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ATE213943T1 - Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden - Google Patents

Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden

Info

Publication number
ATE213943T1
ATE213943T1 AT93201656T AT93201656T ATE213943T1 AT E213943 T1 ATE213943 T1 AT E213943T1 AT 93201656 T AT93201656 T AT 93201656T AT 93201656 T AT93201656 T AT 93201656T AT E213943 T1 ATE213943 T1 AT E213943T1
Authority
AT
Austria
Prior art keywords
piperazine
reperfusion damage
acetamide derivatives
derivatives against
against reperfusion
Prior art date
Application number
AT93201656T
Other languages
English (en)
Inventor
Belle Herman Van
Laerhoven Willy Johannes C Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE213943T1 publication Critical patent/ATE213943T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166Streptokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Protection Of Pipes Against Damage, Friction, And Corrosion (AREA)
  • Dicing (AREA)
  • Golf Clubs (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Branch Pipes, Bends, And The Like (AREA)
  • Paper (AREA)
  • External Artificial Organs (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
AT93201656T 1989-11-22 1990-11-19 Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden ATE213943T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44014289A 1989-11-22 1989-11-22
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage

Publications (1)

Publication Number Publication Date
ATE213943T1 true ATE213943T1 (de) 2002-03-15

Family

ID=26664237

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93201656T ATE213943T1 (de) 1989-11-22 1990-11-19 Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden
AT90917677T ATE102831T1 (de) 1989-11-22 1990-11-19 Verfahren zur verhuetung oder zur begrenzung einer reperfusionsschaedigung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT90917677T ATE102831T1 (de) 1989-11-22 1990-11-19 Verfahren zur verhuetung oder zur begrenzung einer reperfusionsschaedigung.

Country Status (22)

Country Link
EP (2) EP0455789B1 (de)
JP (1) JP2574585B2 (de)
KR (1) KR0165686B1 (de)
AT (2) ATE213943T1 (de)
AU (1) AU632888B2 (de)
CA (1) CA2044143C (de)
CY (1) CY1869A (de)
DE (2) DE69033926T2 (de)
DK (2) DK0455789T3 (de)
ES (2) ES2173883T3 (de)
FI (1) FI109694B (de)
HK (1) HK115095A (de)
HU (1) HU215847B (de)
IE (1) IE65121B1 (de)
IL (1) IL96390A (de)
NO (2) NO304519B1 (de)
NZ (1) NZ236168A (de)
PT (2) PT95959B (de)
RU (1) RU2093156C1 (de)
SG (1) SG118494G (de)
WO (1) WO1991007967A2 (de)
ZA (1) ZA909345B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
RU2216549C2 (ru) * 1997-11-07 2003-11-20 Дайити Фармасьютикал Ко., Лтд. Пиперазин-циклодекстриновый комплекс и лекарственное средство, содержащее указанный комплекс
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
US6573264B1 (en) * 2000-10-23 2003-06-03 Cv Therapeutics, Inc. Heteroaryl alkyl piperazine derivatives
PT1395567E (pt) 2001-05-18 2009-03-26 Astrazeneca Ab Derivados de 4(fenil-piperazinil-metil)benzamida e sua utilização para o tratamento da ansiedade da dor ou de distúrbios gastrointestinais
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US20090018351A1 (en) * 2003-11-12 2009-01-15 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
DK1781631T3 (da) 2004-08-02 2012-05-14 Astrazeneca Ab Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
KR101900124B1 (ko) 2014-06-25 2018-09-18 전남대학교산학협력단 전복 박리용 조성물
KR101644299B1 (ko) 2014-07-22 2016-08-02 주식회사 엔바이로젠 오미자 및 삼채 추출물을 유효성분으로 포함하는 전복 박리용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ES2173883T3 (es) 2002-11-01
HU9102436D0 (en) 1991-12-30
FI109694B (fi) 2002-09-30
JP2574585B2 (ja) 1997-01-22
IE904209A1 (en) 1991-05-22
NO912511L (no) 1991-08-26
DK0577171T3 (da) 2002-06-03
CA2044143C (en) 2002-11-19
HUT58709A (en) 1992-03-30
ES2053208T3 (es) 1994-07-16
FI913433A0 (fi) 1991-07-16
IL96390A (en) 1995-06-29
SG118494G (en) 1994-11-25
NO912511D0 (no) 1991-06-26
EP0455789A1 (de) 1991-11-13
DE69033926D1 (de) 2002-04-11
DE69033926T2 (de) 2002-10-24
NO311701B1 (no) 2002-01-14
NO304519B1 (no) 1999-01-04
EP0577171A2 (de) 1994-01-05
DE69007471T2 (de) 1994-06-23
DE69007471D1 (de) 1994-04-21
IL96390A0 (en) 1991-08-16
PT95959B (pt) 1998-08-31
AU632888B2 (en) 1993-01-14
AU6876391A (en) 1991-06-26
PT102145B (pt) 2002-06-28
WO1991007967A2 (en) 1991-06-13
KR920700644A (ko) 1992-08-10
ZA909345B (en) 1992-08-26
PT102145A (pt) 1999-10-29
NO982078D0 (no) 1998-05-07
CY1869A (en) 1996-04-05
KR0165686B1 (ko) 1999-01-15
ATE102831T1 (de) 1994-04-15
EP0577171A3 (en) 1994-06-29
EP0455789B1 (de) 1994-03-16
PT95959A (pt) 1991-09-13
DK0455789T3 (da) 1994-04-05
HK115095A (en) 1995-07-21
NZ236168A (en) 1993-05-26
WO1991007967A3 (en) 1991-07-11
HU215847B (hu) 1999-04-28
NO982078L (no) 1991-08-26
CA2044143A1 (en) 1991-05-23
EP0577171B1 (de) 2002-03-06
RU2093156C1 (ru) 1997-10-20
IE65121B1 (en) 1995-10-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee