ATE21509T1 - Beta-lactam-essigsaeure-derivate, verfahren zu deren herstellung und deren verwendung als zwischenverbindungen fuer 1-azabicyclo(3.2.0)hept- 2-en-antibiotika. - Google Patents
Beta-lactam-essigsaeure-derivate, verfahren zu deren herstellung und deren verwendung als zwischenverbindungen fuer 1-azabicyclo(3.2.0)hept- 2-en-antibiotika.Info
- Publication number
- ATE21509T1 ATE21509T1 AT82101463T AT82101463T ATE21509T1 AT E21509 T1 ATE21509 T1 AT E21509T1 AT 82101463 T AT82101463 T AT 82101463T AT 82101463 T AT82101463 T AT 82101463T AT E21509 T1 ATE21509 T1 AT E21509T1
- Authority
- AT
- Austria
- Prior art keywords
- antibiotics
- acid derivatives
- beta
- azabicyclo
- hept
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8107865 | 1981-03-12 | ||
| EP82101463A EP0060416B1 (de) | 1981-03-12 | 1982-02-26 | Beta-Lactam-essigsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Zwischenverbindungen für 1-Azabicyclo(3.2.0)hept-2-en-Antibiotika |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE21509T1 true ATE21509T1 (de) | 1986-09-15 |
Family
ID=10520350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82101463T ATE21509T1 (de) | 1981-03-12 | 1982-02-26 | Beta-lactam-essigsaeure-derivate, verfahren zu deren herstellung und deren verwendung als zwischenverbindungen fuer 1-azabicyclo(3.2.0)hept- 2-en-antibiotika. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4576746A (de) |
| EP (1) | EP0060416B1 (de) |
| JP (1) | JPS57159761A (de) |
| KR (1) | KR880001847B1 (de) |
| AT (1) | ATE21509T1 (de) |
| AU (1) | AU548727B2 (de) |
| CA (1) | CA1185244A (de) |
| DE (1) | DE3272660D1 (de) |
| DK (1) | DK103982A (de) |
| ES (2) | ES510336A0 (de) |
| IE (1) | IE52609B1 (de) |
| IL (1) | IL65232A (de) |
| PH (1) | PH23415A (de) |
| ZA (1) | ZA821252B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU187424B (en) * | 1982-11-05 | 1986-01-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing new azetidinyl-acetic acids |
| JPS60224672A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | β−ラクタム誘導体の製造法 |
| JPS62209079A (ja) * | 1986-03-11 | 1987-09-14 | Sanraku Inc | 二置換アミノカルバペナム類 |
| JP2618271B2 (ja) * | 1989-04-26 | 1997-06-11 | 日本化薬株式会社 | モノｐ―ニトロベンジルマロネートマグネシウム塩の結晶変態及びその製法 |
| RU2130927C1 (ru) * | 1992-09-18 | 1999-05-27 | Мерк Энд Ко., Инк. | Способы получения промежуточных соединений бета-метилкарбапенемов, промежуточные соединения |
| US5516934A (en) * | 1994-08-05 | 1996-05-14 | Nippon Kayaku Kabushiki Kaisha | Process for producing mono-P-nitrobenzyl malonate |
| US20040148868A1 (en) * | 2003-02-05 | 2004-08-05 | 3M Innovative Properties Company | Methods of making ceramics |
| WO2006061854A2 (en) * | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | CONTROL OF pH BY DIRECT ADDITION OF CARBONATES AND BICARBONATES DURING CONCENTRATION OF ORGANIC SOLVENT EXTRACTS OF 6- ACETYL- 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE AND 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE |
| NZ599059A (en) | 2009-09-03 | 2014-05-30 | Pfizer Vaccines Llc | Pcsk9 vaccine |
| WO2011048583A1 (en) * | 2009-10-23 | 2011-04-28 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| CN103483202B (zh) * | 2013-06-26 | 2015-01-21 | 华北水利水电大学 | 一种对硝基苄醇丙二酸单酯镁的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1570278A (en) * | 1975-10-06 | 1980-06-25 | Fujisawa Pharmaceutical Co | O-substituted-2-azetidinone derivatives and the preparation thereof |
| US4138400A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | Omega-alkoxy derivatives of lactams |
| GB1584762A (en) * | 1977-04-01 | 1981-02-18 | Beecham Group Ltd | Azabicycloheptenes |
| DK165280A (da) * | 1979-04-19 | 1980-10-20 | Merck & Co Inc | Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden |
| US4290947A (en) * | 1979-04-27 | 1981-09-22 | Merck & Co., Inc. | Process for the preparation of thienamycin and intermediates |
| US4262010A (en) * | 1979-12-03 | 1981-04-14 | Merck & Co., Inc. | 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4312871A (en) * | 1979-12-03 | 1982-01-26 | Merck & Co., Inc. | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4269772A (en) * | 1980-01-14 | 1981-05-26 | Merck & Co., Inc. | Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline |
| US4282148A (en) * | 1980-01-14 | 1981-08-04 | Merck & Co., Inc. | Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid |
| US4287123A (en) * | 1980-01-14 | 1981-09-01 | Merck & Co., Inc. | Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate |
-
1982
- 1982-02-24 AU AU80765/82A patent/AU548727B2/en not_active Ceased
- 1982-02-25 ZA ZA821252A patent/ZA821252B/xx unknown
- 1982-02-26 AT AT82101463T patent/ATE21509T1/de not_active IP Right Cessation
- 1982-02-26 EP EP82101463A patent/EP0060416B1/de not_active Expired
- 1982-02-26 DE DE8282101463T patent/DE3272660D1/de not_active Expired
- 1982-03-04 PH PH26950A patent/PH23415A/en unknown
- 1982-03-04 US US06/354,572 patent/US4576746A/en not_active Expired - Fee Related
- 1982-03-10 DK DK103982A patent/DK103982A/da not_active Application Discontinuation
- 1982-03-11 IE IE554/82A patent/IE52609B1/en unknown
- 1982-03-11 ES ES510336A patent/ES510336A0/es active Granted
- 1982-03-11 CA CA000398140A patent/CA1185244A/en not_active Expired
- 1982-03-11 KR KR8201103A patent/KR880001847B1/ko active
- 1982-03-12 IL IL65232A patent/IL65232A/xx unknown
- 1982-03-12 JP JP57039284A patent/JPS57159761A/ja active Pending
- 1982-10-25 ES ES516808A patent/ES8402590A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU548727B2 (en) | 1986-01-02 |
| KR880001847B1 (ko) | 1988-09-22 |
| ZA821252B (en) | 1983-01-26 |
| ES516808A0 (es) | 1984-02-01 |
| IL65232A0 (en) | 1982-05-31 |
| AU8076582A (en) | 1982-09-16 |
| PH23415A (en) | 1989-08-07 |
| EP0060416B1 (de) | 1986-08-20 |
| DK103982A (da) | 1982-09-13 |
| ES8402590A1 (es) | 1984-02-01 |
| IL65232A (en) | 1986-01-31 |
| ES8308540A1 (es) | 1983-09-01 |
| ES510336A0 (es) | 1983-09-01 |
| KR830009020A (ko) | 1983-12-17 |
| IE820554L (en) | 1982-09-12 |
| CA1185244A (en) | 1985-04-09 |
| DE3272660D1 (en) | 1986-09-25 |
| JPS57159761A (en) | 1982-10-01 |
| US4576746A (en) | 1986-03-18 |
| IE52609B1 (en) | 1987-12-23 |
| EP0060416A1 (de) | 1982-09-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4476308B1 (de) | ||
| ATE21509T1 (de) | Beta-lactam-essigsaeure-derivate, verfahren zu deren herstellung und deren verwendung als zwischenverbindungen fuer 1-azabicyclo(3.2.0)hept- 2-en-antibiotika. | |
| PT77231B (en) | Process for the preparation of 2-nitro-1,1-ethenediamines having a hypotensive effect and their use for the preparation of pharmaceutical compositions with a hypotensive effect | |
| DE3854288D1 (de) | Cephalosporinderivate und Verfahren zur Herstellung von Cephem-Verbindungen. | |
| ATE54148T1 (de) | Neue cephalosporine und verfahren zu ihrer herstellung. | |
| DE3579894D1 (de) | Verfahren zur herstellung von aminothiazolessigsaeurederivaten. | |
| MA19841A1 (fr) | Procede de preparation de nouveaux derives de cephalosporines utilisables comme antibiotiques . | |
| IE820238L (en) | Carbapenem derivatives | |
| DE3469527D1 (en) | Nortropine derivative, process for its preparation and its use | |
| ATE41663T1 (de) | Verfahren zur herstellung von oxazolinen. | |
| FI884800A (fi) | Nytt foerfarande foer framstaellning av kefalosporiner. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |