
AU (1) | AU4414096A (de) |
DE (1) | DE69526450T2 (de) |
DK (1) | DK0799035T3 (de) |
ES (1) | ES2177676T3 (de) |
PT (1) | PT799035E (de) |
WO (1) | WO1996017603A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6720184B1 (en) | 1991-08-05 | 2004-04-13 | Emory University | Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination |
AU692255B2 (en) * | 1995-04-24 | 1998-06-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsifiable formulation producing an oil-in-water emulsion |
US6982142B2 (en) * | 1997-12-01 | 2006-01-03 | John Wayne Cancer Institute | Methods for screening therapeutically effective agents |
WO1999041266A1 (en) | 1998-02-12 | 1999-08-19 | Emory University | Sphingolipid derivatives and their methods of use |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
US6194391B1 (en) | 1998-06-24 | 2001-02-27 | Emory University | 3′-azido-2′,3′-dideoxyuridine administration to treat HIV and related test protocol |
US6352844B1 (en) | 1998-06-29 | 2002-03-05 | Childrens Hospital Los Angeles | Treatment of hyperproliferative disorders |
US6368831B1 (en) | 1998-06-29 | 2002-04-09 | Childrens Hospital Los Angeles | Treatment of hyperproliferative disorders |
WO2000010531A1 (en) | 1998-08-19 | 2000-03-02 | Rtp Pharma Inc. | Injectable aqueous dispersions of propofol |
GB2359747B (en) * | 2000-02-29 | 2002-04-24 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
US7846969B2 (en) * | 2001-12-10 | 2010-12-07 | Kao Corporation | Ceramide emulsions |
ATE331507T1 (de) * | 2003-02-21 | 2006-07-15 | Los Angeles Childrens Hospital | Stabile pharmazeutische zusammensetzung mit safingol und verfahren zu dessen verwendung |
JP2006028109A (ja) * | 2004-07-20 | 2006-02-02 | Kao Corp | 水中油型乳化組成物 |
US8557861B2 (en) | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
WO2011044207A2 (en) * | 2009-10-06 | 2011-04-14 | L'oreal S.A. | Compositions containing a high concentration of polar sphingolipid(s) |
JP6960984B2 (ja) * | 2019-12-26 | 2021-11-05 | 三菱電機株式会社 | 電子装置及びその絶縁部材 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1792410B2 (de) * | 1967-09-01 | 1980-03-13 | Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm | Arzneimittelzubereitung zur intravenösen Injektion |
JPS6030652B2 (ja) * | 1979-05-07 | 1985-07-17 | 株式会社ミドリ十字 | 静脈注射用脂肪乳剤 |
IT1171432B (it) * | 1981-08-03 | 1987-06-10 | Fidia Farmaceutici | Amidi organiche derivate da lipidi azotati utilizzabili come farmaci |
US4937232A (en) * | 1986-09-15 | 1990-06-26 | Duke University | Inhibition of protein kinase C by long-chain bases |
US4816450A (en) * | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
CA2013755C (en) * | 1989-04-05 | 1993-11-30 | Simon Benita | Medicinal emulsions |
US5364632A (en) * | 1989-04-05 | 1994-11-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
US5198470A (en) * | 1989-09-21 | 1993-03-30 | L'oreal | Lipid compounds derived from sphingosines, process for preparing these and their applications, in particular in cosmetics and in the pharmacy of skin conditions |
FR2652002B1 (fr) * | 1989-09-21 | 1991-11-29 | Oreal | Nouveaux composes lipidiques derives des sphingosines, leur procede de preparation et leurs applications, notamment en cosmetique et en dermopharmacie. |
DE4015108A1 (de) * | 1990-05-11 | 1991-11-14 | Leopold Pharma Gmbh | Stabile emulsion zur applikation pharmakologisch aktiver wirkstoffe |
US5149794A (en) * | 1990-11-01 | 1992-09-22 | State Of Oregon | Covalent lipid-drug conjugates for drug targeting |
USH1168H (en) * | 1991-08-21 | 1993-04-06 | The United States Of America As Represented By The Secretary Of The Navy | Inhibitors of protein kinase C activity as protectors against septic shock and reducers of ARDS |
-
1994
- 1994-12-07 US US08/351,635 patent/US5635536A/en not_active Expired - Fee Related
-
1995
- 1995-12-01 WO PCT/US1995/015687 patent/WO1996017603A1/en active IP Right Grant
- 1995-12-01 PT PT95942970T patent/PT799035E/pt unknown
- 1995-12-01 DE DE69526450T patent/DE69526450T2/de not_active Expired - Fee Related
- 1995-12-01 AU AU44140/96A patent/AU4414096A/en not_active Abandoned
- 1995-12-01 JP JP8517678A patent/JPH10510267A/ja not_active Ceased
- 1995-12-01 DK DK95942970T patent/DK0799035T3/da active
- 1995-12-01 AT AT95942970T patent/ATE216229T1/de not_active IP Right Cessation
- 1995-12-01 EP EP95942970A patent/EP0799035B1/de not_active Expired - Lifetime
- 1995-12-01 ES ES95942970T patent/ES2177676T3/es not_active Expired - Lifetime
-
1996
- 1996-07-16 US US08/680,993 patent/US5677341A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0799035A4 (de) | 1999-06-09 |
DK0799035T3 (da) | 2002-07-22 |
EP0799035B1 (de) | 2002-04-17 |
EP0799035A1 (de) | 1997-10-08 |
PT799035E (pt) | 2002-09-30 |
US5677341A (en) | 1997-10-14 |
ES2177676T3 (es) | 2002-12-16 |
US5635536A (en) | 1997-06-03 |
AU4414096A (en) | 1996-06-26 |
WO1996017603A1 (en) | 1996-06-13 |
DE69526450D1 (de) | 2002-05-23 |
DE69526450T2 (de) | 2002-11-14 |
JPH10510267A (ja) | 1998-10-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE216229T1 (de) | Emulsion zur verabreichung eines sphingolipids und deren verwendung | |
ATE149828T1 (de) | Arzneistofformulierung zur parenteralen anwendung | |
PT92131A (pt) | Processo para a preparacao de meios para aplicacao transdermicacontendo gestodeno | |
ATE232720T1 (de) | Adjuvans für impfstoff | |
ATE333867T1 (de) | Emulgierte arzneistoffabgabesysteme | |
DE59604603D1 (de) | Arzneiform zur abgabe von wirkstoffen an wunden | |
BR9504781A (pt) | Composição cosmética ou dematológica processo de preparação de uma composição e emulsão do tipo óleo em agua | |
FI971776A0 (fi) | Yhdisteet ja koostumukset aktiivisten aineiden antamiseksi | |
BR9510452A (pt) | Composição farmacêutica e aquosa estéril para a administração parenteral processos para limitar o potencial de crescimento microbiano em composição farmacêutica estéril para a administração parenteral para produzir anestesia em um animal de sangue quente e para aperfeiçoar o tempo de administração e/ou o tempo entre as trocas de conjuntos | |
ES2081488T3 (es) | Uso de fosfolipido en la fabricacion de un medicamento topico para modificar los niveles de colesterol serico. | |
FI935851A0 (fi) | Antiallergisk sammansaettning foer oftalmiskt eller nasalt bruk | |
ES2136315T3 (es) | Uso de fluorocarbonos liquidos para facilitar la aportacion de medicamentos a los pulmones. | |
DE69121561D1 (de) | Verwendung von 3-guanidinopropionsäure zur herstellung eines medikaments zur behandlung und prävention von fettsucht | |
BR9809492A (pt) | Composição farmacêutica aquosa injetável, e, processo para a preparação da mesma | |
ATE223205T1 (de) | Verfahren zur herstellung von liposomen, die hydrophobische artzneistoffe enthalten | |
BR0211008A (pt) | Combinação de ingrediente ativo, uso de uma combinação de ingrediente ativo e método para a terapia farmacológia de uma substância que causa dependência ou que seja intoxicante | |
ES2090712T3 (es) | Medicamento agudo que contiene ibuprofeno y su uso. | |
ES2090703T3 (es) | Medicamento agudo que contiene flurbiprofeno y su empleo. | |
ATE132758T1 (de) | Anwendung von dispersionen von magneto-ionischen partikeln in mri-kontrast-mitteln | |
ATE221919T1 (de) | In flüssiger form stabiler thiolaktivator | |
ATE374594T1 (de) | Zusammensetzung in form einer öl-in-wasser emulsion und deren kosmetische verwendungen | |
BR0213434A (pt) | Método para evitar demência em um paciente, e, uso de rosuvastatina ou seu sal farmaceuticamente aceitável | |
ATE131031T1 (de) | Zubereitung zur topischen anwendung. | |
GB9902527D0 (en) | Compositions | |
MX9801902A (es) | Composicion dermatologica antiseptica y procedimiento para su fabricacion. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |